SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/20/2005
Date Updated: 03/09/2004
Version 1.2
Section 1 - Product and Company Information
Product Name PHTHALIC ACID, 99.5+%, A.C.S.
REAGENT
Product Number 402915
Brand ALDRICH
Company Sigma-Aldrich
Street Address 3050 Spruce Street
City, State, Zip, Country SAINT LOUIS MO 63103 US
Technical Phone: 314 771 5765
Emergency Phone: 414 273 3850 Ext. 5996
Fax: 800 325 5052
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
PHTHALIC ACID 88-99-3 No
Formula C8H6O4
Synonyms Acide phtalique (French) *
Benzene-1,2-dicarboxylic acid *
o-Benzenedicarboxylic acid *
1,2-Benzenedicarboxylic acid * o-Dicarboxybenzene
* Kyselina ftalova (Czech) * O-Phthalic acid
RTECS Number: TH9625000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Irritant.
Irritating to eyes, respiratory system and skin.
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of contact, immediately wash skin with soap and copious
amounts of water.
EYE EXPOSURE
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
Section 5 - Fire Fighting Measures
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
EXPOSURE HAZARD(S)
Material: Irritant.
Section 6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Avoid contact and inhalation. Do not get in eyes,
on skin, on clothing.
STORAGE
Suitable: Keep tightly closed. Store in a cool dry place.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Government approved respirator.
Hand: Rubber gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
Section 9 - Physical/Chemical Properties
Appearance Color: White
Form: Fine crystals
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Property Value At Temperature or Pressure
Molecular Weight 166.13 AMU
pH N/A
BP/BP Range N/A
MP/MP Range 210 掳C
Freezing Point N/A
Vapor Pressure N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density N/A
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
Solubility N/A
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract.
Multiple Routes: May be harmful by inhalation, ingestion, or
skin absorption. Causes eye and skin irritation.
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
TOXICITY DATA
Oral Oral
Mouse Mouse
2530 mg/kg 2530 mg/kg
LD50 LD50
Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Ataxia. Gastrointestinal:Hypermotility, diarrhea.
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Behavioral:Somnolence (general depressed activity).
Behavioral:Ataxia. Gastrointestinal:Hypermotility, diarrhea.
Intraperitoneal Intraperitoneal
Mouse Mouse
550 MG/KG 550 MG/KG
LD50 LD50
Remarks: Behavioral:Change in motor activity (specific assay).
Behavioral:Muscle contraction or spasticity. Lungs, Thorax, or
Respiration:Cyanosis. Behavioral:Change in motor activity
(specific assay). Behavioral:Muscle contraction or spasticity.
Lungs, Thorax, or Respiration:Cyanosis.
CHRONIC EXPOSURE - MUTAGEN
Species: Mouse
Route: Intraperitoneal
Dose: 200 MG/KG
Exposure Time: 5D
Mutation test: Dominant lethal test
Species: Mouse
Route: Intraperitoneal
Dose: 100 MG/KG
Mutation test: sperm
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 29810 MG/KG
Route of Application: Oral
Exposure Time: (7-16D PREG)
Result: Maternal Effects: Other effects. Effects on Embryo or
Fetus: Fetotoxicity (except death, e.g., stunted fetus).
Specific Developmental Abnormalities: Musculoskeletal system.
Section 12 - Ecological Information
No data available.
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Dissolve or mix the material with a combustible solvent and burn
in a chemical incinerator equipped with an afterburner and
scrubber. Observe all federal, state, and local environmental
regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: None
Non-Hazardous for Transport: This substance is
considered to be non-hazardous for transport.
IATA
Non-Hazardous for Air Transport: Non-hazardous for air
transport.
Section 15 - Regulatory Information
EU ADDITIONAL CLASSIFICATION
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Symbol of Danger: Xi
Indication of Danger: Irritant.
R: 36/37/38
Risk Statements: Irritating to eyes, respiratory system and skin.
S: 26 36
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
suitable protective clothing.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Irritant.
Risk Statements: Irritating to eyes, respiratory system and skin.
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
suitable protective clothing.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
TSCA INVENTORY ITEM: Yes Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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