FRUCTOSE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 17451
NC317TCP Version No:2.0
CD 2007/3 Page 1 of 9
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
FRUCTOSE
SYNONYMS
C6-H12-O6, "fruit sugar", fructosteril, arabino-2-hexulose, arabino-2-hexulose, D(
-)fructose, beta-D-fructopyranose, beta-D-fructopyranose, fructose-d, "fructopyranose,
beta-D-", "fructopyranose, beta-D-", D-fructose, D-fructose, laevulose, levulose,
levugen, frutabs, laevoral, laevosan
PRODUCT USE
Used in foods and medicines as a preservative and sweetener.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Dandenong South
Victoria 3175
Telephone: 03 8795 8000
Emergency Tel: 1300 131 001
Fax: 03 8795 8099
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
NON-HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to the Criteria of
NOHSC, and the ADG Code.
FRUCTOSE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 17451
NC317TCP Version No:2.0
CD 2007/3 Page 2 of 9
Section 2 - HAZARDS IDENTIFICATION
POISONS SCHEDULE
None
RISK SAFETY
None under normal operating conditions. None under normal operating conditions.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
fructose 7660-25-5 100
Section 4 - FIRST AID MEASURES
SWALLOWED
路 Immediately give a glass of water.
路 First aid is not generally required. If in doubt, contact a Poisons Information Centre
or a doctor.
EYE
If this product comes in contact with the eyes:
路 Wash out immediately with fresh running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 If pain persists or recurs seek medical attention.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
SKIN
Brush off dust. If skin or hair contact occurs:
路 Flush skin and hair with running water (and soap if available).
路 Seek medical attention in event of irritation.
INHALED
路 If fumes or combustion products are inhaled remove from contaminated area.
路 Other measures are usually unnecessary.
or 路 If dust is inhaled, remove from contaminated area.
路 Encourage patient to blow nose to ensure clear passage of breathing.
路 If irritation or discomfort persists seek medical attention.
NOTES TO PHYSICIAN
Treat symptomatically.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 Water spray or fog.
路 Foam.
路 Dry chemical powder.
路 BCF (where regulations permit).
路 Carbon dioxide.
FIRE FIGHTING
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Wear breathing apparatus plus protective gloves for fire only.
路 Prevent, by any means available, spillage from entering drains or water courses.
FRUCTOSE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 17451
NC317TCP Version No:2.0
CD 2007/3 Page 3 of 9
Section 5 - FIRE FIGHTING MEASURES
路 Use fire fighting procedures suitable for surrounding area.
路 DO NOT approach containers suspected to be hot.
路 Cool fire exposed containers with water spray from a protected location.
路 If safe to do so, remove containers from path of fire.
路 Equipment should be thoroughly decontaminated after use.
FIRE/EXPLOSION HAZARD
路 Combustible.
路 Slight fire hazard when exposed to heat or flame.
路 Heating may cause expansion or decomposition leading to violent rupture of containers.
路 On combustion, may emit toxic fumes of carbon monoxide (CO).
路 May emit acrid smoke.
路 Mists containing combustible materials may be explosive.
NOTE: Burns with intense heat. Produces melting, flowing, burning liquid and dense acrid
black smoke.
Other combustion products include: carbon dioxide (CO2).
FIRE INCOMPATIBILITY
Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine
bleaches, pool chlorine etc. as ignition may result.
Avoid creating dust - may present dust explosion hazard. Dry dust can be
electrostatically charged by turbulence, pneumatic transport, pouring, in exhaust
ducts and during transport. Build-up of electrostatic charge may be prevented by
grounding.
HAZCHEM: None
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
路 Remove all ignition sources.
路 Clean up all spills immediately.
路 Avoid contact with skin and eyes.
路 Control personal contact by using protective equipment.
路 Use dry clean up procedures and avoid generating dust.
路 Place in a suitable labelled container for waste disposal.
MAJOR SPILLS
No smoking, naked lights or ignition sources.
路 Clear area of personnel and move upwind.
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Control personal contact by using protective equipment and dust respirator.
路 Prevent spillage from entering drains, sewers or water courses.
路 Avoid generating dust.
路 Sweep, shovel up. Recover product wherever possible.
路 Put residues in labelled plastic bags or other containers for disposal.
路 If contamination of drains or waterways occurs, advise emergency services.
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
Avoid smoking, naked lights or ignition sources.
FRUCTOSE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 17451
NC317TCP Version No:2.0
CD 2007/3 Page 4 of 9
Section 7 - HANDLING AND STORAGE
路 Limit all unnecessary personal contact.
