CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 1 of 15
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
CUMENE HYDROPEROXIDE
SYNONYMS
C9-H12-O2, C6H5C(CH3)2OOH, "isopropylbenzene hydroperoxide", "hydroperoxide, alpha,
alpha-dimethylbenzyl-", "cumenyl hydroperoxide", "alpha-cumyl hydroperoxide", "alpha,
alpha-dimethylbenzyl hydroperoxide", CHP, "cumene hydroperoxide technically pure"
PROPER SHIPPING NAME
ORGANIC PEROXIDE TYPE F, LIQUID
PRODUCT USE
Used in the production of acetone and phenol. As a free radical source, polymerisation
catalyst, i.e. in redox systems for rapid polymerisation. As a peroxide initiator for
vinyl, acrylic monomers and polyester resins. As a substitute for glutathione peroxidase.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Quantum Industrial Park
Dandenong South VIC 3175
Australia
Telephone: 1300 782 688
Emergency Tel: 1300 131 001
Fax: 1300 782 699
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 2 of 15
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. DANGEROUS GOODS. According to the Criteria of NOHSC,
and the ADG Code.
POISONS SCHEDULE
None
RISK SAFETY
Risk of explosion by shock friction fire or Keep locked up.
other sources of ignition.
Forms very sensitive explosive metallic Keep away from combustible material.
compounds.
Contact with combustible material may cause Do not breathe gas/ fumes/ vapour/ spray.
fire.
Flammable. Avoid contact with eyes.
Harmful in contact with skin and if swallowed. Wear suitable protective clothing.
Toxic by inhalation. In case of insufficient ventilation wear
suitable respiratory equipment.
Causes burns. Use only in well ventilated areas.
Risk of serious damage to eyes. Keep container in a well ventilated place.
Harmful: danger of serious damage to health by To clean the floor and all objects contaminated
prolonged exposure through inhalation and if by this material use water and detergent.
swallowed.
Toxic to aquatic organisms may cause long- term Keep container tightly closed.
adverse effects in the aquatic environment.
HARMFUL - May cause lung damage if swallowed. This material and its container must be disposed
of in a safe way.
Cumulative effects may result following Keep away from food drink and animal feeding
exposure*. stuffs.
Possible skin sensitiser*. Take off immediately all contaminated clothing.
* (limited evidence). In case of accident or if you feel unwell
IMMEDIATELY contact Doctor or Poisons
Information Centre (show label if possible).
If swallowed IMMEDIATELY contact Doctor or
Poisons Information Centre (show this container
or label).
Use appropriate container to avoid environment
contamination.
Avoid release to the environment. Refer to
special instructions/ safety data sheets.
This material and its container must be disposed
of as hazardous waste.
In case of accident by inhalation: remove
casualty to fresh air and keep at rest.
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 3 of 15
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
cumene hydroperoxide 80-15-9 88-90
commercial material may contain impurities as
isopropyl benzene - cumene 98-82-8 1-10
alpha, alpha- dimethylbenzyl alcohol 617-94-7 1-10
water 7732-18-5 1-5
acetophenone 98-86-2 0-1
No other ingredient information supplied.
Section 4 - FIRST AID MEASURES
SWALLOWED
DO NOT delay.
Immediately transport to hospital or doctor.
路 For advice, contact a Poisons Information Centre or a doctor at once.
路 Urgent hospital treatment is likely to be needed.
路 If swallowed do NOT induce vomiting.
路 If vomiting occurs, lean patient forward or place on left side (head-down position, if
possible) to maintain open airway and prevent aspiration.
路 Observe the patient carefully.
路 Never give liquid to a person showing signs of being sleepy or with reduced awareness;
i.e. becoming unconscious.
路 Give water to rinse out mouth, then provide liquid slowly and as much as casualty can
comfortably drink.
路 Transport to hospital or doctor without delay.
EYE
DO NOT delay. Immediately transport to hospital or doctor.
If this product comes in contact with the eyes:
路 Immediately hold eyelids apart and flush the eye continuously with running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 Continue flushing until advised to stop by the Poisons Information Centre or a doctor,
or for at least 15 minutes.
路 Transport to hospital or doctor without delay.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
SKIN
If skin or hair contact occurs:
路 Immediately flush body and clothes with large amounts of water, using safety shower if
available.
