MATERIAL SAFETY DATA SHEET PHENOL SATURATED
PRODUCT CODE NUMBER(S): 6910-5, 6920-5
PRODUCT IDENTIFICATION Reactivity: Stable under normal temperatures and pressures; avoid
heat, flame or other ignition sources; protect from light and air.
Chemical Name and Synonyms: Phenol, saturated, pH 4.5 or pH Vapour-air mixtures are explosive above flash point.
6.6/7.9 Hazardous Decomposition Products: COx
Chemical Family: Phenol with buffers
FIRE AND EXPLOSION DATA
Chemical Formula: Mixture
Product Use: Laboratory reagent
Flammability: Combustible. Can form explosive mixtures with air at
Manufacturer鈥檚 Name and Address: or above 79掳C. Vapours may travel to distant source of ignition and
Caledon Laboratories Ltd. flash back. Hot surfaces may be enough to ignite liquid in the ab-
40 Armstrong Avenue sence of sparks or flame.
Georgetown, Ontario L7G 4R9 Extinguishing Media: Water spray, carbon dioxide, dry chemical,
鈥渁lcohol鈥? or polymer foam. Water as spray or fog can be used to cool
Telephone No: (905) 877-0101
containers and disperse vapours or flush spills away from ignition
Fax No: (905) 877-6666
sources. Fight fire from upwind, from a safe distance Firefighters
Emergency Telephone No: CANUTEC (613) 996-6666 must wear NIOSH/OSHA approved full face-piece, positive-pressure
self-contained breathing apparatus and encapsulating chemical
HAZARDOUS INGREDIENTS OF MATERIALS splash suit (Bunker Gear is not adequate).
Flash Point (Method Used): 79掳C (CC) (phenol)
Ingredients % TLV Units CAS No.
Autoignition Temperature: 605掳C (phenol)
Phenol 80-90 5 ppm 108-95-2 Upper Flammable Limit (% by volume): 8,6 (phenol)
(skin can contribute to overall exposure) Lower Flammable Limit (% by volume): 1.8 (phenol)
10 mg/m3
Tris <10 77-86-1 Hazardous Combustion Products: COx
EDTA <1 Not established 60-00-4 Sensitivity to Impact: None identified
Sensitivity to Static discharge: Liquid will probably not accumulate
PHYSICAL DATA static charge, or be ignited by static discharge. Mixtures of vapour
with air may be ignited by static discharge under certain circum-
Physical State: Liquid
stances.
Odour and Appearance: Thick, colourless to light pink liquid,
sweet, tarry odour TOXICOLOGICAL PROPERTIES AND HEALTH DATA
Odour Threshold (ppm): 0.012 ppm (detection); 0.057 ppm (rec-
ognition) Toxciity information is based on the phenol component.
Vapour Pressure (mm Hg): 0.36 mm @ 20掳C (phenol) Minimal hazards associated with the other components are
insignificant in relation to phenol hazards.
Vapour Density (Air = 1): 3.24 (phenol
Evaporation Rate: < 1 (Butyl acetate = 1) (phenol)
Toxicological Data:
Boiling Point (degrees C): 182掳C (phenol)
LD50: (oral, rat) 320 mg/kg, 530 mg/kg (2 and 5% solutions); (dermal,
Melting Point (degrees C): 41掳C (phenol)
pig) 500 mg/kg (liquified, 45掳C)
pH: 4.5 to 7.9
LC50: (mouse) 177 mg/m3/3h; (rat) 316 mg/m3/3h
Specific Gravity: 1.05 @ 20掳C
Coefficient of Water/Oil distribution: LogP(oct)=1.46 (phenol) Effects of Acute Exposure to Product:
SHIPPING DESCRIPTION Inhaled: VERY TOXIC. Vapour and mist are destructive to all tissue,
causing severe burns of the nose and throat; absorption causes CNS
UN: 2821 effects (nausea, dizziness, headache), kidney and liver damage. Brief
exposure can cause irreversible injury or death as a result of spasm
T.D.G. Class: 6.1
of larynx and bronchi, chemical pneumonitis and pulmonary edema.
Pkg. Group: II
Vapours are heavier than air and can collect in low-lying areas, dis-
placing air.