路 Wear protective clothing when risk of exposure occurs.
路 Use in a well-ventilated area.
路 When handling DO NOT eat, drink or smoke.
路 Always wash hands with soap and water after handling.
路 Avoid physical damage to containers.
路 Use good occupational work practice.
路 Observe manufacturer's storing and handling recommendations.
SUITABLE CONTAINER
Multi-ply paper bag with sealed plastic liner or heavy gauge plastic bag.
NOTE: Bags should be stacked, blocked, interlocked, and limited in height so that they
are stable and secure against sliding or collapse. Check that all containers are clearly
labelled and free from leaks. Packing as recommended by manufacturer.
STORAGE INCOMPATIBILITY
Materials for human consumption are to be protected from all possible contamination.
Avoid reaction with oxidising agents.
Avoid storage with reducing agents.
Avoid strong acids.
STORAGE REQUIREMENTS
路 Store in original containers.
路 Keep containers securely sealed.
路 No smoking, naked lights or ignition sources.
路 Store in a cool, dry, well-ventilated area.
路 Store away from incompatible materials and foodstuff containers.
路 Protect containers against physical damage and check regularly for leaks.
路 Observe manufacturer's storing and handling recommendations.
_____________________________________________________
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
+ + + + + +
_____________________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA mg/m鲁
_________ _________ _____
Australia Exposure Standards fructose (Inspirable dust (Not 10
specified))
MATERIAL DATA
These "dusts" have little adverse effect on the lungs and do not produce toxic effects or
organic disease. Although there is no dust which does not evoke some cellular response at
sufficiently high concentrations, the cellular response caused by P.N.O.C.s has the
following characteristics:
路 the architecture of the air spaces remain intact,
路 scar tissue (collagen) is not synthesised to any degree,
路 tissue reaction is potentially reversible.
FRUCTOSE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 17451
NC317TCP Version No:2.0
CD 2007/3 Page 5 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
Extensive concentrations of P.N.O.C.s may:
路 seriously reduce visibility,
路 cause unpleasant deposits in the eyes, ears and nasal passages,
路 contribute to skin or mucous membrane injury by chemical or mechanical action, per se,
or by the rigorous skin cleansing procedures necessary for their removal. [ACGIH]
This limit does not apply:
路 to brief exposures to higher concentrations
路 nor does it apply to those substances that may cause physiological impairment at lower
concentrations but for which a TLV has as yet to be determined.
This exposure standard applies to particles which
路 are insoluble or poorly soluble* in water or, preferably, in aqueous lung fluid (if
data is available) and
路 have a low toxicity (i.e.. are not cytotoxic, genotoxic, or otherwise chemically
reactive with lung tissue, and do not emit ionizing radiation, cause immune sensitization
, or cause toxic effects other than by inflammation or by a mechanism of lung overload).
PERSONAL PROTECTION
EYE
路 Safety glasses with side shields; or as required,
路 Chemical goggles.
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
Wear general protective gloves: i.e. Disposable polythene gloves or Cotton gloves or
Light weight rubber gloves, with Barrier cream preferably Safety footwear.
OTHER
路 Overalls.
路 Eyewash unit.
RESPIRATOR
Protection Factor Half- Face Respirator Full- Face Respirator Powered Air Respirator
10 x ES P1 Air- line* -- PAPR- P1 -
50 x ES Air- line** P2 PAPR- P2
100 x ES - P3 -
Air- line* -
100+ x ES - Air- line** PAPR- P3
* - Negative pressure demand ** - Continuous flow.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
FRUCTOSE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 17451
NC317TCP Version No:2.0
CD 2007/3 Page 6 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
Use in a well-ventilated area.
路 Local exhaust ventilation is required where solids are handled as powders or crystals;
even when particulates are relatively large, a certain proportion will be powdered by
mutual friction.
路 Exhaust ventilation should be designed to prevent accumulation and recirculation of
particulates in the workplace.
路 If in spite of local exhaust an adverse concentration of the substance in air could
occur, respiratory protection should be considered. Such protection might consist of:
(a): particle dust respirators, if necessary, combined with an absorption cartridge;
(b): filter respirators with absorption cartridge or canister of the right type;
(c): fresh-air hoods or masks
路 Build-up of electrostatic charge on the dust particle, may be prevented by bonding and
grounding.
路 Powder handling equipment such as dust collectors, dryers and mills may require
additional protection measures such as explosion venting.
