ISOBUTANOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 23-Jun-2005 CHEMWATCH 1212
A317TC CD 2006/2 Page 1 of 13
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
ISOBUTANOL
SYNONYMS
C4-H10-O, (CH3)2-CH-CH2-OH, isobutanol, isopropylcarbinol, "2-methyl propanol",
2-methyl-1-propanol, "2-methyl propan-1-ol", "2-methylpropyl alcohol",
"1-propanol, 2-methyl-", 1-hydroxymethylpropane, "isobutyl alcohol", IBA
PROPER SHIPPING NAME
ISOBUTANOL (ISOBUTYL ALCOHOL)
Edit
PRODUCT USE
As a solvent for varnish and paint removers, an intermediate for amino coating
resins and as a substitute for n-butanol.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Quantum Industrial Park
Dandenong South VIC 3175
Australia
Telephone: 1300 782 688
Emergency Tel: 1300 131 001
Fax: 1300 782 699
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. DANGEROUS GOODS. According to the
ISOBUTANOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 23-Jun-2005 CHEMWATCH 1212
A317TC CD 2006/2 Page 2 of 13
Section 2 - HAZARDS IDENTIFICATION
Criteria of NOHSC, and the ADG Code.
POISONS SCHEDULE
None
RISK
Flammable.
Harmful by inhalation.
Irritating to respiratory system and skin.
Risk of serious damage to eyes.
HARMFUL-May cause lung damage if swallowed.
Vapours may cause drowsiness and dizziness.
Ingestion may produce health damage*.
* (limited evidence).
SAFETY
Do not breathe gas/fumes/vapour/spray.
Use only in well ventilated areas.
Keep container in a well ventilated place.
Keep container tightly closed.
Take off immediately all contaminated clothing.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
isobutanol 78-83-1 >99
Section 4 - FIRST AID MEASURES
SWALLOWED
鈥? For advice, contact a Poisons Information Centre or a doctor at once.
鈥? Urgent hospital treatment is likely to be needed.
鈥? If swallowed do NOT induce vomiting.
鈥? If vomiting occurs, lean patient forward or place on left side (head-down
position, if possible) to maintain open airway and prevent aspiration.
鈥? Observe the patient carefully.
鈥? Never give liquid to a person showing signs of being sleepy or with reduced
awareness; i.e. becoming unconscious.
鈥? Give water to rinse out mouth, then provide liquid slowly and as much as
casualty can comfortably drink.
鈥? Transport to hospital or doctor without delay.
EYE
If this product comes in contact with the eyes:
鈥? Immediately hold eyelids apart and flush the eye continuously with running
water.
鈥? Ensure complete irrigation of the eye by keeping eyelids apart and away from
eye and moving the eyelids by occasionally lifting the upper and lower lids.
鈥? Continue flushing until advised to stop by the Poisons Information Centre or a
doctor, or for at least 15 minutes.
ISOBUTANOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 23-Jun-2005 CHEMWATCH 1212
A317TC CD 2006/2 Page 3 of 13
Section 4 - FIRST AID MEASURES
鈥? Transport to hospital or doctor without delay.
鈥? Removal of contact lenses after an eye injury should only be undertaken by
skilled personnel.
SKIN
If skin contact occurs:
鈥? Immediately remove all contaminated clothing, including footwear
鈥? Flush skin and hair with running water (and soap if available).
鈥? Seek medical attention in event of irritation.
INHALED
鈥? If fumes or combustion products are inhaled remove from contaminated area.
鈥? Lay patient down. Keep warm and rested.
鈥? Prostheses such as false teeth, which may block airway, should be removed,
where possible, prior to initiating first aid procedures.
鈥? Apply artificial respiration if not breathing, preferably with a demand valve
resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if
necessary.
鈥? Transport to hospital, or doctor.
NOTES TO PHYSICIAN
To treat poisoning by the higher aliphatic alcohols:
鈥? Gastric lavage with copious amounts of water.
鈥? It may be beneficial to instill 60 ml of mineral oil into the stomach.
鈥? Oxygen and artificial respiration as needed.
鈥? Electrolyte balance: it may be useful to start 500 ml. M/6 sodium bicarbonate
intravenously but maintain a cautious and conservative attitude toward
electrolyte replacement unless shock or severe acidosis threatens.
鈥? To protect the liver, maintain carbohydrate intake by intravenous infusions of
glucose.
