CARMOISINE
(Chemwatch name: C.I. ACID RED 14)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 13859
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 1 of 9
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
CARMOISINE
SYNONYMS
C20-H12-N2-O7-S2.2Na, "1-naphthalenesulfonic acid, 4-hydroxy-3, 4'-azodi-, disodium
salt", "1-naphthalenesulfonic acid, 4-hydroxy-3, 4'-azodi-, disodium salt", "4-hydroxy
-3, 4'-diazo-1-naphthalenesulfonic acid, disodium salt", "4-hydroxy-3, 4'-diazo-1
-naphthalenesulfonic acid, disodium salt", "hydroxydiazonaphthalenesulfonic acid",
"disodium salt of 2-(4-sulfo-1-naphthylazo)-1-naphthol-4-sulfonic acid", "disodium salt
of 2-(4-sulfo-1-naphthylazo)-1-naphthol-4-sulfonic acid", "disodium 2-(4-sulfo-1
-naphthylazo)-1-naphthol-4-sulfonate", "disodium 2-(4-sulfo-1-naphthylazo)-1-naphthol-4
-sulfonate", "4-hydroxy-3, 4'-azodi-1-naphthalenesulfonic acid, disodium salt", "4
-hydroxy-3, 4'-azodi-1-naphthalenesulfonic acid, disodium salt", "4-hydroxy-3-((4-sulfo
-1-napthalenyl)azo)-1-naphthalenesulfonic acid. 2Na", "4-hydroxy-3-((4-sulfo-1
-napthalenyl)azo)-1-naphthalenesulfonic acid. 2Na", "2-(4-sulfo-1-naphthylazo)-1-naphthol
-4-sulfonic acid, disodium salt", "2-(4-sulfo-1-naphthylazo)-1-naphthol-4-sulfonic acid,
disodium salt", "2-(4-sulpho-1-naphthylazo)-1-naphthol-4-sulphonic acid, disodium salt",
"2-(4-sulpho-1-naphthylazo)-1-naphthol-4-sulphonic acid, disodium salt", "Acetacid Red
B", "Acid brilliant Rubine A2G Conc", "Acid Brilliant Rubine 2G", "Acid Brilliant Rubine
2GT", "Acid Chrome Blue BA", "Acid Chrome Blue BA-CF", "Acid Chrome Blue FBS", "Acid
Chrome Blue 2R", "Acid Fast Red FB", "Acid Red 2C", "Acid Rubine", "Acid Rubine Blue R",
"Atul Acid Crystal Red", "Airedale Carmoisine", "Amacid Carmoisine B", "Amacid Chrome
Rubin Extyra", "Atul Crystal Red", Azorubin, "Azo Rubin Extra, AF, LC, for food, LZ,
S, Specially Pure, XX", "Carmoisine, Aluminium Lake, BA, BA-CF, BSS, FU, GRN,
LAS, S, Supra, W, WS", "Certicol Carmoisine S", "Chrome Fast Blue 2R", "Chromotrop
FB", "C.I.Acid Red 14, disodium salt", "C.I.Food Red 3", "Crimson EMBL, 2EMBL", "Diadem
Chrome Blue G, R", E122, "Edicol Supra Carmoisine W, WS", "Eniacid Brilliant Rubine 3B"
, "Eriorubin B", "Eurocert Azorubine", "Ext D&C Red No. 10", "Extract D and C", "Red No.
10", "Fenazo Red C", "Food Red 5", "Fruit Red A Extra Yellowish Geigy", "HD Carmoisine,
Supra", "Hidacid Azo Rubine", "Hispacid Salt", "Java Rubine N", Karmesin, "Kenachrome
Blue 2R", "Kiton Crimson 2R", "Kiton Rubin R", "Lighthouse Chrome Blue 2R", "L. Red Z
3040", "Nacarat, A Export, Extra Pure A", NCI-C53849, "Neklacid Azorubine W, Rubine W"
, "Nylomine Acid Red P4B", "Omega Chrome Blue FB", "Pontacyl Rubine R", "Poloxal Red 2B",
"Red #14", "11959 Red", "Schultz NR 208", "Solar Rubine", "Solochrome Blue FB",
"Standacol Carmoisine", "Tertracid Red CA", "Tertochrome Blue FB", "Food Colour 122"
PRODUCT USE
Dyestuff used in histology. Food colouring and flavouring.
