Page 1 of 9
**********************************************************************
MATERIAL SAFETY DATA SHEET
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
**********************************************************************
DATE PREPARED: 3/24/2000
REVISION: 2
**********************************************************************
1. IDENTIFICATION:
PRODUCT NAME: vW FACTOR ELISA KIT
PRODUCT NO: 5290
=====================================================================
2. INGREDIENTS (THE ABOVE KIT CONTAINS THE FOLLOWING ITEMS):
PRODUCT NUMBER PRODUCT IDENTIFICATION (LABEL NAME) COMMENTS
551679 SUBSTRATE SOLUTION
HAZARDOUS INGREDIENT CAS # %
SUBSTRATE SOLUTION MIXTURE 100 MSDS ATTACHED
551677 STOPPING SOLUTION
HAZARDOUS INGREDIENT CAS # %
STOPPING SOLUTION MIXTURE 100 MSDS ATTACHED
551654 ELISA REFERENCE PLASMA
HAZARDOUS INGREDIENT CAS # %
HUMAN PLASMA *
551676 PHOSPHATE BUFFERED SALINE NON-HAZARDOUS
551680 SAMPLE DILUENT NON-HAZARDOUS
551681 vWF:Ag MICROWELLS NON-HAZARDOUS
551678 von WILLEBRAND CONJUGATE NON-HAZARDOUS
*PLASMA HAS BEEN TESTED AND SHOWN TO BE NEGATIVE FOR HEPATITIS B
ANTIGEN (HbSAg) AND HIV-1 ANTIBODY; HOWEVER, THE PLASMA SHOULD BE
HANDLED AS IF CAPABLE OF TRANSMITTING INFECTION.
**********************************************************************
MATERIAL SAFETY DATA SHEET
Page 2 of 9
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
**********************************************************************
DATE PREPARED: 12/2/1993
REVISION: 1
**********************************************************************
1. IDENTIFICATION:
NAME: STOP SOLUTION
CHEMICAL FAMILY: ACID
=====================================================================
2. HAZARDOUS INGREDIENTS:
CHEMICAL NAME/COMMON NAME EXPOSURE LIMITS
CAS# % OSHA PEL ACGIH TLV NIOSH
SULFURIC ACID TWA TWA STEL TWA
1 mg/m3 1 mg/m3 3 mg/m3 1 mg/m3
7664-93-9 < 15
=====================================================================
3. PHYSICAL DATA:
BOILING POINT: NOT AVAILABLE SPECIFIC GRAVITY (H2O = 1):
NOT AVAILABLE
VAPOR PRESSURE (MM HG.): MELTING POINT: N/A
NOT AVAILABLE
VAPOR DENSITY (AIR = 1): NOT AVAILABLE
EVAPORATION RATE (BUTYL ACETATE = 1): NOT AVAILABLE
SOLUBILITY IN WATER: 100%
APPEARANCE AND ODOR: CLEAR, ODORLESS LIQUID
=====================================================================
NA = Not Applicable NE = Not Established
NL = Not Listed NIF = No Information Found
MSDS: STOP SOLUTION Page 3 of 9
**********************************************************************
4. HEALTH HAZARD DATA:
PRIMARY ROUTE(S) OF ENTRY:
INHALATION? YES SKIN? YES INGESTION? YES
OSHA REGULATED? YES
CARCINOGENICITY: NTP? NA IARC? NA
ACUTE EFFECTS OF OVEREXPOSURE:
EYE: EYE CONTACT WITH THIS PRODUCT CAN CAUSE
IRRITATION AND SEVERE BURNS TO THE EYES AND
MAY DAMAGE THE EYE TISSUES.
SKIN CONTACT: SKIN CONTACT WITH THIS PRODUCT CAN CAUSE
IRRITATION AND MAY CAUSE BURNS. DERMATITIS
HAS BEEN REPORTED FROM FREQUENT SKIN CONTACT
WITH DILUTE SOLUTIONS OF SULFURIC ACID.
