180090 1.00 EC Current 28.09.2000
1. PRODUCT AND COMPANY IDENTIFICATION
Johnson Matthey PLC
Precious Metals Division, Chemicals
+(44) 1763 253000
+(44) 1763 253155
100% Ammonium Tetrachloroplatinate(II) (NH ) PtCl .
JM Version Number
Date of First Issue
2. COMPOSITION/INFORMATION ON THE COMPONENTS
Product Formal Name
Product Chemical Family
3. HAZARD IDENTIFICATION
Ammonium tetrachloroplatinate(II) is a severe irritant to the eyes and lungs, is
a mild skin irritant and is toxic if swallowed. It is highly allergenic and will
cause Type 1 sensitisation in susceptible individuals. Sensitised persons, on
re-exposure to platinum salts, will show the clinical features of a Type 1
allergy - asthma and/or rhinitis and/or conjunctivitis and/or urticaria. A contact
dermatitis can also occur. 聽
4. FIRST AID MEASURES
First Aid Inhalation of the dust will result in coughing and sneezing and severe irritation
of the respiratory tract, and is the main cause of sensitisation. The symptoms
of the allergic reaction to platinum salts may include any of the following;-
itchy red eyes, watering of the eyes, sneezing, runny nose, chest tightness,
wheezing, breathlessness, cough, eczematous or urticarial (nettle rash type)
skin lesions. Exposure to platinum salts in exceedingly small amounts, even
below the level of physico-chemical detection, will produce symptoms in
sensitised persons. Continued exposure will give symptoms of increasing
severity and can eventually lead to chronic asthma. There is a risk of
anaphylactic shock occuring in sensitised persons re-encountering platinum
salts. Therefore, if sensitisation has developed, further exposure to platinum
compounds must not be permitted. "Platinum asthma" is a prescribed
occupational disease in the UK. Ingestion will lead to severe abdominal pain,
with possible chemical burns to the mouth and throat. Contact with the skin
will be irritating. Strong solutions are corrosive, with the possibility of burns in
severe cases. Contact with the eyes will be painful at all levels of exposure. 聽 聽
remove from exposure and allow to rest in fresh air. Rinse nose and mouth
First Aid - Inhalation
with clean water. If breathing is difficult, give oxygen if available. Get
immediate medical attention. 聽
First Aid - Ingestion rinse mouth with water and give water or milk to drink. Do not induce
vomiting. Get immediate medical attention.
irrigate with water or isotonic saline solution for 15 minutes. Get medical
First Aid - Eyes
First Aid - Skin Remove contaminated clothing and wash skin with copious amounts of soap
and water.If irritation persists or tissue is damaged, get medical attention. 聽 聽
Acute allergic reactions are managed symptomatically as indicated by the
clinical condition. There is no known antidote.
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5. FIRE FIGHTING MEASURES
Although the material is not flammable, toxic fumes will be produced if
involved in a fire. The residue, ash or char left after a fire may have catalytic
properties and may promote the re-ignition of flammable materials and
vapours. Wear self-contained breathing apparatus and personal protective
equipment. Use any extinguisher suitable for the surrounding fire. 聽 聽
6. ACCIDENTAL RELEASE MEASURES
Evacuate non-protected personnel. Wear protective clothing, impervious
gloves, eye protection and filter-type respiratory protection when dealing with
spillages. Solid spills should be carefully collected into a sealable, plastic
lined drum. Solutions should be absorbed in sand or other inert absorbant
and carefully transferred to a plastic lined drum. The site of the spillage may
be treated with an aqueous solution of a reducing agent, to convert any
remaining platinum compounds to the metal. Store accumulated rags, wipes,
mops, sand, vermiculite etc. in suitably labelled containers for return to the
refinery for precious metal recovery. Afterwards, wash the site of the spillage
with copious amounts of water. If the spill has resulted in the dispersion of
dust through the air, the area must be decontaminated by thorough washing
with water. 聽 聽 聽
7. HANDLING AND STORAGE
Good industrial hygiene practices should be observed. Avoid direct contact.
