BUTYL GLYCOL ACETATE
(Chemwatch name: ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 12164
Issue Date: 12-Sep-2006 Version No:1
NC317TLP CD 2007/3 Page 1 of 12
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
BUTYL GLYCOL ACETATE
SYNONYMS
C8-H16-O3, "2-butoxyethanol acetate", "2-butoxyethanol acetate", "2-butoxyethyl acetate",
"2-butoxyethyl acetate", "butyl glycol acetate (european)", "butylglycol acetate
(european)", "glycol monobutyl ether acetate", "glycol ether EB acetate", "ethanol 2
-butoxy acetate", "ethanol 2-butoxy acetate"
PRODUCT USE
Solvent for nitrocellulose, cellulose acetate, various gums, resins, waxes, oils; textile
printing, photographic film, lacquers, dopes. Also used in latex paints as coalescent and
in hard surface cleaners.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Quantum Industrial Park
Dandenong South VIC 3175
Australia
Telephone: 1300 782 688
Emergency Tel: 1300 131 001
Fax: 1300 782 699
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
BUTYL GLYCOL ACETATE
(Chemwatch name: ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 12164
Issue Date: 12-Sep-2006 Version No:1
NC317TLP CD 2007/3 Page 2 of 12
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to the Criteria of
NOHSC, and the ADG Code.
POISONS SCHEDULE
S6
RISK SAFETY
May form explosive peroxides. Do not breathe gas/ fumes/ vapour/ spray.
Harmful by inhalation and in contact with skin. Use only in well ventilated areas.
Ingestion may produce health damage*. Keep container in a well ventilated place.
Cumulative effects may result following Avoid exposure - obtain special instructions
exposure*. before use.
May produce discomfort of the eyes and skin*. To clean the floor and all objects contaminated
by this material use water.
May possibly affect fertility*. Keep container tightly closed.
* (limited evidence). Keep away from food drink and animal feeding
stuffs.
Take off immediately all contaminated clothing.
In case of contact with eyes rinse with plenty
of water and contact Doctor or Poisons
Information Centre.
If swallowed IMMEDIATELY contact Doctor or
Poisons Information Centre (show this container
or label).
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
ethylene glycol monobutyl ether acetate 112-07-2 > 99
Section 4 - FIRST AID MEASURES
SWALLOWED
路 If swallowed do NOT induce vomiting.
路 If vomiting occurs, lean patient forward or place on left side (head-down position, if
possible) to maintain open airway and prevent aspiration.
路 Observe the patient carefully.
路 Never give liquid to a person showing signs of being sleepy or with reduced awareness;
i.e. becoming unconscious.
路 Give water to rinse out mouth, then provide liquid slowly and as much as casualty can
comfortably drink.
路 Seek medical advice.
BUTYL GLYCOL ACETATE
(Chemwatch name: ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 12164
Issue Date: 12-Sep-2006 Version No:1
NC317TLP CD 2007/3 Page 3 of 12
Section 4 - FIRST AID MEASURES
EYE
If this product comes in contact with the eyes:
路 Wash out immediately with fresh running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 If pain persists or recurs seek medical attention.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
SKIN
If skin contact occurs:
路 Immediately remove all contaminated clothing, including footwear.
路 Flush skin and hair with running water (and soap if available).
路 Seek medical attention in event of irritation.
INHALED
路 If fumes or combustion products are inhaled remove from contaminated area.
路 Lay patient down. Keep warm and rested.
路 Prostheses such as false teeth, which may block airway, should be removed, where
possible, prior to initiating first aid procedures.
路 Apply artificial respiration if not breathing, preferably with a demand valve
resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary.
路 Transport to hospital, or doctor.
NOTES TO PHYSICIAN
Followed acute or short term repeated exposures to ethylene glycol monoalkyl ethers and
their acetates:
路 Hepatic metabolism produces ethylene glycol as a metabolite.
路 Clinical presentation, following severe intoxication, resembles that of ethylene glycol
exposures.
