CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 1 of 17
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
CREOSOTE OIL 32
SYNONYMS
"beechwood creosote", "liquid pitch oil", "wood creosote", creasote
PROPER SHIPPING NAME
TOXIC LIQUID, ORGANIC, N.O.S.
PRODUCT USE
A liquid obtained by distillation of wood tars. used as an antiseptic, expectorant,
gastric sedative, deodorant, gastrointestinal antiseptic, wood preservative; in veterinary
use as an antiseptic parasiticide.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Quantum Industrial Park
Dandenong South VIC 3175
Australia
Telephone: 1300 782 688
Emergency Tel: 1300 131 001
Fax: 1300 782 699
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 2 of 17
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. DANGEROUS GOODS. According to the Criteria of NOHSC,
and the ADG Code.
POISONS SCHEDULE
S2
RISK SAFETY
Irritating to skin. Do not breathe gas/ fumes/ vapour/ spray.
Inhalation skin contact and/or ingestion may Avoid contact with eyes.
produce health damage*.
Cumulative effects may result following Wear suitable protective clothing.
exposure*.
May produce discomfort of the eyes and Use only in well ventilated areas.
respiratory tract*.
Limited evidence of a carcinogenic effect*. Keep container in a well ventilated place.
* (limited evidence). To clean the floor and all objects contaminated
by this material use water and detergent.
Keep container tightly closed.
Keep away from food drink and animal feeding
stuffs.
Take off immediately all contaminated clothing.
In case of contact with eyes rinse with plenty
of water and contact Doctor or Poisons
Information Centre.
If swallowed IMMEDIATELY contact Doctor or
Poisons Information Centre (show this container
or label).
This material and its container must be disposed
of as hazardous waste.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
Consists mainly of
guaiacol 90-05-1 >5
cresols 1319-77-3
creosol 93-51-6
benz[a]pyrene 50-32-8
benz[a]anthracene 56-55-3
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 3 of 17
Section 4 - FIRST AID MEASURES
SWALLOWED
For advice, contact a Poisons Information Centre or a doctor.
路 If swallowed do NOT induce vomiting.
路 If vomiting occurs, lean patient forward or place on left side (head-down position, if
possible) to maintain open airway and prevent aspiration.
路 Observe the patient carefully.
路 Never give liquid to a person showing signs of being sleepy or with reduced awareness;
i.e. becoming unconscious
路 Give water to rinse out mouth, then provide liquid slowly and as much as casualty can
comfortably drink.
路 Seek medical advice.
EYE
If this product comes in contact with the eyes:
路 Immediately hold eyelids apart and flush the eye continuously with running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 Continue flushing until advised to stop by the Poisons Information Centre or a doctor,
or for at least 15 minutes.
路 Transport to hospital or doctor without delay.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
SKIN
If spilt on skin:
路 Remove contaminated clothing, swab repeatedly with glycerin, PEG (polyethylene glycol),
or PEG/ methylated spirit mixture or if necessary with methylated spirit alone*
路 Contamination of skin with phenol and some of its derivatives may produce rapid
collapse and death.
路 After skin contamination, keep patient under observation for at least 24-48 hours.
路 Phenol-decontaminating fluid is more effective than water in removing phenol from the
skin and retarding absorption; olive oil or vegetable oil may also be used; do not use
mineral oil.
路 Alcohols* (methylated spirit, for example) may enhance absorption and their use alone
may be ill-advised; some authorities however continue to advise the use of such
treatment.
路 Rapid water dilution of phenol burns may increase systemic absorption by decreasing the
extent of the coagulum and thus allowing greater absorption (1).
(1) Ellenhorn and Barceloux: Medical Toxicology: Diagnosis and Treatment of Human
Poisoning.
INHALED
路 If fumes or combustion products are inhaled remove from contaminated area.
路 Lay patient down. Keep warm and rested.
路 Prostheses such as false teeth, which may block airway, should be removed, where
possible, prior to initiating first aid procedures.
路 Apply artificial respiration if not breathing, preferably with a demand valve
resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary.
路 Transport to hospital, or doctor, without delay.
NOTES TO PHYSICIAN
For acute or short term repeated exposures to phenols/ cresols:
路 Phenol is absorbed rapidly through lungs and skin. [Massive skin contact may result in
collapse and death]*
路 [Ingestion may result in ulceration of upper respiratory tract; perforation of
oesophagus and/or stomach, with attendant complications, may occur. Oesophageal stricture
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 4 of 17
Section 4 - FIRST AID MEASURES
may occur.]*
路 An initial excitatory phase may present. Convulsions may appear as long as 18 hours
after ingestion. Hypotension and ventricular tachycardia that require vasopressor and
antiarrhythmic therapy, respectively, can occur.
