NEOPENTYL GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 31-Oct-2006 CHEMWATCH 35719
NC317TCP Version No:3
CD 2007/3 Page 1 of 10
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
NEOPENTYL GLYCOL
SYNONYMS
C5H12O2, "1, 3-propanediol, 2, 2-dimethyl-", "1, 3-propanediol, 2, 2-dimethyl-",
dimethylolpropane, "dimethyltrimethylene glycol", "2, 2-dimethyl-1, 3-propanediol", "2, 2
-dimethyl-1, 3-propanediol", Neol, "neopentylene glycol", "NPG alcohol"
PRODUCT USE
As polyol in alkyd resins, polyester resins for urethane foams and coatings.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Dandenong South
Victoria 3175
Telephone: 03 8795 8000
Emergency Tel: 1300 131 001
Fax: 03 8795 8099
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to the Criteria of
NOHSC, and the ADG Code.
NEOPENTYL GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 31-Oct-2006 CHEMWATCH 35719
NC317TCP Version No:3
CD 2007/3 Page 2 of 10
Section 2 - HAZARDS IDENTIFICATION
POISONS SCHEDULE
None
RISK SAFETY
Risk of serious damage to eyes. To clean the floor and all objects contaminated
by this material use water.
If swallowed IMMEDIATELY contact Doctor or
Poisons Information Centre (show this container
or label).
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
neopentyl glycol 126-30-7 > 99
Section 4 - FIRST AID MEASURES
SWALLOWED
路 Immediately give a glass of water.
路 First aid is not generally required. If in doubt, contact a Poisons Information Centre
or a doctor.
EYE
If this product comes in contact with the eyes:
路 Immediately hold eyelids apart and flush the eye continuously with running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 Continue flushing until advised to stop by the Poisons Information Centre or a doctor,
or for at least 15 minutes.
路 Transport to hospital or doctor without delay.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
SKIN
If skin or hair contact occurs:
路 Flush skin and hair with running water (and soap if available).
路 Seek medical attention in event of irritation.
INHALED
路 If fumes or combustion products are inhaled remove from contaminated area.
路 Other measures are usually unnecessary.
NOTES TO PHYSICIAN
Treat symptomatically.
NEOPENTYL GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 31-Oct-2006 CHEMWATCH 35719
NC317TCP Version No:3
CD 2007/3 Page 3 of 10
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 Water spray or fog.
路 Foam.
路 Dry chemical powder.
路 BCF (where regulations permit).
路 Carbon dioxide.
FIRE FIGHTING
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Wear breathing apparatus plus protective gloves.
路 Prevent, by any means available, spillage from entering drains or water courses.
路 Use water delivered as a fine spray to control fire and cool adjacent area.
路 DO NOT approach containers suspected to be hot.
路 Cool fire exposed containers with water spray from a protected location.
路 If safe to do so, remove containers from path of fire.
路 Equipment should be thoroughly decontaminated after use.
FIRE/EXPLOSION HAZARD
路 Combustible solid which burns but propagates flame with difficulty.
路 Avoid generating dust, particularly clouds of dust in a confined or unventilated space
as dusts may form an explosive mixture with air, and any source of ignition, i.e.
flame or spark, will cause fire or explosion. Dust clouds generated by the fine
grinding of the solid are a particular hazard; accumulations of fine dust may burn
rapidly and fiercely if ignited.
路 Dry dust can be charged electrostatically by turbulence, pneumatic transport, pouring,
in exhaust ducts and during transport.
路 Build-up of electrostatic charge may be prevented by bonding and grounding.
路 Powder handling equipment such as dust collectors, dryers and mills may require
additional protection measures such as explosion venting.
路 All movable parts coming in contact with this material should have a speed of less than
1-meter/sec.
Combustion products include: carbon monoxide (CO), carbon dioxide (CO2), other
pyrolysis products typical of burning organic material.
NOTE: Burns with intense heat. Produces melting, flowing, burning liquid and dense acrid
black smoke.
May emit corrosive fumes.
FIRE INCOMPATIBILITY
Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine
bleaches, pool chlorine etc. as ignition may result.
HAZCHEM: None
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
路 Clean up all spills immediately.
路 Avoid breathing dust and contact with skin and eyes.
路 Wear protective clothing, gloves, safety glasses and dust respirator.
路 Use dry clean up procedures and avoid generating dust.