鈥? Haemodialysis if coma is deep and persistent. [GOSSELIN, SMITH HODGE: Clinical
Toxicology of Commercial Products, Ed 5)
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BASIC TREATMENT
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鈥? Establish a patent airway with suction where necessary.
鈥? Watch for signs of respiratory insufficiency and assist ventilation as
necessary.
鈥? Administer oxygen by non-rebreather mask at 10 t0 15 l/min.
鈥? Monitor and treat, where necessary, for shock.
鈥? Monitor and treat, where necessary, for pulmonary oedema.
鈥? Anticipate and treat, where necessary, for seizures.
鈥? DO NOT use emetics. Where ingestion is suspected rinse mouth and give up to
200 ml water (5 ml/kg recommended) for dilution where patient is able to
swallow, has a strong gag reflex and does not drool.
鈥? Give activated charcoal.
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ADVANCED TREATMENT
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鈥? Consider orotracheal or nasotracheal intubation for airway control in
unconscious patient or where respiratory arrest has occurred.
鈥? Positive-pressure ventilation using a bag-valve mask might be of use.
鈥? Monitor and treat, where necessary, for arrhythmias.
鈥? Start an IV D5W TKO. If signs of hypovolaemia are present use lactated Ringers
solution. Fluid overload might create complications.
鈥? If the patient is hypoglycaemic (decreased or loss of consciousness,
tachycardia, pallor, dilated pupils, diaphoresis and/or dextrose strip or
glucometer readings below 50 mg), give 50% dextrose.
鈥? Hypotension with signs of hypovolaemia requires the cautious administration of
fluids. Fluid overload might create complications.
鈥? Drug therapy should be considered for pulmonary oedema.
ISOBUTANOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 23-Jun-2005 CHEMWATCH 1212
A317TC CD 2006/2 Page 4 of 13
Section 4 - FIRST AID MEASURES
鈥? Treat seizures with diazepam.
鈥? Proparacaine hydrochloride should be used to assist eye irrigation.
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EMERGENCY DEPARTMENT
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鈥? Laboratory analysis of complete blood count, serum electrolytes, BUN,
creatinine, glucose, urinalysis, baseline for serum aminotransferases (ALT and
AST), calcium, phosphorus and magnesium, may assist in establishing a treatment
regime. Other useful analyses include anion and osmolar gaps, arterial blood
gases (ABGs), chest radiographs and electrocardiograph.
鈥? Positive end-expiratory pressure (PEEP)-assisted ventilation may be required
for acute parenchymal injury or adult respiratory distress syndrome.
鈥? Acidosis may respond to hyperventilation and bicarbonate therapy.
鈥? Haemodialysis might be considered in patients with severe intoxication.
鈥? Consult a toxicologist as necessary. BRONSTEIN, A.C. and CURRANCE, P.L.
EMERGENCY CARE FOR HAZARDOUS MATERIALS EXPOSURE: 2nd Ed. 1994.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
鈥? Alcohol stable foam.
Dry chemical powder.
Carbon dioxide.
FIRE FIGHTING
Alert Fire Brigade and tell them location and nature of hazard.
鈥? May be violently or explosively reactive.
鈥? Wear breathing apparatus plus protective gloves for fire only.
鈥? Prevent, by any means available, spillage from entering drains or water
courses.
Avoid spraying water onto liquid pools.
If safe to do so, switch off electrical equipment until vapour fire hazard is
removed.
DO NOT approach containers suspected to be hot.
If safe to do so, remove containers from path of fire.
Fight fire from a safe distance, with adequate cover.
Cool fire exposed containers with water spray from a protected location.
FIRE/EXPLOSION HAZARD
鈥? Liquid and vapour are flammable.
鈥? Moderate fire hazard when exposed to heat or flame.
鈥? Vapour forms an explosive mixture with air.
鈥? Moderate explosion hazard when exposed to heat or flame.
鈥? Vapour may travel a considerable distance to source of ignition.
鈥? Heating may cause expansion or decomposition leading to violent rupture of
containers.
鈥? On combustion, may emit toxic fumes of carbon monoxide (CO).
FIRE INCOMPATIBILITY
Avoid reaction with oxidising agents.
HAZCHEM
3[Y]
Personal Protective Equipment
Gloves, boots (chemical resistant).
Breathing apparatus.
ISOBUTANOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 23-Jun-2005 CHEMWATCH 1212
A317TC CD 2006/2 Page 5 of 13
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
鈥? Remove all ignition sources.
鈥? Clean up all spills immediately.