REACTIVITY DATA
In contact with skin: CORROSIVE, VERY TOXIC. Liquid and dust
are extremely corrosive; hazard increases with phenol concentration;
Chemical Stability: Moderately stable.
aqueous solutions over 5% are corrosive and toxic. Vapour and liquid
Incompatibility with other substances: Acetaldehyde: violent
can be readily absorbed through the skin in toxic or lethal amounts;
condensation reaction. 1,3-Butadiene, borontrifluoride diethyl ether
effects include shock, collapse, coma, convulsion, kidney and liver
complex, sodium nitrate, trifluoroacetic acid: intense exothermic re-
damage and death. Moisture on skin (perspiration) accelerates tissue
action. Calcium hypochlorite: intense exothermic reaction with
destruction. Causes local anesthesia; severe chemical burns and poi-
ignition; Formaldehyde: temperature and pressure increase in
soning can occur with little or no pain.
closed container. May react explosively with strong oxidizers, so-
In contact with eyes: CORROSIVE. Vapours and concentrated so-
dium nitrite, peroxodisulfuric acid, peroxomonosulfuric acid, when
lutions are severely irritating to eyes. Can cause conjunctival swelling,
heated, aluminum chloride and nitrobenzene mixture under carbon
permanent corneal damage and blindness.
monoxide. Attacks many plastics, rubbers, coatings. Emits flamma-
ble hydrogen gas in contact with reducing agents. Corrosive to Ingested: CORROSIVE, VERY TOXIC. Causes severe burns of the
aluminum, lead, zinc. mouth and throat, systemic effects as in 鈥淚n Contact with Skin鈥?; lethal
dose may be as little as 15 mL.
MSDS PHENOL SATURATED
CODE: 6910-5, 6920-5
Effects of Chronic Exposure to Product: all sources of ignition, and all incompatible materials. Keep containers
tightly closed and when opening, use extreme caution. Keep separate
Long-term exposure to phenol may cause dermatitis, darkening of from other materials. Protect from damage. Inspect frequently for
skin and urine, muscular pains, weight loss, anorexia, , headache, signs of damage or leaking. Storage area should have raised sills or
nausea, vomiting, diarrhea, weakness, kidney and liver damage and ramps and a trench which drains to a safe location, and sealed floors
skin sensitization. May be fatal. May aggravate cardiovascular, liver to prevent absorption. Empty containers may contain hazardous resi-
and kidney disease, existing respiratory conditions, such as asthma, dues; treat with extreme care.
bronchitis, inflammatory or fibriotic respiratory disease.
FIRST AID MEASURES
Carcinogenicity: Not classifiable as carcinogenic (IARC, ACGIH).
Teratogenicity: No human information available. Animal studies in-
Specific Measures:
dicate probably not teratogenic at levels not toxic to mother.
Eyes: Immediately flush eyes with warm running water for at least
Reproductive Effects: No human information available. In a
sixty (60) minutes, holding eyelids open while flushing. DO NOT IN-
two-generation study with rats, no significant effects on reproductive
TERRUPT FLUSHING. Use neutral saline to flush as soon as it is
performance (RTECS No. SJ3325000).
Mutagenicity: Mutagenicity tests are inconclusive; both positive and available. Take care not to flush contaminated water into unaffected
eye. Wear protective gloves to avoid contact during first aid proce-
negataive results, in cultured animal cells and bacteria.
Synergistic Products: Phenol can promote the development of skin dures. GET MEDICAL ATTENTION IMMEDIATELY.
Skin: Immediately remove all contaminated clothing (including rings,
cancer when applied with known carcinogens.
watches, belts, and shoes) under running water. Wear gloves and
PREVENTIVE MEASURES other protective clothing sufficient to prevent ANY contact with chemi-
cal. Flush exposed area with large amounts of gently running,
Engineering Controls: Corrosion-resistant, non-sparking, grounded lukewarm water for at least sixty (60) minutes. If polyethylene gly-
ventilation system, separate from other ventilatiaon systems. col-300 is available, stop water flushing after the chemical is removed
Respiratory Protection: Use only in a fumehood. To 50 ppm: and immerse the affected part in PEG-300, or if immersion is not pos-
NIOSH/OSHA approved chemical cartridge respirator with organic sible, spray or swab with it continuously until medical help arrives.
vapour cartridge and dust and mist filter. To 125 ppm: supplied air GET VICTIM TO MEDICAL FACILITY IMMEDIATELY. If breathing has
respirator operated in a continuous flow mode or powered stopped give artificial respiration.If breathing and pulse are absent,
air-purifying respirator with organic vapour cartridge and dust and give CPR. Use mouth guards to prevent contact. Keep contaminated
mist filter. To 250 ppm: full facepiece chemical cartridge respirator clothing in closed, labelled containers until it can be safely discarded.