路 Respiratory arrest, ventricular dysrhythmias, seizures and metabolic acidosis may
complicate severe phenol exposures so the initial attention should be directed towards
stabilisation of breathing and circulation with ventilation, intubation, intravenous
lines, fluids and cardiac monitoring as indicated.
路 [Vegetable oils retard absorption; do NOT use paraffin oils or alcohols. Gastric lavage
, with endotracheal intubation, should be repeated until phenol odour is no longer
detectable; follow with vegetable oil. A saline cathartic should then be given.]*
ALTERNATIVELY: Activated charcoal (1g/kg) may be given. A cathartic should be given after
oral activated charcoal.
路 Severe poisoning may require slow intravenous injection of methylene blue to treat
methaemoglobinaemia.
路 [Renal failure may require haemodialysis.]*
路 Most absorbed phenol is biotransformed by the liver to ethereal and glucuronide
sulfates and is eliminated almost completely after 24 hours. [Ellenhorn and Barceloux:
Medical Toxicology] *[Union Carbide]
BIOLOGICAL EXPOSURE INDEX - BEI
These represent the determinants observed in specimens collected from a healthy worker
who has been exposed to the Exposure Standard (ES or TLV):
Determinant Index Sampling Time Comments
1. Total phenol in 250 mg/gm creatinine End of shift B, NS
blood
B: Background levels occur in specimens collected from subjects NOT exposed
NS: Non-specific determinant; also seen in exposure to other materials.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 Foam.
路 Dry chemical powder.
路 BCF (where regulations permit).
路 Carbon dioxide.
路 Water spray or fog - Large fires only.
FIRE FIGHTING
Alert Fire Brigade and tell them location and nature of hazard.
路 Wear full body protective clothing with breathing apparatus.
路 Prevent, by any means available, spillage from entering drains or water course.
路 Consider evacuation (or protect in place).
Use water delivered as a fine spray to control the fire and cool adjacent area.
DO NOT approach containers suspected to be hot.
Cool fire exposed containers with water spray from a protected location.
If safe to do so, remove containers from path of fire.
FIRE/EXPLOSION HAZARD
路 Combustible.
路 Slight fire hazard when exposed to heat or flame.
路 Heating may cause expansion or decomposition leading to violent rupture of containers.
路 On combustion, may emit toxic fumes of carbon monoxide (CO).
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 5 of 17
Section 5 - FIRE FIGHTING MEASURES
路 May emit acrid smoke.
路 Mists containing combustible materials may be explosive.
FIRE INCOMPATIBILITY
Avoid contamination with strong oxidising agents, particularly peroxides, perchlorates,
etc. as violent decomposition / detonation may result.
HAZCHEM: 2X
Personal Protective Equipment
Gas tight chemical resistant suit.
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
Clean up all spills immediately.
Clear area of personnel.
Wear protective clothing, impervious gloves and safety glasses.
Avoid breathing vapours and contact with skin and eyes.
Wipe up and absorb small quantities with vermiculite or other absorbent material.
Place in suitable containers for disposal.
Wash spill area with detergent and water.
MAJOR SPILLS
Clear area of personnel and move upwind.
Alert Fire Brigade and tell them location and nature of hazard.
路 Wear full body protective clothing with breathing apparatus.
路 Prevent, by any means available, spillage from entering drains or water courses.
路 Consider evacuation (or protect in place).
No smoking, naked lights or ignition sources. Increase ventilation.
Stop leak if safe to do so.
Contain spill with sand, earth or vermiculite.
Collect recoverable product into labelled containers for recycling.
Absorb remaining product with sand, earth or vermiculite.
Collect, using a spark-free shovel, and seal in labelled drums for disposal.
Wash area down with large quantity of water and prevent runoff into drains.
If contamination of drains or waterways occurs, advise emergency services.
After clean up operations, decontaminate and launder all protective clothing and
equipment before storing and re-using.
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
Use good occupational work practice. Observe manufacturer's storing and handling
recommendations.
Avoid all personal contact, including inhalation.
Avoid generating and breathing mist and vapour.
Wear protective clothing when risk of exposure occurs.
Avoid smoking, naked lights, heat or ignition sources.
Use in a well-ventilated area.
Decant in a well-ventilated area or under an exhaust hood.
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 6 of 17
Section 7 - HANDLING AND STORAGE
Avoid contact with incompatible materials.
Handle and open container with care.
When handling, DO NOT eat, drink or smoke.
Avoid physical damage to containers.
Always wash hands with soap and water after handling. Work clothes should be laundered
separately.
SUITABLE CONTAINER
Packaging as recommended by manufacturer.
路 Check that containers are clearly labelled.
Glass container.
