N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 1 of 13
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
N,N-DIMETHYLFORMAMIDE
SYNONYMS
C3-H7-N-O, H-CO-N-(CH3)2, "dimethyl formamide", dimethylformamide, "formyl dimethylamine"
, formyldimethylamine, formdimethylamide, DMF, DMFA
PROPER SHIPPING NAME
N, N- DIMETHYLFORMAMIDE
PRODUCT USE
Solvent for liquids and gases. In the synthesis of organic compounds; wherever a solvent
with a low rate of evaporation is required. Employed as a booster or co- solvent in
applications such as coatings, adhesives, films and printing inks. A component of many
paint removers. A solvent for polyacrylic fibres.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Quantum Industrial Park
Dandenong South VIC 3175
Australia
Telephone: 1300 782 688
Emergency Tel: 1300 131 001
Fax: 1300 782 699
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 2 of 13
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. DANGEROUS GOODS. According to the Criteria of NOHSC,
and the ADG Code.
POISONS SCHEDULE
S6, NZS3
RISK SAFETY
Flammable. Keep locked up.
Harmful by inhalation and in contact with skin. Keep away from sources of ignition. No smoking.
Irritating to eyes. Keep container in a well ventilated place.
May cause harm to the unborn child. Avoid exposure - obtain special instructions
before use.
Limited evidence of a carcinogenic effect*. To clean the floor and all objects contaminated
by this material, use water.
* (limited evidence). Keep container tightly closed.
This material and its container must be disposed
of in a safe way.
Keep away from food, drink and animal feeding
stuffs.
Take off immediately all contaminated clothing.
In case of contact with eyes, rinse with plenty
of water and contact Doctor or Poisons
Information Centre.
This material and its container must be disposed
of as hazardous waste.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
N, N- dimethylformamide 68-12-2 >98
Section 4 - FIRST AID MEASURES
SWALLOWED
For advice, contact a Poisons Information Centre or a doctor.
路 IF SWALLOWED, REFER FOR MEDICAL ATTENTION, WHERE POSSIBLE, WITHOUT DELAY.
路 For advice, contact a Poisons Information Centre or a doctor.
Where Medical attention is not immediately available or where the patient is more than 15
minutes from a hospital or unless instructed otherwise:
路 Induce vomiting with fingers down the back of the of the throat, ONLY IF CONSCIOUS.
路 Lean patient forward or place on left side (head-down position if possible) to maintain
open airway and prevent aspiration.
NOTE: Wear a protective glove when inducing vomiting by mechanical means.
路 In the mean time, qualified first-aid personnel should treat the patient following
observation and employing supportive measures as indicated by the patient's condition.
路 If the services of a medical officer or medical doctor are readily available, the
N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 3 of 13
Section 4 - FIRST AID MEASURES
patient should be placed in his/her care and a copy of the MSDS should be provided.
Further action will be the responsibility of the medical specialist.
路 If medical attention is not available on the worksite or surroundings send the patient
to a hospital together with a copy of the MSDS.
EYE
If this product comes in contact with the eyes:
路 Immediately hold eyelids apart and flush the eye continuously with running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 Continue flushing until advised to stop by the Poisons Information Centre or a doctor,
or for at least 15 minutes.
路 Transport to hospital or doctor without delay.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
SKIN
If skin contact occurs:
路 Immediately remove all contaminated clothing, including footwear
路 Flush skin and hair with running water (and soap if available).
路 Seek medical attention in event of irritation.
INHALED
路 If fumes or combustion products are inhaled remove from contaminated area.
路 Lay patient down. Keep warm and rested.
路 Prostheses such as false teeth, which may block airway, should be removed, where
possible, prior to initiating first aid procedures.
路 Apply artificial respiration if not breathing, preferably with a demand valve
resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary.
路 Transport to hospital, or doctor, without delay.
NOTES TO PHYSICIAN
Treat symptomatically.