路 Quickly remove all contaminated clothing, including footwear.
路 Wash skin and hair with running water. Continue flushing with water until advised to
stop by the Poisons Information Centre.
路 Transport to hospital, or doctor.
INHALED
路 If fumes or combustion products are inhaled remove from contaminated area.
路 Lay patient down. Keep warm and rested.
路 Prostheses such as false teeth, which may block airway, should be removed, where
possible, prior to initiating first aid procedures.
路 Apply artificial respiration if not breathing, preferably with a demand valve
resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary.
路 Transport to hospital, or doctor.
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 4 of 15
Section 4 - FIRST AID MEASURES
NOTES TO PHYSICIAN
Treat symptomatically.
Toxic myocarditis may follow ingestion of oxidizing agents such as peroxides.
--------------------------------------------------------------
BASIC TREATMENT
--------------------------------------------------------------
路 Establish a patent airway with suction where necessary.
路 Watch for signs of respiratory insufficiency and assist ventilation as necessary.
路 Administer oxygen by non-rebreather mask at 10 to 15 l/min.
路 Monitor and treat, where necessary, for pulmonary oedema .
路 Monitor and treat, where necessary, for shock.
路 Anticipate seizures .
路 DO NOT use emetics. Where ingestion is suspected rinse mouth and give up to 200 ml
water (5 ml/kg recommended) for dilution where patient is able to swallow, has a strong
gag reflex and does not drool.
路 DO NOT attempt neutralisation as exothermic reaction may occur.
路 Skin burns should be covered with dry, sterile bandages, following decontamination.
--------------------------------------------------------------
ADVANCED TREATMENT
--------------------------------------------------------------
路 Consider orotracheal or nasotracheal intubation for airway control in unconscious
patient or where respiratory arrest has occurred.
路 Positive-pressure ventilation using a bag-valve mask might be of use.
路 Monitor and treat, where necessary, for arrhythmias.
路 Start an IV D5W TKO. If signs of hypovolaemia are present use lactated Ringers
solution. Fluid overload might create complications.
路 Drug therapy should be considered for pulmonary oedema.
路 Hypotension with signs of hypovolaemia requires the cautious administration of fluids.
Fluid overload might create complications.
路 Treat seizures with diazepam.
路 Proparacaine hydrochloride should be used to assist eye irrigation.
BRONSTEIN, A.C. and CURRANCE, P.L.
EMERGENCY CARE FOR HAZARDOUS MATERIALS EXPOSURE: 2nd Ed. 1994.
An in vitro study showed that cumene hydroperoxide penetrates human red
blood cells and is reduced by glutathione in a reaction catalysed by
glutathione peroxidase to cumenol, water and oxidised glutathione.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 Water spray or fog.
路 Foam.
路 Dry chemical powder.
路 BCF (where regulations permit).
路 Carbon dioxide.
FIRE FIGHTING
Alert Fire Brigade and tell them location and nature of hazard.
路 May be violently or explosively reactive.
路 Wear full body protective clothing with breathing apparatus.
路 Prevent, by any means available, spillage from entering drains or water courses.
Fight fire from a safe distance, with adequate cover.
DO NOT approach containers suspected to be hot.
Cool fire exposed containers with water spray from a protected location.
If safe to do so, remove containers from path of fire.
Equipment should be thoroughly decontaminated after use.
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 5 of 15
Section 5 - FIRE FIGHTING MEASURES
FIRE/EXPLOSION HAZARD
Liquid and vapour are flammable.
Dangerous hazard when exposed to heat or flame.
Contact with readily oxidisable organic material may cause ignition /fire.
Reacts violently with many incompatible materials.
Heating may cause expansion or decomposition leading to violent rupture of containers.
Agitation or physical shock may cause violent rupture of containers.
Decomposes on heating and produces toxic fumes of carbon monoxide (CO).
WARNING: Decomposition may occur after prolonged storage.
Decomposition products are combustible.
FIRE INCOMPATIBILITY
路 Amines and polyester accelerators (cobalt salts, for example) if mixed with organic
peroxides / organic peroxide mixtures will cause rapid / spontaneous decomposition
with fire / explosion hazard.
路 Avoid any contamination.
路 Avoid finely divided combustible materials
路 Avoid all external heat.