Polyethylene or polypropylene container.
Metal can.
STORAGE INCOMPATIBILITY
Avoid reaction with oxidising agents, bases and strong reducing agents.
Incompatible with ferric, cupric, gold and silver salts, acacia, albumin,
camphor, menthol, and chloral hydrate.
STORAGE REQUIREMENTS
Observe manufacturer's storing and handling recommendations.
Store in original containers.
Keep containers securely sealed.
No smoking, naked lights, heat or ignition sources.
Store in a well-ventilated area.
Store in a cool area and away from sunlight.
Store away from foodstuff containers.
Store away from incompatible materials.
Keep storage area free of debris, waste and combustibles.
Store in an upright position.
Protect containers against physical damage.
Check regularly for spills and leaks.
_____________________________________________________
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
+ X + X 0 +
_____________________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA ppm TWA mg/m鲁
_________ _________ _____ _____
Australia Exposure cresols (Cresol, all 5 22
Standards isomers)
Australia Exposure benz[a]anthracene 10
Standards (Inspirable dust (Not
specified))
The following materials had no OELs on our records
鈥? creosote, wood: CAS:8021- 39- 4 CAS:8013- 10- 3
鈥? guaiacol: CAS:90- 05- 1
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 7 of 17
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
鈥? creosol: CAS:93- 51- 6
EMERGENCY EXPOSURE LIMITS
Material Revised IDLH Value (mg/m3) Revised IDLH Value (ppm)
cresols 250 [Unch]
MATERIAL DATA
Not available. Refer to individual constituents.
INGREDIENT DATA
CREOSOL:
CRESOLS:
GUAIACOL:
Exposure limits with "skin" notation indicate that vapour and liquid may be absorbed
through intact skin. Absorption by skin may readily exceed vapour inhalation exposure.
Symptoms for skin absorption are the same as for inhalation. Contact with eyes and mucous
membranes may also contribute to overall exposure and may also invalidate the exposure
standard.
GUAIACOL:
CEL TWA: 5 ppm; 25.5 mg/m3 (skin) (all isomers) (compare TLV-TWA cresol)
The recommended TLV-TWA takes account of the closely analogous to the
toxic action of phenol
Systemic absorption by all routes may induce convulsions with damage to
the lungs and central nervous system. Exposure at or below the recommended
TLV-TWA is thought to protect the worker from respiratory, cardiovascular,
hepatic, renal and neurological toxicity. Workers or volunteers exposed
to phenol at or below 5.2 ppm have experienced no ill-effects. Because
phenol as a vapour, liquid or solid can penetrate the skin causing systemic
effects, a skin notation is considered necessary. Although ACGIH has not
recommended a STEL it is felt that ACGIH excursion limits (15 ppm limited
to a total duration of 30 minutes with brief excursions limited to no more
than 25 ppm) and NIOSH Ceiling values (15 minutes at 15.6 ppm) are
sufficiently similar so as to provide the same margin of safety.
CRESOLS:
Concentrations of cresol in air as low as 5 ppm are easily recognised.
The recommended TLV-TWA takes account of the closely analogous to the
toxic action of phenol
Systemic absorption by all routes may induce convulsions with damage to
the lungs and central nervous system. Exposure at or below the recommended
TLV-TWA is thought to protect the worker from respiratory, cardiovascular,
hepatic, renal and neurological toxicity. Workers or volunteers exposed
to phenol at or below 5.2 ppm have experienced no ill-effects. Because
phenol as a vapour, liquid or solid can penetrate the skin causing systemic
effects, a skin notation is considered necessary. Although ACGIH has not
recommended a STEL it is felt that ACGIH excursion limits (15 ppm limited
to a total duration of 30 minutes with brief excursions limited to no more
than 25 ppm) and NIOSH Ceiling values (15 minutes at 15.6 ppm) are
sufficiently similar so as to provide the same margin of safety.
CREOSOL:
CEL TWA: 5 ppm; 22 mg/m3 (skin) (all isomers) (compare TLV-TWA cresol)
The recommended TLV-TWA takes account of the closely analogous to the
toxic action of phenol
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 8 of 17
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
Systemic absorption by all routes may induce convulsions with damage to
the lungs and central nervous system. Exposure at or below the recommended
TLV-TWA is thought to protect the worker from respiratory, cardiovascular,
hepatic, renal and neurological toxicity. Workers or volunteers exposed
to phenol at or below 5.2 ppm have experienced no ill-effects. Because
phenol as a vapour, liquid or solid can penetrate the skin causing systemic
effects, a skin notation is considered necessary. Although ACGIH has not
recommended a STEL it is felt that ACGIH excursion limits (15 ppm limited
to a total duration of 30 minutes with brief excursions limited to no more
than 25 ppm) and NIOSH Ceiling values (15 minutes at 15.6 ppm) are
sufficiently similar so as to provide the same margin of safety.
