Page 1 of 13
*********************************************************************
MATERIAL SAFETY DATA SHEET
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
*********************************************************************
DATE PREPARED: 3/12/2008
REVISION: 2
*********************************************************************
1. IDENTIFICATION:
PRODUCT NAME: SUPRE-HEME BUFFER
PRODUCT NO.: 5802
2. INGREDIENTS (THE ABOVE KIT CONTAINS THE FOLLOWING ITEMS):
PRODUCT NUMBER PRODUCT IDENTIFICATION (LABEL NAME) COMMENTS
5802 SUPRE-HEME BUFFER
HAZARDOUS INGREDIENT CAS # %
EDTA ACID 60-00-4 4 MSDS ATTACHED
BORIC ACID 10043-35-3 21 MSDS ATTACHED
TRIS AMINO 77-86-1 75 MSDS ATTACHED
ATTACHED IS/ARE THE MSDS(S) FOR THE ABOVE NAMED HAZARDOUS
INGREDIENT(S).
Page 2 of 13
*********************************************************************
MATERIAL SAFETY DATA SHEET
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
*********************************************************************
DATE PREPARED: 3/12/2008
REVISION: 2
*********************************************************************
1. IDENTIFICATION:
NAME: EDTA ACID
CAS #: 60-00-4
2. HAZARDOUS INGREDIENTS:
CHEMICAL NAME/COMMON NAME % EXPOSURE LIMITS
CAS # OSHA PEL ACGIH TLV
EDTA ACID 100 NL NL
3. PHYSICAL DATA:
BOILING POINT: SPECIFIC GRAVITY (H20 = 1): 0.86 @ 20掳C
VAPOR PRESSURE (MM HG.): MELTING POINT: 220掳C
NEGLIGIBLE
VAPOR DENSITY (AIR = 1): NA
SOLUBILITY IN WATER: APPEARANCE AND ODOR: COLORLESS TO
SLIGHTLY SOLUBLE WHITE CRYSTALS
NA = Not Applicable NE = Not Established
NL = Not Listed NIF = No Information Found
MSDS: EDTA ACID Page 3 of 13
*********************************************************************
4. HEALTH HAZARD DATA:
PRIMARY ROUTE(S) OF ENTRY:
INHALATION? X SKIN? X INGESTION? X
CARCINOGENICITY: NTP? NL IARC? NL
ACUTE EFFECT OF OVEREXPOSURE:
EYES: CAUSES EYE IRRITATION. CAUSES REDNESS AND PAIN.
SKIN: CAUSES SKIN IRRITATION. CAUSES REDNESS AND PAIN.
INGESTION: MAY CAUSE GASTROINTESTINAL IRRITATION WITH
NAUSEA, VOMITING AND DIARRHEA. INGESTION OF
LARGE AMOUNTS CAN CAUSE HYPOCALCEMIC TETANY DUE
TO FORMATION OF CALCIUM COMPLEXES. EXPOSURE MAY
CAUSE KIDNEY INJURY, MUSCLE CRAMPS, BONE-MARROW
DEPRESSION, AND A GENERALIZED ALLERGIC REACTION.
INGESTION OF LARGE QUANTITIES MAY CAUSE
APPRECIABLE SYSTEMIC TOXICITY INVOLVING BLOOD
CHEMISTRY CHANGES DUE TO CHELATION PROPERTIES.
INHALATION: CAUSES IRRITATION OF THE MUCOUS MEMBRANE AND
UPPER RESPIRATORY TRACT.
CHRONIC EFFECTS OF EXPOSURE: MAY CAUSE REPRODUCTIVE AND FETAL
EFFECTS. LABORATORY EXPERIMENTS HAVE RESULTED IN MUTAGENIC EFFECTS.
CHRONIC EXPOSURE MAY CAUSE KIDNEY DAMAGE.
TOXICITY DATA:
LD50/LC50
ORL-MUS LD50=30 MG/KG
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: BEHAVIORAL (CONVULSIONS
OR EFFECT ON SEIZURE THRESHOLD)
EMERGENCY AND FIRST AID PROCEDURES:
EYE CONTACT: IMMEDIATELY FLUSH EYES WITH PLENTY OF WATER FOR
AT LEAST 15 MINUTES, OCCASIONALLY LIFTING THE
UPPER AND LOWER EYELIDS. GET MEDICAL AID.
SKIN CONTACT: GET MEDICAL AID. IMMEDIATELY FLUSH SKIN WITH
PLENTY OF SOAP AND WATER FOR AT LEAST 15 MINUTES
WHILE REMOVING CONTAMINATED CLOTHING AND SHOES.
