SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/19/2005
Date Updated: 04/04/2004
Version 1.9
Section 1 - Product and Company Information
Product Name SODIUM CHLORIDE, +80 MESH, REAGENT
GRADE, >=98%
Product Number 310166
Brand ALDRICH
Company Sigma-Aldrich
Street Address 3050 Spruce Street
City, State, Zip, Country SAINT LOUIS MO 63103 US
Technical Phone: 314 771 5765
Emergency Phone: 414 273 3850 Ext. 5996
Fax: 800 325 5052
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
SODIUM CHLORIDE 7647-14-5 No
Formula NaCl
Synonyms Common salt * Dendritis * Extra Fine 200 Salt *
Extra Fine 325 Salt * Halite * H.G. blending *
Natriumchlorid (German) * Purex * Rock salt *
Saline * Salt * Sea salt * Table salt * Top flake
* USP sodium chloride * White crystal
RTECS Number: VZ4725000
Section 3 - Hazards Identification
HMIS RATING
HEALTH: 0
FLAMMABILITY: 0
REACTIVITY: 0
NFPA RATING
HEALTH: 0
FLAMMABILITY: 0
REACTIVITY: 0
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
DERMAL EXPOSURE
In case of contact, immediately wash skin with soap and copious
amounts of water.
EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
Section 5 - Fire Fighting Measures
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Noncombustible. Use extinguishing media appropriate to
surrounding fire conditions.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Exercise appropriate precautions to minimize direct contact with
skin or eyes and prevent inhalation of dust.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Avoid inhalation. Avoid contact with eyes, skin,
and clothing. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep tightly closed.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Wear dust mask.
Hand: Protective gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
Section 9 - Physical/Chemical Properties
ALDRICH - 310166 www.sigma-aldrich.com Page 2
Appearance Physical State: Solid
Property Value At Temperature or Pressure
Molecular Weight 58.44 AMU
pH 7
BP/BP Range 1,413 掳C
MP/MP Range 801 掳C
Freezing Point N/A
Vapor Pressure 1 mmHg 865 掳C
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density 2.165 g/cm3
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Soluble.
Other Solvents: 36G/100ML @ 20 掳C
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Sodium/sodium oxides, Hydrogen
chloride gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Sodium chloride (NaCl) in contact with eyes can
cause irritation or redness due to abrasion.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
SIGNS AND SYMPTOMS OF EXPOSURE
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Ingestion of large amounts causes vomiting and diarrhea.
Dehydration and congestion may occur in internal organs.
Hypertonic salt solutions can produce inflammatory reactions in
the gastrointestinal tract.
TOXICITY DATA
Oral
Rat
3000 mg/kg
LD50
Inhalation
Rat
> 42,000 mg/m3
LC50
Oral
Mouse
4000 mg/kg
LD50
Intraperitoneal
Mouse
2602 MG/KG
LD50
Subcutaneous
Mouse
3 GM/KG
LD50
Intravenous
Mouse
645 MG/KG
LD50
Intracervical
Mouse
131 MG/KG
LD50
Skin
Rabbit
> 10000 mg/kg
LD50
IRRITATION DATA
Skin
Rabbit
50 mg
24H
Remarks: Mild irritation effect
Skin
Rabbit
500 mg
24H
Remarks: Mild irritation effect
Eyes
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Rabbit
100 mg
Remarks: Mild irritation effect
Eyes
Rabbit
100 mg
24H
Remarks: Moderate irritation effect
Eyes
Rabbit
10 mg
Remarks: Moderate irritation effect
CHRONIC EXPOSURE - TERATOGEN
Species: Rat
Dose: 1710 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (13D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus). Effects on Embryo or Fetus: Fetal death.
Specific Developmental Abnormalities: Musculoskeletal system.
Species: Mouse
Dose: 1900 MG/KG
Route of Application: Subcutaneous
Exposure Time: (11D PREG)
Result: Effects on Embryo or Fetus: Fetal death.
Species: Mouse
Dose: 1900 MG/KG
Route of Application: Subcutaneous
Exposure Time: (10D PREG)
Result: Specific Developmental Abnormalities: Musculoskeletal
system.
Species: Mouse
Dose: 2500 MG/KG
Route of Application: Subcutaneous
Exposure Time: (10D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).
CHRONIC EXPOSURE - MUTAGEN
Species: Human
Dose: 125 MMOL/L
Cell Type: fibroblast
Mutation test: DNA inhibition
Species: Rat
Route: Oral
Dose: 16800 MG/KG
Exposure Time: 4W
Mutation test: Unscheduled DNA synthesis
Species: Rat
Route: Oral
Dose: 400 MG/KG
Mutation test: Other mutation test systems
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Species: Rat
Route: Intraperitoneal
Dose: 2338 MG/KG
Mutation test: Cytogenetic analysis
Species: Mouse
Dose: 101 MMOL/L
Cell Type: lymphocyte
Mutation test: DNA damage
Species: Mouse
Dose: 57200 UMOL/L
Cell Type: lymphocyte
Mutation test: Mutation in mammalian somatic cells.
Species: Hamster
Dose: 4 GM/L
Cell Type: lung
Mutation test: Micronucleus test
Species: Hamster
Dose: 275 MMOL/L
Cell Type: ovary
Mutation test: DNA damage
Species: Hamster
Dose: 160 MMOL/L
Cell Type: ovary
Mutation test: Cytogenetic analysis
Species: Hamster
Dose: 7500 MG/L
Cell Type: lung
Mutation test: Cytogenetic analysis
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Woman
Dose: 27 MG/KG
Route of Application: Intraplacental
Exposure Time: (15W PREG)
Result: Effects on Fertility: Abortion.
Species: Rat
Dose: 145 GM/KG
Route of Application: Oral
Exposure Time: (7D PRE/1-22D PREG)
Result: Effects on Newborn: Delayed effects.
Species: Rat
Dose: 56400 MG/KG
Route of Application: Oral
Exposure Time: (5D PRE-21D POST)
Result: Maternal Effects: Postpartum. Effects on Newborn:
Biochemical and metabolic.
Species: Rat
Dose: 10 GM/KG
Route of Application: Intraperitoneal
Exposure Time: (17-20D PREG)
Result: Effects on Newborn: Behavioral.
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Species: Rat
Dose: 10 MG/KG
Route of Application: Parenteral
Exposure Time: (1D PRE)
Result: Maternal Effects: Ovaries, fallopian tubes.
Species: Rat
Dose: 500 MG/KG
Route of Application: Intrauterine
Exposure Time: (4D PREG)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea).
Species: Rat
Dose: 50 MG/KG
Route of Application: Intrauterine
Exposure Time: (6D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Species: Mouse
Dose: 13440 MG/KG
Route of Application: Subcutaneous
Exposure Time: (2-6D PREG)
Result: Effects on Fertility: Abortion.
Species: Monkey
Dose: 6 GM/KG
Route of Application: Intrauterine
Exposure Time: (18W PREG)
Result: Effects on Fertility: Abortion.
Species: Horse, donkey
Dose: 480 MG/KG
Route of Application: Intraplacental
Exposure Time: (45D PREG)
Result: Maternal Effects: Other effects. Endocrine:Estrogenic.
Effects on Embryo or Fetus: Fetal death.
Section 12 - Ecological Information
No data available.
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: None
Non-Hazardous for Transport: This substance is
considered to be non-hazardous for transport.
IATA
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Non-Hazardous for Air Transport: Non-hazardous for air
transport.
Section 15 - Regulatory Information
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
TSCA INVENTORY ITEM: Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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