BENZ[A]PYRENE:
No exposure limits set by NOHSC or ACGIH.
CEL TWA: 0.005 mg/m3; STEL 0.03 mg/m3 (skin) [compare Swedish OEL]
NOTE: OEL-STEL (Russia): 0.00015 mg/m3
Epidemiological and animal studies indicate the need to establish
rigorous control standards for B[a]P as increased exposures are harmful.
As little as 0.05 mg can initiate tumours in experimental animals and
0.1uM (25 ug/l) is toxic to cultured human hepatocytes. It is estimated
that millions of people living near coke ovens are exposed to 100 ug B[a]P
daily. Because small repeated doses are more effective in initiating
tumours than single administrations and because people are probably
exposed to other synergistically acting pollutants they are exceeding safe
levels of exposure. The Russian legislation concedes that the OEL-STEL is
not considered safe but, rather, unavoidable.
PERSONAL PROTECTION
EYE
路 Safety glasses with side shields.
路 Chemical goggles.
路 Full face shield.
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
Nitrile gloves.
Impervious gloves.
Safety footwear.
#76a-p()
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 9 of 17
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
OTHER
Overalls.
路 Impervious protective clothing.
路 Eyewash unit.
Ensure there is ready access to a safety shower.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
General exhaust is adequate under normal operating conditions. Local exhaust ventilation
may be required in specific circumstances. If risk of overexposure exists, wear approved
respirator. Correct fit is essential to obtain adequate protection. Provide adequate
ventilation in warehouse or closed storage areas. Air contaminants generated in the
workplace possess varying "escape" velocities which, in turn, determine the "capture
velocities" of fresh circulating air required to effectively remove the contaminant.
Type of Contaminant: Air Speed:
solvent, vapours, degreasing etc., evaporating 0.25- 0.5 m/s (50- 100 f/min)
from tank (in still air).
aerosols, fumes from pouring operations, 0.5- 1 m/s (100- 200 f/min.)
intermittent container filling, low speed
conveyer transfers, welding, spray drift,
plating acid fumes, pickling (released at low
velocity into zone of active generation)
direct spray, spray painting in shallow booths, 1- 2.5 m/s (200- 500 f/min.)
drum filling, conveyer loading, crusher dusts,
gas discharge (active generation into zone of
rapid air motion)
grinding, abrasive blasting, tumbling, high 2.5- 10 m/s (500- 2000 f/min.)
speed wheel generated dusts (released at high
initial velocity into zone of very high rapid
air motion).
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only.
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood- local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
source. The air velocity at the extraction fan, for example, should be a minimum of 1-2
m/s (200-400 f/min) for extraction of solvents generated in a tank 2 meters distant from
the extraction point. Other mechanical considerations, producing performance deficits
within the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or used.
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 10 of 17
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Colourless to yellowish oily liquid with smokey odour and caustic burning taste; does not
mix well with water Solubilities (mg/ml, 23 deg. C): DMSO =/> 100, 95% ethanol =/> 100,
acetone => 100. Other solvents (parts): glycerol 150- 200, glacial acetic acid, 150- 200.
Miscible with chloroform, ether, oils. Sensitive on exposure to air. Solutions in water,
DMSO, 95% ethanol or acetone should be stable for 24 hours.
PHYSICAL PROPERTIES
Liquid.
Does not mix with water.
Sinks in water.
Molecular Weight: Not applicable Boiling Range (掳C): <- 20
Melting Range (掳C): >203 Specific Gravity (water=1): 1.076 (25 C)
Solubility in water (g/L): Partly miscible pH (as supplied): Not applicable
pH (1% solution): Not available Vapour Pressure (kPa): 0.0146 @ 25 C
Volatile Component (%vol): Not available. Evaporation Rate: Not available
Relative Vapour Density (air=1): >4 Flash Point (掳C): 74
Lower Explosive Limit (%): Not available Upper Explosive Limit (%): Not available
Autoignition Temp (掳C): Not available. Decomposition Temp (掳C): Not available.
State: Liquid
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
Presence of incompatible materials.
Storage in unsealed containers.
Presence of heat source and direct sunlight.
Product is considered stable under normal handling conditions.
Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
The liquid is. toxic and may be discomforting to the gastro-intestinal tract.
Considered an unlikely route of entry in commercial/industrial environments.
Ingestion of creosotes or creosote-containing products may produce nausea, vomiting,
abdominal pain, salivation, dizziness, breathing difficulties, thready pulse, loss of
pupillary reflexes, cyanosis, convulsions, low blood pressure and central nervous system
stimulation.