路 Sweep up, shovel up or
路 Vacuum up (consider explosion-proof machines designed to be grounded during storage and
use).
路 Place spilled material in clean, dry, sealable, labelled container.
NEOPENTYL GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 31-Oct-2006 CHEMWATCH 35719
NC317TCP Version No:3
CD 2007/3 Page 4 of 10
Section 6 - ACCIDENTAL RELEASE MEASURES
MAJOR SPILLS
Moderate hazard.
路 CAUTION: Advise personnel in area.
路 Alert Emergency Services and tell them location and nature of hazard.
路 Control personal contact by wearing protective clothing.
路 Prevent, by any means available, spillage from entering drains or water courses.
路 Recover product wherever possible.
路 IF DRY: Use dry clean up procedures and avoid generating dust. Collect residues and
place in sealed plastic bags or other containers for disposal. IF WET: Vacuum/shovel up
and place in labelled containers for disposal.
路 ALWAYS: Wash area down with large amounts of water and prevent runoff into drains.
路 If contamination of drains or waterways occurs, advise Emergency Services.
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
路 Avoid all personal contact, including inhalation.
路 Wear protective clothing when risk of exposure occurs.
路 Use in a well-ventilated area.
路 Prevent concentration in hollows and sumps.
路 DO NOT enter confined spaces until atmosphere has been checked.
路 DO NOT allow material to contact humans, exposed food or food utensils.
路 Avoid contact with incompatible materials.
路 When handling, DO NOT eat, drink or smoke.
路 Keep containers securely sealed when not in use.
路 Avoid physical damage to containers.
路 Always wash hands with soap and water after handling.
路 Work clothes should be laundered separately. Launder contaminated clothing before re
-use.
路 Use good occupational work practice.
路 Observe manufacturer's storing and handling recommendations.
路 Atmosphere should be regularly checked against established exposure standards to ensure
safe working conditions are maintained.
SUITABLE CONTAINER
Multi-ply paper bag with sealed plastic liner or heavy gauge plastic bag.
NOTE: Bags should be stacked, blocked, interlocked, and limited in height so that they
are stable and secure against sliding or collapse. Check that all containers are clearly
labelled and free from leaks. Packing as recommended by manufacturer.
路 Lined metal can, lined metal pail/ can.
路 Plastic pail.
路 Polyliner drum.
路 Packing as recommended by manufacturer.
路 Check all containers are clearly labelled and free from leaks.
STORAGE INCOMPATIBILITY
Avoid reaction with oxidising agents.
STORAGE REQUIREMENTS
路 Store in original containers.
路 Keep containers securely sealed.
路 Store in a cool, dry, well-ventilated area.
路 Store away from incompatible materials and foodstuff containers.
路 Protect containers against physical damage and check regularly for leaks.
路 Observe manufacturer's storing and handling recommendations.
NEOPENTYL GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 31-Oct-2006 CHEMWATCH 35719
NC317TCP Version No:3
CD 2007/3 Page 5 of 10
Section 7 - HANDLING AND STORAGE
_____________________________________________________
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
+ X + X 0 +
_____________________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
The following materials had no OELs on our records
鈥? neopentyl glycol: CAS:126- 30- 7
MATERIAL DATA
It is the goal of the ACGIH (and other Agencies) to recommend TLVs (or their equivalent)
for all substances for which there is evidence of health effects at airborne
concentrations encountered in the workplace.
At this time no TLV has been established, even though this material may produce adverse
health effects (as evidenced in animal experiments or clinical experience). Airborne
concentrations must be maintained as low as is practically possible and occupational
exposure must be kept to a minimum.
NOTE: The ACGIH occupational exposure standard for Particles Not Otherwise Specified
(P.N.O.S) does NOT apply.
Sensory irritants are chemicals that produce temporary and undesirable side-effects on
the eyes, nose or throat. Historically occupational exposure standards for these
irritants have been based on observation of workers' responses to various airborne
concentrations. Present day expectations require that nearly every individual should be
protected against even minor sensory irritation and exposure standards are established
using uncertainty factors or safety factors of 5 to 10 or more. On occasion animal no
-observable-effect-levels (NOEL) are used to determine these limits where human results
are unavailable. An additional approach, typically used by the TLV committee (USA) in
determining respiratory standards for this group of chemicals, has been to assign ceiling
values (TLV C) to rapidly acting irritants and to assign short-term exposure limits (TLV
STELs) when the weight of evidence from irritation, bioaccumulation and other endpoints
combine to warrant such a limit. In contrast the MAK Commission (Germany) uses a five
-category system based on intensive odour, local irritation, and elimination half-life.
