MATERIAL SAFETY DATA SHEET
IDENTIFICATION
Stratagene Date of Last Update: 6/07/2007
11011 N. Torrey Pines Rd. Phone #: 800-894-1304
La Jolla, CA 92037 Fax #: 858-535-0071
Part # : 1008-13 Ampicillin
CAS # : 69-52-3
HAZARDOUS COMPONENTS
Chemical Name & Synonyms: Ampicillin or Ampicillin Derivative, Ampicillin Sodium Crystalline,
(Alpen-N, Amcill-S, D(-)-Alpha-Aminobenzylpenicillin sodium salt, Ampicillin sodium, Ampicillin
sodium salt, Binotal sodium, Citteral, Domicillin, Omnipen-N, Pen A/N, Penbritin-S, Penialmen,
Polycillin-N, Principen/N, Sodium D-(-)-alpha-aminobenzylpenicillin, Sodium Ampicillin, Sodium
Binotal, Sodium P-50)
OSHA PEL Limits: N/A
ACGIH TLV: N/A
Other Limits Recommended: N/A
KIT Ampicillin -containing component %
16.7
300020 Amp Tabs鈩? Ampicillin Tablets 300020-61 Amp Tabs鈩? Ampicillin Tablets
16.7
300021 Amp Tabs鈩? Ampicillin Tablets 300021-61 Amp Tabs鈩? Ampicillin Tablets
100
300024 Turbo Amp鈩? Powder 300024-51 Turbo Amp鈩? Powder
TOXICITY DATA
Irritation Data
No data available.
Toxicity Data
ORL-RAT LD50: >5314 mg/kg BJPCAL 18,356,1962
IPR-RAT LD50: 7400 mg/kg TXAPA9 18,185,1971
SCU-RAT LD50: >5314 mg/kg BJPCAL 18,356,1962
ORL-MUS LD50: >5314 mg/kg BJPCAL 18,356,1962
IPR-MUS LD50: 5700 mg/kg TXAPA9 18,185,1971
SCU-MUS LD50: >5314 mg/kg BJPCAL 18,356,1962
Reviews, Standards, and Regulations
OEL鈥揗AK
ARC Cancer Review: Animal Limited Evidence IMEMDT 50,153,1990
IARC Cancer Review: Human Inadequate Evidence IMEMDT 50,153,1990
IARC Cancer Review: Group 3 IMEMDT 50,153,1990
NOES 1983: HZD X3564; NIS 2; TNF 549; NOS 8; TNE 23006; TFE 18439
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Target Organ Data
Gastrointestinal (Hypermotility, Diarrhea)
Gastrointestinal (Other changes)
Only selected Registry of Toxic Effects of Chemical Substances (RTECS) data is presented here.
See actual entry in RTECS for complete information.
RTECS # XH8400000
4-Thia-1-Azabicyclo(3.2.0)Heptane-2-Carboxylic Acid,
6-(2-Amino-2-Phenylacetamido)-3, 3-Dimethyl-7-Oxo-, Sodium Salt, D-(-)-
Health Hazard Data
*Warning*
There are reports of serious and sometimes fatal hypersensitivity (Anaphylactic) reactions
occurring in people receiving penicillin therapy by the parenteral route although it has also
occurred via oral administration. These reactions usually occur in individuals who have a
history of sensitivity to multiple allergens, asthma, hay fever, or urticaria. Ingestion has
resulted in nausea, vomiting, diarrhea, glossitis, stomatitis, enterocolitis,
pseudomembraneous colitis. Hypersensitivity reactions: Erythematous maculopapular
rashes, erythema multiforme, urticaria, and exfoliative dermatitis.
Acute Effects
May be harmful by inhalation, ingestion, or skin absorption.
May cause skin irritation.
May cause eye irritation.
Material may be irritating to mucous membranes and upper respiratory tract.
May cause allergic reaction.
Target Organ(s): Blood
Chronic Effects
This product is or contains a component that is not classifiable as to its carcinogenicity based on
its IARC, ACGIH, NTP, or EPA classification.
First Aid
In case of eye contact, immediately flush eyes with copious amounts of water for at least 15
minutes.
In case of skin contact, immediately wash skin with soap and copious amounts of water.
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult,
give oxygen.
If swallowed, wash out mouth with water provided person is conscious.
Wash contaminated clothing before reuse.
In all cases, contact a physician immediately.
Physical Data
Appearance and Odor
Solid.
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Fire and Explosion Hazard Data
Extinguishing Media
Water spray.
Carbon dioxide, dry chemical powder, or appropriate foam.
Special Firefighting Procedures
Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and
eyes.
Unusual Fire and Explosion Hazards
Emits toxic fumes under fire conditions.
Avoid sparks, heat and/or open flame.
Reactivity Data
Incompatibilities
Strong oxidizing agents.
Hazardous Combustion or Decomposition Products
Toxic fumes of Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides.
Stability
No data available.
Hazardous polymerization
No data available.
Spill or Leak Procedures
Steps to be taken if Material is Released or Spilled
Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.
Sweep up, place in a bag, and hold for waste disposal.
Avoid raising dust.
Ventilate area and wash spill site after material pickup is complete.
Waste Disposal Method
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator
equipped with an afterburner and scrubber.
Observe all federal, state, and local environmental regulations.
Precautions to be Taken in Handling and Storage
Label Precautionary Statements
Harmful.
May cause sensitization by inhalation or skin contact.
Target Organs(s): Blood, liver, kidneys.
Do not breathe vapor spray.
Wear suitable protective clothing.
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Exposure Controls and Personal Protection:
Wear appropriate NIOSH/MSHA-approved respirator, chemical-resistant gloves, safety goggles,
and other protective clothing.
Use only if a safety shower and eye bath are available.
Use only in a chemical fume hood.
Do not breathe dust.
Do not get in eyes, on skin, or on clothing.
Avoid prolonged or repeated exposure.
Wash thoroughly after handling.
Keep tightly closed.
Store in a cool dry place.
*To the best of our knowledge, the chemical, physical, and toxicological properties of this
compound have not been investigated.*
The above information is believed to be correct but does not purport to be all inclusive and shall be used
only as a guide. Stratagene shall not be held liable for any damage resulting from handling or from contact
with the above product.
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