Material Safety Data Sheet
Revised 6/01
Section I
Manufacturer's Name Non-Emergency Telephone #
Coatings For Industry, Inc. 215-723-0919
Address Emergency Telephone #
319 Township Line Road 1-800-535-5053
Souderton, PA 18964
Chemical Name & Synonyms Chemical Family
1,6 Hexamethylene Diisocyanate Aliphatic Isocyanate
Based Polyisocyanate
Trade Name & Synonyms
Urethabond 2000 Part B
Section II - Hazardous Ingredients
% TLV CAS #
-------------------------------------------------------------------------------------------------------
Homopolymer of HDI
Essentially 100% ACGIH: Not Established
The manufacturer recommended guideline level for exposure to HDI based
polyisocyanates is:
0.5 mg/m3 TWA over 8 hours &
1.0 mg/m3 stel over 15 minutes
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Hexamethylene
Diisocyanate (HDI) * OSHA: Not Established 822-06-0
ACGIH:.005 ppm TWA
*Residual monomer content less than 0.7% based on resin solids at the time of
manufacture. However, after 3-6 months storage, the free monomer content
may rise to a maximum of 1.6%. Manufacturer recommends a ceiling level of
0.02 ppm.
This document is prepared pursuant to the OSHA Hazard Communication Standard
(29 CFR 1910.1200). In addition, other substances not "hazardous" per this OSHA
standard may be listed.
Page 2 of 9
Section III - Physical Data
Specific Gravity ~~~~~~~~~~~~~~~1.11-1.13 @ 77掳 F. (25掳 C.)
% Volatile by Weight ~~~~~~~~~~ Approx 0.7 to 1.6% (Calculated Data)
Bulk Density ~~~~~~~~~~~~~~~~~ 9.24-9.41 lbs./gallon
Vapor Pressure ~~~~~~~~~~~~~~~ Polyisocyanate: Approx. 4.7 x 10-7 mm hg
@ 20掳 C.
Molecular Weight ~~~~~~~~~~~~~~ Approx. 500 (Polyisocyanate)
Water Solubility ~~~~~~~~~~~~~~~~ Resin is insoluble - reacts slowly with
water to liberate CO2 gas
Appearance & Odor ~~~~~~~~~~~~~ Clear/pale yellow liquid with solvent odor
Section IV - Fire and Explosion Data
Flash point ~~~~~~~~~~~~~~~~~~~ 385.0掳 F. (196.1掳 C.) Setaflash
Extinguishing Media ~~~~~~~~~~~~ Dry chemical; carbon dioxide; foam; water
spray for large fires.
Special Fire Fighting Procedures:
Full emergency equipment with self contained breathing apparatus and full protective clothing
should be worn by fire fighters. During a fire, HDI vapors and other irritating, highly toxic
gases may be generated by thermal decomposition or combustion. (see Section VIII).
Isolate from heat, electrical equipment, sparks and open flame. Closed container may explode
when exposed to extreme heat or burst when contaminated with water (CO2 evolved).
Solvent vapors may be heavier than air. Stagnant air may cause vapors to accumulate and
travel along the ground to an ignition source which may result in a flash back to the source
of the vapors.
Section V - Human Health Data
Route of entry ~~~~~~~~~~~~~~~~ Inhalation; skin contact; eye contact.
Human Effects and Symptoms of Overexposure:
Acute Inhalation:HDI vapors or mist at concentrations above the TLV or MGL can irritate
(burning sensation) the mucous membranes in the respiratory tract (nose, throat, lungs) causing
runny nose, sore throat, coughing, chest discomfort, shortness of breath and reduced lung
function (breathing obstruction). Persons with a preexisting, nonspecific bronchial
hyperreactivity can respond to concentrations below the TLV or the manufacturer's suggested
guideline with similar symptoms as well as an asthma attack. Exposure well above the TLV or
manufacturer's suggested guideline may lead to bronchitis, bronchial spasm and pulmonary
edema (fluid in lungs). These effects are usually reversible. Chemical or hypersensitive
pneumonitis, with flu-like symptoms (e.g., fever, chills) has also been reported.
