Inco庐 Nano Nickel Powder
Product Information
INCO Nano Nickel Powder (WHMIS Class B and Class D)
Inco INCO LIMITED
145 King Street West
Suite 1500
Material Toronto, ON
M5H 4B7
Chemtrec 24hr Emergency No. 1-800-424-9300
Safety INCO Nano Nickel Powder is used in catalyst applications.
Hazardous Ingredients
Data Oral LD50 - TLV1,2
Hazardous Calculated Percent 鈥?
C.A.S. No
mg/m3
Ingredients Composition rat
Nickel (Ni)* 40-100% 7440-02-0 40-100% >9000 1.5*
mg/kg
Sheet *As inhalable fraction
Physical Data
Grey, odourless powder with an average particle size of 5 to 20 nanometers.
Specific Sol. In H20
Ingredient Mol. Wt. m.p.掳C b.p.掳C
Gravity g/100ml
Ni 58.71 8.9 1453 2732 0
Fire or Explosion Hazard
Metal powders heat treated in reducing atmospheres may become spontaneously combustible.
Fire Flammable hazard. Any very finely divided particles (ultra-fine powder)
may burn in air when exposed to heat or flame.
Pyrophoric/
Autoignition Yes
Explosion This material, like most materials in powder form, is capable of
creating a dust explosion.
Stability and Reactivity
Hazardous Products
Nickel oxides, carbon monoxide, carbon dioxide, toxic and highly flammable nickel carbonyl.
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Nano Nickel Powder
Canadian
Updated: 01/07
Conditions to Avoid
Ignition sources, excess heat, dust generation, incompatibles and exposure to moisture.
Like other metals, nickel can react with acids to liberate hydrogen gas, which can form
explosive mixtures in air.
Like other metal powders, nickel powder can react explosively or incandescently with
Inco substances such as ammonium nitrate, perchlorates, phosphorous, selenium, sulphur, etc.
Under special conditions nickel can react with carbon monoxide in reducing atmospheres to
form nickel carbonyl, Ni(CO)4, a toxic gas.
Material Toxicological Properties3
Nickel
Safety LD50 ORAL RAT >9000 mg/kg
Inhalation May be harmful if inhaled. Material may be irritating to mucous membranes
and upper respiratory tract. May cause asthmatic attacks due to allergic
sensitization of the reparatory tract. Inhalation of fumes may cause metal
Data fume fever, which is characterized by flu-like symptoms with metallic taste,
fever, chills, cough, weakness, chest pain, muscle pain and increased white
blood cell count. May cause loss of smell.
Sheet The National Toxicology Program has listed nickel as reasonably anticipated
to be a carcinogen based on the production of injection site tumors. The
International Agency for Research on Cancer (IARC) found there was
inadequate evidence that metallic nickel is carcinogenic to humans but since
there was sufficient evidence that it is carcinogenic to animals, IARC
concluded that metallic nickel is possibly carcinogenic to humans. In 1997,
the ACGIH categorized elemental nickel as: A5 "Not Suspected as a Human
Carcinogen". Epidemiological studies of workers exposed to nickel powder
and to dust and fume generated in the production of nickel alloys and of
stainless steel have not indicated the presence of a significant respiratory
cancer hazard.
Evidence for the association of nickel compound exposures and cancer risk
comes mainly from workers in now obsolete nickel refining operations where
very high concentrations of airborne nickel, mostly present as oxidic or sub-
sulphate species at up to 100mg/m3 or more, were associated with excess
nasal and lung cancers.
The inhalation of nickel powder has not resulted in an increased incidence of
malignant lung tumors in rodents. Repeated intratracheal instillation of nickel
powder produced an increased incidence of malignant lung tumors in rats.
Repeated intratracheal instillation of nickel powder did not produce an
increased incidence of malignant lung tumors in hamsters when administered
at the maximum tolerated dose. Single intratracheal instillations of nickel
powder in hamsters at doses near the LD50 produced an increased
incidence of fibro sarcomas, mesotheliomas and rhabdomyosarcomas.
Inhalation of nickel powder at concentrations 15 times the TLV irritated the
respiratory tract in rodents.
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Nano Nickel Powder
Canadian
Updated: 01/07
Inhalation of nickel may induce asthma. This effect is rare, it has been
reported in welders where exposures to nickel are often mixed with other
chemical substances. Persons with a known history of nickel sensitive
asthma should avoid such contact.