Some phenol derivatives can cause damage to the digestive system. If absorbed, profuse
sweating, thirst, nausea, vomiting, diarrhoea, cyanosis, restlessness, stupor, low blood
pressure, gasping, abdominal pain, anaemia, convulsions, coma and lung swelling can
happen followed by pneumonia. There may be respiratory failure and kidney damage.
Chemical burns, seizures and irregular heartbeat may result.
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 11 of 17
Section 11 - TOXICOLOGICAL INFORMATION
EYE
The liquid is discomforting to the eyes and is capable of causing a mild, temporary
redness of the conjunctiva (similar to wind-burn), temporary impairment of vision and/ or
other transient eye damage/ ulceration.
Eye contact with creosotes or creosote-containing preparations may cause conjunctivitis,
keratitis, abrasion of cornea and scarring.
Some phenol derivatives may produce mild to severe eye irritation with redness, pain and
blurred vision. Permanent eye injury may occur; recovery may also be complete or partial.
The material may be irritating to the eye, with prolonged contact causing inflammation.
Repeated or prolonged exposure to irritants may produce conjunctivitis.
SKIN
The liquid is extremely discomforting to the skin.
Prolonged exposure may cause chemical burns.
Toxic effects may result from skin absorption.
Skin contact may cause redness or greyish-yellow to bronze pigmentation, pimples,
blisters, and ulcers. Photosensitivity may result in severe sunburn on subsequent
exposure to ultraviolet light with an increased risk of skin cancer.
Phenol and its derivatives can cause severe skin irritation if contact is maintained, and
can be absorbed to the skin affecting the cardiovascular and central nervous system.
Effects include sweating, intense thirst, nausea and vomiting, diarrhoea, cyanosis,
restlessness, stupor, low blood pressure, hyperventilation, abdominal pain, anaemia,
convulsions, coma, lung swelling followed by pneumonia. Respiratory failure and kidney
damage may follow.
Exposure to this product can cause sensitization of skin under sunlight. The product can
reach the skin via the bloodstream if either swallowed or ingested. Swelling and redness
are common; blistering may also occur. The skin may become warm and itchy. There may also
be discolouration. Phototoxicity is a non-allergic condition and severity depends on the
concentration of the offending chemical and the amount of radiation of particular
wavelengths, usually in the UV spectrum. Inflammation develops on uncovered areas such as
the hands and face; covered areas are usually spared. This is usually more like sunburn
than an eczema. Coal tar products often cause phototoxic reactions. Phototoxic compounds
may show their nature either by generating free radicals or reacting directly with target
molecules under UV light.
The material may cause severe skin irritation after prolonged or repeated exposure and
may produce on contact skin redness, swelling, the production of vesicles, scaling and
thickening of the skin. Repeated exposures may produce severe ulceration.
INHALED
The vapour is. toxic and discomforting to the upper respiratory tract and may be harmful.
Inhalation of creosotes or creosote-containing products may produce headache, dizziness
and irregular breathing. Severe exposures may cause confusion, collapse and coma.
If phenols are absorbed via the lungs, systemic effects may occur affecting the
cardiovascular and nervous systems. Inhalation can result in profuse perspiration,
intense thirst, nausea, vomiting, diarrhoea, cyanosis, restlessness, stupor, falling
blood pressure, hyperventilation, abdominal pain, anaemia, convulsions, coma, swelling
and inflammation of the lung. This is followed by respiratory failure and kidney damage.
Phenols also cause loss of sensation and general depression at high concentrations. The
toxicities of phenol derivatives vary.
CHRONIC HEALTH EFFECTS
Principal routes of exposure are by accidental skin and eye contact and by inhalation of
vapours especially at higher temperatures.
Patients receiving tar ointments for various skin complaints have developed skin cancer
in a number of case reports. There is evidence that these ointments can cause mutations.
Patent-fuel workers and workers exposed to coal tars or coal-tar pitches have developed
cancer of the skin and scrotum. Studies have shown that workers exposed to coal tar fumes
in coal gasification and coke production have a higher rate of developing lung cancer. A
study in US roofers indicated an increased risk for cancer of the lung and suggested
increased risks for cancer of the mouth, throat, oesophagus, stomach, skin and bladder
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 12 of 17
Section 11 - TOXICOLOGICAL INFORMATION
and for leukaemia. One study showed a small increase in bladder cancer rates in coal tar
distillers and patent-fuel workers.
Coal tar derived grades of creosote contain coal tar pitch volatiles and polycyclic
aromatic hydrocarbons (PAHs) which are known to cause cancer. They are the chief
ingredients of tar-derived creosote.