Depending on the degree of exposure, preplacement and periodic medical
examination is desirable, especially evaluating the liver and kidney
functions, and possible skin effects.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
Dry chemical powder.
路 Alcohol stable foam.
Water spray or fog.
Carbon dioxide.
DO NOT use halogenated fire extinguishing agents.
FIRE FIGHTING
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Wear full body protective clothing with breathing apparatus.
路 Prevent, by any means available, spillage from entering drains or water course.
路 If safe, switch off electrical equipment until vapour fire hazard removed.
路 Use water delivered as a fine spray to control fire and cool adjacent area.
路 Avoid spraying water onto liquid pools.
路 DO NOT approach containers suspected to be hot.
路 Cool fire exposed containers with water spray from a protected location.
路 If safe to do so, remove containers from path of fire.
N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 4 of 13
Section 5 - FIRE FIGHTING MEASURES
FIRE/EXPLOSION HAZARD
路 Liquid and vapour are flammable.
路 Moderate fire hazard when exposed to heat or flame.
路 Vapour forms an explosive mixture with air.
路 Moderate explosion hazard when exposed to heat or flame.
路 Vapour may travel a considerable distance to source of ignition.
路 Heating may cause expansion or decomposition leading to violent rupture of containers.
路 On combustion, may emit toxic fumes of carbon monoxide (CO).
Other combustion products include:
carbon dioxide (CO2), nitrogen oxides (NOx) and amines.
HAZCHEM: 2W
Personal Protective Equipment
Breathing apparatus.
Chemical splash suit.
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
Clean up all spills immediately.
Avoid breathing vapours and contact with skin and eyes.
Wear protective clothing, impervious gloves and safety glasses.
Shut off all possible sources of ignition and increase ventilation.
Wipe up and absorb small quantities with vermiculite or other absorbent material.
Place spilled material in clean, dry, sealable, labelled container.
MAJOR SPILLS
Clear area of personnel and move upwind.
Alert Fire Brigade and tell them location and nature of hazard.
路 May be violently or explosively reactive.
路 Wear full body protective clothing with breathing apparatus.
路 Prevent, by any means available, spillage from entering drains or water and water
courses.
Shut off all possible sources of ignition and increase ventilation.
No smoking or naked lights within area.
Stop leak if safe to do so.
Any electric cleaning equipment must be explosion proof.
Contain spill with sand, earth or vermiculite.
Water spray or fog may be used to disperse vapour.
Collect recoverable product into labelled containers for recycling.
Absorb remaining product with sand, earth or vermiculite.
Collect, using a spark-free shovel, and seal in labelled drums for disposal.
If contamination of drains or waterways occurs, advise emergency services.
PROTECTIVE ACTIONS FOR SPILL
N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 5 of 13
Section 6 - ACCIDENTAL RELEASE MEASURES
PROTECTIVE ACTION ZONE
half
evacuation
downwind
direction
distance
down wind distance
wind isolation
distance
direction
half
evacuation downwind
INITIAL direction distance
ISOLATION
ZONE
From IERG (Canada/Australia)
Isolation Distance 25 metres
Downwind Protection Distance 250 metres
IERG Number 19
FOOTNOTES
1 PROTECTIVE ACTION ZONE is defined as the area in which people are at risk of harmful exposure. This zone
assumes that random changes in wind direction confines the vapour plume to an area within 30 degrees on
either side of the predominant wind direction, resulting in a crosswind protective action distance equal
to the downwind protective action distance.
2 PROTECTIVE ACTIONS should be initiated to the extent possible, beginning with those closest to the spill
and working away from the site in the downwind direction. Within the protective action zone a level of
vapour concentration may exist resulting in nearly all unprotected persons becoming incapacitated and
unable to take protective action and/or incurring serious or irreversible health effects.
3 INITIAL ISOLATION ZONE is determined as an area, including upwind of the incident, within which a high
probability of localised wind reversal may expose nearly all persons without appropriate protection to
life-threatening concentrations of the material.