Air contaminants generated in the workplace possess varying "escape" velocities which, in
turn, determine the "capture velocities" of fresh circulating air required to efficiently
remove the contaminant.
Type of Contaminant: Air Speed:
direct spray, spray painting in shallow booths, 1- 2.5 m/s (200- 500 f/min.)
drum filling, conveyer loading, crusher dusts,
gas discharge (active generation into zone of
rapid air motion)
grinding, abrasive blasting, tumbling, high 2.5- 10 m/s (500- 2000 f/min.)
speed wheel generated dusts (released at high
initial velocity into zone of very high rapid
air motion).
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood- local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
source. The air velocity at the extraction fan, for example, should be a minimum of 4-10
m/s (800-2000 f/min) for extraction of crusher dusts generated 2 metres distant from the
extraction point. Other mechanical considerations, producing performance deficits within
the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or used.
FRUCTOSE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 17451
NC317TCP Version No:2.0
CD 2007/3 Page 7 of 9
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Odourless, hard, white, dry crystals, lumps or powder with sweet taste. Soluble in water,
alcohol and ether. Taste is sweeter than sugar.
PHYSICAL PROPERTIES
Solid.
Mixes with water.
Molecular Weight: 180.18 Boiling Range (掳C): Not applicable.
Melting Range (掳C): 103 decomposes. Specific Gravity (water=1): Not available
Solubility in water (g/L): Soluble. pH (as supplied): Not applicable
pH (1% solution): 7 Vapour Pressure (kPa): Not applicable
Volatile Component (%vol): Not applicable Evaporation Rate: Not applicable
Relative Vapour Density (air=1): Not applicable Flash Point (掳C): Not available.
Lower Explosive Limit (%): Not available Upper Explosive Limit (%): Not available.
Autoignition Temp (掳C): Not available. Decomposition Temp (掳C): Not available.
State: Divided solid
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
路 Presence of incompatible materials.
路 Product is considered stable.
路 Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
Use as a food additive indicates good tolerance of small amounts, but excessive amounts
or overuse may bring irritant and/or harmful effects.
The material is. regarded as non-toxic if swallowed.
EYE
The dust is. mildly discomforting to the eyes.
SKIN
Not considered an irritant through normal use.
INHALED
The dust is. discomforting to the upper respiratory tract.
CHRONIC HEALTH EFFECTS
Primary route of exposure is usually by inhalation of generated dust.
Indicators are that short term exposure to the material by all routes is not harmful.
As with any chemical product, contact with unprotected bare skin; inhalation of vapour,
mist or dust in work place atmosphere; or ingestion in any form, should be avoided by
observing good occupational work practice.
FRUCTOSE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 17451
NC317TCP Version No:2.0
CD 2007/3 Page 8 of 9
Section 11 - TOXICOLOGICAL INFORMATION
TOXICITY AND IRRITATION
No significant acute toxicological data identified in literature search.
Use in food, and as food additive indicates high degree of tolerance.
Tumorigenic - equivocal tumorigenic agent by RTECS criteria.
Section 12 - ECOLOGICAL INFORMATION
No data for fructose.
Section 13 - DISPOSAL CONSIDERATIONS
路 Recycle wherever possible or consult manufacturer for recycling options.
路 Consult State Land Waste Management Authority for disposal.
路 Bury residue in an authorised landfill.
路 Recycle containers if possible, or dispose of in an authorised landfill.
Section 14 - TRANSPORTATION INFORMATION
HAZCHEM: None
NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS:UN, IATA,
IMDG
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: None
REGULATIONS
fructose (CAS: 7660-25-5) is found on the following regulatory lists;
Australia Exposure Standards
Australia Inventory of Chemical Substances (AICS)
Australia Therapeutic Goods Administration (TGA) Substances that may be used as active ingredients in Listed medicines
fructose (CAS: 57-48-7) is found on the following regulatory lists;
Australia Exposure Standards
Australia Inventory of Chemical Substances (AICS)
OECD Representative List of High Production Volume (HPV) Chemicals
Section 16 - OTHER INFORMATION
INGREDIENTS WITH MULTIPLE CAS NUMBERS
Ingredient Name CAS
fructose 7660- 25- 5, 57- 48- 7
Classification of the preparation and its individual components has drawn on official and
authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 12-May-2005
FRUCTOSE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 17451
NC317TCP Version No:2.0
CD 2007/3 Page 9 of 9
Section 16 - OTHER INFORMATION
Print Date: 20-Dec-2007
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