Thermal and creosote dip-treatment workers in wood-treatment plants may have consistent
potential inhalation exposures to creosote and these PAHs. Although PAHs are normally not
absorbed through uninjured skin, it might be absorbed with other chemicals or through
broken skin.
Long-term exposure to phenol derivatives can cause skin inflammation, loss of appetite
and weight, weakness, muscle aches and pain, liver damage, dark urine, loss of nails,
skin eruptions, diarrhoea, nervous disorders with headache, salivation, fainting,
discolouration of the skin and eyes, vertigo and mental disorders, and damage to the
liver and kidneys.
TOXICITY AND IRRITATION
No significant acute toxicological data identified in literature search.
Changes in brain weight, changes in bladder weight, changes in liver
weight, changes in tubules, changes in ovarian weight recorded.
GUAIACOL:
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (rabbit) LD50: 725 mg/kg Skin (rabbit):500 mg/24h- SEVERE
Dermal (rabbit) LD50: 4600 mg/kg Eye (rabbit): 5 mg - Mild
Oral (human) LDLo: 43 mg/kg
CRESOLS:
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (man) TDLo: 177 mg/kg Nil Reported
Oral (rat) LD50: 1454 mg/kg
Dermal (rabbit) LD50: 2000 mg/kg
Asthma-like symptoms may continue for months or even years after exposure to the material
ceases. This may be due to a non-allergenic condition known as reactive airways
dysfunction syndrome (RADS) which can occur following exposure to high levels of highly
irritating compound. Key criteria for the diagnosis of RADS include the absence of
preceding respiratory disease, in a non-atopic individual, with abrupt onset of
persistent asthma-like symptoms within minutes to hours of a documented exposure to the
irritant. A reversible airflow pattern, on spirometry, with the presence of moderate to
severe bronchial hyperreactivity on methacholine challenge testing and the lack of
minimal lymphocytic inflammation, without eosinophilia, have also been included in the
criteria for diagnosis of RADS. RADS (or asthma) following an irritating inhalation is an
infrequent disorder with rates related to the concentration of and duration of exposure
to the irritating substance. Industrial bronchitis, on the other hand, is a disorder that
occurs as result of exposure due to high concentrations of irritating substance (often
particulate in nature) and is completely reversible after exposure ceases. The disorder
is characterised by dyspnea, cough and mucus production.
CREOSOL:
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Intravenous (mouse) LD50: 76 mg/kg Nil Reported
BENZ[A]PYRENE:
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Subcutaneous (rat) LD50: 50 mg/kg Skin (mouse): 0.014 mg - Mild
Exposure to the material for prolonged periods may cause physical defects in the
developing embryo (teratogenesis).
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 13 of 17
Section 11 - TOXICOLOGICAL INFORMATION
WARNING: This substance has been classified by the IARC as Group 2A: Probably
Carcinogenic to Humans.
Tenth Annual Report on Carcinogens: Substance anticipated to be Carcinogen
[National Toxicology Program: U.S. Dep. of Health & Human Services 2002].
BENZ[A]ANTHRACENE:
TOXICITY IRRITATION
Intravenous (rat) LD50: > 200 mg/kg Nil Reported
WARNING: This substance has been classified by the IARC as Group 2A: Probably
Carcinogenic to Humans.
Tenth Annual Report on Carcinogens: Substance anticipated to be Carcinogen
[National Toxicology Program: U.S. Dep. of Health & Human Services 2002].
MATERIAL CARCINOGEN REPROTOXIN SENSITISER SKIN
_______________ ____________ __________ __________ __________
benz[a]pyrene IARC:1 NOHSC NTPB
benz[a]anthracene IARC:2B NTPB
CARCINOGEN
IARC: International Agency for Research on Cancer (IARC) Carcinogens: benz[a]pyrene
Category: 1
CARCINOGEN
NOHSC: Australia Exposure Standards - Carcinogens: benz[a]pyrene
Carcinogen Category: 2
CARCINOGEN
NTPB: US National Toxicology Program (NTP) 11th Report Part B. Reasonably Anticipated
to be a Human Carcinogen: benz[a]pyrene Category:
CARCINOGEN
IARC: International Agency for Research on Cancer (IARC) Carcinogens: benz[a]anthracene
Category: 2B
CARCINOGEN
NTPB: US National Toxicology Program (NTP) 11th Report Part B. Reasonably Anticipated
to be a Human Carcinogen: benz[a]anthracene Category:
Section 12 - ECOLOGICAL INFORMATION
Marine Pollutant:Not Determined
No data for creosote, wood.