However this system is being replaced to be consistent with the European Union (EU)
Scientific Committee for Occupational Exposure Limits (SCOEL); this is more closely
allied to that of the USA.
OSHA (USA) concluded that exposure to sensory irritants can:
路 cause inflammation
路 cause increased susceptibility to other irritants and infectious agents
路 lead to permanent injury or dysfunction
路 permit greater absorption of hazardous substances and
路 acclimate the worker to the irritant warning properties of these substances thus
increasing the risk of overexposure.
PERSONAL PROTECTION
NEOPENTYL GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 31-Oct-2006 CHEMWATCH 35719
NC317TCP Version No:3
CD 2007/3 Page 6 of 10
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EYE
路 Safety glasses with side shields.
路 Chemical goggles.
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
Suitability and durability of glove type is dependent on usage. Factors such as:
路 frequency and duration of contact,
路 chemical resistance of glove material,
路 glove thickness and
路 dexterity,
are important in the selection of gloves.
Experience indicates that the following polymers are suitable as glove materials for
protection against undissolved, dry solids.
路 polychloroprene
路 nitrile rubber
路 butyl rubber
路 fluorocaoutchouc
路 polyvinyl chloride
Gloves should be examined for wear and/ or degradation constantly.
OTHER
路 Overalls.
路 P.V.C. apron.
路 Barrier cream.
路 Skin cleansing cream.
路 Eye wash unit.
RESPIRATOR
Protection Factor Half- Face Respirator Full- Face Respirator Powered Air Respirator
10 x ES P1 Air- line* -- PAPR- P1 -
50 x ES Air- line** P2 PAPR- P2
100 x ES - P3 -
Air- line* -
100+ x ES - Air- line** PAPR- P3
* - Negative pressure demand ** - Continuous flow.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
NEOPENTYL GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 31-Oct-2006 CHEMWATCH 35719
NC317TCP Version No:3
CD 2007/3 Page 7 of 10
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
ENGINEERING CONTROLS
路 Local exhaust ventilation is required where solids are handled as powders or crystals;
even when particulates are relatively large, a certain proportion will be powdered by
mutual friction.
路 Exhaust ventilation should be designed to prevent accumulation and recirculation of
particulates in the workplace.
路 If in spite of local exhaust an adverse concentration of the substance in air could
occur, respiratory protection should be considered. Such protection might consist of:
(a): particle dust respirators, if necessary, combined with an absorption cartridge;
(b): filter respirators with absorption cartridge or canister of the right type;
(c): fresh-air hoods or masks
路 Build-up of electrostatic charge on the dust particle, may be prevented by bonding and
grounding.
路 Powder handling equipment such as dust collectors, dryers and mills may require
additional protection measures such as explosion venting.
Air contaminants generated in the workplace possess varying "escape" velocities which, in
turn, determine the "capture velocities" of fresh circulating air required to efficiently
remove the contaminant.
Type of Contaminant: Air Speed:
direct spray, spray painting in shallow booths, 1- 2.5 m/s (200- 500 f/min.)
drum filling, conveyer loading, crusher dusts,
gas discharge (active generation into zone of
rapid air motion)
grinding, abrasive blasting, tumbling, high 2.5- 10 m/s (500- 2000 f/min.)
speed wheel generated dusts (released at high
initial velocity into zone of very high rapid
air motion).
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood- local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
source. The air velocity at the extraction fan, for example, should be a minimum of 4-10
m/s (800-2000 f/min) for extraction of crusher dusts generated 2 metres distant from the
extraction point. Other mechanical considerations, producing performance deficits within
the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or used.
NEOPENTYL GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 31-Oct-2006 CHEMWATCH 35719
NC317TCP Version No:3
CD 2007/3 Page 8 of 10
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
White free flowing combustible powder; soluble in water (830 g/l, 20 C). No odour. Soluble
in glycerol and glycols.
PHYSICAL PROPERTIES
Solid.
Mixes with water.