Chronic Inhalation:As a result of previous repeated overexposures or a single large dose,
certain individuals will develop isocyanate sensitization (chemical asthma) which will cause
them to react to a later exposure to isocyanate at levels well below the TLV or manufacturer's
suggested guideline.
Page 3 of 9
Section V - Human Health Data (cont.)
These symptoms, which include: chest tightness, wheezing, cough, shortness of breath or
asthmatic attack, could be immediate or delayed up to several hours after exposure. Similar
to many non-specific asthmatic responses, there are reports that once sensitized an individual
can experience these symptoms upon exposure to dust, cold air or other irritants. This
increased lung sensitivity can persist for weeks and in severe cases for several years. Chronic
overexposure to isocyanate has also been reported to cause lung damage, including decrease
in lung function, which may be permanent. Sensitization may be either temporary or
permanent.
Acute Skin Contact:Isocyanates react with skin protein and moisture and can cause irritation.
Symptoms of skin irritation may be reddening, swelling, rash, scaling or blistering. Some
persons may develop skin sensitization from skin contact. Cured material is difficult to
remove. .
Chronic Skin Contact:Prolonged contact with the isocyanate can cause reddening, swelling,
rash, scaling or blistering. In those who have developed a skin sensitization, these symptoms can
develop as a result of contact with very small amounts of liquid material or even as a result of
vapor only exposure. .
Acute Eye Contact:Liquid, aerosols and vapors of this product are irritating and can cause
tearing, reddening and swelling accompanied by a stinging sensation and/or feeling like that of
fine dust in the eyes.
Chronic Eye Contact:May result in corneal opacity (clouding of the eye surface).
Acute Ingestion:Can result in irritation and possible corrosive action in the mouth, stomach
tissue and digestive tract.
Chronic Ingestion:None found
Carcinogenicity
NTP ~~~~~~~~~~~~~~~~~ Not Listed
IARC ~~~~~~~~~~~~~~~~ Not Listed
OSHA ~~~~~~~~~~~~~~~~Not Regulated
Medical Conditions Aggravated by Exposure:Asthma and other respiratory disorders
(bronchitis, emphysema, hyperreactivity), skin allergies, eczema.
Exposure Limits:Not established for product as a whole. Refer to Section II for exposure limits
of hazardous constituents. The manufacturer suggested guidelines of 0.5 mg/m3 TWA and 1.0
mg/m3 stel for the homopolymer of HDI and 0.02 ppm ceiling for HDI monomer are guides
based on limited data; provided pending the review of future data.
Section VI - Emergency and First Aid Procedures
First Aid for Eyes:
Flush with clean, lukewarm water (low pressure) for at least 15 minutes, while lifting eyelids.
Refer individual to physician or opthalmologist for immediate follow up.
First Aid for Skin:
Remove contaminated clothing immediately. Wash affected areas thoroughly with soap and
water. Wash contaminated clothing thoroughly before reuse. For severe exposures, get
under safety shower after removing clothing, then get medical attention. For lesser exposures,
seek medical attention if irritation develops or persists.
First Aid for Inhalation:
Move to an area free from risk of further exposure. Administer oxygen or artificial respiration
as needed. Obtain medical attention. Asthmatic type symptoms may develop and may be
immediate or delayed up to several hours. Treatment is essentially symptomatic. Consult
physician.
Page 4 of 9
Section VI - Emergency and First Aid Procedures (cont.)
First Aid for Ingestion:
Do not induce vomiting. Give 1 to 2 cups of milk or water to drink. Do not give anything
by mouth to an unconscious or convulsing person. Consult physician.
Note to Physician.........
Eyes: Stain for evidence of corneal injury. If cornea is burned, instill antibiotic/steriod
preparation frequently. Workplace vapors could produce reversible corneal epithelial edema
impairing vision.