Skin Contact Prolonged and intimate contact with metallic nickel may cause irritation to the
Inco skin and nickel sensitivity, which may result in allergic skin rashes.
One case has been reported of asthma induced by external exposure to a
nickel-containing skin clip and by skin contact with nickel.
Material Wounds Nickel metal powder has caused tumors at the site of injection in rodents.
However, studies do not suggest a significant risk for humans from nickel-
containing prostheses.
Safety Ingestion May be harmful if swallowed. May cause gastrointestinal irritation with
nausea, vomiting and diarrhea. May cause tremors and convulsions.
Ingestion of large amounts may cause gastroenteritis.
Data The U.S. National Institute for Occupational Safety and Health (NIOSH)
concluded there is no evidence that nickel and its inorganic compounds are
carcinogenic when ingested. The U.S. Food and Drug Administration has
affirmed that nickel is generally recognized as safe (GRAS) as a direct
Sheet human food ingredient.
Pre-existing
Conditions Prolonged and intimate skin contact can cause an allergic skin rash in
previously sensitized individuals.
Reproductive
Toxicity Animal experiments indicate that soluble nickel ingestion causes adverse
effects on fetal development at a threshold oral exposure of 2.2 mg/
Ni/kg/day by pregnant rats. Data are insufficient to determine if this effect
occurs in humans and no regulatory agency has classified soluble forms of
nickel as reproductive risks for humans.
Preventative Measures
Do not inhale powder. Keep in a tightly closed container, away from heat, sparks, electrostatic
discharge and open flame. Store in a cool, dry place. Protect from physical damage. Handle and store
under nitrogen and avoid exposure to air and moisture. Isolate from incompatible substances.
Containers of this material may be hazardous when empty since they retain product residues (dust,
solids); observe all warnings and precautions listed for the product.
Ventilation is normally required when handling or using this product to keep exposure to airborne nickel
below the exposure limit. If ventilation alone cannot so control exposure, use NIOSH-approved
respirators selected according to the Selection, Care and Use of Respirators CSA Z94.4-M1993.
Maintain airborne nickel levels as low as possible.
Avoid contact with skin, eyes and clothing. Avoid prolonged or repeated exposure. Wear suitable
gloves. Wash skin thoroughly after handling. Launder clothing and gloves as needed.
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Nano Nickel Powder
Canadian
Updated: 01/07
If spilled, collect spills by wet sweeping or by vacuuming with the vacuum exhaust passing through a
high efficiency particulate arresting (HEPA) filter if the exhaust is discharged into the workplace. Wear
appropriate NIOSH-approved respirators if collection and disposal of spills is likely to cause the
concentration of airborne contaminants to exceed the exposure limits.
First Aid Measures
Inco If exposure to nickel carbonyl is suspected, seek medical attention immediately. For skin rashes, seek
medical attention. Cleanse wounds thoroughly to remove any particles.
Ingestion Do not induce vomiting. Wash out mouth with water and give 2-4 cups of
Material milk or water. Never give anything by mouth to an unconscious person.
Seek medical attention immediately.
Disposal Considerations
Safety Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the
material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and
scrubber. Processing, use our contamination of this product may change the waste management
options. Observe all federal, state, and local environmental regulations.
Data
Transport Information
US DOT Canada TDG
Sheet Shipping Name Metal Powder, Flammable, NOS (Nickel) Metal Powder, Flammable, NOS (Nickel)
Hazard Class 4.1 4.1
UN Number UN3089 UN3089
Packing Group II II
Preparation Information
Prepared by:
INCO LIMITED
Product Stewardship and Quality
Tel. No.: (416) 361-7801
Note:
Inco believes that the information in this Material Safety Data Sheet is accurate. However, Inco
makes no express or implied warranty as to the accuracy of such information and expressly
disclaims any liability resulting from reliance on such information.
Footnotes:
庐 Trademark of the Inco family of companies.
1 Threshold Limit Value of the American Conference of Governmental Industrial Hygienists.
2 Exposure Limits for user operations will depend on the relevant governmental regulations.
3 Describes possible health hazards of the product supplied. If user operations change it to other
chemical forms, whether as end products, intermediates or fugitive emissions, the user must
determine the possible health hazards of such forms.
1
Nano Nickel Powder
Canadian
Updated: 01/07
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