鈥? Avoid breathing vapours and contact with skin and eyes.
鈥? Control personal contact by using protective equipment.
鈥? Contain and absorb small quantities with vermiculite or other absorbent
material.
鈥? Wipe up.
鈥? Collect residues in a flammable waste container.
MAJOR SPILLS
Clear area of personnel and move upwind.
Alert Fire Brigade and tell them location and nature of hazard.
鈥? May be violently or explosively reactive.
鈥? Wear breathing apparatus plus protective gloves.
鈥? Prevent, by any means available, spillage from entering drains or water
courses.
No smoking, naked lights or ignition sources. Increase ventilation.
absorb vapour., Contain spill with sand, earth or vermiculite.
Use only spark-free shovels and explosion proof equipment.
Collect recoverable product into labelled containers for recycling.
Absorb remaining product with sand, earth or vermiculite.
Collect residues and seal in labelled drums for disposal.
Wash area down with large quantity of water and prevent runoff into drains.,
After clean up operations, decontaminate and launder all protective clothing and
equipment before storing and re-using.
If contamination of drains or waterways occurs, advise emergency services.
PROTECTIVE ACTIONS FOR SPILL
PROTECTIVE ACTION ZONE
half
evacuation
downwind
direction
distance
down wind distance
wind isolation
distance
direction
half
evacuation downwind
INITIAL direction distance
ISOLATION
ZONE
From IERG (Canada/Australia)
Isolation Distance 25 metres
Downwind Protection Distance 300 metres
IERG Number 17
FOOTNOTES
1 PROTECTIVE ACTION ZONE is defined as the area in which people are at risk
of harmful exposure. This zone assumes that random changes in wind direction
confines the vapour plume to an area within 30 degrees on either side of the
predominant wind direction, resulting in a crosswind protective action distance
equal to the downwind protective action distance.
2 PROTECTIVE ACTIONS should be initiated to the extent possible, beginning with
those closest to the spill and working away from the site in the downwind
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Issue Date: 23-Jun-2005 CHEMWATCH 1212
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Section 6 - ACCIDENTAL RELEASE MEASURES
direction. Within the protective action zone a level of vapour concentration
may exist resulting in nearly all unprotected persons becoming incapacitated
and unable to take protective action and/or incurring serious or irreversible
health effects.
3 INITIAL ISOLATION ZONE is determined as an area, including upwind of the
incident, within which a high probability of localised wind reversal may
expose nearly all persons without appropriate protection to life-threatening
concentrations of the material.
4 SMALL SPILLS involve a leaking package of 200 litres (55 US gallons) or less,
such as a drum (jerrican or box with inner containers). Larger packages leaking
less than 200 litres and compressed gas leaking from a small cylinder are also
considered "small spills".
LARGE SPILLS involve many small leaking packages or a leaking package of
greater than 200 litres, such as a cargo tank, portable tank or a "one-tonne"
compressed gas cylinder.
5 Guide 129 is taken from the US DOT emergency response guide book.
6 IERG information is derived from CANUTEC - Transport Canada.
EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)
The maximum airborne concentration below which it is believed that nearly all
individuals could be exposed for up to one hour WITHOUT experiencing or developing
life-threatening health effects is:
isobutanol 1600 ppm
irreversible or other serious effects or symptoms which could
impair an individual's ability to take protective action is:
isobutanol 250 ppm
other than mild, transient adverse effects
without perceiving a clearly defined odour is:
isobutanol 150 ppm
The threshold concentration below which most people.
will experience no appreciable risk of health effects:
isobutanol 100 ppm
American Industrial Hygiene Association (AIHA)
Ingredients considered according to the following cutoffs
Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0%
R50 >= 0.25% Corrosive (C) >= 5.0%
R51 >= 2.5%
else >= 10%
where percentage is percentage of ingredient found in the mixture
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
___________________________________________
+ X X X X +
___________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
ISOBUTANOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 23-Jun-2005 CHEMWATCH 1212
A317TC CD 2006/2 Page 7 of 13
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
鈥? Avoid all personal contact, including inhalation.
鈥? Wear protective clothing when risk of overexposure occurs.
鈥? Use in a well-ventilated area.
鈥? Prevent concentration in hollows and sumps.
鈥? DO NOT enter confined spaces until atmosphere has been checked.
鈥? Avoid smoking, naked lights or ignition sources.
鈥? Avoid generation of static electricity.
鈥? DO NOT use plastic buckets.
鈥? Earth all lines and equipment.