CARMOISINE
(Chemwatch name: C.I. ACID RED 14)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 13859
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 2 of 9
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Quantum Industrial Park
Dandenong South VIC 3175
Australia
Telephone: 1300 782 688
Emergency Tel: 1300 131 001
Fax: 1300 782 699
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
NON-HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to the Criteria of
NOHSC, and the ADG Code.
POISONS SCHEDULE
None
RISK SAFETY
Limited evidence of a carcinogenic effect*. Do not breathe dust.
* (limited evidence). Avoid contact with skin.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
C.I. Acid Red 14 3567-69-9 >98
Section 4 - FIRST AID MEASURES
SWALLOWED
路 Immediately give a glass of water.
路 First aid is not generally required. If in doubt, contact a Poisons Information Centre
or a doctor.
EYE
If this product comes in contact with eyes:
路 Wash out immediately with water.
路 If irritation continues, seek medical attention.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
CARMOISINE
(Chemwatch name: C.I. ACID RED 14)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 13859
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 3 of 9
Section 4 - FIRST AID MEASURES
SKIN
If skin contact occurs:
路 Immediately remove all contaminated clothing, including footwear.
路 Flush skin and hair with running water (and soap if available).
路 Seek medical attention in event of irritation.
INHALED
路 If dust is inhaled, remove from contaminated area.
路 Encourage patient to blow nose to ensure clear passage of breathing.
路 If irritation or discomfort persists seek medical attention.
NOTES TO PHYSICIAN
Treat symptomatically.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 Water spray or fog.
路 Foam.
路 Dry chemical powder.
路 BCF (where regulations permit).
路 Carbon dioxide.
FIRE FIGHTING
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Wear breathing apparatus plus protective gloves for fire only.
路 Prevent, by any means available, spillage from entering drains or water courses.
路 Use fire fighting procedures suitable for surrounding area.
路 DO NOT approach containers suspected to be hot.
路 Cool fire exposed containers with water spray from a protected location.
路 If safe to do so, remove containers from path of fire.
路 Equipment should be thoroughly decontaminated after use.
FIRE/EXPLOSION HAZARD
路 Solid which exhibits difficult combustion or is difficult to ignite.
路 Avoid generating dust, particularly clouds of dust in a confined or unventilated space
as dusts may form an explosive mixture with air, and any source of ignition, i.e.
flame or spark, will cause fire or explosion. Dust clouds generated by the fine
grinding of the solid are a particular hazard; accumulations of fine dust may burn
rapidly and fiercely if ignited.
路 Dry dust can also be charged electrostatically by turbulence, pneumatic transport,
pouring, in exhaust ducts and during transport.
路 Build-up of electrostatic charge may be prevented by bonding and grounding.
路 Powder handling equipment such as dust collectors, dryers and mills may require
additional protection measures such as explosion venting.
路 All movable parts coming in contact with this material should have a speed of less than
1-metre/sec.
Decomposes on heating and produces toxic fumes of sulfur oxides (SOx) and nitrogen oxides
(NOx).
FIRE INCOMPATIBILITY
Avoid contamination with strong oxidising agents, particularly peroxides, perchlorates,
etc. as violent decomposition / detonation may result.
HAZCHEM: None
CARMOISINE
(Chemwatch name: C.I. ACID RED 14)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 13859
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 4 of 9
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
路 Clean up all spills immediately.
路 Avoid contact with skin and eyes.
路 Wear protective clothing, gloves, safety glasses and dust respirator.
路 Use dry clean up procedures and avoid generating dust.
路 Sweep up or
路 Vacuum up (consider explosion-proof machines designed to be grounded during storage and
use).
路 Place in clean drum then flush area with water.
MAJOR SPILLS
路 Clear area of personnel and move upwind.
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Control personal contact by using protective equipment and dust respirator.
路 Prevent spillage from entering drains, sewers or water courses.
路 Avoid generating dust.
路 Sweep, shovel up. Recover product wherever possible.
路 Put residues in labelled plastic bags or other containers for disposal.
路 If contamination of drains or waterways occurs, advise emergency services.
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
Avoid generating and breathing dust.
路 Limit all unnecessary personal contact.
路 Wear protective clothing when risk of exposure occurs.
路 Use in a well-ventilated area.
路 Avoid contact with incompatible materials.
路 When handling, DO NOT eat, drink or smoke.
路 Keep containers securely sealed when not in use.
路 Avoid physical damage to containers.