路 Avoid mixing or reaction with acids, alkalies, reducing agents, metal powders, metal
oxides, transition metals and their compounds.
路 Alkalies decompose peroxides / peroxide mixtures and may generate large volumes of
carbon dioxide and pressurize containers.
路 Avoid contact with copper, brass and zinc (containers or stirrers, for example).
HAZCHEM: 2W
Personal Protective Equipment
Gas tight chemical resistant suit.
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
DO NOT USE RAGS, SAWDUST OR OTHER COMBUSTIBLE MATERIALS TO ABSORB SPILLS.
Contain and absorb spill with sand, earth, inert material or vermiculite.
Collect, using a spark-free shovel, and seal in labelled drums for disposal.
Wash spill area with large quantities of water.
MAJOR SPILLS
DO NOT USE RAGS, SAWDUST OR OTHER COMBUSTIBLE MATERIALS TO ABSORB SPILLS.
No smoking or naked lights within area. Stop leak if safe to do so.
Use extreme caution to avoid a violent reaction.
Absorb or cover spill with sand, earth, inert material or vermiculite.
Collect, using a spark-free shovel, and seal in labelled drums for disposal.
Wash area down with large quantity of water and prevent runoff into drains.
After clean up operations, decontaminate and launder all protective clothing and
equipment before storing and re-using.
EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)
The maximum airborne concentration below which it is believed that nearly all individuals could be exposed
for up to one hour WITHOUT experiencing or developing
life-threatening health effects is:
cumyl hydroperoxide 150 mg/m鲁
irreversible or other serious effects or symptoms which could impair an individual's ability to take
protective action is:
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 6 of 15
Section 6 - ACCIDENTAL RELEASE MEASURES
cumyl hydroperoxide 150 mg/m鲁
other than mild, transient adverse effects without perceiving a clearly defined odour is:
cumyl hydroperoxide 30 mg/m鲁
The threshold concentration below which most people will experience no appreciable risk of health effects:
cumyl hydroperoxide 10 mg/m鲁
American Industrial Hygiene Association (AIHA)
Ingredients considered according to the following cutoffs
Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0%
R50 >= 0.25% Corrosive (C) >= 5.0%
R51 >= 2.5%
else >= 10%
where percentage is percentage of ingredient found in the mixture
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
Avoid breathing vapours and contact with skin and eyes.
Use good occupational work practice.
Avoid physical damage to containers.
Avoid smoking, naked lights or ignition sources.
Avoid shock and friction.
Wear protective clothing and gloves when handling containers.
Handle and open container with care.
When handling, DO NOT eat, drink or smoke.
Use in a well-ventilated area.
Decant in a well-ventilated area or under an exhaust hood.
Always wash hands with soap and water after handling. Work clothes should be laundered
separately.
SUITABLE CONTAINER
Type E and F Liquid Organic Peroxides, UN 3107, and UN 3109, UN 3117 and UN 3119 are to
be packed to the requirements of Packing method OP8 of the UN Dangerous Goods Code, with
maximum mass of 200 kg. or 225 l. volume, in a plastic drum/ container or plastic inner
receptacle in metal outer drum.
May be transported in bulk containers.
STORAGE INCOMPATIBILITY
Avoid any contamination of this material as it is very reactive and any contamination is
potentially hazardous.
Hazardous, even explosive polymerisation may result from mixing with incompatible
materials.
May be unstable unless stored under controlled conditions.
Segregate from mineral acids, organic materials, particularly finely
divided organic material, paint driers, polyester or FRP resin
accelerators, amines, resin promoters, zinc, cast iron, copper and brass.
Most alkylhydroperoxides are liquid and their explosivity increases with decreasing chain
length (possibly due to the presence of trace amounts of dialkyl peroxides). Transition
metal complexes may decompose explosively.
BRETHERICK L.: Handbook of Reactive Chemical Hazards.
STORAGE REQUIREMENTS
Store below 38 deg. C. Outside or detached storage is preferred.
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 7 of 15
Section 7 - HANDLING AND STORAGE
Observe manufacturer's storing and handling recommendations.
Store in original containers.
Store away from incompatible materials.
Store away from sources of heat or ignition / naked lights.
Store in a cool area and away from sunlight.
Store in a well-ventilated area.
DO NOT store on wooden floors.