Skin: This product is a known skin sensitizer. Treat symptomatically as for contact
dermatitis or thermal burn.
Ingestion: Treat symptomatically. There is no specific antidote. Inducing vomiting is
contraindicated because of the irritating nature of the product.
Inhalation: This product is a known pulmonary sensitizer. Treatment is essentially
symptomatic. An individual having a dermal or pulmonary sensitization reaction to this
material must be removed from any further exposure to any isocyanate.
Section VII - Employee Protection Recommendations
Required work/hygiene procedures:
Precautions must be taken so that persons handling product do not breathe the vapors or
have it contact the eyes or skin. In spray operations, protection must be afforded against
exposure to both vapor and spray mist.
Eye protection requirements:
Safety glasses, splash goggles or face shield. Contact lenses should not be worn.
Skin protection requirements:
Permeation resistant gloves. Cover as much of the exposed skin area as possible with
appropriate clothing. If skin creams are used, keep the area protected only by the cream to
a minimum.
Respirator requirements:
A respirator that is recommended or approved for use in isocyanate containing
environments (air purifying or fresh air supplied) may be necessary. Consider type of
application and environmental concentrations. Observe OSHA regulations for respirator use
(29CFR1910.134).
Note on Odor Warning Properties: Pure isocyanate materials have odor thresholds that
are higher than the TLV, PEL or manufacturer's suggested guidelines. Thus, if a
vapor/particulate air-purifying respirator has exceeded its service life, breakthrough of the
filter can result in exposure over the allowable limit without the wearer being able to smell the
isocyanate.
Page 5 of 9
Section VII - Employee Protection Recommendations (cont.)
Spray Application:
Good industrial hygiene practice dictates that when isocyanate based coatings are spray
applied, some form of respiratory protection should be worn. During the spray application of
coatings containing this product, the use of a supplied air (either positive pressure or continuous
flow type) respirator is mandatory when ONE OR MORE of the following conditions exist:
~ the airborne isocyanate concentrations are not known; or
~ the airborne HDI monomer concentrations exceed 0.05 ppm averaged over eight (8) hours (10
times the 8 hour TWA exposure limit); or
~ the polyisocyanate (polymeric, oligomeric) concentrations exceed 5 mg/m3 averaged over
8 hours or 10 mg/m3 averaged over 15 minutes (10 times the 8 hour TWA or the 15 minute
STEL exposure limits); or
~ spraying is performed in a confined space or in an area with limited ventilation.(See OSHA
Confined Space Standard CFR 1910.146).
A properly fitted air purifying (combination organic vapor and particulate) respirator, proven
by test to be effective in isocyanate-containing spray paint environments, and used in accordance
with all recommendations made by the manufacturer, can be used when ALL of the following
conditions are met:
~ the airborne HDI monomer concentrations is known to be below 0.05 ppm averaged over eight
(8) hours (10 times the 8 hour TWA exposure limit)
~ the polyisocyanate (polymeric, oligomeric) concentrations are known to be below 5 mg/m3
averaged over 8 hours or 10 mg/m3 averaged over 15 minutes (10 times the 8 hour TWA or the
15 minute STEL exposure limits).
~a NIOSH certified End of Service Life Indicator or a change schedule based upon objective
information or data is used to ensure that cartridges are replaced before the end of their service
life. In addition, prefilters should be changed whenever breathing resistance increases due to
particulate buildup.