路 Always wash hands with soap and water after handling.
路 Work clothes should be laundered separately.
路 Use good occupational work practice.
路 Observe manufacturer's storing and handling recommendations.
路 Atmosphere should be regularly checked against established exposure standards to ensure
safe working conditions are maintained.
SUITABLE CONTAINER
Glass container.
Plastic container.
路 Check that containers are clearly labelled.
Packaging as recommended by manufacturer.
STORAGE INCOMPATIBILITY
Avoid reaction with oxidising agents.
STORAGE REQUIREMENTS
路 Store in original containers.
CARMOISINE
(Chemwatch name: C.I. ACID RED 14)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 13859
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 5 of 9
Section 7 - HANDLING AND STORAGE
路 Keep containers securely sealed.
路 No smoking, naked lights or ignition sources.
路 Store in a cool, dry, well-ventilated area.
路 Store away from incompatible materials and foodstuff containers.
路 Protect containers against physical damage and check regularly for leaks.
路 Observe manufacturer's storing and handling recommendations.
_____________________________________________________
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
+ + + + + +
_____________________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA mg/m鲁
_________ _________ _____
Australia Exposure Standards C.I. Acid Red 14 (Inspirable 10
dust (Not specified))
MATERIAL DATA
These "dusts" have little adverse effect on the lungs and do not produce toxic effects or
organic disease. Although there is no dust which does not evoke some cellular response at
sufficiently high concentrations, the cellular response caused by P.N.O.C.s has the
following characteristics:
路 the architecture of the air spaces remain intact,
路 scar tissue (collagen) is not synthesised to any degree,
路 tissue reaction is potentially reversible.
Extensive concentrations of P.N.O.C.s may:
路 seriously reduce visibility,
路 cause unpleasant deposits in the eyes, ears and nasal passages,
路 contribute to skin or mucous membrane injury by chemical or mechanical action, per se,
or by the rigorous skin cleansing procedures necessary for their removal. [ACGIH]
This limit does not apply:
路 to brief exposures to higher concentrations
路 nor does it apply to those substances that may cause physiological impairment at lower
concentrations but for which a TLV has as yet to be determined.
This exposure standard applies to particles which
路 are insoluble or poorly soluble* in water or, preferably, in aqueous lung fluid (if
data is available) and
路 have a low toxicity (i.e.. are not cytotoxic, genotoxic, or otherwise chemically
reactive with lung tissue, and do not emit ionizing radiation, cause immune sensitization
, or cause toxic effects other than by inflammation or by a mechanism of lung overload).
PERSONAL PROTECTION
CARMOISINE
(Chemwatch name: C.I. ACID RED 14)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 13859
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 6 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EYE
路 Safety glasses with side shields
路 Chemical goggles.
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
Wear general protective gloves: i.e. Disposable polythene gloves or Cotton gloves or
Light weight rubber gloves, with Barrier cream preferably Safety footwear.
OTHER
路 Overalls.
路 Barrier cream
路 Eyewash unit.
RESPIRATOR
Protection Factor Half- Face Respirator Full- Face Respirator Powered Air Respirator
10 x ES P1 Air- line* -- PAPR- P1 -
50 x ES Air- line** P2 PAPR- P2
100 x ES - P3 -
Air- line* -
100+ x ES - Air- line** PAPR- P3
* - Negative pressure demand ** - Continuous flow.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
Use in a well-ventilated area.
路 Local exhaust ventilation is required where solids are handled as powders or crystals;
even when particulates are relatively large, a certain proportion will be powdered by
mutual friction.
路 Exhaust ventilation should be designed to prevent accumulation and recirculation of
particulates in the workplace.
路 If in spite of local exhaust an adverse concentration of the substance in air could
occur, respiratory protection should be considered. Such protection might consist of:
(a): particle dust respirators, if necessary, combined with an absorption cartridge;
(b): filter respirators with absorption cartridge or canister of the right type;
(c): fresh-air hoods or masks
CARMOISINE
(Chemwatch name: C.I. ACID RED 14)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 13859
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 7 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
路 Build-up of electrostatic charge on the dust particle, may be prevented by bonding and
grounding.
路 Powder handling equipment such as dust collectors, dryers and mills may require
additional protection measures such as explosion venting.
Air contaminants generated in the workplace possess varying "escape" velocities which, in
turn, determine the "capture velocities" of fresh circulating air required to efficiently
remove the contaminant.