Do not eat, drink, smoke or apply cosmetics whilst handling. Exposure to air-
borne particulates must be kept within permissible limits. Use only under
conditions of good local ventilation. 聽 聽 聽 聽 聽 聽
Keep in a secure store, in a sealed, plastic container, away from incompatible
materials such as reducing agents. 聽 聽
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
UK MEL for halogeno-platinum compounds - 0.002 mg/m鈥?
USA ACGIH TLV-TWA for soluble platinum salts - 0.002 mg/m鈥?
German MAK for platinum compounds, measured as total dust - 0.002 mg/
Danish ELV for soluble platinum compounds - 0.002 mg/m鈥?
All values calculated as Pt. High risk of sensitization.
Local exhaust extraction should be used. Vapour and fumes from all
operations should be vented to external atmosphere via a collection or
scrubbing system. Personal filter type respiratory protection, impervious
gloves and industrial safety glasses should be worn. Work clothes should be
changed as often as necessary and at least after every working shift. Wash
hands after using this material.
Users of large amounts of the solid or its solutions should consider the
application of engineering control measures, such as total enclosure and
remote operation where possible. Workplace air and the exhaust from the
ventilation system should be monitored for airborne platinum to ensure that
exposure limit are not exceded. This monitoring should include personal
breathing zone sampling. Pre-exposure and periodic medical examinations of
persons exposed to platinum salts are recommended. Further details are
given in the HSE's Guidance Note MS22,"The Medical Monitoring of Workers
Exposed to Platinum Salts" (ISBN 0 11 883575 0). For non UK residents,
information is available from the JM Group Occupational Physician. 聽 聽 聽 聽 聽 聽 聽
9. PHYSICAL AND CHEMICAL PROPERTIES
Dark, ruby-red, rhombic crystals.
the aqueous solution is slightly acidic.
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180090 1.00 EC Current 28.09.2000
9. PHYSICAL AND CHEMICAL PROPERTIES (continued)
decomposes on heating at 140 to 150掳C.
Water - Soluble in water. Insoluble in ethanol.
Solubility in Water
Fat - no data. 聽 聽
10. STABILITY AND REACTIVITY
On standing in air, the solid will absorb moisture and may coalesce into a
hard lump. The acidic, aqueous solution will hydrolyse when subjected to
heat and light. Old solutions will contain chloro-hydroxy platinum species.
The solution may be stabilised by the addition of hydrochloric acid. The solid
decomposes on heating, giving off toxic fumes. 聽
11. TOXICOLOGICAL INFORMATION
Toxicological data for the three tetrachloroplatinates is given below.
(1) Potassium Tetrachloroplatinate
LDLo (oral-child) 400 mg/kg, LD50 (ipr-mouse) 45 mg/kg and LD50 (oral-rat)
in the range 50 to 200 mg/kg.
The ingestion of 600 mg of Potassium Tetrachloroplatinate is reported as
causing renal failure, acidosis, fever, muscular cramps and gastroenteritis.
All symptoms resolved over 6 days without need of dialysis.
(2) Ammonium Tetrachloroplatinate
LD50 (ipr-mouse) 60 mg/kg and LD50 (oral-rat) 170 mg/kg.
(3) There is no specific toxicological data available for Sodium
Tetrachloroplatinate, but the LD50 (oral-rat) for the solid is likely to be in the
range 50 to 200 mg/kg i.e. Toxic.
However, the solution, (normally 10%) is classified as Harmful.
Persons with a history of allergic diseases, such as asthma or hay-fever,
should not work with platinum salts. A history of cardiac or pulmonary
diseases may also preclude work with platinum salts - medical opinion should
be sought. Any workers experiencing untoward effects or symptoms should
be removed from exposure and medically examined for platinum sensitivity.
Sensitisation is indicated by positive skin-prick test to low concentration
solutions of platinum salts.
12. ECOLOGICAL INFORMATION
The reproduction of daphnids is impaired (16%) by 0.014 ppm Pt in 3 weeks.
Hydrogen hexachloroplatinate is reported to be lethal to certain freshwater
species. The complex may persist for some time in the environment. 聽 聽
Return accumulated waste material to the refinery for metal recovery, or
dispose of in accordance with local and national regulations. 聽
14. TRANSPORT INFORMATION
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180090 1.00 EC Current 28.09.2000
14. TRANSPORT INFORMATION (continued)
U.N. No. 3288, Class 6.1, Packing Group III
ADR 2601 68(c)
Proper Shipping Name - Toxic solid, inorganic, n.o.s. "Ammonium
tetrachloroplatinate" 聽 聽 聽 聽
15. REGULATORY INFORMATION
R phrases R25 Toxic if swallowed.