Protect containers against physical damage.
_____________________________________________________
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
X X X X X 0
_____________________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA ppm TWA mg/m鲁 STEL ppm STEL mg/m鲁
_________ _________ _____ _____ _____ _____
Australia isopropyl benzene 25 125 75 375
Exposure - cumene (Cumene)
Standards
The following materials had no OELs on our records
鈥? cumyl hydroperoxide: CAS:80- 15- 9
鈥? alpha, alpha- dimethylbenzyl alcohol: CAS:617- 94- 7
鈥? water: CAS:7732- 18- 5
鈥? acetophenone: CAS:98- 86- 2
EMERGENCY EXPOSURE LIMITS
Material Revised IDLH Value (mg/m3) Revised IDLH Value (ppm)
isopropyl benzene - cumene 900 [LEL]
NOTES
Values marked LEL indicate that the IDLH was based on 10% of the lower explosive limit
for safety considerations even though the relevant toxicological data indicated that
irreversible health effects or impairment of escape existed only at higher
concentrations.
MATERIAL DATA
CEL TWA: 1 ppm, 6 mg/m3 (SKIN) (compare WEEL TWA)
Exposure limits with "skin" notation indicate that vapour and liquid may be absorbed
through intact skin. Absorption by skin may readily exceed vapour inhalation exposure.
Symptoms for skin absorption are the same as for inhalation. Contact with eyes and mucous
membranes may also contribute to overall exposure and may also invalidate the exposure
standard.
Saturated vapour concentration: 2632 ppm at 20 C.
Cumene hydroperoxide is severely irritating to the eyes and skin and is
moderately toxic by ingestion, inhalation and dermal absorption. A 3-month
inhalation study in rats, established a no-effect level of 31 mg/m3
(5 ppm). Animals exposed to 16 ppm for 12 days experienced irritation. An
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 8 of 15
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
environmental exposure level (WEEL) recommended by the AIHA is thought to
be protective against irritation and systemic effects in workers. The skin
notation was included to reflect dermal absorption data.
INGREDIENT DATA
ALPHA,ALPHA-DIMETHYLBENZYL ALCOHOL:
WATER:
No exposure limits set by NOHSC or ACGIH.
ISOPROPYL BENZENE - CUMENE:
Odour Threshold Value: 0.008-0.132 ppm (detection), 0.047 ppm (recognition)
Exposure at or below the TLV-TWA is thought to prevent induction of
narcosis.
ALPHA,ALPHA-DIMETHYLBENZYL ALCOHOL:
CEL TWA: 2 mg/m3 (OEL Russian : 10 mg/m3 skin)
ACETOPHENONE:
Odour Threshold Value: 0.17 ppm
Acetophenone produces narcosis and anaesthesia when swallowed or injected
intravenously or subcutaneously. Contact with the skin produces irritation
and, if confined, may burn. Eye contact may produce marked irritation and
transient corneal injury depending on the extent and duration of contact.
Acute inhalation studies indicate that a saturated atmosphere (nominally
400 ppm) produced no fatalities in rats exposed for 8 hours. Whether the
substance is irritating at or around the reported odour threshold is
inconclusive. Subchronic oral studies indicate no effect on growth or
haematoloy at doses of up to 10000 ppm in the diet. The TLV-TWA is thought
to be protective against the potential irritant or odour effects of
acetophenone.
PERSONAL PROTECTION
EYE
路 Chemical goggles.
路 Full face shield may be required for supplementary but never for primary protection of
eyes
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
路 Barrier cream. and Neoprene gloves or Nitrile gloves or Polyethylene gloves.
Protective footwear.
PVC safety gumboots.
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 9 of 15
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
When handling corrosive liquids, wear trousers or overalls outside of boots, to avoid
spills entering boots.
OTHER
Equipment should be kept clean and in working-order.
PVC apron. or Rubber apron.
路 Ensure that there is ready access to eye wash unit.
Ensure there is ready access to a safety shower.
GLOVE SELECTION INDEX
Glove selection is based on a modified presentation of the:
" Forsberg Clothing Performance Index" .
The effect(s) of the following substance(s) are taken into account in the
computer- generated selection: cumyl hydroperoxide
Protective Material CPI *.
