MagMAX鈩? Lysis/Binding Solution Concentrate
AMBION, INC.
Catalog #: 8500
Material Safety Data Sheet
Section 1-Identification of Product
Catalog Number: 8500 For research Health: 2 Fire: 1 Stability: 1
use only.
Synonyms:
Contact Information
Ambion, Inc 2130 Woodward St. Austin, TX 78744-1832 Tel: +1 512 651 0200 US Toll-free Tel: 800 888 8804 E-
mail: techserv@ambion.com Web address www.ambion.com
Ambion (Europe) LTD Huntingdon, Cambidgeshire UK PE29 6XY Tel:+44 (0)1480 373 020 Fax: +44 (0)1480 373
010 E-mail: eurotech@ambion.com Web address: www.ambion.com
Emergency Contact: In Europe, call 112. In USA, call 911
Section 2-Composition/Information
Hazardous Ingredients (Specific) % CAS # R-Statement S-Statement
Trade Secret #1 40-80 Trade Secret R:20/21/22 S:36/37/39
R: 32
R:36/37/38
Trade Secret #2 1-30 Trade Secret N.A. N.A.
Section 3-Hazard Identification
Routes of Entry
Skin Contact Trade Secret #1: Causes irritation to skin. Symptoms include redness,
itching, and pain.
Trade Secret #2: Possible irritation on prolonged contact with moist
or sensitive areas of the skin.
Skin Absorption Trade Secret #1: Causes irritation to skin. Symptoms include redness,
itching, and pain.
Trade Secret #2: Possible irritation on prolonged contact with moist
or sensitive areas of the skin.
Eye Contact Trade Secret #1: Causes irritation, redness, and pain.
Trade Secret #2: No adverse effects expected but dust may cause
mechanical irritation.
Inhalation Trade Secret #1: Causes irritation to the respiratory tract. Symptoms
may include coughing, shortness of breath.
Trade Secret #2: Inhalation of large amounts of dust may cause
irritation to the respiratory tract.
Ingestion Trade Secret #1: May cause psychosis, vomiting, disorientation,
weakness, low blood pressure, convulsions and death which may be
delayed. The probable lethal dose is between 15-30 grams.
Trade Secret #2: Extremely large oral dosages may produce
gastrointestinal disturbances.
[Emergency Overview]
WARNING! HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN, EYES AND
RESPIRATORY TRACT.
WHMIS Symbols
N.A.
[Potential Health Effects]
Trade Secret #1: Poison by intraperitoneal route. When heated to decomposition it emits very toxic fumes of NOx,
CN-, and SOx.
Trade Secret #2: Poison by intravenous route. Moderately toxic by intraperitoneal route. When heated to
decomposition it emits toxic fumes of Na2O.
Section 4-First Aid Measures
Skin Contact Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes
while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy
contaminated shoes.
Eye Contact Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower eyelids. Get medical aid immediately. Do not allow victim to rub or keep eyes
closed.
Inhalation Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid. Do not use mouth-to-mouth resuscitation.
Ingestion Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
EHS-MSDS-Lysis/BindingSol.Conc.-8500-01 Page 1 of 4 030806
MagMAX鈩? Lysis/Binding Solution Concentrate
AMBION, INC.
Catalog #: 8500
Material Safety Data Sheet
Section 5-Fire Fighting Measures
Flammable Slightly flammable
Means of Extinction Use water spray, dry chemical, carbon dioxide, or
appropriate foam.
Flashpoint (oC) and Method Not Tested
Upper Flammable Limit (% by volume) Not Tested
Lower Flammable Limit (% by volume) Not Tested
Autoignition Temperature (oC) Not Tested
Explosion Data 鈥? Sensitivity to Impact Not Tested
Explosion Data 鈥? Sensitivity to Static Discharge Not Tested
Hazardous Combustion Products Toxic fumes of carbon monoxide, carbon dioxide, nitrogen
oxides, and sulfur oxides.
NFPA Health: 2 Fire: 1 Stability: 1
Section 6-Accidental Release Measures
Leak and Spill Procedures
Wash area with soap and water. Clean up spills immediately, observing precautions in the protective equipment
section. Sweep up, and then place into a suitable container for disposal. Avoid generating dusty conditions. Provide
ventilation.
Section 7-Handling and Storage
Handling Procedures and Wash thoroughly after handling. Wash hands before eating. Use with adequate
Equipment ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly
closed. Avoid ingestion and inhalation. Wash clothing before reuse.
Storage Requirements Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect
against physical damage. Isolate from incompatible substances.
Section 8-Exposure Control/Personal Protection
Exposure Limits
ACGIH TLV Not Listed
OSHA PEL Not Listed
Other (specify) Not Listed
Engineering Controls (specific)
General Facilities storing or utilizing this material should be equipped with an eyewash
facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Local Exhaust A system of local and/or general exhaust is recommended to keep employee
exposures as low as possible. Local exhaust ventilation is generally preferred
because it can control the emissions of the contaminant at its source, preventing
dispersion of it into the general work area. Please refer to the ACGIH document,
Industrial Ventilation, A Manual of Recommended Practices, most recent
edition, for details.