路 Monitoring the urinary excretion of the alkoxyacetic acid metabolites may be a useful
indication of exposure.
[Ellenhorn and Barceloux: Medical Toxicology].
For acute or short term repeated exposures to ethylene glycol:
路 Early treatment of ingestion is important. Ensure emesis is satisfactory.
路 Test and correct for metabolic acidosis and hypocalcaemia.
路 Apply sustained diuresis when possible with hypertonic mannitol.
路 Evaluate renal status and begin haemodialysis if indicated. [I.L.O]
路 Rapid absorption is an indication that emesis or lavage is effective only in the first
few hours. Cathartics and charcoal are generally not effective.
路 Correct acidosis, fluid/electrolyte balance and respiratory depression in the usual
manner. Systemic acidosis (below 7.2) can be treated with intravenous sodium bicarbonate
solution.
路 Ethanol therapy prolongs the half-life of ethylene glycol and reduces the formation of
toxic metabolites.
路 Pyridoxine and thiamine are cofactors for ethylene glycol metabolism and should be
given (50 to 100 mg respectively) intramuscularly, four times per day for 2 days.
路 Magnesium is also a cofactor and should be replenished. The status of 4-methylpyrazole,
in the treatment regime, is still uncertain. For clearance of the material and its
metabolites, haemodialysis is much superior to peritoneal dialysis.
[Ellenhorn and Barceloux: Medical Toxicology]
It has been suggested that there is a need for establishing a new biological exposure
limit before a workshift that is clearly below 100 mmol ethoxy-acetic acids per mole
creatinine in morning urine of people occupationally exposed to ethylene glycol ethers.
This arises from the finding that an increase in urinary stones may be associated with
such exposures.
Laitinen J., et al: Occupational & Environmental Medicine 1996; 53, 595-600.
BUTYL GLYCOL ACETATE
(Chemwatch name: ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 12164
Issue Date: 12-Sep-2006 Version No:1
NC317TLP CD 2007/3 Page 4 of 12
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 Water spray or fog.
路 Foam.
路 Dry chemical powder.
路 BCF (where regulations permit).
路 Carbon dioxide.
FIRE FIGHTING
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Wear full body protective clothing with breathing apparatus.
路 Prevent, by any means available, spillage from entering drains or water course.
路 Use water delivered as a fine spray to control fire and cool adjacent area.
路 Avoid spraying water onto liquid pools.
路 DO NOT approach containers suspected to be hot.
路 Cool fire exposed containers with water spray from a protected location.
路 If safe to do so, remove containers from path of fire.
FIRE/EXPLOSION HAZARD
路 Combustible.
路 Slight fire hazard when exposed to heat or flame.
路 Heating may cause expansion or decomposition leading to violent rupture of containers.
路 On combustion, may emit toxic fumes of carbon monoxide (CO).
路 May emit acrid smoke.
路 Mists containing combustible materials may be explosive.
Combustion products include: carbon dioxide (CO2), other pyrolysis products typical of
burning organic material.
May emit poisonous fumes.
May emit corrosive fumes.
FIRE INCOMPATIBILITY
Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine
bleaches, pool chlorine etc. as ignition may result.
HAZCHEM: None
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
路 Remove all ignition sources.
路 Clean up all spills immediately.
路 Avoid breathing vapours and contact with skin and eyes.
路 Control personal contact by using protective equipment.
路 Contain and absorb spill with sand, earth, inert material or vermiculite.
路 Wipe up.
路 Place in a suitable labelled container for waste disposal.
MAJOR SPILLS
Moderate hazard.
路 Clear area of personnel and move upwind.
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Wear breathing apparatus plus protective gloves.
路 Prevent, by any means available, spillage from entering drains or water course.
BUTYL GLYCOL ACETATE
(Chemwatch name: ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 12164
Issue Date: 12-Sep-2006 Version No:1
NC317TLP CD 2007/3 Page 5 of 12
Section 6 - ACCIDENTAL RELEASE MEASURES
路 No smoking, naked lights or ignition sources.