Refer to data for ingredients, which follows:
GUAIACOL:
log Pow (Verschueren 1983): 1.31/2.53
BOD5: 68%
BOD20: 100%
COD: 2.06
log Kow: 1.13-2.53
BOD 5 if unstated: 68%
COD: 100%
ThOD: 2.06
Bioacculmulation: not sig
Degradation Biological: by soil microflora >64 days
CRESOLS:
Half- life Soil - High (hours): 696
Half- life Soil - Low (hours): 1
Half- life Air - High (hours): 16
Half- life Air - Low (hours): 1.1
Half- life Surface water - High (hours): 696
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 14 of 17
Section 12 - ECOLOGICAL INFORMATION
Half- life Surface water - Low (hours): 1
Half- life Ground water - High (hours): 1176
Half- life Ground water - Low (hours): 2
Aqueous biodegradation - Aerobic - High (hours): 696
Aqueous biodegradation - Aerobic - Low (hours): 1
Aqueous biodegradation - Anaerobic - High (hours): 1176
Aqueous biodegradation - Anaerobic - Low (hours): 240
Aqueous biodegradation - Removal secondary treatment - High (hours): 99.00%
Photolysis maximum light absorption - High (nano- m): 282
Photolysis maximum light absorption - Low (nano- m): 238
Photooxidation half- life air - High (hours): 16
Photooxidation half- life air - Low (hours): 1.1
Environmental toxicity is a function of the n-octanol/ water partition coefficient (log
Pow, log Kow). Phenols with log Pow >7.4 are expected to exhibit low toxicity to aquatic
organisms. However the toxicity of phenols with a lower log Pow is variable, ranging from
low toxicity (LC50 values >100 mg/l) to highly toxic (LC50 values <1 mg/l) dependent on
log Pow, molecular weight and substitutions on the aromatic ring. Dinitrophenols are more
toxic than predicted from QSAR estimates. Hazard information for these groups is not
generally available.
DO NOT discharge into sewer or waterways.
BENZ[A]PYRENE:
log Kow (Sangster 1997): 6.35
Half- life Soil - High (hours): 12720
Half- life Soil - Low (hours): 1368
Half- life Air - High (hours): 1.1
Half- life Air - Low (hours): 0.37
Half- life Surface water - High (hours): 1.1
Half- life Surface water - Low (hours): 0.37
Half- life Ground water - High (hours): 25440
Half- life Ground water - Low (hours): 2736
Aqueous biodegradation - Aerobic - High (hours): 12720
Aqueous biodegradation - Aerobic - Low (hours): 1368
Aqueous biodegradation - Anaerobic - High (hours): 50880
Aqueous biodegradation - Anaerobic - Low (hours): 5472
Aqueous photolysis half- life - High (hours): 1.1
Aqueous photolysis half- life - Low (hours): 0.37
Aqueous photolysis half- life - High (hours): 1.1
Aqueous photolysis half- life - Low (hours): 0.37
Photooxidation half- life water - High (hours): 10349
Photooxidation half- life water - Low (hours): 207
Photooxidation half- life air - High (hours): 4.28
Photooxidation half- life air - Low (hours): 0.428
log Kow : 5.78-6.74
log Koc: 4-8.3
Koc: 18000-52000
Half-life (hr) air: 0.37-1.1
Half-life (hr) H2O surface water: 0.37-300
Half-life (hr) H2O ground: 2736-25440
Half-life (hr) soil: 48-50400
Henry's Pa m鲁 /mol: 0.0079-0.81
BCF: 920-13000
Log BCF: 1.14-6.95
Toxicity Fish: LD50(96)<1ppm
Bioacculmulation: sig
Degradation Biological: sig
processes Abiotic: fast photol & oxid, no hydrol
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 15 of 17
Section 12 - ECOLOGICAL INFORMATION
BENZ[A]ANTHRACENE:
Half- life Soil - High (hours): 16320
Half- life Soil - Low (hours): 2448
Half- life Air - High (hours): 3
Half- life Air - Low (hours): 1
Half- life Surface water - High (hours): 3
Half- life Surface water - Low (hours): 1
Half- life Ground water - High (hours): 32640
Half- life Ground water - Low (hours): 4896
Aqueous biodegradation - Aerobic - High (hours): 16230
Aqueous biodegradation - Aerobic - Low (hours): 2448
Aqueous biodegradation - Anaerobic - High (hours): 65280
Aqueous biodegradation - Anaerobic - Low (hours): 9792
Aqueous photolysis half- life - High (hours): 3
Aqueous photolysis half- life - Low (hours): 1
Photolysis maximum light absorption - High (nano- m): 386
Photolysis maximum light absorption - Low (nano- m): 222
Aqueous photolysis half- life - High (hours): 3
Aqueous photolysis half- life - Low (hours): 1
Photooxidation half- life water - High (hours): 3.85E+03
Photooxidation half- life water - Low (hours): 77
Photooxidation half- life air - High (hours): 8.01
Photooxidation half- life air - Low (hours): 0.801
Water solubility (g/l): 4.04
log Kow (Prager 1995): 5.61
log Kow (Sangster 1997): 5.91
log Kow : 5.48-5.91
log Koc: 4-7.3
Half-life (hr) air: 0.4-3
Half-life (hr) H2O surface water: 1.0-3.0
Half-life (hr) H2O ground: 0.34-32640
Half-life (hr) soil: 96-16320
Henry's Pa m鲁 /mol: 0.092-0.813
BCF: 20-54
Log BCF: 4.0-5.0
Bioacculmulation: sig in oysters
Anaerobic effects: slow degrad.
