SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/15/2005
Date Updated: 11/11/2004
Version 1.5
Section 1 - Product and Company Information
Product Name POTASSIUM PERMANGANATE, 99+%,
A.C.S. REAGENT
Product Number 223468
Brand ALDRICH
Company Sigma-Aldrich
Street Address 3050 Spruce Street
City, State, Zip, Country SAINT LOUIS MO 63103 US
Technical Phone: 314 771 5765
Emergency Phone: 414 273 3850 Ext. 5996
Fax: 800 325 5052
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
POTASSIUM PERMANGANATE 7722-64-7 Yes
Formula KMnO4
Synonyms Cairox * Chameleon mineral * C.I. 77755 * Condy's
crystals * Permanganate de potassium (French) *
Permanganate of potash * Potassio (permanganato
di) (Italian) * Potassium permanganate *
Potassium (permanganate de) (French)
RTECS Number: SD6475000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Oxidizing. Harmful. Dangerous for the environment.
Contact with combustible material may cause fire. Harmful if
swallowed. Very toxic to aquatic organisms, may cause long-term
adverse effects in the aquatic environment.
HMIS RATING
HEALTH: 1
FLAMMABILITY: 0
REACTIVITY: 3
SPECIAL HAZARD(S): Oxidizer
NFPA RATING
HEALTH: 1
FLAMMABILITY: 0
REACTIVITY: 3
SPECIAL HAZARD(S): Oxidizer
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
DERMAL EXPOSURE
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
Section 5 - Fire Fighting Measures
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Contact with other material may cause fire. May accelerate
combustion.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not get in eyes, on skin, on clothing. Avoid
prolonged or repeated exposure.
STORAGE
Suitable: Keep tightly closed. Keep away from combustible
materials, heat, sparks, and open flame.
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Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Government approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Remove and wash contaminated
clothing promptly.
EXPOSURE LIMITS, RTECS
Country Source Type Value
USA ACGIH TWA 0.2 MG(MN)/M3
USA MSHA Standard-air Ceiling co5 MG(MN)/M3
USA OSHA. PEL CL 5 MG(MN)/M3
New Zealand OEL
Remarks: check ACGIH TLV
Section 9 - Physical/Chemical Properties
Appearance Color: Deep violet
Form: Fine crystals
Property Value At Temperature or Pressure
Molecular Weight 158.04 AMU
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Freezing Point N/A
Vapor Pressure N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density 2.71 g/cm3
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
Solubility N/A
N/A = not available
Section 10 - Stability and Reactivity
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STABILITY
Stable: Stable.
Materials to Avoid: Strong reducing agents, Finely powdered
metals, Peroxides, Zinc, Copper.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Nature of decomposition products
not known.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.
SIGNS AND SYMPTOMS OF EXPOSURE
Men exposed to manganese dusts showed a decrease in fertility.
Chronic manganese poisoning primarily involves the central
nervous system. Early symptoms include languor, sleepiness and
weakness in the legs. A stolid mask-like appearance of the face,
emotional disturbances such as uncontrollable laughter and a
spastic gait with tendency to fall in walking are findings in
more advanced cases. High incidence of pneumonia has been found
in workers exposed to the dust or fume of some manganese
compounds. To the best of our knowledge, the chemical, physical,
and toxicological properties have not been thoroughly
investigated.
TOXICITY DATA
Oral
Woman
100 mg/kg
LDLO
Remarks: Vascular:BP lowering not charactertized in autonomic
section. Liver:Hepatitis (hepatocellular necrosis), diffuse.
Kidney, Ureter, Bladder:Changes in tubules (including acute
renal failure, acute tubular necrosis).
Oral
Human
143 mg/kg
LDLO
Remarks: Lungs, Thorax, or Respiration:Dyspnea.
Gastrointestinal:Other changes.
Oral
Rat
1090 mg/kg
LD50
Oral
Mouse
2157 mg/kg
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LD50
Remarks: Behavioral:Somnolence (general depressed activity).
Oral
Guinea pig
1151 mg/kg
LD50
Remarks: Behavioral:Somnolence (general depressed activity).
CHRONIC EXPOSURE - MUTAGEN
Species: Mouse
Route: Oral
Dose: 205 MG/KG
Exposure Time: 24H
Mutation test: Micronucleus test
Species: Mouse
Route: Oral
Dose: 718 MG/KG
Exposure Time: 7D
Mutation test: Cytogenetic analysis
Species: Mouse
Dose: 1 MMOL/L
Exposure Time: 48H
Cell Type: mammary gland
Mutation test: Cytogenetic analysis
Species: Mouse
Route: Oral
Dose: 513 MG/KG
Exposure Time: 5D
Mutation test: sperm
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 400 MG/KG
Route of Application: Intratesticular
Exposure Time: (1D MALE)
Result: Effects on Fertility: Male fertility index (e.g., #
males impregnating females per # males exposed to fertile
nonpregnant females).
Species: Mouse
Dose: 513 MG/KG
Route of Application: Oral
Exposure Time: (5D MALE)
Result: Paternal Effects: Spermatogenesis (including genetic
material, sperm morphology,motility, and count).
Species: Gerbil
Dose: 25 MG/KG
Route of Application: Intratesticular
Exposure Time: (1D MALE)
Result: Effects on Fertility: Male fertility index (e.g., #
males impregnating females per # males exposed to fertile
nonpregnant females).
Section 12 - Ecological Information
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No data available.
ACUTE ECOTOXICITY TESTS
Test Type: LC50 Fish
Species: Onchorhynchus mykiss (Rainbow trout)
Time: 96 h
Value: 0.3 - 0.60 mg/l
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: Potassium permanganate
UN#: 1490
Class: 5.1
Packing Group: Packing Group II
Hazard Label: Oxidizer
PIH: Not PIH
IATA
Proper Shipping Name: Potassium permanganate
IATA UN Number: 1490
Hazard Class: 5.1
Packing Group: II
Section 15 - Regulatory Information
EU DIRECTIVES CLASSIFICATION
Symbol of Danger: O Xn N
Indication of Danger: Oxidizing. Harmful. Dangerous for the
environment.
R: 8 22 50/53
Risk Statements: Contact with combustible material may cause
fire. Harmful if swallowed. Very toxic to aquatic organisms, may
cause long-term adverse effects in the aquatic environment.
S: 60 61
Safety Statements: This material and its container must be
disposed of as hazardous waste. Avoid release to the
environment. Refer to special instructions/safety data sheets.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Oxidizing. Harmful. Dangerous for the
environment.
Risk Statements: Contact with combustible material may cause
fire. Harmful if swallowed. Very toxic to aquatic organisms, may
cause long-term adverse effects in the aquatic environment.
Safety Statements: This material and its container must be
disposed of as hazardous waste.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: Yes
DEMINIMIS: 1 %
NOTES: This product is subject to SARA section 313 reporting
requirements - manganese compounds.
TSCA INVENTORY ITEM: Yes
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CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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