MATERIAL SAFETY DATA SHEET 1-PROPANOL
PRODUCT CODE NUMBER(S): 8500-1, 8501-2, 8501-7
PRODUCT IDENTIFICATION is corrosive to aluminum above 38掳C. May attack some
forms of plastics, rubber, coatings.
Chemical Name and Synonyms: 1-Propanol; n-Propyl al- Reactivity: Avoid high temperatures, sparks, open flames,
cohol; Propylic alcohol; Ethyl-carbinol all sources of ignition, all incompatible materials, generation
Chemical Family: Primary aliphatic alcohol of mist or vapour.
Chemical Formula: CH3CH2CH2OH Hazardous Decomposition Products: CO2 and CO
Product Use: Laboratory solvent
FIRE AND EXPLOSION DATA
Manufacturer鈥檚 Name and Address:
Caledon Laboratories Ltd. Flammability: Flammable liquid and vapour. Vapour is
40 Armstrong Avenue heavier than air and may travel considerable distance to
Georgetown, Ontario L7G 4R9 source of ignition and flash back. Vapours form explosive
mixtures with air, at, or above 15掳C. Closed containers can
Telephone No: (905) 877-0101
rupture violently when heated.
Fax No: (905) 877-6666
Extinguishing Media: CO2, dry chemical powder, alco-
Emergency Telephone No: CANUTEC (613) 996-6666 hol-resistant foam. Water spray or fog may be used to cool
containers, disperse vapours, and flush material away from
HAZARDOUS INGREDIENTS OF MATERIALS fire, but will be ineffective for fighting fire. Fight fire from up-
wind, from a safe distance. Firefighters must wear protective
Ingredients % TLV Units CAS No. equipment (NIOSH/MSHA approved positive-pressure, full
face-piece self-contained breathing apparatus) and encap-
n-Propyl alcohol 99 200 ppm 71-23-8
sulating chemical splash suit to prevent any inhalation or
(includes skin expo-sure)
contact with this chemical. Closed containers may rupture vi-
olently during fire; withdraw immediately in case of rising
PHYSICAL DATA sound from vent or discoloration of tank.
Flash Point (Method Used): 15掳C (CC)
Physical State: Liquid
Autoignition Temperature: Reported values vary widely,
Odour and Appearance: Clear, colourless, mobile liquid
371 to 440掳C
with mild alcoholic odour
Upper Flammable Limit (% by volume): 13.7
Odour Threshold (ppm): Varies widely, 0.031 to 41 ppm
(detection); 0.081 to 61 ppm (recognition). Good warning Lower Flammable Limit (% by volume): 2.2
properties, TLV well above odour threshold.
Hazardous Combustion Products: CO2, CO
Vapour Pressure (mm Hg): 15 mm Hg at 20掳C
Sensitivity to Impact: None identified
Vapour Density (Air = 1): 2.07 at 20掳C
Sensitivity to Static discharge: Mixtures of vapour and air
Evaporation Rate (n-bu ac) = 1: 1.3 at concentrations in the flammable range may be ignited by
Boiling Point (掳C): 97.2掳C static discharge. Liquid has high electrical conductivity and
will probably not accumulate static charge.
Freezing Point (掳C): -126.6掳C
pH: Not available
TOXICOLOGICAL PROPERTIES AND HEALTH DATA
Specific Gravity: 0.804 at 20掳C
Coefficient of Water/Oil distribution: LogP(oct)=0.25 Toxicological Data:
LD50: (oral, rat) 1,870 mg/kg; (oral, young male rat): 560
SHIPPING DESCRIPTION mg/kg; (dermal, rabbit) 4,000 mg/kg
LC50: (rat) 4,000 ppm/4h (2/6 died)
UN: 1274
T.D.G. Class: 3
Effects of Acute Exposure to Product:
Pkg. Group: II
Inhaled: No reports of harmful effects from occupational
REACTIVITY DATA exposure. Based on animal information, and information
about related alcohols, exposure to high vapour concentra-
Chemical Stability: Normally stable. tions may cause respiratory tract irritation, headache,
Incompatibility with other substances: Increased risk of dizziness, nausea, incoordination, drowsiness and eventual
fire and explosion with strong oxidizing agents. Vigorous or loss of consciousness and death.
violent reaction with strong acids, acid chlorides, acid anhy- In contact with skin: No reports of irritation or toxic effects
drides, halogens and halogen compounds. Gives off in human and animal testing. May be absorbed through skin,
flammable hydrogen gas with alkali or alkali earth metals. but is unlikely to cause harmful effects by skin absorption.
Mixtures with potassium tert-butoxide may ignite. May react In contact with eyes: May cause severe irritation, conjunc-
explosively with barium perchlorate, chlorine, hypochlorous tivitis, corneal burns, based on animal testing. No human
acid, ethylene oxide, permonosulphuric acid, or tri-isobutyl information available.
aluminum. Not corrosive to metals at normal termperatures;
1-PROPANOL
MSDS
CODE: 8500-1, 8501-2, 8501-7
Ingested: May cause irritation and burning of the mouth accumulation. Use non-sparking tools. Avoid splash filling.
and throat, nausea, dizziness, abdominal pain, and CNS de- Keep storage and work areas free of combustible or incompati-
pression. A normal component of food and alcoholic ble materials. Use the smallest amount possible for the
beverages; ingestion is not a normal route of occupational purpose, in a designated area with adequate ventilation. Avoid
exposure. Aspiration during ingestion or vomiting can result contact with skin and eyes and inhalation of vapours. Avoid
in severe life-threatening lung damage, chemical pneumoni- generating vapours or mists. Empty containers may contain
tis, or pulmonary edema. hazardous residues; treat with extreme caution.