路 Increase ventilation.
路 Stop leak if safe to do so.
路 Contain spill with sand, earth or vermiculite.
路 Collect recoverable product into labelled containers for recycling.
路 Absorb remaining product with sand, earth or vermiculite.
路 Collect solid residues and seal in labelled drums for disposal.
路 Wash area and prevent runoff into drains.
路 If contamination of drains or waterways occurs, advise emergency services.
EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)
The maximum airborne concentration below which it is believed that nearly all individuals could be exposed
for up to one hour WITHOUT experiencing or developing
life-threatening health effects is:
ethylene glycol monobutyl ether acetate 150 ppm
irreversible or other serious effects or symptoms which could impair an individual's ability to take
protective action is:
ethylene glycol monobutyl ether acetate 25 ppm
other than mild, transient adverse effects without perceiving a clearly defined odour is:
ethylene glycol monobutyl ether acetate 15 ppm
The threshold concentration below which most people will experience no appreciable risk of health effects:
ethylene glycol monobutyl ether acetate 5 ppm
American Industrial Hygiene Association (AIHA)
Ingredients considered according to the following cutoffs
Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0%
R50 >= 0.25% Corrosive (C) >= 5.0%
R51 >= 2.5%
else >= 10%
where percentage is percentage of ingredient found in the mixture
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
The substance accumulates peroxides which may become hazardous only if it evaporates or
is distilled or otherwise treated to concentrate the peroxides. The substance may
concentrate around the container opening for example.
Purchases of peroxidisable chemicals should be restricted to ensure that the chemical is
used completely before it can become peroxidised.
路 A responsible person should maintain an inventory of peroxidisable chemicals or
annotate the general chemical inventory to indicate which chemicals are subject to
peroxidation. An expiration date should be determined. The chemical should either be
treated to remove peroxides or disposed of before this date.
路 The person or laboratory receiving the chemical should record a receipt date on the
bottle. The individual opening the container should add an opening date.
路 Unopened containers received from the supplier should be safe to store for 18 months.
路 Opened containers should not be stored for more than 12 months.
路 Avoid all personal contact, including inhalation.
路 Wear protective clothing when risk of exposure occurs.
路 Use in a well-ventilated area.
BUTYL GLYCOL ACETATE
(Chemwatch name: ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 12164
Issue Date: 12-Sep-2006 Version No:1
NC317TLP CD 2007/3 Page 6 of 12
Section 7 - HANDLING AND STORAGE
路 Prevent concentration in hollows and sumps.
路 DO NOT enter confined spaces until atmosphere has been checked.
路 Avoid smoking, naked lights or ignition sources.
路 Avoid contact with incompatible materials.
路 When handling, DO NOT eat, drink or smoke.
路 Keep containers securely sealed when not in use.
路 Avoid physical damage to containers.
路 Always wash hands with soap and water after handling.
路 Work clothes should be laundered separately.
路 Use good occupational work practice.
路 Observe manufacturer's storing and handling recommendations.
路 Atmosphere should be regularly checked against established exposure standards to
ensure safe working conditions.
DO NOT allow clothing wet with material to stay in contact with skin.
SUITABLE CONTAINER
路 Metal can or drum
路 Packaging as recommended by manufacturer.
路 Check all containers are clearly labelled and free from leaks.
STORAGE INCOMPATIBILITY
Glycol ethers may form peroxides under certain conditions. In the presence of strong
bases or the salts of strong bases, at elevated temperatures, the potential exists for
runaway reactions. Contact with aluminium should be avoided. Release of hydrogen gas may
result.
Avoid reaction with oxidising agents.
STORAGE REQUIREMENTS
路 Store in original containers.
路 Keep containers securely sealed.
路 No smoking, naked lights or ignition sources.
路 Store in a cool, dry, well-ventilated area.
路 Store away from incompatible materials and foodstuff containers.
路 Protect containers against physical damage and check regularly for leaks.
路 Observe manufacturer's storing and handling recommendations.
