MATERIAL SAFETY DATA SHEET
IDENTIFICATION
Stratagene Date of last update: 9/15/05
11011 N. Torrey Pines Rd. Phone #: 800-894-1304
La Jolla, CA 92037
Part # : 1073-13 d-Limonene
CAS # : 5989-27-5
HAZARDOUS COMPONENTS
Chemical Name & Synonyms: d-Limonene, Citrus Terpenes
OSHA PEL Limits: N/A
ACGIH TLV: N/A
Other Limits Recommended: N/A
KIT d-Limonene-containing component %
鈮?99% (v/v)
400809 Absolutely RNA庐 FFPE Kit 400809-7 De-paraffinization Reagent
TOXICITY DATA
RTECS#:
CAS# 5989-27-5: GW6360000
LD50/LC50:
CAS# 5989-27-5:
Draize test, rabbit, skin: 10%/24H Mild;
Oral, mouse: LD50 = 5600 mg/kg;
Oral, rat: LD50 = 4400 mg/kg;
Skin, rabbit: LD50 = >5 gm/kg;
Carcinogenicity:
CAS# 5989-27-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology: No information available.
Teratogenicity: Not known to be teratogenic.
Reproductive Effects: See actual entry in RTECS for complete information.
Mutagenicity: d-Limonene was not mutagenic in 4 strains of S. typhimurium, did not significantly increase
the number of Tft-resistant cells in the mouse L5178Y/TK+/- assay, and did not induce chromosomal
aberrations or SCEs in cultured CHO cells.
Neurotoxicity: No information available.
Other Studies:
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Health Hazard Data
Effects of Overexposure:
Skin: Prolonged or repeated contact may cause irritation, defatting, or dermatitis.
Eyes: Eye irritant. May cause redness, swelling, or blurred vision.
Inhalation: May be irritating to the nose, throat, and lungs. Large amounts can cause headache, nausea,
dizziness, weakness, and fatigue.
Ingestion: Can cause irritation of the gastrointestinal tract, nausea, vomiting, and diarrhea. Aspiration of
material into the lungs can cause pneumonitis.
First Aid:
Skin: Remove contaminated clothing. Wash with soap and water. Seek medical attention if irritation
persists.
Eyes: Flush with large quantities of water, holding eyelids open. Seek medical attention.
Inhalation: Get to fresh air. If breathing is difficult, give oxygen. Seek medical attention if symptoms
persist.
Ingestion: Do not induce vomiting. Seek medical attention immediately.
Physical Data
Boiling Point: 310掳F pH: N/A
Specific Gravity: 0.84 Initial Vapor Pressure: 2 mmHg at 68掳F
% Volatile: 100 Vapor Density (Air = 1): 0.012
Evaporation Rate (Water = 1): <1 Solubility in Water: Nil
Physical Description: Yellow to water-white oil
Fire and Explosion Hazard Data
Flash Point (Method Used): 115掳F (TCC)
Flammable Limits UEL: 6.1 Flammable Limits LEL: 0.7
Extinguishing Media: Foam, carbon dioxide, dry chemical.
Special Firefighting Procedures: Do not use water. Handle as oil fire.
Unusual Fire and Explosion Hazards: Drums heated by fire can explode.
Reactivity Data
Incompatibilities: Strong oxidizers and acidic agents.
Hazardous Combustion or Decomposition Products: Carbon monoxide possible if burned.
Stability: Stable.
Hazardous Polymerization: None.
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Spill or Leak Procedures
Steps to be taken if Material is Released or Spilled:
Floors will become slippery. Avoid walking in product. Keep unessential personnel away. Mop up or
otherwise absorb and hold disposal. Avoid discharge to sewer or open waterways.
Waste Disposal Method:
Any method in accordance with local, state and federal laws. Best method is to recycle or reuse for
intended purpose. If discarded, this material and containers should be treated as hazardous waste based
on the characteristic of ignitability as defined under federal RCRA regulations (40 CFR 261). Consult
local authorities for disposal in public sewer. Do not dispose of into storm drain, stream, river or to
ground. Rinse container thoroughly before discarding in trash.
Precautions to be Taken in Handling and Storage
Combustible liquid.
Keep away from excessive heat, spark or open flames.
Do not smoke while handling.
Keep out of reach of children.
For use by trained personnel only.
Keep container closed during storage.
For institutional and industrial use only.
Avoid contact with eyes, skin and clothing.
Wear rubber gloves and eye protection when handling.
Avoid breathing of vapors.
Use in well-ventilated area.
Empty container may contain explosive or flammable vapors.
Special Protection Information
Respiratory Protection: Use with adequate ventilation. Use NIOSH approved Hydrocarbon (Organic vapor)
canister respirator when using in confined areas.
Ventilation Requirements: Provide explosion-proof ventilation to keep TLV of Section 2 ingredients below
acceptable limit.
Protective Gloves: Solvent proof rubber or viton.
Eye Protection: Chemical splash goggles or full-face shield.
Other Protective Equipment: Eyewash station should be nearby. Protective chemical resistant outerwear
when conditions exist where body contact is possible.
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Regulatory Information
SARA Title III - Section 311/312 -Hazard Categories:
Yes 鈥揊ire Hazard
No 鈥? Sudden Release of Pressure Hazard
No 鈥? Reactivity Hazard
Yes 鈥揑mmediate (acute) Health Hazard
No 鈥? Delayed (chronic) Health Hazard
HMIS Hazardous Materials Identification System Ratings:
Health: 1
Flammability: 2
Reactivity: 0
Personal Protection B
This product contains the following toxic chemical(s) subject to the reporting requirements of section 313
of the Emergency Planning and Community Right-To-K now Act of 1986 and of 40 CFR 372: None
This product contains the following chemical(s) which have been established to be either a carcinogen or
suspected carcinogen: None
The above information is believed to be correct but does not purport to be all inclusive and shall be used
only as a guide. Stratagene shall not be held liable for any damage resulting from handling or from contact
with the above product.
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