Type of Contaminant: Air Speed:
direct spray, spray painting in shallow booths, 1- 2.5 m/s (200- 500 f/min.)
drum filling, conveyer loading, crusher dusts,
gas discharge (active generation into zone of
rapid air motion)
grinding, abrasive blasting, tumbling, high 2.5- 10 m/s (500- 2000 f/min.)
speed wheel generated dusts (released at high
initial velocity into zone of very high rapid
air motion).
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood- local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
source. The air velocity at the extraction fan, for example, should be a minimum of 4-10
m/s (800-2000 f/min) for extraction of crusher dusts generated 2 metres distant from the
extraction point. Other mechanical considerations, producing performance deficits within
the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or used.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Reddish- brown powder; mixes with water.
PHYSICAL PROPERTIES
Solid.
Mixes with water.
Molecular Weight: 502.44 Boiling Range (掳C): Not available
Melting Range (掳C): Not available Specific Gravity (water=1): Not available
Solubility in water (g/L): Miscible pH (as supplied): Not applicable
pH (1% solution): Not available Vapour Pressure (kPa): Negligible
Volatile Component (%vol): Negligible Evaporation Rate: Not applicable
CARMOISINE
(Chemwatch name: C.I. ACID RED 14)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 13859
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 8 of 9
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Relative Vapour Density (air=1): Not applicable Flash Point (掳C): Not available
Lower Explosive Limit (%): Not available Upper Explosive Limit (%): Not available
Autoignition Temp (掳C): Not available Decomposition Temp (掳C): Not available
State: Divided solid
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
路 Presence of incompatible materials.
路 Product is considered stable.
路 Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
The material may be mildly discomforting to the gastro-intestinal tract and may be
harmful if swallowed in large quantity.
Considered an unlikely route of entry in commercial/industrial environments.
EYE
The dust may produce eye discomfort causing smarting, pain and redness.
SKIN
The material may be. slightly discomforting to the skin.
INHALED
Not normally a hazard due to non-volatile nature of product.
The dust is. discomforting to the upper respiratory tract.
Persons with impaired respiratory function, airway diseases and conditions such as
emphysema or chronic bronchitis, may incur further disability if excessive concentrations
of particulate are inhaled.
CHRONIC HEALTH EFFECTS
Principal routes of exposure are usually by skin contact and inhalation of generated
dust.
As with any chemical product, contact with unprotected bare skin; inhalation of vapour,
mist or dust in work place atmosphere; or ingestion in any form, should be avoided by
observing good occupational work practice.
TOXICITY AND IRRITATION
TOXICITY IRRITATION
Intraperitoneal (rat) LD50: 900 mg/kg Nil Reported
Intravenous (rat) LD50: 800 mg/kg
The substance is classified by IARC as Group 3:
NOT classifiable as to its carcinogenicity to humans.
Evidence of carcinogenicity may be inadequate or limited in animal testing.
MATERIAL CARCINOGEN REPROTOXIN SENSITISER SKIN
_______________ ____________ __________ __________ __________
C.I. Acid Red 14 IARC:3
CARCINOGEN
CARMOISINE
(Chemwatch name: C.I. ACID RED 14)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 13859
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 9 of 9
Section 11 - TOXICOLOGICAL INFORMATION
IARC: International Agency for Research on Cancer (IARC) Carcinogens: C.I. Acid Red 14
Category: 3
Section 12 - ECOLOGICAL INFORMATION
No data for C.I. Acid Red 14.
Section 13 - DISPOSAL CONSIDERATIONS
路 Consult manufacturer for recycling options and recycle where possible .
路 Consult State Land Waste Management Authority for disposal.
路 Incinerate residue at an approved site.
路 Recycle containers if possible, or dispose of in an authorised landfill.
Section 14 - TRANSPORTATION INFORMATION
HAZCHEM: None
NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS:UN, IATA,
IMDG
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: None
REGULATIONS
C.I. Acid Red 14 (CAS: 3567-69-9) is found on the following regulatory lists;
Australia Exposure Standards
Australia Inventory of Chemical Substances (AICS)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix E (Part 2)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix F (Part 3)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Schedule 6
International Agency for Research on Cancer (IARC) Carcinogens
Section 16 - OTHER INFORMATION
Classification of the preparation and its individual components has drawn on official and
authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 12-May-2005
Print Date: 17-Dec-2007
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