MATERIAL SAFETY DATA SHEET SSPE BUFFER
PRODUCT CODE NUMBER(S): 8470-5
PRODUCT IDENTIFICATION Reactivity: Avoid excessive heat, generation of mist, all in-
compatible materials.
Chemical Name and Synonyms: SSPE Buffer concen- Hazardous Decomposition Products: COx , NOx
trate
Chemical Family: Mixture
FIRE AND EXPLOSION DATA
Chemical Formula: Mixture
Flammability: Not combustible
Product Use: Laboratory reagent
Extinguishing Media: Use extinguishing media
Manufacturer鈥檚 Name and Address:
pappropriate to the surrounding fire. Water spray can be
Caledon Laboratories Ltd. used to cool containers, flush chemical away from fire. Fight
40 Armstrong Avenue fire from upwind, from a safe distance. Firefighters must
Georgetown, Ontario L7G 4R9 wear protective equipment and clothing sufficient to prevent
inhalation of mist or fumes, and contact with skin and eyes.
Telephone No: (905) 877-0101
Flash Point (Method Used): Not applicable
Fax No: (905) 877-6666
Autoignition Temperature: Not applicable
Emergency Telephone No: CANUTEC (613) 996-6666
Upper Flammable Limit (% by volume): Not applicable
HAZARDOUS INGREDIENTS OF MATERIALS Lower Flammable Limit (% by volume): Not applicable
Hazardous Combustion Products: COx, NOx, irritating
Ingredients % TLV Units CAS No. smoke
Sodium phosphate, N/A Not established 7782-85-6 Sensitivity to Impact: None identified
dibasic, heptahydrate Sensitivity to Static discharge: None identified
Sodium chloride N/A Not established 7647-14-5
TOXICOLOGICAL PROPERTIES AND HEALTH DATA
Ethylenediamine
tetraacetic acid N/A Not established 6381-92-6 Toxicological Data:
PHYSICAL DATA LD50: (oral, rat) 3 g/kg (NaCl); (oral, rat) 12,930 mg/kg
(Na2HPO4.7H2O)
Physical State: Liquid LC50: Not available
Odour and Appearance: Colourless liquid Irritation: (eye, rabbit) 500 mg/24h, mild;
Odour Threshold (ppm): Not available (skin, rabbit) 500 mg/24h, mild (Na2HPO4.7H2O)
Vapour Pressure (mm Hg): Not available
Effects of Acute Exposure to Product:
Vapour Density (Air = 1): Not applicable
Evaporation Rate: Not applicable Inhaled: Essentially non-toxic. May cause irritation to nose
throat and upper respiratory tract.
Boiling Point (degrees C): Not available
In contact with skin: May cause mild irritation.
Melting Point (degrees C): Not available
In contact with eyes: May cause mild irritation with tem-
pH: Not available
porary redness, itching, tearing, pain.
Specific Gravity: Not available
Ingested: Essentially non-toxic. May cause mild gastroin-
Coefficient of Water/Oil distribution: Not available testinal irritation. Large doses may cause nausea and
vomiting and exert a mild diuretic or laxative effect producing
SHIPPING DESCRIPTION diarrhea. In addition, severe overdosages of sodium salts
may cause hypernoia and convulsing.
UN: Not regulated
T.D.G. Class: Not regulated Effects of Chronic Exposure to Product:
Pkg. Group: Not regulated
Sodium chloride presents no serious health effects in normal
industrial usage. However, sodium chloride is linked to
REACTIVITY DATA
heart and blood pressure problems through dietary intake.
Chemical Stability: Stable under normal temperatures and Persons afflicted with blood pressure or heart problems
pressures may be sensitized to workplace exposures.
Incompatibility with other substances: May react vigor- Dermatitis may develop from repeated or prolonged skin ex-
ously with bases, oxidizing agents, acids. Attacks copper,
posure to sodium phosphate. Long term ingestion of >1%
brass, aluminum, but not steel or iron. Aluminum reacts with
sodium phosphate in diet caused kidney damage in rats; no
aqueous solutions of EDTA to release hydrogen.
effects were observed after administration of 0.5% of diet
over a three-year period.