Degradation Biological: not observed
processes Abiotic: fast photol & oxid, no hydrol
Section 13 - DISPOSAL CONSIDERATIONS
Recycle wherever possible.
Consult manufacturer for recycling options.
Consult State Land Waste Management Authority for disposal.
Incinerate residue at an approved site.
Decontaminate empty containers.
Ensure damaged or non-returnable containers are decontaminated before disposal.
Recycle containers if possible, or dispose of in an authorised landfill.
Section 14 - TRANSPORTATION INFORMATION
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 16 of 17
Section 14 - TRANSPORTATION INFORMATION
Labels Required: TOXIC
HAZCHEM: 2X
UNDG:
Dangerous Goods Class: 6.1 Subrisk: None
UN Number: 2810 Packing Group: III
Shipping Name:TOXIC LIQUID, ORGANIC, N.O.S.
Air Transport IATA:
ICAO/IATA Class: 6.1 ICAO/IATA Subrisk: None
UN/ID Number: 2810 Packing Group: III
Special provisions: A3谩A4谩A137
Shipping Name: TOXIC LIQUID, ORGANIC N.O.S.
Maritime Transport IMDG:
IMDG Class: 6.1 IMDG Subrisk: None
UN Number: 2810 Packing Group: III
EMS Number: F- A, S- A Special provisions: 223 274 944
Marine Pollutant: Not Determined
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: S2
REGULATIONS
creosote, wood (CAS: 8021-39-4) is found on the following regulatory lists;
Australia Inventory of Chemical Substances (AICS)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix E (Part 2)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix F (Part 3)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Schedule 6
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Schedule 7
IMO MARPOL 73/78 (Annex II) - List of Noxious Liquid Substances Carried in Bulk
creosote, wood (CAS: 8013-10-3) is found on the following regulatory lists;
Australia Inventory of Chemical Substances (AICS)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix E (Part 2)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix F (Part 3)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Schedule 6
Australia Therapeutic Goods Administration (TGA) Substances that may be used as active ingredients in Listed medicines
Section 16 - OTHER INFORMATION
Denmark Advisory list for selfclassification of dangerous substances
Substance CAS Suggested codes
creosol 93- 51- 6 Xn; R22 R43
REPRODUCTIVE HEALTH GUIDELINES
These exposure guidelines have been derived from a screening level of risk assessment and
CREOSOTE OIL 32
(Chemwatch name: CREOSOTE, WOOD)
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 4139-25
Issue Date: 19-Jul-2003 Version No:2.0
NC317TLP CD 2007/3 Page 17 of 17
Section 16 - OTHER INFORMATION
should not be construed as unequivocally safe limits. ORGS represent an 8-hour time
-weighted average unless specified otherwise.
CR = Cancer Risk/10000; UF = Uncertainty factor:
TLV believed to be adequate to protect reproductive health:
LOD: Limit of detection
Toxic endpoints have also been identified as:
D = Developmental; R = Reproductive; TC = Transplacental carcinogen
Jankovic J., Drake F.: A Screening Method for Occupational Reproductive
American Industrial Hygiene Association Journal 57: 641-649 (1996).
#32orgtc
Ingredient ORG UF Endpoi CR Adeq
nt TLV
benz[a]pyrene 0.000175 mg/m3 NA TC 1 -
These exposure guidelines have been derived from a screening level of risk assessment and
should not be construed as unequivocally safe limits. ORGS represent an 8-hour time
-weighted average unless specified otherwise.
CR = Cancer Risk/10000; UF = Uncertainty factor:
TLV believed to be adequate to protect reproductive health:
LOD: Limit of detection
Toxic endpoints have also been identified as:
D = Developmental; R = Reproductive; TC = Transplacental carcinogen
Jankovic J., Drake F.: A Screening Method for Occupational Reproductive
American Industrial Hygiene Association Journal 57: 641-649 (1996).
Classification of the preparation and its individual components has drawn on official and
authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 19-Jul-2003
Print Date: 17-Dec-2007
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