WASH CLOTHING BEFORE REUSE.
MSDS: EDTA ACID Page 4 of 13
*********************************************************************
4. HEALTH HAZARD DATA (CONT)
INHALATION: REMOVE FROM EXPOSURE TO FRESH AIR IMMEDIATELY.
IF NOT BREATHING, GIVE ARTIFICIAL RESPIRATION.
IF BREATHING IS DIFFICULT, GIVE OXYGEN. GET
MEDICAL AID.
INGESTION: NEVER GIVE ANYTHING BY MOUTH TO AN UNCONSCIOUS
PERSON. GET MEDICAL AID. DO NOT INDUCE
VOMITING. IF CONSCIOUS AND ALERT, RINSE MOUTH
AND DRINK 2-4 CUPFULS OF MILK OR WATER.
5. FIRE AND EXPLOSION HAZARD DATA:
FLASH POINT (METHOD USED): NA
FLAMMABLE LIMITS: LEL NIF UEL NIF
EXTINGUISHING MEDIA: USE WATER SPRAY, DRY CHEMICAL, CARBON DIOXIDE,
OR APPROPRIATE FOAM.
SPECIAL FIRE FIGHTING PROCEDURES: WEAR SELF-CONTAINED BREATHING
APPARATUS AND PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN AND
EYES.
UNUSUAL FIRE AND EXPLOSION HAZARDS: EMITS TOXIC FUMES UNDER FIRE
CONDITIONS.
6. REACTIVITY DATA:
STABILITY: UNSTABLE: STABLE: X
INCOMPATIBILITY (MATERIALS TO AVOID): STRONG OXIDIZING AGENTS,
STRONG BASES, ALUMINUM, COPPER, COPPER ALLOYS, NICKEL.
HAZARDOUS DECOMPOSITION OF BY-PRODUCTS: NITROGEN OXIDES, CARBON
MONOXIDE, IRRITATING AND TOXIC FUMES AND GASES, CARBON DIOXIDE.
HAZARDOUS POLYMERIZATION:
MAY OCCUR: WILL NOT OCCUR: X
7. SPILL OR LEAK PROCEDURES:
STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED: VACUUM OR
SWEEP UP MATERIAL AND PLACE INTO A SUITABLE DISPOSAL CONTAINER.
AVOID RUNOFF INTO STORM SEWERS AND DITCHES WHICH LEAD TO WATERWAYS.
CLEAN UP SPILLS IMMEDIATELY, OBSERVING PRECAUTIONS IN THE PROTECTIVE
EQUIPMENT SECTION. AVOID GENERATING DUSTY CONDITIONS. PROVIDE
VENTILATION.
MSDS: EDTA ACID Page 5 of 13
*********************************************************************
7. SPILL OR LEAK PROCEDURES (CONT):
WASTE DISPOSAL METHODS: DISSOLVE OR MIX THE MATERIAL WITH A
COMBUSTIBLE SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH
AN AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGULATIONS.
8. SPECIAL PROTECTION INFORMATION:
RESPIRATORY PROTECTION (SPECIFY TYPE): NIOSH/MSHA-APPROVED
RESPIRATOR.
VENTILATION: LOCAL EXHAUST: MECHANICAL: X
OTHER:
PROTECTIVE GLOVES: COMPATIBLE CHEMICAL-RESISTANT GLOVES.
EYE PROTECTION: CHEMICAL SAFETY GOGGLES.
OTHER PROTECTIVE EQUIPMENT: NONE
9. SPECIAL PRECAUTIONS:
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE: STORE IN COOL DRY
PLACE.
OTHER PRECAUTIONS:
10. OTHER INFORMATION:
NONE
*********************************************************************
The information herein is given in good faith but no warranty,
expressed or implied, is made.