_____________________________________________________
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
+ X + X 0 +
_____________________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA ppm TWA mg/m鲁 STEL ppm STEL mg/m鲁
_________ _________ _____ _____ _____ _____
Australia ethylene glycol 20 133 50 333
Exposure monobutyl ether
Standards acetate (2-
Butoxyethyl
acetate)
BUTYL GLYCOL ACETATE
(Chemwatch name: ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 12164
Issue Date: 12-Sep-2006 Version No:1
NC317TLP CD 2007/3 Page 7 of 12
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
MATERIAL DATA
Sensory irritants are chemicals that produce temporary and undesirable side-effects on
the eyes, nose or throat. Historically occupational exposure standards for these
irritants have been based on observation of workers' responses to various airborne
concentrations. Present day expectations require that nearly every individual should be
protected against even minor sensory irritation and exposure standards are established
using uncertainty factors or safety factors of 5 to 10 or more. On occasion animal no
-observable-effect-levels (NOEL) are used to determine these limits where human results
are unavailable. An additional approach, typically used by the TLV committee (USA) in
determining respiratory standards for this group of chemicals, has been to assign ceiling
values (TLV C) to rapidly acting irritants and to assign short-term exposure limits (TLV
STELs) when the weight of evidence from irritation, bioaccumulation and other endpoints
combine to warrant such a limit. In contrast the MAK Commission (Germany) uses a five
-category system based on intensive odour, local irritation, and elimination half-life.
However this system is being replaced to be consistent with the European Union (EU)
Scientific Committee for Occupational Exposure Limits (SCOEL); this is more closely
allied to that of the USA.
OSHA (USA) concluded that exposure to sensory irritants can:
路 cause inflammation
路 cause increased susceptibility to other irritants and infectious agents
路 lead to permanent injury or dysfunction
路 permit greater absorption of hazardous substances and
路 acclimate the worker to the irritant warning properties of these substances thus
increasing the risk of overexposure.
Threshold odour concentration: 50% recognition, 0.64 ppm.
Toxic doses cause red blood cell lysis, and in consequence,
haemoglobinuria and sometimes, kidney damage.
PERSONAL PROTECTION
EYE
路 Safety glasses with side shields.
路 Chemical goggles.
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
Suitability and durability of glove type is dependent on usage. Factors such as:
路 frequency and duration of contact,
路 chemical resistance of glove material,
路 glove thickness and
路 dexterity,
are important in the selection of gloves.
BUTYL GLYCOL ACETATE
(Chemwatch name: ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 12164
Issue Date: 12-Sep-2006 Version No:1
NC317TLP CD 2007/3 Page 8 of 12
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
Wear chemical protective gloves, eg. PVC.
Wear safety footwear or safety gumboots, eg. Rubber.
OTHER
路 Overalls.
路 P.V.C. apron.
路 Barrier cream.
路 Skin cleansing cream.
路 Eye wash unit.
GLOVE SELECTION INDEX
Glove selection is based on a modified presentation of the:
" Forsberg Clothing Performance Index" .
The effect(s) of the following substance(s) are taken into account in the
computer- generated selection: ethylene glycol monobutyl ether acetate
Protective Material CPI *.
__________________________________________
NAT+NEOPR+NITRILE C
__________________________________________
* CPI - Chemwatch Performance Index
A: Best Selection
B: Satisfactory; may degrade after 4 hours continuous immersion
C: Poor to Dangerous Choice for other than short term immersion
NOTE: As a series of factors will influence the actual performance of the glove,
a final selection must be based on detailed observation. -
* Where the glove is to be used on a short term, casual or infrequent basis,
factors such as "feel" or convenience (e.g. disposability), may dictate a choice
of gloves which might otherwise be unsuitable following long-term or frequent use.
A qualified practitioner should be consulted.
RESPIRATOR
Selection of the Class and Type of respirator will depend upon the level of breathing
zone contaminant and the chemical nature of the contaminant. Protection Factors (defined
as the ratio of contaminant outside and inside the mask) may also be important.
