ISOPHTHALIC ACID

Chemwatch Material Safety Data Sheet (REVIEW)

Issue Date: 12-May-2005                                                                 CHEMWATCH 21970-1

A317TC                                                                                  CD 2006/2 Page 1 of 9







           Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION





PRODUCT NAME

        ISOPHTHALIC ACID



SYNONYMS

       C8-H6-O4, C6H4(COOH)2, "1, 3-benzenedicarboxylic acid", m-dicarboxybenzene,

       "m-benzenedicarboxylic acid", "benzene-1, 3-dicarboxylic acid", "m-phthalic

       acid", "iso-phthalic acid", IPA



PRODUCT USE

        Polyester, alkyd; polyurethane and other high polymers, plasticisers.



SUPPLIER

Company: Quantum Chemicals Pty Ltd

Address:

70 Quantum Close

Quantum Industrial Park

Dandenong South VIC 3175

Australia

Telephone: 1300 782 688

Emergency Tel: 1300 131 001

Fax: 1300 782 699





HAZARD RATINGS



      Flammability

          Toxicity

     Body Contact

         Reactivity

          Chronic



           SCALE:     Min/Nil=0       Low=1       Moderate=2       High=3       Extreme=4





           Section 2 - HAZARDS IDENTIFICATION





STATEMENT OF HAZARDOUS NATURE

        NON-HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to

        the Criteria of NOHSC, and the ADG Code.



POISONS SCHEDULE

         None

                                           ISOPHTHALIC ACID

Chemwatch Material Safety Data Sheet (REVIEW)

Issue Date: 12-May-2005                                                                       CHEMWATCH 21970-1

A317TC                                                                                        CD 2006/2 Page 2 of 9

                                                                               Section 2 - HAZARDS IDENTIFICATION



RISK

            Skin contact and/or ingestion may produce health damage*.

            Cumulative effects may result following exposure*.

            May possibly affect fertility*.

            * (limited evidence).



SAFETY

            Avoid exposure - obtain special instructions before use.

            Take off immediately all contaminated clothing.





            Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS



NAME                                                                                         CAS RN       %

isophthalic acid                                                                             121-91-5     >99





            Section 4 - FIRST AID MEASURES





SWALLOWED

       � Immediately give a glass of water.

       � First aid is not generally required. If in doubt, contact a Poisons

       Information Centre or a doctor.



EYE

            If this product comes in contact with the eyes:

            � Immediately hold eyelids apart and flush the eye continuously with running

            water.

            � Ensure complete irrigation of the eye by keeping eyelids apart and away from

            eye and moving the eyelids by occasionally lifting the upper and lower lids.

            � Continue flushing until advised to stop by the Poisons Information Centre or a

            doctor, or for at least 15 minutes.

            � Transport to hospital or doctor without delay.

            � Removal of contact lenses after an eye injury should only be undertaken by

            skilled personnel.



SKIN

            If skin contact occurs:

            � Immediately remove all contaminated clothing, including footwear

            � Flush skin and hair with running water (and soap if available).

            � Seek medical attention in event of irritation.



INHALED

            � If dust is inhaled, remove from contaminated area.

            � Encourage patient to blow nose to ensure clear passage of breathing.

            � If irritation or discomfort persists seek medical attention.



NOTES TO PHYSICIAN

         Treat symptomatically.





            Section 5 - FIRE FIGHTING MEASURES





EXTINGUISHING MEDIA

� Foam.

� Dry chemical powder.

� BCF (where regulations permit).

� Carbon dioxide.

� Water spray or fog - Large fires only.

                                           ISOPHTHALIC ACID

Chemwatch Material Safety Data Sheet (REVIEW)

Issue Date: 12-May-2005                                                                          CHEMWATCH 21970-1

A317TC                                                                                           CD 2006/2 Page 3 of 9

                                                                                Section 5 - FIRE FIGHTING MEASURES



FIRE FIGHTING

� Use water delivered as a fine spray to control fire and cool adjacent area.

� Do not approach containers suspected to be hot.

� Cool fire exposed containers with water spray from a protected location.

� If safe to do so, remove containers from path of fire.

� Equipment should be thoroughly decontaminated after use.



FIRE/EXPLOSION HAZARD

� Solid which exhibits difficult combustion or is difficult to ignite.

� Avoid generating dust, particularly clouds of dust in a confined or

unventilated space as dusts may form an explosive mixture with air, and any

source of ignition, i.e. flame or spark, will cause fire or explosion. Dust

clouds generated by the fine grinding of the solid are a particular hazard;

accumulations of fine dust may burn rapidly and fiercely if ignited

� Dry dust can also be charged electrostatically by turbulence, pneumatic

transport, pouring, in exhaust ducts and during transport.