SKIN ABSORPTION: NO COMPONENTS ARE KNOWN TO BE AVAILABLE FOR
ABSORPTION THROUGH THE SKIN.
INGESTION: CAN CAUSE SEVERE IRRITATION AND POSSIBLE BURNS
OF THROAT, STOMACH AND GASTROINTESTINAL TRACT.
INHALATION: INHALATION OF MISTS OR VAPORS OF THIS MATERIAL
CAUSES SEVERE IRRITATION AND POSSIBLY
IRREVERSIBLE TISSUE DAMAGE TO THE MEMBRANES OF
THE RESPIRATORY TRACT.
CHRONIC EFFECTS OF EXPOSURE: LONG TERM EXPOSURE TO SULFURIC ACID
SOLUTIONS CAN CAUSE EROSION OF TEETH, IRRITATION OF THE RESPIRATORY
TRACT AND GASTROINTESTINAL DISTURBANCES.
TOXICITY DATA:
EYES: SULFURIC ACID, AT A CONCENTRATION OF APPROXIMATELY
10% HAS BEEN REPORTED TO PRODUCE ONLY MODERATE,
TRANSIENT IRRITATION TO THE EYES OF HUMAN
VOLUNTEERS.
SKIN: SULFURIC ACID, AT A CONCENTRATION OF APPROXIMATELY
10%, HAS BEEN REPORTED TO PRODUCE NEGLIGIBLE
IRRITATION TO THE SKIN OF HUMAN VOLUNTEERS.
DERMATITIS HAS BEEN REPORTED FROM FREQUENT CONTACT
WITH DILUTE SOLUTIONS.
INHALATION: INHALATION OF SULFURIC ACID SOLUTION MISTS OR
VAPORS MAY CAUSE IRREVERSIBLE DAMAGE TO THE TISSUES
OF THE RESPIRATORY TRACT.
**********************************************************************
4. HEALTH HAZARD DATA (CONT):
MSDS: STOP SOLUTION Page 4 of 9
INGESTION: INGESTION OF SULFURIC ACID SOLUTIONS MAY CAUSE
GASTROINTESTINAL DISTURBANCES. LARGER DOSES, OR
MORE CONCENTRATED SOLUTIONS, CAN CAUSE IRREVERSIBLE
TISSUE DAMAGE, ULCERATIONS, AND MAY CAUSE DEATH.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: PERSONS WITH PRE-EXISTING
SKIN DISORDERS OR EYE PROBLEMS OR IMPAIRED RESPIRATORY FUNCTION MAY BE
MORE SUSCEPTIBLE TO THE EFFECTS OF THE SUBSTANCE.
EMERGENCY AND FIRST AID PROCEDURES:
EYE CONTACT: FLUSH EYES IMMEDIATELY WITH PLENTY OF WATER FOR
AT LEAST 15 MINUTES. SEEK MEDICAL ATTENTION.
REMOVE CONTAMINATED CLOTHING.
SKIN CONTACT: REMOVE CONTAMINATED CLOTHING IMMEDIATELY. FLUSH
AFFECTED AREA WITH LARGE AMOUNTS OF WATER. SEEK
MEDICAL ADVICE IF IRRITATION OR REDNESS PERSISTS.
INHALATION: MOVE PERSON TO NON-CONTAMINATED AIR. CALL A
PHYSICIAN IF SYMPTOMS PERSIST.
INGESTION: DRINK LARGE QUANTITIES OF WATER TO DILUTE
CONTENTS OF STOMACH. DO NOT INDUCE VOMITING.
SEEK MEDICAL ATTENTION IMMEDIATELY.
EMERGENCY OVERVIEW: CORROSIVE LIQUID: AVOID CONTACT WITH EYES, SKIN
AND CLOTHING. MAY CAUSE BURNS TO EYES AND SKIN.
=====================================================================
5. FIRE AND EXPLOSION HAZARD:
FLASHPOINT (METHOD USE): NOT APPLICABLE
FLAMMABLE LIMITS: LEL NA UEL NA
EXTINGUISHING MEDIA: USE DRY CHEMICAL, FOAM, OR CARBON DIOXIDE.