Molecular Weight: 104.17 Boiling Range (掳C): 210
Melting Range (掳C): 93- 94; 125- 130 Specific Gravity (water=1): 0.98
Solubility in water (g/L): Soluble pH (as supplied): Not applicable
pH (1% solution): Not applicable Vapour Pressure (kPa): Negligible
Volatile Component (%vol): Nil Evaporation Rate: Non Volatile
Relative Vapour Density (air=1): 3.6 Flash Point (掳C): 107
Lower Explosive Limit (%): 1.37 @ 150C Upper Explosive Limit (%): 18.8 @ 177C
Autoignition Temp (掳C): 375 Decomposition Temp (掳C): Not available
State: Divided solid Viscosity: Not Available
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
Product is considered stable and hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
Although ingestion is not thought to produce harmful effects (as classified under EC
Directives), the material may still be damaging to the health of the individual,
following ingestion, especially where pre-existing organ (e.g. liver, kidney) damage is
evident. Present definitions of harmful or toxic substances are generally based on doses
producing mortality rather than those producing morbidity (disease, ill-health).
Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational
setting however, ingestion of insignificant quantities is not thought to be cause for
concern.
EYE
If applied to the eyes, this material causes severe eye damage.
SKIN
The material is not thought to produce adverse health effects or skin irritation
following contact (as classified by EC Directives using animal models). Nevertheless,
good hygiene practice requires that exposure be kept to a minimum and that suitable
gloves be used in an occupational setting.
INHALED
The material is not thought to produce adverse health effects or irritation of the
respiratory tract (as classified by EC Directives using animal models). Nevertheless,
good hygiene practice requires that exposure be kept to a minimum and that suitable
control measures be used in an occupational setting.
Not normally a hazard due to non-volatile nature of product.
NEOPENTYL GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 31-Oct-2006 CHEMWATCH 35719
NC317TCP Version No:3
CD 2007/3 Page 9 of 10
Section 11 - TOXICOLOGICAL INFORMATION
CHRONIC HEALTH EFFECTS
Long term exposure to high dust concentrations may cause changes in lung function i.e.
pneumoconiosis; caused by particles less than 0.5 micron penetrating and remaining in the
lung. Prime symptom is breathlessness; lung shadows show on X-ray.
Long-term exposure to the product is not thought to produce chronic effects adverse to
the health (as classified by EC Directives using animal models); nevertheless exposure by
all routes should be minimised as a matter of course.
TOXICITY AND IRRITATION
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (rat) LDLo: 3200 mg/kg Skin (rabbit): non- irritating *
Oral (Rat) LD50: >6400 mg/kg* Mucous membrane:
Irritant *
Dermal (Guinea pig) LD50: >4000 mg/kg *
No sensitising effect *
No experimental evidence available for genotoxicity in vitro (Ames test
negative) *
* BASF MSDS
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish LC50 (48 h): Leuciscus idus >500 mg/l
Daphnia LC50 (48 h): >500 mg/l
Aquatic plants EC50 (72 h): Desmodesmus subspicatus >500 mg/l
Effect on activated sludge:
Inhibition of degradation activity in activated sludge is not anticipated during
correct introduction of low concentrations.
Persistence and degradability:
Elimination information.
Degree of elimination >90% OECD 302B; ISO 9888; 88/302/EEC, Part C DOC reduction
Easily eliminated from water.
Section 13 - DISPOSAL CONSIDERATIONS
路 Recycle wherever possible.
路 Consult manufacturer for recycling options or consult local or regional waste
management authority for disposal if no suitable treatment or disposal facility can be
identified.
路 Dispose of by: Burial in a licenced land-fill or Incineration in a licenced apparatus
(after admixture with suitable combustible material)
路 Decontaminate empty containers. Observe all label safeguards until containers are
cleaned and destroyed.
Section 14 - TRANSPORTATION INFORMATION
HAZCHEM: None
NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS:UN, IATA,
IMDG
NEOPENTYL GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 31-Oct-2006 CHEMWATCH 35719
NC317TCP Version No:3
CD 2007/3 Page 10 of 10
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: None
REGULATIONS
neopentyl glycol (CAS: 126-30-7) is found on the following regulatory lists;
Australia High Volume Industrial Chemical List (HVICL)
Australia Inventory of Chemical Substances (AICS)
OECD Representative List of High Production Volume (HPV) Chemicals
Section 16 - OTHER INFORMATION
Classification of the preparation and its individual components has drawn on official and
authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 31-Oct-2006
Print Date: 2-Jan-2008
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