Non-spray Operations:
Even during non-spray operations such as mixing, batch making, brush or roller application,
etc., depending on the conditions (for example, heating of material or application to a hot
substrate), it is possible to be exposed to airborne isocyanate vapors. Therefore, when the
coatings system contains solvents and will be applied in a non-spray manner, a positive
pressure supplied air respirator must be worn when ONE OR MORE of the following conditions
exist:
~ the airborne concentrations are unknown; or
~ the airborne HDI monomer concentrations exceed 0.05 ppm averaged over eight (8) hours (10
times the 8 hour TWA exposure limit); or
~ the airborne concentrations of the polyisocyanate (polymeric, oligomeric) exceed 5 mg/m3
averaged over 8 hours or 10 mg/m3 averaged over 15 minutes (10 times the 8 hour TWA or the
15 minute STEL exposure limits); or
~ operations are performed in a confined space or in an area with limited ventilation.(See OSHA
Confined Space Standard CFR 1910.146)
A properly fitted air purifying (combination organic vapor and particulate) respirator, proven
by test to be effective in isocyanate-containing spray paint environments, and used in accordance
with all recommendations made by the manufacturer, can be used when ALL of the following
conditions are met:
~ the airborne concentrations of the HDI monomer are below 0.05 ppm averaged over eight (8)
hours (10 times the 8 hour TWA exposure limit); and
~ the polyisocyanate (polymeric, oligomeric) concentrations are known to be below 5 mg/m3
averaged over 8 hours or 10 mg/m3 averaged over 15 minutes (10 times the 8 hour TWA or the
15 minute STEL exposure limits); and
Page 6 of 9
Section VII - Employee Protection Recommendations (cont.)
~a NIOSH certified End of Service Life Indicator or a change schedule based upon objective
information or data is used to ensure that cartridges are replaced before the end of their service
life. In addition, prefilters should be changed whenever breathing resistance increases due to
particulate buildup.
Ventilation Requirements:
Exhaust ventilation sufficient to keep the airborne concentrations of HDI and polyisocyanate
below their respective TLV and manufacturer's suggested guidelines must be utilized.
Exhaust air may need to be cleaned by scrubber or filters to reduce environmental
contamination.
Monitoring:
Refer to Patty's Industrial Hygiene and Toxicology- Volume 1 (3rd edition) Chapter 17
and Volume III (1st edition) Chapter 3- for guidance concerning appropriate air sampling
strategy to determine airborne concentrations.
Medical Surveillance:
Medical supervision of all employees who handle or come in contact with HDI is
recommended. This should include preemployment and periodic medical examinations with
respiratory function tests (FEV, FVC as a minimum). Persons with asthmatic-type conditions,
chronic bronchitis, other chronic respiratory diseases or recurrent skin eczema or sensitization
should be excluded from working with isocyanates. Once a person is diagnosed as being
sensitized to isocyanates, no further exposure can be permitted.
Additional Protective Measures:
Safety showers and eyewash stations should be available. Educate and train employees in
safe use of product. Follow all label information.
Section VIII - Reactivity Data
Stability ~~~~~~~~~~~~~~~~~~~~~ Stable under normal conditions.
Hazardous Polymerization:
May occur; contact with moisture or other materials which react with isocyanates or
temperatures over 400掳 F. (204掳 C) may cause polymerization.
Incompatibilities ~~~~~~~~~~~~~~~ Water, amines, strong bases, alcohols, metal
compounds and surface active materials.
Instability Conditions ~~~~~~~~~~~~ None Known.
Decomposition Products ~~~~~~~~~~ By heat and fires : carbon dioxide, oxides of nitrogen,
HCN, HDI and other undetermined aliphatic fragments.
Section IX - Spill and Leak Procedures
Spill or leak procedures:
Evacuate nonessential personnel. Remove all sources of ignition and ventilate the area.
Notify appropriate authorities if necessary. Put on personal protective equipment
(see Section VII). Dike or impound spilled material and control further spillage if feasible.
Cover the spill with sawdust, vermiculite, fuller's earth or other absorbent material. Pour
decontamination solution over spill area and allow to react for at least 10 minutes. Collect
material in open containers and add further amounts of decontamination solution. Remove
containers to a safe place, cover loosely, allow to stand for 24 to 48 hours. Wash down
spill area with decontamination solutions.