鈥? Use spark-free tools when handling.
鈥? Avoid contact with incompatible materials.
鈥? When handling, DO NOT eat, drink or smoke.
鈥? Keep containers securely sealed when not in use.
鈥? Avoid physical damage to containers.
鈥? Always wash hands with soap and water after handling.
鈥? Work clothes should be laundered separately.
鈥? Use good occupational work practice.
鈥? Observe manufacturer's storing and handling recommendations.
鈥? Atmosphere should be regularly checked against established exposure standards
to ensure safe working conditions.
SUITABLE CONTAINER
Packaging as recommended by manufacturer.
鈥? Check that containers are clearly labelled.
Glass container.
Plastic container.
Plastic drum.
Store in metal drums or safety cans.
STORAGE INCOMPATIBILITY
Avoid storage with oxidisers.
STORAGE REQUIREMENTS
Observe manufacturer's storing and handling recommendations.
Keep containers securely sealed.
No smoking, naked lights, heat or ignition sources.
Store in original containers in approved flammable liquid storage area.
Store in a cool, dry place.
Store in a well-ventilated area.
Store away from incompatible materials.
DO NOT use aluminium or galvanised containers.
DO NOT store in pits, depressions, basements or areas where vapours may be
trapped.
Protect containers against physical damage.
Check regularly for spills and leaks.
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA TWA STEL STEL Peak Peak
ppm mg/m鲁 ppm m5/m鲁 ppm mg/m鲁
_________________________ ________________ _____ _____ _____ _____ _____ _____
Australia Exposure isobutanol 50 152
Standards
ISOBUTANOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 23-Jun-2005 CHEMWATCH 1212
A317TC CD 2006/2 Page 8 of 13
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EMERGENCY EXPOSURE LIMITS
Material Original IDLH Original IDLH Revised IDLH Value Revised IDLH Value
Value (ppm) Value (mg/m3) (mg/m3) (ppm)
isobutanol 8,000 1,600
Odour Threshold Value: 0.66-40 ppm (detection), 1.8-53 ppm (recognition)
Although there do not appear to be reports of isobutyl alcohol causing
auditory impairment or vestibular damage in humans (as with n-butanol) the
recommended TLV-TWA recognises the slightly greater acute toxic potential
of isobutanol versus n-butanol. Exposure at or below this limit is thought
to significantly reduce the risk of skin irritation.
ODOUR SAFETY FACTOR (OSF)
OSF=31 (ISOBUTYL ALCOHOL)
Exposed individuals are reasonably expected to be warned, by smell, that the
Exposure Standard is being exceeded.
Odour Safety Factor (OSF) is determined to fall into either Class A or B.
The Odour Safety Factor (OSF) is defined as:
OSF= Exposure Standard (TWA) ppm/ Odour Threshold Value (OTV) ppm
Classification into classes follows:
Class OSF Description
A 550 Over 90% of exposed
individuals are aware by
smell that the Exposure
Standard (TLV-TWA for
example) is being
"reached " even when
distracted by working
activities
B 26-550 As """A""" for 50-90% of
persons being distracted
C 1-26 As """A""" for less than
50% of persons being
distracted
D 0.18-1 10-50% of persons aware
of being tested perceive
by smell that the
Exposure Standard is
being reached
E <0.18 As """D""" for less than
10% of persons aware of
being tested
.
PERSONAL PROTECTION
EYE
鈥? Safety glasses with side shields; or as required,
鈥? Chemical goggles.
鈥? Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens
ISOBUTANOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 23-Jun-2005 CHEMWATCH 1212
A317TC CD 2006/2 Page 9 of 13
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
or restrictions on use, should be created for each workplace or task. This
should include a review of lens absorption and adsorption for the class of
chemicals in use and an account of injury experience. Medical and first-aid
personnel should be trained in their removal and suitable equipment should be
readily available. In the event of chemical exposure, begin eye irrigation
immediately and remove contact lens as soon as practicable. Lens should be
removed at the first signs of eye redness or irritation - lens should be removed
in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
Neoprene gloves or Nitrile gloves.
PVC gloves.
Rubber gloves.
Safety footwear.
OTHER
鈥? Overalls.
鈥? Eyewash unit.
鈥? Barrier cream.
鈥? Skin cleansing cream.
Ensure there is ready access to a safety shower.
GLOVE SELECTION INDEX
Glove selection is based on a modified presentation of the:
"Forsberg Clothing Performance Index".