__________________________________________
TEFLON A
__________________________________________
* CPI - Chemwatch Performance Index
A: Best Selection
B: Satisfactory; may degrade after 4 hours continuous immersion
C: Poor to Dangerous Choice for other than short term immersion
NOTE: As a series of factors will influence the actual performance of the glove,
a final selection must be based on detailed observation. -
* Where the glove is to be used on a short term, casual or infrequent basis,
factors such as "feel" or convenience (e.g. disposability), may dictate a choice
of gloves which might otherwise be unsuitable following long-term or frequent use.
A qualified practitioner should be consulted.
RESPIRATOR
Selection of the Class and Type of respirator will depend upon the level of breathing
zone contaminant and the chemical nature of the contaminant. Protection Factors (defined
as the ratio of contaminant outside and inside the mask) may also be important.
Breathing Zone Level Maximum Protection Half- face Respirator Full- Face Respirator
ppm (volume) Factor
1000 10 A- AUS P -
1000 50 - A- AUS P
5000 50 Airline * -
5000 100 - A- 2 P
10000 100 - A- 3 P
100+ Airline**
* - Continuous Flow ** - Continuous-flow or positive pressure demand.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
Use in a well-ventilated area.
Local exhaust ventilation usually required. If risk of overexposure exists, wear approved
respirator. Correct fit is essential to obtain adequate protection. Supplied-air type
respirator may be required in special circumstances. Correct fit is essential to ensure
adequate protection.
An approved self contained breathing apparatus (SCBA) may be required in some situations.
Provide adequate ventilation in warehouse or closed storage area. Air contaminants
generated in the workplace possess varying "escape" velocities which, in turn, determine
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 10 of 15
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
the "capture velocities" of fresh circulating air required to effectively remove the
contaminant.
Type of Contaminant: Air Speed:
solvent, vapours, degreasing etc., evaporating 0.25- 0.5 m/s (50- 100 f/min.)
from tank (in still air).
aerosols, fumes from pouring operations, 0.5- 1 m/s (100- 200 f/min.)
intermittent container filling, low speed
conveyer transfers, welding, spray drift,
plating acid fumes, pickling (released at low
velocity into zone of active generation)
direct spray, spray painting in shallow booths, 1- 2.5 m/s (200- 500 f/min.)
drum filling, conveyer loading, crusher dusts,
gas discharge (active generation into zone of
rapid air motion)
grinding, abrasive blasting, tumbling, high 2.5- 10 m/s (500- 2000 f/min.)
speed wheel generated dusts (released at high
initial velocity into zone of very high rapid
air motion).
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only.
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood- local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
source. The air velocity at the extraction fan, for example, should be a minimum of 1-2
m/s (200-400 f/min) for extraction of solvents generated in a tank 2 meters distant from
the extraction point. Other mechanical considerations, producing performance deficits
within the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or used.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Colourless to pale yellow liquid, with a sharp irritating odour. Slightly soluble in water
(1% at 25 C). Soluble in alcohol, acetone, esters, hydrocarbons, chlorinated hydrocarbons.
PHYSICAL PROPERTIES
Liquid.
Does not mix with water.
Sinks in water.
Corrosive.
Toxic or noxious vapours/gas.
Molecular Weight: Not applicable. Boiling Range (掳C): Explodes
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 11 of 15
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Melting Range (掳C): - 9 Specific Gravity (water=1): 1.03 at 25 C
Solubility in water (g/L): Partly miscible pH (as supplied): 4
pH (1% solution): Not available. Vapour Pressure (kPa): 0.08 at 25 C
Volatile Component (%vol): Not available. Evaporation Rate: Very slow
Relative Vapour Density (air=1): Approx. 5.0 Flash Point (掳C): 80.0
Lower Explosive Limit (%): 0.9 Upper Explosive Limit (%): 6.5
Autoignition Temp (掳C): Not available. Decomposition Temp (掳C): Not available
State: Liquid
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
May be unstable unless stored under controlled conditions.
Presence of heat source and direct sunlight.
Presence of elevated temperatures. 路 Presence of shock and friction.
Hazardous, even explosive polymerisation may result from mixing with incompatible materials.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
Considered an unlikely route of entry in commercial/industrial environments.
The liquid is highly corrosive and toxic if swallowed.