� Build-up of electrostatic charge may be prevented by bonding and grounding.

� Powder handling equipment such as dust collectors, dryers and mills may

require additional protection measures such as explosion venting.

� All movable parts coming in contact with this material should have a speed of

less than 1-meter/sec.



FIRE INCOMPATIBILITY

Avoid contamination with oxidising agents i.e. nitrates, oxidising acids,

chlorine bleaches, pool chlorine etc. as ignition may result.



HAZCHEM

            None



Personal Protective Equipment

          Chemical splash suit.





            Section 6 - ACCIDENTAL RELEASE MEASURES





EMERGENCY PROCEDURES



      MINOR SPILLS

          � Clean up all spills immediately.

          � Avoid contact with skin and eyes.

          � Wear impervious gloves and safety glasses.

          � Use dry clean up procedures and avoid generating dust.

          � Sweep up or

          � Vacuum up (consider explosion-proof machines designed to be grounded during

          storage and use).

          � Place spilled material in clean, dry, sealable, labelled container.



      MAJOR SPILLS

          � Clear area of personnel and move upwind.

          � Alert Fire Brigade and tell them location and nature of hazard.

          � Control personal contact by using protective equipment and dust respirator.

          � Prevent spillage from entering drains, sewers or water courses.

          � Avoid generating dust.

          � Sweep, shovel up. Recover product wherever possible.

          � Put residues in labelled plastic bags or other containers for disposal.

          � If contamination of drains or waterways occurs, advise emergency services.



SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS

___________________________________________

                                        ISOPHTHALIC ACID

Chemwatch Material Safety Data Sheet (REVIEW)

Issue Date: 12-May-2005                                                                 CHEMWATCH 21970-1

A317TC                                                                                  CD 2006/2 Page 4 of 9

                                                                  Section 6 - ACCIDENTAL RELEASE MEASURES









  +     +      +       +      +       +

___________________________________________

+: May be stored together

O: May be stored together with specific preventions

X: Must not be stored together





            Personal Protective Equipment advice is contained in Section 8 of the MSDS.





            Section 7 - HANDLING AND STORAGE





PROCEDURE FOR HANDLING

       � Limit all unnecessary personal contact.

       � Wear protective clothing when risk of exposure occurs.

       � Use in a well-ventilated area.

       � When handling DO NOT eat, drink or smoke.

       � Always wash hands with soap and water after handling.

       � Avoid physical damage to containers.

       � Use good occupational work practice.

       � Observe manufacturer's storing and handling recommendations.



SUITABLE CONTAINER

         Multi ply paper bag with sealed plastic liner or heavy gauge plastic bag

         NOTE: Bags should be stacked, blocked, interlocked, and limited in height so

         that they are stable and secure against sliding or collapse. Check that all

         containers are clearly labelled and free from leaks. Packing as recommended by

         manufacturer.



STORAGE INCOMPATIBILITY

        Store away from strong oxidisers and strong alkalis.



STORAGE REQUIREMENTS

        � Keep dry.

        � Store in original containers.

        � Keep containers securely sealed.

        � No smoking, naked lights or ignition sources.

        � Store in a cool, dry, well-ventilated area.

        � Store away from incompatible materials.

        � Protect containers against physical damage.

        � Check regularly for leaks.

        � Observe manufacturer's storing and handling recommendations.





            Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION





EXPOSURE CONTROLS

The following materials had no OELs on our record under the following CAS or Chemwatch (CW) numbers

isophthalic acid: No data available for CAS:121-91-5





CEL TWA: 5 mg/m³ (compare WEEL TWA)

OEL STEL (Russia): 0.2 mg/m³ (skin)

MAK Section IIb: Substances for which no MAK values can be established

at present.

Exposure limits with "skin" notation indicate that vapour and liquid may be

                                         ISOPHTHALIC ACID

Chemwatch Material Safety Data Sheet (REVIEW)

Issue Date: 12-May-2005                                                       CHEMWATCH 21970-1

A317TC                                                                        CD 2006/2 Page 5 of 9

                                            Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION



absorbed through intact skin. Absorption by skin may readily exceed vapour

inhalation exposure. Symptoms for skin absorption are the same as for

inhalation. Contact with eyes and mucous membranes may also contribute to

overall exposure and may also invalidate the exposure standard.

Saturated vapour concentration: 10(exp-4) mg/m³ at 25 deg. C..

Isophthalic acid is essentially nontoxic in acute exposure. The only

significant adverse effect in long-term exposure studies was the formation

of kidney and bladder calculi in rats fed at relatively high doses. The

no-effect level seen in a 4-week inhalation study was at least 9.6 mg/m³.