4 SMALL SPILLS involve a leaking package of 200 litres (55 US gallons) or less, such as a drum (jerrican or
box with inner containers). Larger packages leaking less than 200 litres and compressed gas leaking from
a small cylinder are also considered "small spills".
LARGE SPILLS involve many small leaking packages or a leaking package of greater than 200 litres, such as
a cargo tank, portable tank or a "one-tonne" compressed gas cylinder.
5 Guide 129 is taken from the US DOT emergency response guide book.
6 IERG information is derived from CANUTEC - Transport Canada.
EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)
The maximum airborne concentration below which it is believed that nearly all individuals could be exposed
for up to one hour WITHOUT experiencing or developing
life-threatening health effects is:
N,N-dimethylformamide 200 ppm
irreversible or other serious effects or symptoms which could impair an individual's ability to take
protective action is:
N,N-dimethylformamide 100 ppm
other than mild, transient adverse effects without perceiving a clearly defined odour is:
N,N-dimethylformamide 2 ppm
The threshold concentration below which most people will experience no appreciable risk of health effects:
N,N-dimethylformamide 2 ppm
American Industrial Hygiene Association (AIHA)
Ingredients considered according to the following cutoffs
Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0%
R50 >= 0.25% Corrosive (C) >= 5.0%
N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 6 of 13
Section 6 - ACCIDENTAL RELEASE MEASURES
R51 >= 2.5%
else >= 10%
where percentage is percentage of ingredient found in the mixture
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
___________________________________________
X X X X X +
___________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
路 Avoid all personal contact, including inhalation.
路 Wear protective clothing when risk of overexposure occurs.
路 Use in a well-ventilated area.
路 Prevent concentration in hollows and sumps.
路 DO NOT enter confined spaces until atmosphere has been checked.
路 Avoid smoking, naked lights or ignition sources.
路 Avoid generation of static electricity.
路 DO NOT use plastic buckets.
路 Earth all lines and equipment.
路 Use spark-free tools when handling.
路 Avoid contact with incompatible materials.
路 When handling, DO NOT eat, drink or smoke.
路 Keep containers securely sealed when not in use.
路 Avoid physical damage to containers.
路 Always wash hands with soap and water after handling.
路 Work clothes should be laundered separately.
路 Use good occupational work practice.
路 Observe manufacturer's storing and handling recommendations.
路 Atmosphere should be regularly checked against established exposure standards to ensure
safe working conditions.
SUITABLE CONTAINER
路 Check that containers are clearly labelled.
Packaging as recommended by manufacturer.
Store in metal drums or safety cans.
Steel drum.
High purity DMF, required for acrylic fibres, is best stored in aluminium
tanks.
STORAGE INCOMPATIBILITY
路 Avoid oxidising agents, acids, acid chlorides, acid anhydrides.
Reacts violently with aluminium alkyls, 2,5-bis-endo-dichloro-
7-bicyclo[2.2.1]heptane, carbon tetrachloride (above 65 C.),
2,5-dimethylpyrrole and phosphorous trichloride mixture, halogens,
halogenated hydrocarbons and metal mixtures, highly halogenated compounds
like carbon tetrachloride and hexachlorocyclohexane in the presence of iron,
lithium azide, phosphorous trioxide, sodium and compounds.
May polymerise violently with methylene diisocyanate.
N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 7 of 13
Section 7 - HANDLING AND STORAGE
Reacts with borohydride and 2,4,6-trichloro-1,3,5-triazine.
May attack brass, copper and its alloys, plastic, rubber and coatings.
STORAGE REQUIREMENTS
路 Store in original containers in approved flammable liquid storage area.
路 DO NOT store in pits, depressions, basements or areas where vapours may be trapped.
路 No smoking, naked lights, heat or ignition sources.
路 Keep containers securely sealed.
路 Store away from incompatible materials in a cool, dry, well-ventilated area.
路 Protect containers against physical damage and check regularly for leaks.
路 Observe manufacturer's storing and handling recommendations.