Ingestion may result in nausea, pain, vomiting. Vomit entering the lungs by aspiration
may cause potentially lethal chemical pneumonitis.
Ingestion of organic peroxides may produce nausea, vomiting, abnormal pain, stupor,
bluish discoloration of skin and mucous membranes. Inflammation of the heart muscle may
also occur.
EYE
The liquid is highly corrosive to the eyes and is capable of causing severe damage with
loss of sight.
The material may produce moderate eye irritation leading to inflammation. Repeated or
prolonged exposure to irritants may produce conjunctivitis.
Eye contact with organic peroxides can cause clouding, redness, swelling and burns of the
eye on prolonged contact.
SKIN
Skin contact will result in rapid drying, bleaching, leading to chemical burns on
prolonged contact.
The liquid is corrosive to the skin and may even cause blisters or burns if contact is
prolonged, it is absorbed by the skin and may rarely cause skin sensitisation.
Bare unprotected skin should not be exposed to this material.
Irritation may not occur immediately but may be delayed 24-48 hours.
The material may cause skin irritation after prolonged or repeated exposure and may
produce on contact skin redness, swelling, the production of vesicles, scaling and
thickening of the skin.
Sensitisation may result in allergic dermatitis responses including rash, itching, hives
or swelling of extremities.
Sensitisation reactions may appear suddenly after repeated
symptom free exposures.
All organic peroxides are irritating to the skin and if allowed to remain on the skin,
may produce inflammation; some are allergenic.
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
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Section 11 - TOXICOLOGICAL INFORMATION
INHALED
Not normally a hazard due to non-volatile nature of product.
The vapour/mist is. highly discomforting if inhaled.
Inhalation hazard is increased at higher temperatures.
Reactions may not occur on exposure but response may be delayed with symptoms only
appearing many hours later.
The inhalation of organic peroxide dusts or vapours can produce throat and lung
irritation and cause an asthma-like effect. Over-exposure can cause tears, salivation,
lethargy, slow breathing, breathing difficulties, headache, weakness, tremor, stupor and
swelling of the lung.
Inhalation of quantities of liquid mist may be extremely hazardous, even lethal due to
spasm, extreme irritation of larynx and bronchi, chemical pneumonitis and pulmonary
oedema.
CHRONIC HEALTH EFFECTS
Principal routes of exposure are usually by skin contact with the liquid and inhalation
of vapour.
Persistent exposure over a long period of time to peroxides produces allergic skin
reactions (redness and scaling of the skin) and asthmatic wheezing.
TOXICITY AND IRRITATION
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (rat) LD50: 382 mg/kg Skin (rabbit): 500 mg - Mild
Inhalation (rat) LC50: 220 ppm/4h Eye (rabbit): 1 mg
Dermal (rat) LD50: 500 mg/kg
Bacterial cell mutagen
Equivocal tumorigen by RTECS criteria
ISOPROPYL BENZENE - CUMENE:
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (rat) LD50: 1400 mg/kg Skin (rabbit): 10 mg/24h Mild
Inhalation (human) TCLo: 200 ppm Skin (rabbit):100 mg/24h Moderate
Inhalation (rat) LCLo: 8000 ppm/4h Eye (rabbit): 86 mg Mild
Dermal (rabbit) LD50: 12300 mg/kg Eye (rabbit): 500 mg/24h Mild
Dermal (rabbit) LD50: 2000 mg/kg
ALPHA,ALPHA-DIMETHYLBENZYL ALCOHOL:
TOXICITY IRRITATION
Oral (rat) LD50: 1300 mg/kg Skin (rabbit): 500 mg/24h- SEVERE
Dermal (rabbit) LD50: 4300 mg/kg
WATER:
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
No significant acute toxicological data identified in literature search.