Breathing Zone Level Maximum Protection Half- face Respirator Full- Face Respirator
ppm (volume) Factor
1000 10 A- AUS -
1000 50 - A- AUS
5000 50 Airline * -
5000 100 - A- 2
10000 100 - A- 3
100+ Airline**
* - Continuous Flow ** - Continuous-flow or positive pressure demand.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
Local exhaust ventilation usually required. If risk of overexposure exists, wear approved
respirator. Correct fit is essential to obtain adequate protection. Supplied-air type
respirator may be required in special circumstances. Correct fit is essential to ensure
adequate protection.
An approved self contained breathing apparatus (SCBA) may be required in some situations.
Provide adequate ventilation in warehouse or closed storage area. Air contaminants
BUTYL GLYCOL ACETATE
(Chemwatch name: ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 12164
Issue Date: 12-Sep-2006 Version No:1
NC317TLP CD 2007/3 Page 9 of 12
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
generated in the workplace possess varying "escape" velocities which, in turn, determine
the "capture velocities" of fresh circulating air required to effectively remove the
contaminant.
Type of Contaminant: Air Speed:
solvent, vapours, degreasing etc., evaporating 0.25- 0.5 m/s (50- 100 f/min.)
from tank (in still air).
aerosols, fumes from pouring operations, 0.5- 1 m/s (100- 200 f/min.)
intermittent container filling, low speed
conveyer transfers, welding, spray drift,
plating acid fumes, pickling (released at low
velocity into zone of active generation)
direct spray, spray painting in shallow booths, 1- 2.5 m/s (200- 500 f/min.)
drum filling, conveyer loading, crusher dusts,
gas discharge (active generation into zone of
rapid air motion)
grinding, abrasive blasting, tumbling, high 2.5- 10 m/s (500- 2000 f/min.)
speed wheel generated dusts (released at high
initial velocity into zone of very high rapid
air motion).
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only.
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood- local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
source. The air velocity at the extraction fan, for example, should be a minimum of 1-2
m/s (200-400 f/min) for extraction of solvents generated in a tank 2 meters distant from
the extraction point. Other mechanical considerations, producing performance deficits
within the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or used.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Colourless liquid with pleasant ester- like odour. Mixes with water and common organic
solvents.
PHYSICAL PROPERTIES
Liquid.
Mixes with water.
Molecular Weight: 160.2 Boiling Range (掳C): 192
Melting Range (掳C): - 63 Specific Gravity (water=1): 0.942
BUTYL GLYCOL ACETATE
(Chemwatch name: ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 12164
Issue Date: 12-Sep-2006 Version No:1
NC317TLP CD 2007/3 Page 10 of 12
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Solubility in water (g/L): Miscible pH (as supplied): Not applicable
pH (1% solution): Not available. Vapour Pressure (kPa): Very low
Volatile Component (%vol): 100 Evaporation Rate: 0.3 (BuAc=1)
Relative Vapour Density (air=1): 5.5 Flash Point (掳C): 74
Lower Explosive Limit (%): 0.5 (135C) Upper Explosive Limit (%): 8.5 (135C)
Autoignition Temp (掳C): 340 Decomposition Temp (掳C): Not available.
State: Liquid Viscosity: Not Available
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
路 Presence of incompatible materials.
路 Product is considered stable.
路 Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
Overexposure is unlikely in this form.
Accidental ingestion of the material may be damaging to the health of the individual.
EYE
Limited evidence or practical experience suggests, that the material may cause eye
irritation in a substantial number of individuals. Prolonged eye contact may cause
inflammation characterised by a temporary redness of the conjunctiva (similar to
windburn).
SKIN
Skin contact with the material may be harmful; systemic effects may result following
absorption.
There is some evidence to suggest that the material may cause mild but significant
inflammation of the skin either following direct contact or after a delay of some time.
Repeated exposure can cause contact dermatitis which is characterised by redness,
swelling and blistering.
Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may
produce systemic injury with harmful effects. Examine the skin prior to the use of the
material and ensure that any external damage is suitably protected.