with organic vapour cartridge and high-efficiency particulate filter or Inhalation: IMMEDIATELY remove to fresh air (caution must be used
powered, full face-piece, air-purifying respirator with organic vapour by rescuers to avoid exposure). Give oxygen for breathing difficulty. If
cartridge and high-efficiency particulate filter. For higher or unknown breathing has stopped give artificial respiration. If breathing and pulse
concentrations, as in fire or spill conditions, self-contained breathing are absent, give CPR. Use mouth guards to prevent contact. GET
apparatus with full facepiece operated in a positive pressure mode, or MEDICAL ATTENTION IMMEDIATELY. Stay with casualty until medi-
positive-pressure, full face-piece supplied-air respirator with an auxil- cal assistance is reached.
iary positive-pressure self-contained breathing apparatus. Ingestion: DO NOT INDUCE VOMITING. DANGER OF ASPIRATION
Eye Protection: Chemical safety goggles and faceshield. WITH EMESIS. If casualty is alert and not convulsing, rinse out mouth
with water and give 15 to 30 cc of castor oil or vegetable oil. GET
Skin Protection: Viton鈩?, Viton鈩?/butyl rubber, Trellcehm鈩PS,
MEDICAL ATTENTION IMMEDIATELY. If spontaneous vomiting oc-
Responder鈩?, Barrier (PE/PA/PE), Tychem脭BR/LV, Tychem脭 SL,
curs have casualty lean forward with head down to avoid breathing in
Tychem脭TK gauntlet gloves. Other impervious protective
of vomitus. If breathing has stopped give artificial respiration. If breath-
body-covering clothing, such as apron, sleeves, trousers, coveralls,
ing and pulse are absent, give CPR. Use mouth guards to prevent
boots, sufficient to prevent any contact.
contact.
Other Personal Protective Equipment: Safety shower and
Note to physician: After initial decontamination with copious
eye-wash fountain in work area.
amounts of water, polyethylene glycol/alcohol (2:1) may be used to re-
Leak and Spill Procedure: Stop or reduce discharge if it can be
move phenol from skin (do not use in eyes). Determination of urinary
done safely. Evacuate area. Ventilate area. Eliminate all sources of
ignition. Ground and bond all equipment. Cleanup personnel must be phenols may help in establishing extent of exposure. If lavage is per-
thoroughly trained in the hazards of this material, and must wear pro- formed, suggest endotracheal and/or esophagoscopic control.
tective equipment and clothing sufficient to prevent inhalation of
vapours or mists (see 鈥淩espiratory Protection鈥?) and contact with skin, REFERENCES USED
eyes or clothing. Contain material with inert non-combustible absor- CCINFO disc: Cheminfo
bent. Prevent entry into water or sewer systems. Collect
Online NIOSH Pocket Guide to Chemical Hazards
contaminated absorbent and put in covered containers for collection
Budavari: The Merck Index, 12th ed., 1997
by approved disposal agency. Contaminated absorbent poses the
same hazards as the product; treat with extreme caution. Flush area Royal Society of Chemistry: Chemical Safety Data Sheets, Vol. 4b, 1991
of spill thoroughly with copious amounts of running water. Sax, Lewis: Hawley鈥檚 Condensed Chemical Dictionary, 11th ed., 1987
Waste Disposal: Follow all federal, provincial and local regulations Suppliers鈥? Material Safety Data Sheets
for disposal.
Handling Procedures and Equipment: CORROSIVE, VERY ADDITIONAL INFORMATION
TOXIC. Personnel working with this chemical must be thoroughly
trained in its hazards, and its safe use, must wear appropriate protec- Date Issued: June 15, 1989
tive equipment and clothing, in an area with proper ventilation and Revision: April 2008
engineering controls. DO NOT WORK ALONE. Use the smallest
MSDS: 6910-5, 6920-5
amount possible for the purpose, in designated areas with adequate
Proposed WHMIS Classification: B3; D1A; D2A; E
ventilation. Keep away from heat, flame hot surfaces, all sources of
ignition, and all incompatiblae materials. Ground and bond all equip-
ment to prevent static charge accumulation. Use non-sparking tools. Prepared by: Caledon Laboratories Ltd. (905) 877-0101
Post 鈥淣o Smoking鈥? signs. Avoid all inhalation and contact with skin, Caledon Laboratories Ltd. believes the information contained herein is
eyes, and clothing. Avoid procedures which generate dust or mist. reliable and accurate. Caledon makes no warranty with respect thereto
Empty containers contain hazardous residues; treat with caution. and expressly disclaims all liability for reliance thereon. Such information
Storage Requirements: Store in glass containers in a cool, dry, is solely for your consideration, investigation, and verification.
well-ventilated area out of direct sunlight and away from heat, flame,
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