ACETOPHENONE:
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (rat) LD50: 815 mg/kg Skin (rabbit): 10 mg/24h Open
Eye (rabbit): 0.771 mg - SEVERE
Dermal (rabbit): 15900 mg/kg Skin (rabbit): 515 mg open- Mild
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 13 of 15
Section 12 - ECOLOGICAL INFORMATION
Half- life Soil - High (hours): 672
Half- life Soil - Low (hours): 168
Half- life Air - High (hours): 130
Half- life Air - Low (hours): 13
Half- life Surface water - High (hours): 672
Half- life Surface water - Low (hours): 168
Half- life Ground water - High (hours): 1344
Half- life Ground water - Low (hours): 336
Aqueous biodegradation - Aerobic - High (hours): 672
Aqueous biodegradation - Aerobic - Low (hours): 168
Aqueous biodegradation - Anaerobic - High (hours): 2688
Aqueous biodegradation - Anaerobic - Low (hours): 672
Photolysis maximum light absorption - High (nano- m): 264
Photolysis maximum light absorption - Low (nano- m): 242
Photooxidation half- life air - High (hours): 130
Photooxidation half- life air - Low (hours): 13
Effects on algae and plankton: non tox algae 1-2mg/L
Refer to data for ingredients, which follows:
ISOPROPYL BENZENE - CUMENE:
log Kow (Sangster 1997): 3.66
log Pow (Verschueren 1983): 3.66
Do NOT allow product to come in contact with surface waters or to intertidal areas below
the mean high water mark. Do not contaminate water when cleaning equipment or disposing
of equipment wash-waters.
Wastes resulting from use of the product must be disposed of on site or at approved waste
sites.
DO NOT discharge into sewer or waterways.
Drinking Water Standards:
hydrocarbon total: 10 ug/l (UK max.).
Half-life (hr) air: 2.4-24
Half-life (hr) H2O surface water: 5.79
Henry's Pa m鲁 /mol: 942-1521
Log BCF: 1.55-2.27
Bioacculmulation: not sig
Degradation Biological: sig,fast
processes Abiotic: RxnOH*
ACETOPHENONE:
Hazardous Air Pollutant: Yes
Fish LC50 (96hr.) (mg/l): 155- 200
Water solubility (g/l): 6130
log Kow (Prager 1995): 1.58
log Pow (Verschueren 1983): 1.58
log Kow : 1.58
Half-life (hr) air: 528
Half-life (hr) H2O surface water: 91.2-192
Half-life (hr) H2O ground: 768
Henry's atm m鲁 /mol: 1.07E-05
BOD 5 if unstated: 0.518-0.5,32%
ThOD: 2.532
BCF: 5-9
Toxicity Fish: LC50(96)155mg/L
Bioacculmulation: not sig
Degradation Biological: sig
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 14 of 15
Section 12 - ECOLOGICAL INFORMATION
processes Abiotic: nohydrol,RxnOH*,photol
Section 13 - DISPOSAL CONSIDERATIONS
路 Special hazard may exist - specialist advice may be required.
路 Consult State Land Waste Management Authority for disposal.
路 Use 5% aqueous sodium hydroxide or soda ash to neutralise, followed by water.
路 Bury or incinerate residue at an approved site.
路 Decontaminate empty containers with 5% aqueous sodium hydroxide or soda ash, followed
by water.
路 Observe all label safeguards until containers are cleaned and destroyed.
路 Puncture containers to prevent re-use and bury at an authorised landfill.
Section 14 - TRANSPORTATION INFORMATION
Labels Required: ORGANIC PEROXIDE,CORROSIVE
HAZCHEM: 2W
UNDG:
Dangerous Goods Class: 5.2 Subrisk: 8
UN Number: 3109 Packing Group: II
Shipping Name:ORGANIC PEROXIDE TYPE F, LIQUID
Maritime Transport IMDG:
NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS:IATA
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: None
REGULATIONS
cumyl hydroperoxide (CAS: 80-15-9) is found on the following regulatory lists;
Australia Dangerous Goods Code Draft 7th Edition - Goods too Dangerous to be Transported
Australia Dangerous Goods Code Draft 7th Edition - Organic Peroxides
Australia Inventory of Chemical Substances (AICS)
International Council of Chemical Associations (ICCA) - High Production Volume List
OECD Representative List of High Production Volume (HPV) Chemicals
Section 16 - OTHER INFORMATION
Classification of the preparation and its individual components has drawn on official and
authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
CUMENE HYDROPEROXIDE
Chemwatch Material Safety Data Sheet (REVIEW)
For Workplace - Small Volume Use Only. CHEMWATCH 2116
Issue Date: 12-May-2005 Version No:2.0
NC317TLP CD 2007/3 Page 15 of 15
Section 16 - OTHER INFORMATION
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 12-May-2005
Print Date: 17-Dec-2007
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