The effect(s) of the following substance(s) are taken into account in the
computer-generated selection: isobutanol
Protective Material CPI *.
________________________________
BUTYL A
BUTYL/NEOPRENE A
NITRILE+PVC A
VITON A
NEOPRENE A
NITRILE A
NATURAL+NEOPRENE B
PVC C
NATURAL RUBBER C
________________________________
* CPI - Chemwatch Performance Index
A: Best Selection
B: Satisfactory; may degrade after 4 hours continuous immersion
C: Poor to Dangerous Choice for other than short term immersion
NOTE: As a series of factors will influence the actual performance of the glove,
a final selection must be based on detailed observation. -
* Where the glove is to be used on a short term, casual or infrequent basis,
factors such as "feel" or convenience (e.g. disposability), may dictate a choice
of gloves which might otherwise be unsuitable following long-term or frequent
use. A qualified practitioner should be consulted.
RESPIRATOR
Selection of the Class and Type of respirator will depend upon the level of
breathing zone contaminant and the chemical nature of the contaminant.
Protection Factors (defined as the ratio of contaminant outside and inside the
mask) may also be important.
Breathing Zone Maximum Half-face Full-Face
Level ppm Protection Factor Respirator Respirator
(volume)
ISOBUTANOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 23-Jun-2005 CHEMWATCH 1212
A317TC CD 2006/2 Page 10 of 13
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
1000 10 A-AUS -
1000 50 - A-AUS
5000 50 Airline * -
5000 100 - A-2
10000 100 - A-3
100+ Airline**
* - Continuous Flow ** - Continuous-flow or positive pressure demand.
The local concentration of material, quantity and
conditions of use determine the type of personal
protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
Use in a well-ventilated area.
General exhaust is adequate under normal operating conditions.
If risk of inhalation or overexposure exists, wear SAA approved respirator or
work in fume hood.
Provide adequate ventilation in warehouse or closed storage areas.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Clear flammable liquid, does not mix with water. Strong, sweet and
disagreeable odour. Mixes with alcohol, ether and acetone.
PHYSICAL PROPERTIES
Liquid.
Molecular Weight: 74.2 Boiling Range (掳C): 108
Melting Range (掳C): -108 Specific Gravity (water=1): 0.80
Solubility in water (g/L): 4.5 % @ 20 C pH (as supplied): Not applicable
pH (1% solution): Not available. Vapour Pressure (kPa): 1.17 @ 20 C
Volatile Component (%vol): 100 approx. Evaporation Rate: 0.82 (BuAc=1)
Relative Vapour Density (air=1): 2.55 Flash Point (掳C): 28
Lower Explosive Limit (%): 1.2 Upper Explosive Limit (%): 10.9
Autoignition Temp (掳C): 440 Decomposition Temp (掳C): Not available
State: Liquid Viscosity: Not available
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
鈥? Presence of open flame.
Presence of heat source and ignition source.
Presence of incompatible materials.
Stable under normal storage conditions.
Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
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Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 23-Jun-2005 CHEMWATCH 1212
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Section 11 - TOXICOLOGICAL INFORMATION
ACUTE HEALTH EFFECTS
SWALLOWED
The liquid is highly discomforting and may be toxic if swallowed Ingestion may
result in nausea, abdominal irritation, pain and vomiting.
Overexposure to non-ring alcohols causes nervous system symptoms. These include
headache, muscle weakness and inco-ordination, giddiness, confusion, delirium
and coma. Digestive symptoms may include nausea, vomiting and diarrhoea.
Aspiration is much more dangerous than ingestion because lung damage can occur
and the substance is absorbed into the body. Alcohols with ring structures and
secondary and tertiary alcohols cause more severe symptoms, as do heavier
alcohols.
EYE
The liquid is extremely discomforting to the eyes and is capable of causing pain
and severe conjunctivitis. Corneal injury may develop, with possible permanent
impairment of vision, if not promptly and adequately treated.
The vapour is discomforting.
The material may produce severe irritation to the eye causing pronounced
inflammation. Repeated or prolonged exposure to irritants may produce
conjunctivitis.
SKIN
The liquid is discomforting to the skin and is capable of causing skin reactions
which may lead to dermatitis.
Most liquid alcohols appear to act as primary skin irritants in humans.
Significant percutaneous absorption occurs in rabbits but not apparently in man.
The material may cause skin irritation after prolonged or repeated exposure and
may produce on contact skin redness, swelling, the production of vesicles,
scaling and thickening of the skin.