SPECIAL FIRE FIGHTING PROCEDURES: WEAR FULL PROTECTIVE CLOTHING;
INCLUDING HELMET, SELF-CONTAINED POSITIVE PRESSURE OR PRESSURE DEMAND
BREATHING APPARATUS, PROTECTIVE CLOTHING AND FACE MASK.
EMERGENCY OVERVIEW: FIREFIGHTERS SHOULD WEAR POSITIVE PRESSURE SELF-
CONTAINED BREATHING APPARATUS AND FULL PROTECTIVE GEAR WHEN FIGHTING
FIRES.
UNUSUAL FIRE AND EXPLOSION HAZARDS: TOXIC FUMES OF OXIDES OF SULFUR.
WILL REACT WITH CARBONATES TO GENERATE CARBON DIOXIDE GAS, AND WITH
CYANIDES AND SULFIDES TO GENERATE POISONOUS HYDROGEN CYANIDE AND
HYDROGEN SULFIDE, RESPECTIVELY.
=====================================================================
**********************************************************************
6. REACTIVITY DATA:
STABILITY: UNSTABLE: CONDITIONS TO AVOID: NONE KNOWN
STABLE: X
MSDS: STOP SOLUTION Page 5 of 9
INCOMPATIBILITY (MATERIALS TO AVOID): BASES ORGANIC MATERIAL,
HALOGENS, METAL ACETYLIDES, OXIDES AND HYDRIDES, STRONG OXIDIZING
AGENTS, AND MANY OTHER REACTIVE SUBSTANCES.
EMERGENCY OVERVIEW: THIS MATERIAL REACTS WITH MOST METALS TO GIVE OFF
FLAMMABLE AND EXPLOSIVE HYDROGEN GAS.
HAZARDOUS DECOMPOSITION OR BY-PRODUCTS: TOXIC FUMES OF OXIDES OF
SULFUR. WILL REACT WITH CARBONATES TO GENERATE CARBON DIOXIDE GAS,
AND WITH CYANIDES AND SULFIDES TO GENERATE POISONOUS HYDROGEN CYANIDE
AND HYDROGEN SULFIDE, RESPECTIVELY.
HAZARDOUS POLYMERIZATION:
MAY OCCUR:
WILL NOT OCCUR: X
=====================================================================
7. SPILL OR LEAK PROCEDURES:
STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED:
GENERAL: DIKE AREA TO PREVENT FURTHER LEAKAGE. WEAR PROTECTIVE
EQUIPMENT AS SPECIFIED IN SECTION 8. AVOID SKIN AND EYE CONTACT.
AVOID BREATHING FUMES OR VAPORS.
LARGE/SMALL SPILL: COVER SPILL AREA WITH SODIUM BICARBONATE AND
ABSORB WITH AN INERT MATERIAL SUCH AS DIRT OR VERMICULITE. PLACE IN A
PROPERLY LABELED CLOSED CONTAINER.
WASTE DISPOSAL METHODS: DISPOSE OF WASTE IN RCRA APPROVED WASTE
DISPOSAL FACILITY IN ACCORDANCE WITH LOCAL, STATE, AND FEDERAL
REGULATIONS.
=====================================================================
8. SPECIAL PROTECTION INFORMATION:
RESPIRATORY PROTECTION (SPECIFY TYPE): NOT NORMALLY NEEDED. IF
PERMISSIBLE LEVELS ARE EXCEEDED USE NIOSH APPROVED FULL FACEPIECE
CHEMICAL CARTRIDGE RESPIRATOR.
VENTILATION: LOCAL EXHAUST: X MECHANICAL:
OTHER:
PROTECTIVE GLOVES: WEAR APPROPRIATE WORK GLOVES, IF NECESSARY FOR
TYPE OF OPERATION.
