SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/19/2005
Date Updated: 03/07/2004
Version 1.2
Section 1 - Product and Company Information
Product Name LEAD(II) SULFATE, 98%
Product Number 307734
Brand ALDRICH
Company Sigma-Aldrich
Street Address 3050 Spruce Street
City, State, Zip, Country SAINT LOUIS MO 63103 US
Technical Phone: 314 771 5765
Emergency Phone: 414 273 3850 Ext. 5996
Fax: 800 325 5052
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
LEAD(II) SULFATE 7446-14-2 No
Formula PbSO4
Synonyms Anglislite * Bleisulfat (German) * C.I. 77630 *
C.I. Pigment White 3 * Fast White * Freemans
White Lead * Lead Bottoms * Milk White * Mulhouse
White * Pigment White 3 * Sulfate de plomb
(French) * Sulfuric acid, lead(2+) salt (1:1)
RTECS Number: OG4375000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Harmful.
Irritating to eyes, respiratory system and skin. Limited evidence
of a carcinogenic effect. Harmful by inhalation, in contact with
skin and if swallowed.
Reproductive hazard. Target organ(s): Nerves. Blood. Kidneys.
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
EYE EXPOSURE
Assure adequate flushing of the eyes by separating the eyelids
with fingers.
Section 5 - Fire Fighting Measures
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Dry chemical powder.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
EXPOSURE HAZARD(S)
Material: Irritant. Harmful solid.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe dust. Do not get in eyes, on skin,
on clothing. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep tightly closed. Store in a cool dry place.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
PERSONAL PROTECTIVE EQUIPMENT
Other: Wear appropriate government approved respirator,
chemical-resistant gloves, safety goggles, other protective
clothing. Faceshield (8-inch minimum).
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse. Discard contaminated shoes.
EXPOSURE LIMITS, RTECS
Country Source Type Value
USA ACGIH TWA 0.05 MG(PB)/M3
Remarks: animal carcinogen
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New Zealand OEL
Remarks: check ACGIH TLV
USA NIOSH TWA <0.1 MG(PB)/M3
Section 9 - Physical/Chemical Properties
Appearance Color: Very faintly beige
Form: Powder
Property Value At Temperature or Pressure
Molecular Weight 303.25 AMU
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Freezing Point N/A
Vapor Pressure N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density 6.2 g/cm3
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
Solubility N/A
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Reactions to Avoid: Reacts violently with:
Materials to Avoid: Potassium, Strong bases.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Sulfur oxides, Lead/lead oxides.
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract.
Multiple Routes: May be harmful by inhalation, ingestion, or
skin absorption. Causes eye and skin irritation.
TARGET ORGAN(S) OR SYSTEM(S)
Blood. Kidneys. Nerves. Female reproductive system. Male
reproductive system.
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SIGNS AND SYMPTOMS OF EXPOSURE
Lead salts have been reported to cross the placenta and to
induce embryo- and feto- mortality. They also have teratogenic
effect in some animal species. No teratogenic effects have been
reported with exposure to organometallic lead compounds. Adverse
effects of lead on human reproduction, embryonic and fetal
development, and postnatal (e.g., mental) development have been
reported. Excessive exposure can affect blood, nervous, and
digestive systems. The synthesis of hemoglobin is inhibited and
results in anemia. If left untreated, neuromuscular dysfunction,
possible paralysis, and encephalopathy can result. Additional
symptoms of overexposure include: joint and muscle pain,
weakness of the extensor muscles (frequently the hand and
wrist), headache, dizziness, abdominal pain, diarrhea,
constipation, nausea, vomiting, blue line on the gums, insomnia,
and metallic taste. High body levels produce increased
cerebrospinal pressure, brain damage, and stupor leading to coma
and often death.
CHRONIC EXPOSURE - MUTAGEN
Species: Human
Dose: 23 UMOL/L
Cell Type: leukocyte
Mutation test: Sister chromatid exchange
Species: Hamster
Dose: 5 UMOL/L
Cell Type: ovary
Mutation test: Sister chromatid exchange
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Result: May cause reproductive disorders.
Section 12 - Ecological Information
No data available.
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Bury in a landfill site approved for the disposal of chemical and
hazardous wastes. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: Environmentally hazardous
substances, solid, n.o.s.
UN#: 3077
Class: 9
Packing Group: Packing Group III
Hazard Label: Class 9
PIH: Not PIH
IATA
Proper Shipping Name: Environmentally hazardous
substance, solid, n.o.s
IATA UN Number: 3077
Hazard Class: 9
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Packing Group: III
Section 15 - Regulatory Information
EU DIRECTIVES CLASSIFICATION
Symbol of Danger: T N
Indication of Danger: Toxic. Dangerous for the environment.
R: 61 20/22 33 50/53 62
Risk Statements: May cause harm to the unborn child. Harmful by
inhalation and if swallowed. Danger of cumulative effects. Very
toxic to aquatic organisms, may cause long-term adverse effects
in the aquatic environment. Possible risk of impaired fertility.
S: 53 45 60 61
Safety Statements: Restricted to professional users. Attention -
Avoid exposure - obtain special instructions before use. In case
of accident or if you feel unwell, seek medical advice
immediately (show the label where possible). This material and
its container must be disposed of as hazardous waste. Avoid
release to the environment. Refer to special instructions/safety
data sheets.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Harmful.
Risk Statements: Irritating to eyes, respiratory system and
skin. Limited evidence of a carcinogenic effect. Harmful by
inhalation, in contact with skin and if swallowed.
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. In
case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible). Do not breathe
fumes. Wear suitable protective clothing, gloves, and eye/face
protection.
US Statements: Reproductive hazard. Target organ(s): Nerves.
Blood. Kidneys.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
NOTES: This product is subject to SARA section 313 reporting
requirements. This product is subject to SARA section 313
reporting requirements.
TSCA INVENTORY ITEM: Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
ALDRICH - 307734 www.sigma-aldrich.com Page 5
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
ALDRICH - 307734 www.sigma-aldrich.com Page 6
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