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA TWA STEL STEL Peak Peak TWA
ppm mg/m鲁 ppm mg/m鲁 ppm mg/m鲁 F/CC
_________________ __________________ ______ ______ ______ ______ ______ ______ _____
Australia Exposure N, N- 10 30
Standards dimethylformamide
(Dimethylformamide
)
ODOUR SAFETY FACTOR (OSF)
OSF=4.5 ("N,N-DIMETHYL FORMAMIDE")
Exposed individuals are NOT reasonably expected to be warned, by smell, that the Exposure
Standard is being exceeded.
Odour Safety Factor (OSF) is determined to fall into either Class C, D or E.
The Odour Safety Factor (OSF) is defined as:
OSF= Exposure Standard (TWA) ppm/ Odour Threshold Value (OTV) ppm
Classification into classes follows:
Class OSF Description
A 550 Over 90% of exposed
individuals are aware by smell
that the Exposure Standard
(TLV- TWA for example) is
being reached, even when
distracted by working
activities
B 26- 550 As " A" for 50- 90% of persons
being distracted
C 1- 26 As " A" for less than 50% of
persons being distracted
D 0.18- 1 10- 50% of persons aware of
being tested perceive by smell
that the Exposure Standard is
being reached
E <0.18 As " D" for less than 10% of
persons aware of being tested
.
MATERIAL DATA
Odour Threshold Value: 0.047 ppm, 100 ppm (recognition)
NOTE: Detector tubes for dimethylformamide, measuring in excess of 10 ppm,
are commercially available.
DMF is toxic to the liver. Numerous studies have attempted to establish
N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 8 of 13
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
whether DMF causes foetal malformation. The reports that have
undergone examination for reproducibility, accuracy and clarity by the
ACGIH and indicate that DMF does not cause malformations but does produce
increased embryonic deaths when doses approach the lethal level for the
female parent of the species. These doses are greatly in excess of the
dose available by exposure at the TLV.
PERSONAL PROTECTION
EYE
路 Chemical goggles.
路 Full face shield.
DO NOT wear contact lenses.
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
Butyl rubber gloves.
OTHER
Overalls.
路 Impervious protective clothing.
路 Skin cleansing cream.
路 Barrier cream.
路 Eyewash unit.
Ensure there is ready access to a safety shower.
GLOVE SELECTION INDEX
Glove selection is based on a modified presentation of the:
" Forsberg Clothing Performance Index" .
The effect(s) of the following substance(s) are taken into account in the
computer- generated selection: N, N- dimethylformamide
Protective Material CPI *.
__________________________________________
BUTYL A
BUTYL/NEOPRENE A
SARANEX- 23 2- PLY A
VITON/CHLOROBUTYL A
PE/EVAL/PE A
TEFLON B
CPE B
SARANEX- 23 C
NATURAL+NEOPRENE C
PVA C
NEOPRENE C
N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 9 of 13
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
NATURAL RUBBER C
NITRILE+PVC C
PVC C
NITRILE C
__________________________________________
* CPI - Chemwatch Performance Index
A: Best Selection
B: Satisfactory; may degrade after 4 hours continuous immersion
C: Poor to Dangerous Choice for other than short term immersion
NOTE: As a series of factors will influence the actual performance of the glove,
a final selection must be based on detailed observation. -
* Where the glove is to be used on a short term, casual or infrequent basis,
factors such as "feel" or convenience (e.g. disposability), may dictate a choice
of gloves which might otherwise be unsuitable following long-term or frequent use.
A qualified practitioner should be consulted.
RESPIRATOR
Selection of the Class and Type of respirator will depend upon the level of breathing
zone contaminant and the chemical nature of the contaminant. Protection Factors (defined
as the ratio of contaminant outside and inside the mask) may also be important.