INHALED
Inhalation of vapours or aerosols (mists, fumes), generated by the material during the
course of normal handling, may be harmful.
Inhalation hazard is increased at higher temperatures.
The material is not thought to produce respiratory irritation (as classified by EC
Directives using animal models). Nevertheless inhalation of vapours, fumes or aerosols,
especially for prolonged periods, may produce respiratory discomfort and occasionally,
distress.
CHRONIC HEALTH EFFECTS
Substance accumulation, in the human body, may occur and may cause some concern following
repeated or long-term occupational exposure.
Based on experience with similar materials, there is a possibility that exposure to the
material may reduce fertility in humans at levels which do not cause other toxic effects.
BUTYL GLYCOL ACETATE
(Chemwatch name: ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 12164
Issue Date: 12-Sep-2006 Version No:1
NC317TLP CD 2007/3 Page 11 of 12
Section 11 - TOXICOLOGICAL INFORMATION
Ethylene glycol esters and their ethers cause wasting of the testicles, reproductive
changes, infertility and changes to kidney function. Shorter chain compounds are more
dangerous. They are also associated with the formation of stones in the urine.
TOXICITY AND IRRITATION
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (rat) LD50: 2400 mg/kg Skin (rabbit): 500 mg - Mild
Dermal (rabbit) LD50: 1500 mg/kg Eye (rabbit): 500 mg/24hr - Mild
Oral (Mouse) LD50: 3200 mg/kg
The material may be irritating to the eye, with prolonged contact causing inflammation.
Repeated or prolonged exposure to irritants may produce conjunctivitis.
The material may cause skin irritation after prolonged or repeated exposure and may
produce on contact skin redness, swelling, the production of vesicles, scaling and
thickening of the skin.
Section 12 - ECOLOGICAL INFORMATION
DO NOT discharge into sewer or waterways.
log Kow: 1.79
Koc: 26
Half-life (hr) air: 18.4
Half-life (hr) H2O surface water: 158.4-1776
Henry's atm m鲁 /mol: 7.19E-06
BCF: 3.2
Toxicity Fish: LC50(96)101.75-143mg/L
Toxicity invertebrate: LC50(96)95.69mg/L
Bioaccumulation: not sig
Degradation Biological: v sig
processes Abiotic: RxnOH*
Section 13 - DISPOSAL CONSIDERATIONS
路 Recycle wherever possible or consult manufacturer for recycling options.
路 Consult State Land Waste Authority for disposal.
路 Bury or incinerate residue at an approved site.
路 Recycle containers if possible, or dispose of in an authorised landfill.
路 Containers may still present a chemical hazard/ danger when empty.
路 Return to supplier for reuse/ recycling if possible.
Otherwise:
路 If container can not be cleaned sufficiently well to ensure that residuals do not
remain or if the container cannot be used to store the same product, then puncture
containers, to prevent re-use, and bury at an authorised landfill.
路 Where possible retain label warnings and MSDS and observe all notices pertaining to the
product.
Section 14 - TRANSPORTATION INFORMATION
HAZCHEM: None
NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS:UN, IATA,
IMDG
BUTYL GLYCOL ACETATE
(Chemwatch name: ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 12164
Issue Date: 12-Sep-2006 Version No:1
NC317TLP CD 2007/3 Page 12 of 12
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: S6
REGULATIONS
ethylene glycol monobutyl ether acetate (CAS: 112-07-2) is found on the following regulatory lists;
Australia Exposure Standards
Australia Inventory of Chemical Substances (AICS)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix E (Part 2)
IMO MARPOL 73/78 (Annex II) - List of Noxious Liquid Substances Carried in Bulk
International Council of Chemical Associations (ICCA) - High Production Volume List
OECD Representative List of High Production Volume (HPV) Chemicals
Section 16 - OTHER INFORMATION
Classification of the preparation and its individual components has drawn on official and
authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 12-Sep-2006
Print Date: 17-Dec-2007
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