Decontamination Solutions:
Nonionic surfactant union carbide's tergitol TMN-10 (20%) and water (80%);
concentrated ammonia (3-8%), detergent (2%) and water (90-95%).
Page 7 of 9
Section IX - Spill and Leak Procedures (cont.)
Waste disposal method:
Waste must be disposed of in accordance with federal, state, and local environmental control
regulations. Incineration is the preferred method. Empty containers must be handled with
care due to product residue and flammable solvent vapor. Decontaminate containers prior
to disposal. Do not heat or cut empty container with electric or gas torch.
(see Sections IV and VIII).
Section X - Special Precautions and Storage Data
Storage Temperature (min/max)~~~~ 30掳 F. (-34掳 C)/122掳 F. (50掳 C)
Shelf Life ~~~~~~~~~~~~~~~~~~~~ One year, if unopened
Special Sensitivity:
If container is exposed to high heat, it can be pressurized and possibly rupture explosively.
HDI reacts slowly with water to form CO2 gas. This gas can cause sealed containers to
expand and possibly rupture explosively.
Handling/Storage Precautions:
Store in tightly closed containers to prevent moisture contamination. Do not
reseal if contamination is suspected. At maximum storage temperatures noted, material may
slowly polymerize without hazard. Ideal storage temperature range for ease of handling is
50-81掳 F. (10-27掳 C.). Avoid contact with skin and eyes. Employee education and
training in the safe use and handling of this product are required under the OSHA Hazard
Communication Standard.
Section XI - Shipping Information
D.O.T. Shipping Name ~~~~~~~~~~~~ Paint
Technical Shipping Name ~~~~~~~~~~ Polyisocyanate
D.O.T. Hazard Class ~~~~~~~~~~~~~ Not Regulated
UN/NA Number ~~~~~~~~~~~~~~~~~None
Product RQ (lbs.) ~~~~~~~~~~~~~~~~None
Hazard Label ~~~~~~~~~~~~~~~~~~~ None
Hazard Placard ~~~~~~~~~~~~~~~~~ Combustible
Freight Class Package ~~~~~~~~~~~~~Chemicals, NOI (Isocyanate), NMFC 60000
Product Label~~~~~~~~~~~~~~~~~~~Urethabond 2000 Part B
Section XII - Animal Toxicity Data
Toxicity Data For: HDI homopolymer materials except where indicated.
Acute Toxicity
Oral LD50: Estimated to be greater than 10000 mg/kg (rats). (Based on the results of
actual tests conducted using specific HDI-homopolymer products).
Inhalation LC50: Lower respiratory (pulmonary) irritant. LC50 values ranging from
137-1150 mg/m3 were obtained in rats exposed to aerosols.
Eye effects: Severe irritant capable of inducing corneal injury (rabbit); maximum primary
eye irritation score: 54.6/110 for a 24 hour exposure.
Skin effects: Moderate irritant; primary dermal irritation score: 3.4/8.0 (rabbit).
Sensitization: Pulmonary and dermal sensitizer in animals and humans. Evidence exists that
cross-sensitization between HDI and other isocyanates, particularly hydrogenated MDI and
TDI, can occur.
Other Acute Effects: Ames Test: negative for 100% solids HDI homopolymer.
Page 8 of 9
Section XII - Animal Toxicity Data (cont.)
Subchronic Toxicity:
Rats exposed to an HDI homopolymer (biuret type), at 3.7, 17.5 and 76.6 mg/m3 for three
weeks (6 hours/day, 5 days/week) exhibited respiratory distress and inflamed areas of tissue
in the lungs and upper respiratory tract when exposed to 17.5 mg/m3 and above. The No
Observable Effect Level (NOEL) was 3.7 mg/m3. Rats exposed for three months
(6 hours/day, 5 days/week) to an HDI homopolymer (biuret type), at aerosol concentrations
of 0.4, 3.4 and 21 mg/m3 exhibited lung weight increases at the highest dose. Histopathologic
diagnosis of the test animals revealed swelling and thickening in the lower respiratory tract as
well as thickening of the bronchio-alveolar areas of the lung and thickening of the septum in
the 21 mg/m3 animals. There were no effects noted in the upper and central respiratory tract.