**********************************************************************
8. SPECIAL PROTECTION INFORMATION (CONT):
EYE PROTECTION: WEAR CHEMICAL GOGGLES OR FULL FACE SHIELD. CONTACT
LENSES SHOULD BE WORN WHEN WORKING WITH THIS MATERIAL. HAVE EYEWASH
FOUNTAIN READILY AVAILABLE IN WORK AREA.
OTHER PROTECTIVE EQUIPMENT: LAB COAT OR APRON. HAVE SAFETY SHOWER
NEARBY.
MSDS: STOP SOLUTION Page 6 of 9
=====================================================================
9. SPECIAL PRECAUTIONS:
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE: AVOID CONTACT WITH
SKIN AND EYES. AVOID BREATHING FUMES OR VAPORS. WASH THOROUGHLY
AFTER HANDLING. KEEP CONTAINER CLOSED AND DRY. STORE IN A COOL, DRY,
WELL-VENTILATED AREA.
=====================================================================
10. OTHER INFORMATION:
TSCA STATUS: ALL COMPONENTS ARE LISTED ON THE TSCA INVENTORY.
CERCLA/SARA: THIS PRODUCT CONTAINS SULFURIC ACID (CAS #7664-93-93, <
15%) WHICH, AS MISTS OR VAPORS, IS SUBJECT TO THE REPORTING
REQUIREMENTS OF SECTION 313 OF SARA AND ITS ASSOCIATED REGULATIONS.
RCRA: WASTE MUST BE HANDLED IN ACCORDANCE WITH ALL APPLICABLE
REGULATIONS.
**********************************************************************
The information herein is given in good faith but no warranty,
expressed or implied, is made.
Page 7 of 9
**********************************************************************
MATERIAL SAFETY DATA SHEET
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
**********************************************************************
DATE PREPARED: 10/5/1999
REVISION: 2
**********************************************************************
1. IDENTIFICATION:
NAME: SUBSTRATE
CAS #: MIXTURE
=====================================================================
2. HAZARDOUS INGREDIENTS:
CHEMICAL NAME/COMMON NAME % EXPOSURE LIMITS
OSHA TWA NIOSH TWA
CAS #
鈮?5
106-69-4 NIF NIF
1,2,6 HEXANETRIOL
鈮?1
67-68-5 NIF NIF
DIMETHYL SULFOXIDE
54827-17-7 NIF NIF NIF
TETRAMETHYLBENZIDINE TMB
7722-84-1 NIF NIF NIF
HYDROGEN PEROXIDE
=====================================================================
3. PHYSICAL DATA:
BOILING POINT: NOT AVAILABLE SPECIFIC GRAVITY (H2O = 1):
APPROXIMATELY 1.0 g/cm3
VAPOR PRESSURE (MM HG.): SOFTENING POINT: N/A
NOT AVAILABLE
pH: 4.78
VAPOR DENSITY (AIR = 1): EVAPORATION RATE (BUTYL ACETATE = 1):
NOT AVAILABLE NOT AVAILABLE
SOLUBILITY IN WATER: 100 % APPEARANCE AND ODOR: CLEAR
ODORLESS LIQUID
=====================================================================
NA = Not Applicable NE = Not Established
NL = Not Listed NIF = No Information Found
MSDS: SUBSTRATE Page 8 of 9
**********************************************************************
4. HEALTH HAZARD DATA:
PRIMARY ROUTE(S) OF ENTRY:
INHALATION? YES SKIN? YES INGESTION? YES
CARCINOGENICITY: NTP? NA IARC? NA
TOXICITY DATA:
TOXIC IF SWALLOWED, INHALED OR ABSORBED THROUGH THE SKIN. CAUSES
EYE, SKIN, MUCOUS MEMBRANE, RESPIRATORY TRACT IRRITATION.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: NONE KNOWN
EMERGENCY AND FIRST AID PROCEDURES:
EYE CONTACT: FLUSH EYES IMMEDIATELY WITH PLENTY OF WATER FOR
AT LEAST 15 MINUTES. CONSULT A PHYSICIAN IF
IRRITATION PERSISTS.
