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MSDS Material Safety Data Sheet
CAS

79561-22-1

File Name: fws_gov---MSDS_8061_LHRHa.asp
LHRHa MSDS                                                                                    Page 1 of 3




MATERIAL SAFETY DATA SHEET

LHRH ANALOGUE



Section I - IDENTIFICATION

PRODUCT: LHRH Analogue

SYNONYMS: Luteinizing Hormone Releasing Hormone, Des-GLY10-D-ALA6-LHRH
ethylamide

CHEMICAL FORMULA: p-Glu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NH-C2H5

CHEMICAL ABSTRACT NO.: 79561-22-1

PRODUCT CODE NO.: 13440



Section II - HAZARDOUS INGREDIENTS
COMPOSITION % TLV HAZARD
LHRH Analogue 97% MIN. N/A Harmful, may cause reproductive
disorders




Section III - HEALTH & FIRST AID INFORMATION

INHALATION: May be harmful. Remove to fresh air; if breathing becomes difficult,
contact a physician.

INGESTION: May be harmful. If swallowed, wash out mouth with copious amounts of
water - if the person is concious. Contact a physician.

EYE CONTACT: May be harmful. In case of contact, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by separating eyelids with fingers.
Contact a physician.



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LHRHa MSDS Page 2 of 3



SKIN CONTACT: May be harmful. In case of contact, flush with copious amounts of
water for at least 15 minutes. Remove contaminated clothing and wash before re-using.
Contact a physician.

OTHER HEALTH INFORMATION: The toxicological properties of sGnRHa have
not been thoroughly investigated. The actions are similar to luteinizing hormone releasing
hormone (LHRH, Gonadotropin releasing hormone, GnRH) in humans. LHRH is the key
mediator in the liberation of the pituitary gonadotropins, luteinizing hormone (LH) and
follicle stimulating hormone (FSH). LHRH may modify reproductive ability by
influencing plasma gonadotropin levels and comcomitantly gonadal steroid levels.



Section IV - PHYSICAL DATA

SOLUBILITY IN WATER: Miscible

APPEARANCE AND COLOUR: White fluffy crystals



Section V - FIRE AND EXPLOSION HAZARDS

SPECIAL FIRE FIGHTING PROCEDURES & PRECAUTIONS: Wear self-
contained breathing apparatus and protective clothing to prevent contact with skin and
eyes.

UNUSUAL FIRE & EXPLOSION HAZARDS: None



Section VI - REACTIVITY

STABILITY: Stable

HAZARDOUS POLYMERIZATION: Will not occur.

CONDITIONS & MATERIALS TO AVOID: Avoid contact with oxidizing materials.

HAZARDOUS DECOMPOSITION PRODUCTS: Carbon monoxide, carbon dioxide
and nitrogen oxides.



Section VII - EMPLOYEE PROTECTION

RESPIRATORY PROTECTION: Wear approved respirator and use mechanical
ventilation if possible.

PROTECTIVE CLOTHING: Wear protective clothing and chemical resistant gloves.



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LHRHa MSDS Page 3 of 3



EYE PROTECTION: Wear tight fitting chemical safety goggles.

SPILL OR LEAK PRECAUTIONS: Wear respirator, gloves, goggles and protective
clothing. Sweep up and collect in a bag for waste disposal. Ventilate area and wash
thoroughly after cleanup is complete.

DISPOSAL: Observe all governmental regulations governing disposal. Dissolve in a
combustible solvent and burn in a chemical incinerator equipped with an afterburner and
scrubber.

Section VIII - REGULATORY CONTROLS

DEPT. OF TRANSPORTATION: None

OTHER REGULATORY REQUIREMENT: None

Section IX - PRECAUTIONS: HANDLING, STORAGE & USAGE

Store refrigerated. Handle with care.



PREPARED BY: MSDS Department DATE: Update January 10, 2002




All material, unless otherwise specified, is copyrighted by Syndel Laboratories Ltd., 1999-2003.


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