Page 6 of 13
*********************************************************************
MATERIAL SAFETY DATA SHEET
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
*********************************************************************
DATE PREPARED: 3/12/2008
REVISION: 2
*********************************************************************
1. IDENTIFICATION:
NAME: BORIC ACID (ORTIBOR)
CAS #: 10043-35-3
2. HAZARDOUS INGREDIENTS:
CHEMICAL NAME/COMMON NAME % EXPOSURE LIMITS
CAS # OSHA PEL ACGIH TLV
ORTIBOR BORIC ACID > 99 15 MG/M3 10 MG/M3
3. PHYSICAL DATA:
BOILING POINT: SPECIFIC GRAVITY (H20 = 1): 1.51
VAPOR PRESSURE (MM HG.): MELTING POINT: 170.9掳C (340掳F)
NEGLIGIBLE
VAPOR DENSITY (AIR = 1): NIF pH: 5.1 (1.0% SOLUTION)
SOLUBILITY IN WATER: APPEARANCE AND ODOR: WWHITE
4.7% @ 20掳C ODORLESS SOLID
27.5% @ 100掳C
NA = Not Applicable NE = Not Established
NL = Not Listed NIF = No Information Found
BORIC ACID (ORTIBOR) Page 7 of 13
*********************************************************************
4. HEALTH HAZARD DATA:
PRIMARY ROUTE(S) OF ENTRY:
INHALATION? X SKIN? INGESTION?
CARCINOGENICITY: NTP? IARC?
ACUTE EFFECT OF OVEREXPOSURE:
EYES: NON-IRRITANT
SKIN: NON-IRRITANT
INHALATION: OCCASIONAL MILD IRRITATION EFFECTS TO NOSE AND
THROAT MAY OCCUR FROM INHALATION OF OPTIBOR DUST
AT LEVELS GREATER THAN 10 MG/M3.
INGESTION: OPTIBOR HAS A LOW ACUTE TOXICITY. SMALL AMOUNTS
(E.G., A TEASPOONFUL) SWALLOWED ACCIDENTALLY ARE
NOT LIKELY TO CAUSE EFFECTS; SWALLOWING AMOUNTS
LARGER THAN THAT MAY CAUSE GASTROINTESTINAL
SYMPTOMS.
CHRONIC EFFECTS OF EXPOSURE: HUMAN EPIDEMIOLOGICAL STUDIES SHOW NO
INCREASE IN PULMONARY DISEASE IN OCCUPATIONAL POPULATIONS WITH
CHRONIC EXPOSURES TO BORIC ACID DUST AND SODIUM BORATE DUST. A
RECENT EPIDEMIOLOGY STUDY UNDER THE CONDITIONS OF NORMAL OCCUPATIONAL
EXPOSURE TO BORATE DUSTS INDICATED NO EFFECT ON FERTILITY.
TOXICITY DATA:
INGESTION: LOW ACUTE ORAL TOXICITY; LD50 IN RATS IS 3,500 TO 4,100
MG/KG OF BODY WEIGHT.
SKIN/DERMAL: LOW ACUTE DERMAL TOXICITY; LD50 IN RABBITS IS GREATER
THAN 2,000 MG/KG OF BODY WEIGHT. OPTIBOR IS POORLY ABSORBED THROUGH
INTACT SKIN.
INHALATION: LOW ACUTE INHALATION TOXICITY; LC50 IN RATS IS GREATER
THAN 2.0 MG/L (OR G/M3).
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE:
EMERGENCY AND FIRST AID PROCEDURES:
EYE CONTACT: USE EYE WASH FOUNTAIN OR FRESH WATER TO
CLEANSE EYE. IF IRRITATION PERSISTS FOR MORE
THAN 30 MINUTES, SEEK MEDICAL ATTENTION.
SKIN CONTACT: NO TREATMENT NECESSARY BECAUSE NON-IRRITATING.
INHALATION: IF SYMPTOMS SUCH AS NOSE OR THROAT IRRITATION
ARE OBSERVED, REMOVE PERSON TO FRESH AIR.
BORIC ACID (ORTIBOR) Page 8 of 13
*********************************************************************
4. HEALTH HAZARD DATA (CONT):
INGESTION: SWALLOWING SMALL QUANTITIES (ONE TEASPOON) WILL
CAUSE NO HARM TO HEALTHY ADULTS. IF LARGER
AMOUNTS ARE SWALLOWED, GIVE TWO GLASSES OF
WATER TO DRINK AND SEEK MEDICAL ATTENTION.
5. FIRE AND EXPLOSION HAZARD DATA:
FLASH POINT (METHOD USED): NL
FLAMMABLE LIMITS: NONE LEL UEL
EXTINGUISHING MEDIA: ANY FIRE EXTINGUISHING MEDIA
SPECIAL FIRE FIGHTING PROCEDURES: NONE
UNUSUAL FIRE AND EXPLOSION HAZARDS: NONE
6. REACTIVITY DATA:
STABILITY: UNSTABLE: STABLE: X
INCOMPATIBILITY (MATERIALS TO AVOID): OPTIBOR REACTS AS A WEAK ACID
WHICH MAY CAUSE CORROSION OF BASE METALS. REACTION WITH STRONG
REDUCING AGENTS, SUCH AS METAL HYDRIDES OR ALKALI METALS, WILL
GENERATE HYDROGEN GAS, WHICH COULD CREATE AN EXPLOSIVE HAZARD.
