MATERIAL SAFETY DATA SHEET DIPHENYLAMINE
PRODUCT CODE NUMBER(S): 4870-5
PRODUCT IDENTIFICATION Hazardous Decomposition Products: NOx, COx, toxic
and irritating products and fumes.
Chemical Name and Synonyms: Diphenylamine;
N-Phenylbenzeneamine; Diphenylaniline; DPA FIRE AND EXPLOSION DATA
Chemical Family: Secondary aromatic amines
Flammability: Can burn if strongly heated. As with most
Chemical Formula: (C6H5)2NH
organic compounds, fine dust dispersed in air in the pres-
Product Use: Laboratory chemical ence of an ignition source is a potential dust explosion
Manufacturer鈥檚 Name and Address: hazard
Caledon Laboratories Ltd. Extinguishing Media: Dry powder, carbon dioxide. Water,
applied carefully as a spray or fpg, may cause frothing,
40 Armstrong Avenue
which will blanket and smother the fire. Use water spray or
Georgetown, Ontario L7G 4R9
fog to cool fire-exposed containers, disperse dust or fumes,
Telephone No: (905) 877-0101
and flush material away from fire. Fight fire from upwind,
Fax No: (905) 877-6666 from a safe distance. Firefighters must wear full protective
equipment (MSHA/NIOSH approved positive pressure
Emergency Telephone No: CANUTEC (613) 996-6666
self-contained breathing apparatus) and clothing (chemical
HAZARDOUS INGREDIENTS OF MATERIALS splash suit) sufficient to prevent inhalation and contact.
Bunker Gear will not be adequate.
Flash Point (Method Used): 153掳C
Ingredients % TLV Units CAS No.
Autoignition Temperature: 634掳C
3
Diphenylamine >97 10 mg/m 122-39-4
Upper Flammable Limit (% by volume): Not available
PHYSICAL DATA Lower Flammable Limit (% by volume): Not available
Hazardous Combustion Products: NOx, COx, toxic and ir-
Physical State: Solid
ritating products and fumes.
Odour and Appearance: White to off-white crystals,
Sensitivity to Impact: None identified
charactaeristic floral odour
Sensitivity to Static discharge: As with most organic pow-
Odour Threshold (ppm): 0.05 ppm, good warning proper-
ders, mixtures of dust with air may be sensitive under
ties TLV >10x odour threshold
certain conditions, when ignited by an electrostatic or other
Vapour Pressure (mm Hg): 1 mm Hg @ 108.3掳C
high-voltage spark, or other ignition source.
Vapour Density (Air = 1): 5.82
TOXICOLOGICAL PROPERTIES AND HEALTH DATA
Evaporation Rate: Not available
Boiling Point (degrees C): 302掳C
Toxicological Data:
Melting Point (degrees C): 52-54掳C
LD50: (oral, guinea pig) 300 mg/kg; (oral, rat) 1,120 mg/kg
pH: Not available
LDLO: (human) 500 mg/kg
Specific Gravity: 1.159 at 20掳C
LC50: Not available
Coefficient of Water/Oil distribution: LogP(oct)=3.22
SHIPPING DESCRIPTION Effects of Acute Exposure to Product:
May be fatal by all routes of exposure.
UN: Not regulated
Inhaled: Toxic. Irritates the upper respiratory tract, causing
T.D.G. Class: Not regulated
coughing, difficult breathing. May cause methemoglobin-
Pkg. Group: Not regulated emia, with cyanosis (bluish skin due to deficient oxygenation
of the blood), nausea and vomiting. May progress to cause
REACTIVITY DATA blood and central nervous system effects, anemia,
reticulocytosis, hematuria, weakness, depression, head-
Chemical Stability: Stable, but may discolour on exposure
ache, respiratory distress, irregular heart rate, eventual
to light.
coma and death. Symptoms may be delayed for two to four
Incompatibility with other substances: May react vio-
(2-4) hours or longer. Effects are reversible when exposure
lently with strong oxidizers, with risk of fire and explosion.
stops; however, severe overexposure can be fatal.
May react vigorously or violently with strong acids,
In contact with skin: Dust or solutions may be irritating to
isocyanates, organic anhydrides, aldehydes. May react with
skin, causing redness and itching. Severity of effects de-
hexa- or trichloromelamine with or without flame, causing
pends on degree and duration of exposure. Solutions may
fire, fume or explosion.
be absorbed with systemic effects as in 鈥淚nhaled鈥?.
Reactivity: Avoid temperature above 153掳C, ignition
In contact with eyes: Causes moderate to severe irritation,
sources, incompatible materials, generation of dust, expo-
with redness, tearing, pain, possible damage to conjunctiva
sure to light.
DIPHENYLAMINE
MSDS
CODE: 4870-5
or cornea. Severity of effects depends on degree and dura- bond equipment and containers. Use the smallest amount possi-
tion of exposure. ble for the purpose, in a designated area with adequate
ventilation. Use good housekeeping to prevent accumulations of
Ingested: Toxic. Ingestion may cause systemic poisoning
dust. Avoid contact with skin and eyes. Avoid inhalation. Wash
with symptoms similar to those of inhalation. May be fatal.
thoroughly after handling. Empty containers may contain hazard-
Absorption into the body by ingestion or inhalation leads to
ous residues; treat with caution.
methemoglobin formation which may cause cyanosis. On-
set may be delayed 2 to 4 hours or longer. Storage Requirements: Store in sturdy, labelled containers, in a
cool, dry, well-ventilated area, out of light, and away from heat
and ignition sources. Store away from incompatible materials.