INHALED
The vapour is highly discomforting to the upper respiratory tract.
Inhalation hazard is increased at higher temperatures.
Inhalation of high concentrations of gas/vapour causes lung irritation with
coughing and nausea, central nervous depression with headache and dizziness,
slowing of reflexes, fatigue and inco-ordination.
If exposure to highly concentrated solvent atmosphere is prolonged this may lead
to narcosis, unconsciousness, even coma and possible death.
CHRONIC HEALTH EFFECTS
Principal routes of exposure are usually by inhalation of vapour and skin
contact. Prolonged or continuous skin contact with the liquid may cause
defatting with drying, cracking, irritation and dermatitis following.
TOXICITY AND IRRITATION
TOXICITY IRRITATION
Oral (rat) LD50: 2460 mg/kg. Skin (rabbit): 20 mg/24h-Moderate
Dermal (rabbit) LD50: 3400 mg/kg. Eye (rabbit): 2 mg (open)-SEVERE
Eye (rabbit): 2 mg/24h - SEVERE
Section 12 - ECOLOGICAL INFORMATION
"Fish LC50 (96hr.) (mg/l):" 1.43E+06
"Algae IC50 (72hr.) (mg/l):" 290
"log Kow (Prager 1995):" 0.76
"log Kow (Sangster 1997):" 0.65
"log Pow (Verschueren 1983):" 0.65/0.83
BOD5: 60%
COD: 100%
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Chemwatch Material Safety Data Sheet (REVIEW)
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Section 12 - ECOLOGICAL INFORMATION
ThOD: 2.6
"Half-life Soil - High (hours):" 173
"Half-life Soil - Low (hours):" 43
"Half-life Air - High (hours):" 99.6
"Half-life Air - Low (hours):" 9.96
"Half-life Surface water - High (hours):" 173
"Half-life Surface water - Low (hours):" 43
"Half-life Ground water - High (hours):" 346
"Half-life Ground water - Low (hours):" 86
"Aqueous biodegradation - Aerobic - High (hours):" 173
"Aqueous biodegradation - Aerobic - Low (hours):" 43
"Aqueous biodegradation - Anaerobic - High (hours):" 692
"Aqueous biodegradation - Anaerobic - Low (hours):" 172
"Aqueous biodegradation - Removal secondary treatment - High (hours):" 99%
"Photooxidation half-life water - High (hours):" 1.90E+05
"Photooxidation half-life water - Low (hours):" 4813
"Photooxidation half-life air - High (hours):" 99.6
"Photooxidation half-life air - Low (hours):" 9.96
log Kow: 0.65-0.83
Half-life (hr) H2O surface water: 96
Henry's atm m鲁 /mol: 4.00E-04
BOD 5 if unstated: 0.07-1.66,64%
COD: 100%
ThOD: 2.6
Section 13 - DISPOSAL CONSIDERATIONS
鈥? Consult manufacturer for recycling options and recycle where possible .
鈥? Consult State Land Waste Management Authority for disposal.
鈥? Incinerate residue at an approved site.
鈥? Recycle containers if possible, or dispose of in an authorised landfill.
Section 14 - TRANSPORTATION INFORMATION
Labels Required
flammable liquid
HAZCHEM
3[Y]
Land Transport UNDG:
Dangerous Goods Class: 3 Subrisk: None
UN Number: 1212 Packing Group: III
Shipping Name:ISOBUTANOL (ISOBUTYL ALCOHOL)
Edit
Air Transport IATA:
ICAO/IATA Class: 3 ICAO/IATA Subrisk: None
UN/ID Number: 1212 Packing Group: III
ISOBUTANOL
Chemwatch Material Safety Data Sheet (REVIEW)
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Section 14 - TRANSPORTATION INFORMATION
ERG Code: 3L
Shipping Name: Isobutanol
Maritime Transport IMDG:
IMDG Class: 3 IMDG Subrisk: None
UN Number: 1212 Packing Group: III
EMS Number: None
Shipping Name: ISOBUTANOL (ISOBUTYL ALCOHOL)
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE
None
REGULATIONS
isobutanol (CAS: 78-83-1) is found on the following regulatory lists;
Australia Inventory of Chemical Substances (AICS)
International Council of Chemical Associations (ICCA) - High Production Volume
List
OECD Representative List of High Production Volume (HPV) Chemicals
Section 16 - OTHER INFORMATION
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Issue Date: 23-Jun-2005
Print Date: 28-Jun-2006
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