Other N.A.
Personal Protective Equipment (specific)
Gloves Wear impervious gloves.
Respirator A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed
whenever workplace conditions warrant a respirator's use.
Eye Wear appropriate protective eyeglasses or chemical safety goggles as described
by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European
Standard EN166. Maintain eye wash fountain and quick-drench facilities in work
area.
Footwear Wear closed toe shoes.
Clothing Wear appropriate protective clothing to prevent skin exposure.
Other N.A.
Section 9-Physical and Chemical Properties
Physical State Liquid
Odor and Appearance None/Clear
Odor Threshold (ppm) Not Tested
Specific Gravity Not Tested
Vapor Density (Air=1) Not Tested
Vapor Pressure (mmHg) Not Tested
Evaporation Rate Not Tested
EHS-MSDS-Lysis/BindingSol.Conc.-8500-01 Page 2 of 4 030806
MagMAX鈩? Lysis/Binding Solution Concentrate
AMBION, INC.
Catalog #: 8500
Material Safety Data Sheet
Boiling Point (oC) Not Tested
Freezing Point (oC) Not Tested
pH 7.0
Coefficient of Water/Oil Distribution Not Tested
[Solubility in Water] Not Tested
Section 10-Stability and Reactivity
Chemical Stability Stable under ordinary conditions of use and storage.
Incompatible with other substances Iron, strong oxidizing agents, reducing agents, bases, strong acids.
Reactivity Not Tested
Hazardous Decomposition Products Trade Secret #1: Burning may produce fumes of cyanide, carbon
monoxide, carbon dioxide, nitrogen oxides and sulfur oxides.
Heating to decomposition or contact with acids or acid vapors can
liberate poisonous cyanide vapors.
Trade Secret #2: Carbon dioxide and carbon monoxide may form
when heated to decomposition.
Section 11-Toxicological Information
Acute Effects Trade Secret #1: Harmful if swallowed, inhaled, or absorbed through skin.
Material is irritating to mucous membranes and upper respiratory tract.
Trade Secret #2: May be harmful by inhalation, ingestion, or skin absorption.
May cause eye irritation. May cause skin irritation.
Chronic Effects Trade Secret #1: Prolonged or repeated skin exposure may cause dermatitis.
Repeated ingestion of small amounts may cause weakness, confusion, central
nervous system effects, nausea and skin eruptions.
Irritancy of Product Eyes, skin, respiratory, gastrointestinal system.
Skin Sensitization Not Tested
Respiratory Sensitization Not Tested
Trade Secret #1 LD50 Intraperitoneal Mouse: 300 mg/kg
Trade Secret #2 LC50 Not Tested
Trade Secret #1 LD50 IPR-Rat 1548mg/kg
Trade Secret #2 LC50 Not Tested
Carcinogenicity
IARC (1,2A, or 2B) Not Listed
ACGIH (A1, A2, or A3) Not Listed
Reproductive Toxicity Not Listed
Teratogenicity Not Listed
Embryotoxicity Not Listed
Mutagenicity Not Listed
Name of Synergistic Not Listed
Products/Effects
Section 12-Ecological Information
Aquatic Toxicity Not Tested
Section 13-Disposal Considerations
Waste Disposal Chemical waste generators must determine whether a discarded chemical is
classified as a hazardous waste. US EPA guidelines for the classification
determination are listed in 40 CFR Parts 261.3. Additionally, waste generators
must consult state and local hazardous waste regulations to ensure complete and
accurate classification.
Section 14-Transport Information
Special Shipping Information
PIN Not Listed
TDG Not Listed
[DOT] Not Listed
[IMO] Not Listed
[ICAO] Not Listed
Section 15-Regulatory Information
[WHMIS Classification] Not Listed
[OSHA] Not Listed
[SARA] Trade Secret #1- SARA Section 311/312 Inventory reporting: Yes.
[TSCA] Trade Secret #1 is reported in EPA TSCA Inventory.
Trade Secret #2 is reported in EPA TSCA Inventory.
EHS-MSDS-Lysis/BindingSol.Conc.-8500-01 Page 3 of 4 030806
MagMAX鈩? Lysis/Binding Solution Concentrate
AMBION, INC.
Catalog #: 8500
Material Safety Data Sheet
R:20/21 Harmful by inhalation, in contact with skin and if swallowed.
R: 32 Contact with acids liberates very toxic gas.
R:36/37/38 Irritating to eyes, respiratory system and skin.
S:36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
Section 16-Other Information
This bulletin is for your guidance and is based upon information and tests believed to be reliable. Ambion makes no
guarantee of the accuracy or completeness of the data and shall not be liable for any damages thereto. The data are
offered solely for your consideration, investigation, and verification. These suggestions should not be confused with
state, municipal, or insurance requirements, or with national safety codes and constitute no warranty. Any use of
these data and information must be determined by the user to be in accordance with applicable federal, state, and local
regulations.
EHS-MSDS-Lysis/BindingSol.Conc.-8500-01 Page 4 of 4 030806
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