Breathing Zone Level Maximum Protection Half- face Respirator Full- Face Respirator
ppm (volume) Factor
1000 10 A- AUS -
1000 50 - A- AUS
5000 50 Airline * -
5000 100 - A- 2
10000 100 - A- 3
100+ Airline**
* - Continuous Flow ** - Continuous-flow or positive pressure demand.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
Local exhaust ventilation may be required for safe working, i.e. to keep exposures below
required standards, otherwise PPE is required.
If inhalation risk of overexposure exists, wear SAA approved organic-vapour
respirator.
Provide adequate ventilation in warehouse or closed storage areas.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Clear, colourless to slightly yellow, mobile liquid with an amine- like (fishy) or
ammonia- like odour. Viscosity : 0.802 mPa sec @ 25C. Completely miscible in water and
readily dissolves many resins and polymers.
PHYSICAL PROPERTIES
Liquid.
Mixes with water.
Molecular Weight: 73.11 Boiling Range (掳C): 153
Melting Range (掳C): - 61 Specific Gravity (water=1): 0.94 @ 25C
Solubility in water (g/L): Miscible pH (as supplied): Not applicable
pH (1% solution): <7 slightly acid Vapour Pressure (kPa): 0.5 @ 25C
N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 10 of 13
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Volatile Component (%vol): 100 Evaporation Rate: 0.17 BuAc=1
Relative Vapour Density (air=1): 2.5 Flash Point (掳C): 58
Lower Explosive Limit (%): 2.2 Upper Explosive Limit (%): 15.2
Autoignition Temp (掳C): 445 Decomposition Temp (掳C): Not available
State: Liquid Viscosity: Not available
log Kow (Sangster 1997): - 1.01
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
Presence of heat source and ignition source.
Presence of incompatible materials.
Product is considered stable under normal handling conditions.
Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
Considered an unlikely route of entry in commercial/industrial environments.
The liquid is discomforting to the gastro-intestinal tract and may be harmful if
swallowed in large quantity.
EYE
The liquid is discomforting to the eyes and is capable of causing a mild, temporary
redness of the conjunctiva (similar to wind-burn), temporary impairment of vision and/ or
other transient eye damage/ ulceration.
The vapour is.
The material may produce severe irritation to the eye causing pronounced inflammation.
Repeated or prolonged exposure to irritants may produce conjunctivitis.
SKIN
The liquid may produce skin discomfort following prolonged contact. Defatting and/or
drying of the skin may lead to dermatitis.
Toxic effects may result from skin absorption.
The material may cause skin irritation after prolonged or repeated exposure and may
produce on contact skin redness, swelling, the production of vesicles, scaling and
thickening of the skin.
INHALED
The vapour is harmful and discomforting to the upper respiratory tract and lungs.
Inhalation hazard is increased at higher temperatures. the material may present a hazard
from repeated exposures over long periods.
Overexposure can lead to injury to liver and kidneys.
Toxic effects are increased by consumption of alcohol.
Symptoms of exposure may be delayed.
CHRONIC HEALTH EFFECTS
Principal routes of exposure are by accidental skin and eye contact and by inhalation of
vapours especially at higher temperatures.
TOXICITY AND IRRITATION
TOXICITY IRRITATION
N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 11 of 13
Section 11 - TOXICOLOGICAL INFORMATION
Oral (rat) LD50: 2800 mg/kg Skin (human): 100%/24h - Mild
Inhalation (human) TCLo: 20 ppm Skin (rabbit): 10 mg/24h (open)
Eye (rabbit):100mg(rinsed)- SEVERE
Dermal (rabbit): 4720 mg/kg Eye (rabbit): 20 mg (open)
The substance is classified by IARC as Group 3:
NOT classifiable as to its carcinogenicity to humans.
Evidence of carcinogenicity may be inadequate or limited in animal testing.