Effects of Chronic Exposure to Product:
Protect from damage. Inspect regularly for signs of leaking.
Prolonged exposure can cause chronic methemoglobinemia Keep containers tightly closed. Protect from light.
with symptoms as in 鈥淚nhaled鈥?, above. May cause skin sen-
FIRST AID MEASURES
sitization.
Persons with pre-existing skin or eye disorders, or impaired
Specific Measures:
liver or respiratory function may be more susceptible to the
effects of this substance. Eyes: Flush thoroughly with running water for at least fifteen (15)
minutes, holding eyelids open while flushing. Take care not to
Carcinogenicity: ACGIH: A4 (not classsifiable as human
flush contaminated water into unaffected eye. Wear protective
carcinogen).
gloves to avoid contact during first aid procedures. Get medical
Teratogenicity: No human nformation available. Has
attention immediately.
caused effects in rats in laboratory testing.
Skin: Remove contaminated clothing, including watches, rings,
Reproductive Effects: No human information available.
belts, and shoes. Wear impervious gloves to avoid contact. Flush
Decreased litter size has occurred in studies with rats.
skin with plenty of running water for ten to twenty (10-20) min-
Mutagenicity: No human or animal information available.
utes, until no trace of chemical remains. Get medical attention.
Not mutagenic in Ames test.
Decontaminate clothing completely before reuse, or discard. In-
Synergistic Products: Reacts with nitrosating agents to
form laundry personnel of hazard.
form nitrosamines, which have been shown to cause cancer
Inhalation: Immediately move victim to fresh air (caution must
in animal testing.
be used by rescuers to avoid exposure to contaminating fumes).
Eliminate ignition sources. Give oxygen and get medical attention
PREVENTIVE MEASURES
immediately for any breathing difficulty, or for any indication of
cyanosis (blueness in skin). If breathing has stopped, begin artifi-
Engineering Controls: Local exhaust ventilation required.
cial respiration immediately. Effects of methemoglobinemia may
Respiratory Protection: Dust/mist mask. Up to 10x TLV,
be delayed for two to four (2-4) hours or longer; continue to moni-
or the maximum use specified by the respirator supplier,
tor for at least that long. If symptoms develop, get medical
whichever is lowest, NIOSH/MSHA approved half- face
attention immediately.
dust/mist respirator. Up to 50x TLV, or the maximum use
Ingestion: Get medical attention. If victim is alert, conscious,
specified by the respirator supplier, whichever is lowest,
and NOT convulsing, rinse mouth thoroughly with water, and
NIOSH/MSHA approved full face-piece dust/mist respirator.
give 2 to 4 glasses of water to drink to dilute. Induce vomiting im-
Higher or unknown concentrations, or for fire or spill condi-
mediately under medical supervision, by sticking a finger down
tions, self-contained breathing apparatus, or full face-piece,
the throat ot giving syrup of ipecac. If signs of
positive-pressure supplied-air respirator.
methemoglobinemia are present (bluish lips and skin), give oxy-
Eye Protection: Chemical safety goggles, face-shield.
gen and get medical attention immediately.
Skin Protection: Impervious rubber gloves. Other impervi-
ous clothing, apron, sleeves, coveralls, boots as required to
REFERENCES USED
prevent contact.
CCINFO disc: Cheminfo, MSDS鈥檚, June 2006
Other Personal Protective Equipment: Safety shower
and eye-wash fountain in work area. Sax, Lewis: Hawley鈥檚 Condensed Chemical Dictionary, 11th ed.,
Leak and Spill Procedure: Evacuate area. If dust is pres- 1987
ent, eliminate all sources of ignition and all combustible Suppliers鈥? Material Safety Data Sheets
materials. Cleanup personnel must be thoroughly trained in
the handling of hazardous materials, and must wear protec-
ADDITIONAL INFORMATION
tive equipment and clothing sufficient to prevent inhalation
and contact with skin, eyes and clothing. Mix with sand or Date Issued: August 2000
soda ash in a ratio of 9:1, transfer carefully into container
Revision: June 2006
and arrange removal by disposal company. Avoid raising
MSDS: 4870-5
dust. Wash site of spillage thoroughly with water and deter-
gent. Prevent material from entering sewers or waterways. Proposed WHMIS Designation: D1B, D2B
Contaminated absorbent may pose the same hazards as the
chemical; treat with caution. Prepared by: Caledon Laboratories Ltd. (905) 877-0101
Waste Disposal: Follow all federal, provincial and local Caledon Laboratories Ltd. believes the information contained
regulations for disposal. herein is reliable and accurate. Caledon makes no warranty with re-
Handling Procedures and Equipment: TOXIC, IRRI- spect thereto and expressly disclaims all liability for reliance
TANT, COMBUSTIBLE DUST. Workers using this chemical thereon. Such information is solely for your consideration, investi-
must be properly trained in its hazards and its safe use, and
gation, and verification.
must wear appropriate protective clothing and equipment.
Avoid generating dust. If there is dust, keep away from
heat, sparks, and all sources of ignition; avoid the accumula-
tion of static charge, use anti-sparking tools and ground and
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