The No Observable Effect Level (NOEL) in this study is considered to be 3.4 mg/m3.
Other Toxicity Data:
Mice were exposed to a liquid aerosol of an HDI homopolymer (isocyanate type), mixed with
acetone for three hours. The irritation potential expressed as the RD50 (the concentration
which is predicted to reduce the respiratory rate by 50%) was 20.8 mg/m3 (95% confidence
intervel = 18.3 to 23.9 mg/m3). Pulmonary (lung) irritation was observed first, followed by
sensory (eye, nose throat) irritation.
Section XII - Federal Regulatory Information
OSHA Status ~~~~~~~~~~This product is hazardous under the criteria of the federal OSHA
Hazard Comminucation Standard 29 CFR 1910.1200.
Tsca Status ~~~~~~~~~~~~On TSCA Inventory
Cercla Reportable Quantity~Hexamethylene-1,6-Diisocyanate (CAS# 822-06-0) = 100 lbs.
Sara Title III
Section 302 Extremely Hazardous Substances ~~~~ None
Section 311/312 Hazard Categories ~~~~~~~~~~~Immediate Health Hazard
~~~~~~~~~~~ Delayed Health Hazard
~~~~~~~~~~~ Reactive Hazard
Section 313 Toxic Chemicals ~Hexamethylene-1,6-Diisocyanate (CAS# 822-06-0), 0.70 to
1.6%
RCRA Status ~~~~~~~~~~~~~~~~~~~~~~~~~~~~When discarded in its purchased form,
this product would not be a hazardous waste
either by listing or by characteristic.
However, under RCRA, it is the
responsibility of the product user to
determine at the time of disposal, whether a
material containing the product or derived
from the product should be classified as a
hazardous waste. (40 CFR 261.20-24)
Page 9 of 9
Section XIV - Other Regulatory Information
The following chemicals are specifically listed by individual states; other product specific
health and safety data in other sections of the MSDS may also be applicable for state
requirements. For details on your regulatory requirements, you should contact the
appropriate agency in your state.
Component Name
/CAS Number Concentration State Code
----------------------------------------------------------------------------------------------------
Homopolymer of HDI Essentially 100% PA3, NJ4
28182-81-2
Hexamethylene Diisocyanate (HDI)
822-06-0 * CN2
MA = Massachusetts Hazardous Substance List
NJ1 = New Jersey Hazardous Substance List
NJ4 = New Jersey Other - Included in Predominant Ingredients > 1%
PA1 = Pennsylvania Hazardous Substance List
PA3 = Pennsylvania Non-Hazardous Present at 3% or Greater
CN2 = Canada WHMIS Ingredient Disclosure List over 0.1%
California Proposition 65
To the best of our knowledge, this product contains no levels of listed substances, which the
state of California has found to cause cancer, birth defects or other reproductive effects.
Massachusetts Substance List (MSL)
Hazardous Substances and Extraordinarily Hazardous Substances on the MSL must be identified
when present in products. To the best of our knowledge, this product contains no substances at a
level which could require reporting under the statute.
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Notice: This information is presented in good faith and believed to be accurate as of the
effective date below. However, no warranty is express or implied regarding the accuracy of
this data or the results to be obtained from the use thereof. Coatings For Industry, Inc.
assumes no responsibility for personal injury or property damage to vendees, users or third
parties caused by the material, such vendees or users assume all risks associated with the use
of the material. Regulatory requirements are subject to change and may differ from one
location to another; it is the buyer's responsibility to ensure that its activities comply with
federal, state and local laws. The preceding specific information is made for the purpose of
complying with numerous federal, state and local laws and regulations.
6/01
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