SKIN CONTACT: WASH AFFECTED AREA WITH SOAP AND WATER. SEEK
MEDICAL ADVICE IF IRRITATION OR REDNESS PERSISTS.
INHALATION: MOVE PERSON TO NON-CONTAMINATED AIR. CALL A
PHYSICIAN IF SYMPTOMS PERSIST.
INGESTION: IF SWALLOWED, WASH MOUTH WITH WATER AND CALL A
PHYSICIAN.
EMERGENCY OVERVIEW: PRODUCT PRESENTS MINIMAL HAZARD.
=====================================================================
5. FIRE AND EXPLOSION HAZARD:
FLASHPOINT (METHOD USE): N/A
FLAMMABLE LIMITS: LEL N/A UEL N/A
EXTINGUISHING MEDIA: AS FOR THE SURROUNDING FIRE.
UNUSUAL FIRE AND EXPLOSION HAZARDS: NONE
EMERGENCY OVERVIEW: USE EXTINGUISHING MEDIA SUITABLE FOR SURROUNDING
FIRE. FIREFIGHTERS SHOULD WEAR POSITIVE PRESSURE SELF CONTAINED
BREATHING APPARATUS.
=====================================================================
6. REACTIVITY DATA:
STABILITY: UNSTABLE: CONDITIONS TO AVOID: HEAT,
STABLE: X SUNLIGHT
INCOMPATIBILITY (MATERIALS TO AVOID): OXIDIZIBLE MATERIALS
**********************************************************************
6. REACTIVITY DATA (CONT):
MSDS: SUBSTRATE Page 9 of 9
HAZARDOUS DECOMPOSITION OR BY-PRODUCTS: OXIDES OF CARBON
HAZARDOUS POLYMERIZATION:
MAY OCCUR:
WILL NOT OCCUR: X
=====================================================================
7. SPILL OR LEAK PROCEDURES:
FOR GENERAL SPILLS: DIKE AREA TO PREVENT FURTHER LEAKAGE. FOR
LARGE/SMALL SPILL: COLLECT SPILLED MATERIAL WITH AN INERT
ABSORBENT. PLACE IN A CLOSED CONTAINER.
WASTE DISPOSAL METHODS: DISPOSE OF IN ACCORDANCE WITH LOCAL, STATE,
AND FEDERAL REGULATIONS.
=====================================================================
8. SPECIAL PROTECTION INFORMATION:
RESPIRATORY PROTECTION (SPECIFY TYPE): NOT NORMALLY NEEDED. IF
PERMISSIBLE LEVELS ARE EXCEEDED USE NIOSH APPROVED RESPIRATOR.
VENTILATION: LOCAL EXHAUST: X MECHANICAL:
OTHER:
PROTECTIVE GLOVES: WEAR RUBBER GLOVES
EYE PROTECTION: WEAR CHEMICAL GOGGLES OR FULL FACE SHIELD
OTHER PROTECTIVE EQUIPMENT: LAB COAT OR APRON
=====================================================================
9. SPECIAL PRECAUTIONS:
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE: AVOID CONTACT WITH
SKIN AND EYES. WASH THOROUGHLY AFTER HANDLING. KEEP CONTAINER CLOSED
AND DRY. STORE IN A COOL, DRY AND DARK AREA.
=====================================================================
10. OTHER INFORMATION:
TSCA STATUS: ALL COMPONENTS ARE LISTED ON THE TSCA INVENTORY.
CERCLA/SARA: THIS PRODUCT DOES NOT CONTAIN ANY INGREDIENT WHICH IS
SUBJECT TO THE REPORTING REQUIREMENTS OF SECTION 313 OF SARA AND ITS
ASSOCIATED REGULATIONS.
RCRA: WASTE MUST BE HANDLED IN ACCORDANCE WITH ALL APPLICABLE
REGULATIONS.
**********************************************************************
The information herein is given in good faith but no warranty,
expressed or implied, is made.
|