SSPE BUFFER
MSDS
CODE: 8470-5
Carcinogenicity: No information available or if a large amount has been ingested, get medical
attention.
Teratogenicity: No information available
Reproductive Effects: No information available
REFERENCES USED
Mutagenicity: No information available
CINFO disc: Cheminfo
Synergistic Products: Not known
Budavari: The Merck Index, 12th ed., 1997
PREVENTIVE MEASURES Royal Society of Chemistry: Chemical Safety Data Sheets,
Vol. 2, 1989
Engineering Controls: Local exhaust ventilation recom-
Sax, Lewis: Hawley鈥檚 Condensed Chemical Dictionary, 11th
mended.
ed., 1987
Respiratory Protection: Dust/mist mask. For conditions
Sax: Dangerous Properties of Industrial Materials, 5th ed.,
where dust or mist is present, to the maximum use specified
by the respirator supplier, NIOSH/OSHA approved half- face 1979
high-efficiency dust/mist filter respirator, or NIOSH/OSHA Suppliers鈥? Material Safety Data Sheets
approved full face-piece high-efficiency dust/mist filter respi-
rator. Higher or unknown concentrations, or for fire or spill
ADDITIONAL INFORMATION
conditions, self-contained breathing apparatus, or full
face-piece, positive-pressure supplied-air respirator. Date Issued: May 6, 1999
Eye Protection: Chemical safety glasses. Do not wear Revision: May 2008
contact lenses when working with chemicals.
MSDS: 8470-5
Skin Protection: Wear protective gloves and clean
Proposed WHMIS Designation: Not controlled. Not re-
body-covering clothing, long-sleeved shirt, trousers, apron
quired to be updated every three years (WHMIS 1992, B-40,
or lab coat.
Section 29,2)
Other Personal Protective Equipment: Eyewash fountain
ans safety shower in work area.
Prepared by: Caledon Laboratories Ltd. (905) 877-0101
Leak and Spill Procedure: Ventilate area. Cleanup per-
Caledon Laboratories Ltd. believes the information contained
sonnel should be thoroughly trained in the hazards of this
herein is reliable and accurate. Caledon makes no warranty
material and should wear protective equipment and clothing
with respect thereto and expressly disclaims all liability for reli-
sufficient to prevent inhalation and contact with skin and
ance thereon. Such information is solely for your consider-
eyes. Prevent from entering sewers or waterways. Mix with
sand or inert absorbent, collect and transfer carefully into la- ation, investigation, and verification.
belled, covered container(s) for removal by disposal
company. Wash site of spillage thoroughly with water and
detergent.
Waste Disposal: Follow all federal, provincial and local
regulations for disposal.
Handling Procedures and Equipment: Workers using this
chemical must be properly trained in its hazards and its safe
use, and must wear appropriate protective equipment and
clothing. Follow routine safe handling procedures and good
housekeeping procedures. Avoid generating mist. Avoid in-
halation and contact with skin and eyes. Use the smallest
amount possible for the purpose, in designated areas with
adequate ventilation. Keep containers closed when not in
use and when empty. Wash thoroughly after handling.
Storage Requirements: Store in suitable, labelled contain-
ers, in a cool, dry, well-ventilated area, out of direct sunlight.
Store away from incompatible materials. Keep containers
tightly closed when not in use and when empty. Protect
from damage, and inspect frequently for signs of leaking.
FIRST AID MEASURES
Specific Measures:
Eyes: Flush eyes thoroughly with running water for five to
ten (5-10) minutes, or until no trace of chemical remains,
holding eyelids open while flushing. Get medical advice if ir-
ritation persists.
Skin: Flush skin thoroughly with running water until no
trace of chemical remains. Get medical attention if irritation
develops.
Inhalation: Remove to fresh air. Give oxygen and get
medical attention for breathing difficulty.
Ingestion: If victim is alert and not convulsing, give 2 to 4
glasses of water to dilute material. If vomiting occurs, rinse
mouth and give more water to drink. If victim feels unwell,
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