HAZARDOUS DECOMPOSITION OF BY-PRODUCTS: NONE
HAZARDOUS POLYMERIZATION:
MAY OCCUR: WILL NOT OCCUR: X
7. SPILL OR LEAK PROCEDURES:
STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED:
GENERAL: OPTIBOR IS A WATER-SOLUBLE WHITE POWDER THAT MAY, AT HIGH
CONCENTRATIONS, CAUSE DAMAGE TO TREES OR VEGETATION BY ROOT
ABSORPTION. (REFER TO ECOLOGICAL INFORMATION, SECTION 12, FOR
SPECIFIC INFORMATION.)
LAND SPILL: VACUUM, SHOVEL OR SWEEP UP OPTIBOR AND PLACE IN
CONTAINERS FOR DISPOSAL IN ACCORDANCE WITH APPLICABLE LOCAL
REGULATIONS. AVOID CONTAMINATION OF WATER BODIES DURING CLEANUP AND
DISPOSAL. NO PERSONAL PROTECTIVE EQUIPMENT IS NEEDED TO CLEANUP LAND
SPILLS.
SPILLAGE INTO WATER. WHERE POSSIBLE, REMOVE ANY INTACT CONTAINERS
FROM THE WATER. ADVISE LOCAL WATER AUTHORITY THAT NONE OF THE
AFFECTED WATER SHOULD BE USED FOR IRRIGATION OR FOR THE ABSTRACTION
OF POTABLE WATER UNTIL NATURAL DILUTION RETURNS THE BORON VALUE TO
ITS NORMAL ENVIRONMENTAL BACKGROUND LEVEL. OPTIBOR IS A NON-
HAZARDOUS WASTE WHEN SPILLED OR DISPOSED OF, AS DEFINED IN THE
BORIC ACID (ORTIBOR) Page 9 of 13
*********************************************************************
7. SPILL OR LEAK PROCEDURES (CONT):
RESOURCE CONSERVATION AND RECOVERY ACT (RCRA) REGULATIONS (40 CFR
261). (REFER TO REGULATORY INFORMATION, SECTION 15, FOR ADDITIONAL
REFERENCES.)
WASTE DISPOSAL METHODS: SMALL QUANTITIES OF OPTIBOR CAN USUALLY BE
DISPOSED OF AT LANDFILL SITES. NO SPECIAL DISPOSAL TREATMENT IS
REQUIRED, BUT LOCAL AUTHORITIES SHOULD BE CONSULTED ABOUT ANY
SPECIFIC LOCAL REQUIREMENTS.
8. SPECIAL PROTECTION INFORMATION:
RESPIRATORY PROTECTION (SPECIFY TYPE): NIOSH/MSHA APPROVED
RESPIRATOR
VENTILATION: LOCAL EXHAUST: X MECHANICAL:
OTHER:
PROTECTIVE GLOVES: NOT REQUIRED
EYE PROTECTION: NOT REQUIRED
OTHER PROTECTIVE EQUIPMENT:
9. SPECIAL PRECAUTIONS:
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE: DRY INDOOR STORAGE
IS RECOMMENDED.
OTHER PRECAUTIONS: NONE
10. OTHER INFORMATION:
*********************************************************************
The information herein is given in good faith but no warranty,
expressed or implied, is made.