Storage Requirements: Store in suitable, labelled containers,
Effects of Chronic Exposure to Product: in a cool, dry, well-ventilated area, out of direct sunlight and
away from all sources of heat and ignition, and incompatible
Prolonged and repeated contact may lead to dermatitis.
materials. Keep tightly closed when not in use. Protect from
There are no reports of other health effects from long-term damage. Inspect regularly for signs of leaking or damage.
exposure. Keep storage area clear of combustible materials. Post 鈥淣O
Carcinogenicity: Carcinogenic to laboratory animals in SMOKING鈥? signs. Have appropriate fire extinguishers and spill
conditions not considered relevant to occupational exposure cleanup equipment near the storage area. Ground and bond
(ACGIH-A3). Not likely to cause cancer to humans except equipment and containers to prevent a static charge buildup.
under unusual conditions. Exposure to A3 carcinogen Storage facilities should be made of fire-resistant materials.
should be kept as low as is possible. Provide raised sills and trenches to drain to a safe area.
Teratogenicity: Has produced effects in animal testing, at
FIRST AID MEASURES
maternally toxic levels. No human information available.
Reproductive Effects: Has produced male effects,
Specific Measures:
inlcuding reduced fertility in animal testing. No human infor-
mation available. Eyes: IMMEDIATELY flush eyes with warm gently running wa-
Mutagenicity: Negative in in vitro mammalian tests. Both ter for at least twenty (20) minutes, holding eyelids open while
positive and negative results in bacterial testing. flushing. Take care not to flush contaminated water into unaf-
Synergistic Products: Alcohols may react synergistically fected eye. Get medical attention immediately.
with chlorinated solvents (e.g. carbon tetrachloride, chloro- Skin: Remove contaminated clothing (including rings, watches,
form) or dithiocarbamates (e.g. disulphiram, thioacetamide) belts and shoes). Immediately flush exposed area with large
amounts of warm running water for five to ten (5-10) minutes.
PREVENTIVE MEASURES If irritation persists, get medical attention.
Inhalation: Remove casualty to fresh air (rescuers must use
Engineering Controls: Non-sparking, grounded, separate,
caution to avoid exposure to contaminating fumes). Give oxy-
exhaust ventilation required.
gen and get medical attention for breathing difficulty.
Respiratory Protection: Up to 800 ppm: NIOSH/MSHA
Ingestion: DO NOT INDUCE VOMITING. Danger of aspiration
approved chemical cartridge respirator equipped with or-
if vomiting occurs. If the casualty is alert and not convulsing,
ganic vapour cartridges, or powered air-purifying respirator
have them drink 2 to 4 glasses of water to dilute the material. If
with organic vapour cartridges, or supplied-air respirator.
spontaneous vomiting occurs, have casualty lean forward to
Higher or unknown concentrations, as in fire or spill condi-
avoid breathing in of emesis. Rinse mouth and administer more
tions: positive-pressure, full face-piece self-contained
water.
breathing apparatus, or positive-pressure, full face-piece
supplied-air respirator with an auxiliary positive-pressure
REFERENCES USED
self-contained breathing apparatus.
Eye Protection: Chemical safety goggles and/or face CCINFO disc: Cheminfo, March 2006
shield.
Budavari: The Merck Index, 12th ed., 1997
Skin Protection: Butyl or nitrile rubber, Viton鈩? gloves.
Sax, Lewis: Hawley鈥檚 Condensed Chemical Dictionary, 11th ed.,
Other protective clothing, coat, coveralls, sleeves, boots,
1987
sufficient to prevent contact
Royal Society of Chemistry: Chemical Safety Data Sheets, Vol. 1,
Other Personal Protective Equipment: Safety shower
1992
and eye bath located close to chemical exposure area.
Leak and Spill Procedure: Evacuate and ventilate area. Suppliers鈥? Material Safety Data Sheets
Eliminate all sources of ignition. Cleanup personnel must be
ADDITIONAL INFORMATION
thoroughly trained in the hazards of this material and must
wear protective equipment and clothing sufficient to prevent
Date Issued: November 1, 1988
inhalation of vapours or mists, and contact with skin, eyes or
clothing. Stop or reduce discharge if safe to do so. Contain Revision: March 2006
spill and collect using inert absorbent material. Do not touch MSDS: 8500-1, 8501-2, 8501-7
spilled material or contaminated absorbent. Prevent from
Proposed WHMIS Designation: B2; D2B (eye irritation)
entering sewers or waterways. Contaminated absorbent
may pose the same hazards as the chemical; treat with cau-
Prepared by: Caledon Laboratories Ltd.(905) 877-0101
tion. Flush area of spill with copious amounts of running
water. Caledon Laboratories Ltd. believes the information contained
herein is reliable and accurate. Caledon makes no warranty with
Waste Disposal: Follow all federal, provincial and local
regulations for disposal. respect thereto and expressly disclaims all liability for reliance
Handling Procedures and Equipment: FLAMMABLE, thereon. Such information is solely for your consideration, investi-
EYE IRRITANT. Before working with this product, ensure gation, and verification.
that engineering controls are operating and that proper pro-
tective clothing and equipment is being used. Workers must
be thoroughly trained in the hazards of this material and its
safe use, and must wear appropriate protective equipment
and clothing suitable for the application. Post 鈥淣o Smoking鈥?
signs. Ground and bond equipment to prevent static charge
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