MATERIAL CARCINOGEN REPROTOXIN SENSITISER SKIN
________________________ ____________________ ________________ ________________ ___________
N, N- dimethylformamide IARC:3 ILOEl
CARCINOGEN
IARC: International Agency for Research on Cancer (IARC) Carcinogens:
N,N-dimethylformamide Category: 3
REPROTOXIN
ILOEl: ILO Chemicals in the electronics industry that have toxic effects on
reproduction: N,N-dimethylformamide
Section 12 - ECOLOGICAL INFORMATION
Hazardous Air Pollutant: Yes
log Kow (Sangster 1997): - 1.01
log Pow (Verschueren 1983): 1.47457627
log Kow: -1.01
Koc: 7
Half-life (hr) air: 2
Henry's atm m鲁 /mol: 7.39E-08
Log BCF: -1
Toxicity Fish: LC50(96)2695-3677mg/L
Bioacculmulation: not sig
Degradation Biological: little, slow
processes Abiotic: RxnOH*,hydrol&photol not sig
Section 13 - DISPOSAL CONSIDERATIONS
Recycle wherever possible.
Consult manufacturer for recycling options.
Consult State Land Waste Management Authority for disposal.
DO NOT discharge into sewer or waterways.
Incinerate residue at an approved site.
Recycle containers if possible, or dispose of in an authorised landfill.
Section 14 - TRANSPORTATION INFORMATION
Labels Required: FLAMMABLE LIQUID
HAZCHEM: 2W
UNDG:
N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 12 of 13
Section 14 - TRANSPORTATION INFORMATION
Dangerous Goods 3 Subrisk: None
Class:
UN Number: 2265 Packing Group: III
Shipping Name:N,N-DIMETHYLFORMAMIDE
Air Transport IATA:
ICAO/IATA Class: 3 ICAO/IATA Subrisk: None
UN/ID Number: 2265 Packing Group: III
ERG Code: 3L
Shipping Name: N,N-Dimethylformamide
Maritime Transport IMDG:
IMDG Class: 3 IMDG Subrisk: None
UN Number: 2265 Packing Group: III
EMS Number: F- E, S- D
Shipping Name: N,N-DIMETHYLFORMAMIDE
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: S6, NZS3
REGULATIONS
N,N-dimethylformamide (CAS: 68-12-2) is found on the following regulatory lists;
Australia Exposure Standards
Australia Inventory of Chemical Substances (AICS)
Australia Poisons Schedule
IMO MARPOL 73/78 (Annex II) - List of Noxious Liquid Substances Carried in Bulk
International Agency for Research on Cancer (IARC) Carcinogens
International Council of Chemical Associations (ICCA) - High Production Volume List
OECD Representative List of High Production Volume (HPV) Chemicals
Section 16 - OTHER INFORMATION
REPRODUCTIVE HEALTH GUIDELINES
Established occupational exposure limits frequently do not take into consideration
reproductive end points that are clearly below the thresholds for other toxic effects.
Occupational reproductive guidelines (ORGs) have been suggested as an additional
standard. These have been established after a literature search for reproductive no
-observed-adverse effect-level (NOAEL) and the lowest-observed-adverse-effect-level
(LOAEL). In addition the US EPA's procedures for risk assessment for hazard
identification and dose-response assessment as applied by NIOSH were used in the creation
of such limits. Uncertainty factors (UFs) have also been incorporated.
Ingredient ORG UF Endpoint CR Adeq TLV
N,N-dimethylformamide 1.35 mg/m3 100 D NA -
These exposure guidelines have been derived from a screening level of risk assessment and
should not be construed as unequivocally safe limits. ORGS represent an 8-hour time
-weighted average unless specified otherwise.
CR = Cancer Risk/10000; UF = Uncertainty factor:
TLV believed to be adequate to protect reproductive health:
LOD: Limit of detection
Toxic endpoints have also been identified as:
D = Developmental; R = Reproductive; TC = Transplacental carcinogen
Jankovic J., Drake F.: A Screening Method for Occupational Reproductive
American Industrial Hygiene Association Journal 57: 641-649 (1996).
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
N,N-DIMETHYLFORMAMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2265
NC317TCP CD 2006/4 Page 13 of 13
Section 16 - OTHER INFORMATION
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 16-Aug-2006
Print Date: 4-Jan-2007
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