Page 10 of 13
*********************************************************************
MATERIAL SAFETY DATA SHEET
HELENA LABORATORIES
1530 Lindbergh Dr./P.O. Box 752
Beaumont, TX 77704-0752
USA Toll Free 800-231-5663
*********************************************************************
DATE PREPARED: 3/12/2008
REVISION: 1
*********************************************************************
1. IDENTIFICATION:
NAME: TRIS AMINO
CAS #: 77-86-1
2. HAZARDOUS INGREDIENTS:
CHEMICAL NAME/COMMON NAME % EXPOSURE LIMITS
CAS # OSHA PEL ACGIH TLV
TRIS AMINO 100 NA NA
3. PHYSICAL DATA:
BOILING POINT: NA SPECIFIC GRAVITY (H20 = 1): NIF
VAPOR PRESSURE (MM HG.): NIF MELTING POINT: 150-152掳C
VAPOR DENSITY (AIR = 1): NIF
SOLUBILITY IN WATER: APPEARANCE AND ODOR: SOLID
80 g/100 ML water
NA = Not Applicable NE = Not Established
NL = Not Listed NIF = No Information Found
MSDS: TRIS AMINO Page 11 of 13
*********************************************************************
4. HEALTH HAZARD DATA:
PRIMARY ROUTE(S) OF ENTRY:
INHALATION? X SKIN? X INGESTION? X
CARCINOGENICITY: NTP? NIF IARC? NIF
ACUTE EFFECT OF OVEREXPOSURE:
EYES: CAUSES EYE IRRITATION
SKIN: IRRITANT TO SKIN
INHALATION: MAY BE HARMFUL IF INHALED
INGESTION: MAYBE BE HARMFUL IF SWALLOWED
CHRONIC EFFECTS OF EXPOSURE: MATERIAL IS IRRITATING TO MUCOUS
MEMBRANES AND UPPER RESPIRATORY TRACT.
TOXICITY DATA: NIF
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: NIF
EMERGENCY AND FIRST AID PROCEDURES:
EYE CONTACT: IN CASE OF CONTACT WITH EYES, FLUSH WITH
COPIOUS AMOUNTS OF WATER FOR AT LEAST 15
MINUTES. ASSURE ADEQUATE FLUSHING BY
SEPARATING THE EYELIDS WITH FINGERS. CALL A
PHYSICIAN.
SKIN CONTACT: IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH
SOAP AND COPIOUS AMOUNTS OF WATER.
INHALATION: IF INHALED, REMOVE TO FRESH AIR. IF BREATHING
BECOMES DIFFICULT, CALL A PHYSICIAN.
INGESTION: IF SWALLOWED, WASH OUT MOUTH WITH WATER
PROVIDED PERSON IS CONSCIOUS.
5. FIRE AND EXPLOSION HAZARD DATA:
FLASH POINT (METHOD USED): NA
FLAMMABLE LIMITS: LEL NIF UEL NIF
EXTINGUISHING MEDIA: WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL
POWDER OR APPROPRIATE FOAM.
MSDS: TRIS AMINO Page 12 of 13
*********************************************************************
5. FIRE AND EXPLOSION HAZARD DATA (CONT):
SPECIAL FIRE FIGHTING PROCEDURES: WEAR SELF-CONTAINED BREATHING
APPARATUS AND PROTECTIVE CLOTHING
TO PREVENT CONTACT WITH SKIN AND
EYES.
UNUSUAL FIRE AND EXPLOSION HAZARDS: EMITS TOXIC FUMES UNDER FIRE
CONDITIONS
6. REACTIVITY DATA:
STABILITY: UNSTABLE: STABLE: X
INCOMPATIBILITY (MATERIALS TO AVOID): HEAVY METALS, SALTS, RUBBER,
OXYGEN, OXIDIZING AGENTS.
HAZARDOUS DECOMPOSITION OF BY-PRODUCTS: CARBON MONOXIDE, CARBON
DIOXIDE, NITROGEN OXIDES, SULFUR OXIDES
HAZARDOUS POLYMERIZATION:
MAY OCCUR: WILL NOT OCCUR: X
7. SPILL OR LEAK PROCEDURES:
STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED:
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES. SWEEP UP, PLACE IN BAG AND HOLD FOR WASTE DISPOSAL.
AVOID RAISING DUST. VENTILATE AREA AND WASH SPILL SITE AFTER
MATERIAL PICKUP IS COMPLETE.
WASTE DISPOSAL METHODS: DISSOLVE OR MIX THE MATERIAL WITH A
COMBUSTIBLE SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH
AN AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE, AND LOCAL
REGULATIONS.
8. SPECIAL PROTECTION INFORMATION:
RESPIRATORY PROTECTION (SPECIFY TYPE): NIOSH/MSHA APPROVED
VENTILATION: LOCAL EXHAUST: MECHANICAL: X
OTHER:
PROTECTIVE GLOVES: CHEMICAL RESISTANT GLOVES
EYE PROTECTION: CHEMCIAL SAFETY GOGGLES
OTHER PROTECTIVE EQUIPMENT: NIF
MSDS: TRIS AMINO Page 13 of 13
*********************************************************************
9. SPECIAL PRECAUTIONS:
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE: STORE AT -20掳C.
OTHER PRECAUTIONS: NONE
10. OTHER INFORMATION: NONE
*********************************************************************
The information herein is given in good faith but no warranty,
expressed or implied, is made.
|