R41 Risk of serious damage to eyes.
R42/43 May cause sensitisation by inhalation and skin contact.
S22 Do not breathe dust.
S24 Avoid contact with skin.
S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
T - Toxic
EC Annex I Classification
16. OTHER INFORMATION
28 September 2000
MSDS first issued
MSDS data revised
This information relates only to the specific material designated and may not be valid for such material used in combination
with any other materials or in any process. Such information is given in good faith, being based on the latest information
available to Johnson Matthey PLC and is to the best of Johnson Matthey PLC's knowledge and belief, accurate and reliable at
the time of preparation. However, no representation, warranty or guarantee is made as to the accuracy, liability or
completness and Johnson Matthey PLC assumes no responsibility therefore, and disclaims any liability for any loss, damage
or injury howsoever arising (including in respect of any claim brought by any third party) incurred using this information. The
product is supplied on thecondition that the user accepts responsibility to satisfy himself as to the suitability and completness
of such information for his own particular use. Freedom from patent or any other proprietary rights of any third party must not
be assumed. 聽
Registry of Toxic Effects of Chemical Substances. Published by the National Institute of Occupational Safety and Health. USA.
Oil and Hazardous Materials Technical Assistance Data System. Published by The Office of Water and Waste Management.
Environmental Protection Agency USA.
Chemical Hazard Response Information System. Published by US Coast Guard.
NIOSHTIC Occupational Safety and Health database. Published by the National Institute of Occupational Safety and Health.
HSELINE Health and Safety Executive Library and Information Service. Published by the Health and Safety Executive. UK.
CISDOC International Occupational Safety and Health Database. Published by the International Labour Organisation. Geneva.
RISKLINE. Published by the National Chemical Inspectorate. Sweden.
TOXLINE. Published by the Chemical Abstracts Service. USA.
Developmental and Reproductive Toxicology. The National Library of Medicine. USA.
Toxicity, Bibliography. The National Library of Medicine. USA.
Environmental Mutagen Information. Oak Ridge National Laboratory. USA.
Environmental Teratology Information. Oak Ridge National Laboratory. USA
BIOSIS. Published by Biological Abstracts Inc. USA.
Epidemiology Information. The Food and Drug Administration. USA
International Pharmaceutical Abstracts. The American Society of Hospital Pharmacists. USA.
Hazardous Materials Technical Center Abstracts. Department of the Army, Hazardous Materials Technical Center. USA.
Toxicology Document and Data Depository. National Technical Information Service. USA.
Federal Research in Progress. National Technical Information Service. USA.
Toxicology Research Projects. National Institutes of Health. USA
Toxic Substances Control Act Test Submissions. The Environmental Protection Agency. USA.
Patty's Industrial Hygiene and Toxicology 3rd edition.
Handbook on the Toxicology of Metals. Friberg, Nordberg and Vouk 2nd edition.
Bretherick's Handbook of Reactive Chemical Hazards. 5th edition.
Grant's Toxicology of the Eye. 3rd edition.
Merck Index 10th edition.
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180090 1.00 EC Current 28.09.2000
16. OTHER INFORMATION (continued)
Handbook on Toxicology of Inorganic Compounds. Seiler, Sigel and Sigel.
Catalog of Teratogenic Agents. Shepard. 4th edition
Reproductive Hazards of Industrial Chemicals. Barlow and Sullivan.
Royal Society of Chemistry, Chemical Safety Data Sheets.
National Sales Offices
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840070, Fax:- 721 849674
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99, Fax:- 1 48 63 27 02
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Johnson Matthey A.B., Victor Hasselblads gata 8, S-421 31 V盲stra Fr枚lunda, Sverige, Tel:- 031 891390, Fax:- 31 477795
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Johnson Matthey GmbH, Otto-Volger-Stra脽e 9B, D-65843 Sulzbach/Ts, Deutschland, Tel:- (0 61 96)70 38-21, Fax:- (0 61 96)
70 38 12
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