Airborne concentrations necessary to produce kidney and bladder calculi

are estimated to be 1400 mg/m³ assuming 100% absorption. A workplace

environmental exposure level (WEEL) recommended by the AIHA is protective

against systemic effects.



PERSONAL PROTECTION









     EYE

           � Safety glasses.

           � Safety glasses with side shields.

           � Chemical goggles.

           � Contact lenses may pose a special hazard; soft contact lenses may absorb and

           concentrate irritants. A written policy document, describing the wearing of lens

           or restrictions on use, should be created for each workplace or task. This

           should include a review of lens absorption and adsorption for the class of

           chemicals in use and an account of injury experience. Medical and first-aid

           personnel should be trained in their removal and suitable equipment should be

           readily available. In the event of chemical exposure, begin eye irrigation

           immediately and remove contact lens as soon as practicable. Lens should be

           removed at the first signs of eye redness or irritation - lens should be removed

           in a clean environment only after workers have washed hands thoroughly. [CDC

           NIOSH Current Intelligence Bulletin 59].



     HANDS/FEET

         Rubber gloves.

         PVC gloves.

         Safety footwear.

         Rubber boots.



     OTHER

         Overalls.

         PVC apron.

         � Barrier cream.

         � Eyewash unit.

         Ensure there is ready access to a safety shower.



     RESPIRATOR

         Protection Factor           Half-Face           Full-Face         Powered Air

                                     Respirator          Respirator        Respirator

           10 x ES                   P1 Air-line*        --                PAPR-P1 -

           50 x ES                   Air-line**          P2                PAPR-P2

           100 x ES                  -                   P3                -

                                                         Air-line*         -

           100+ x ES                 -                   Air-line**        PAPR-P3

                                        ISOPHTHALIC ACID

Chemwatch Material Safety Data Sheet (REVIEW)

Issue Date: 12-May-2005                                                       CHEMWATCH 21970-1

A317TC                                                                        CD 2006/2 Page 6 of 9

                                            Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION





           * - Negative pressure demand ** - Continuous flow.



           The local concentration of material, quantity and

           conditions of use determine the type of personal

           protective equipment required.

           For further information consult site specific

           CHEMWATCH data (if available), or your

           Occupational Health and Safety Advisor.



ENGINEERING CONTROLS

        General exhaust is adequate under normal operating conditions. If risk of

        overexposure exists, wear SAA approved respirator. Correct fit is essential to

        obtain adequate protection. Provide adequate ventilation in warehouse or closed

        storage areas. Air contaminants generated in the workplace possess varying

        "escape" velocities which, in turn, determine the "capture velocities" of fresh

        circulating air required to effectively remove the contaminant.



           Type of Contaminant:                                  Air Speed:

           solvent " "vapours " degreasing "etc.                 0.25-0.5 m/s (50-100 f/min)

           " evaporating from tank (in still air)

           aerosols " fumes from pouring                         0.5-1 m/s (100-200 f/min.)

           "operations " intermittent container

           "filling " low speed conveyer

           "transfers " "welding " spray "drift "

           plating acid "fumes " pickling

           (released at low velocity into zone of

           active generation)

           direct "spray " spray painting in                     1-2.5 m/s (200-500 f/min)

           shallow "booths " drum "filling "

           conveyer "loading " crusher "dusts "

           gas discharge (active generation into

           zone of rapid air motion)

           grinding " abrasive "blasting "                       2.5-10 m/s (500-2000 f/min.)

           "tumbling " high speed wheel generated

           dusts (released at high initial

           velocity into zone of very high rapid

           air motion).



           Within each range the appropriate value depends on:



           Lower end of the range                               Upper end of the range

           1: Room air currents minimal or                      1: Disturbing room air currents

           favourable to capture

           2: Contaminants of low toxicity or of                2: Contaminants of high toxicity

           nuisance value only

           3: Intermittent, low production.                     3: High production, heavy use

           4: Large hood or large air mass in                   4: Small hood - local control only

           motion



           Simple theory shows that air velocity falls rapidly with distance away from the

           opening of a simple extraction pipe. Velocity generally decreases with the

           square of distance from the extraction point (in simple cases). Therefore the

           air speed at the extraction point should be adjusted, accordingly, after

           reference to distance from the contaminating source. The air velocity at the

           extraction fan, for example, should be a minimum of 1-2 m/s (200-400 f/min.) for

           extraction of solvents generated in a tank 2 meters distant from the extraction

           point. Other mechanical considerations, producing performance deficits within

           the extraction apparatus, make it essential that theoretical air velocities are

           multiplied by factors of 10 or more when extraction systems are installed or

           used.

                                          ISOPHTHALIC ACID

Chemwatch Material Safety Data Sheet (REVIEW)

Issue Date: 12-May-2005                                                                       CHEMWATCH 21970-1

A317TC                                                                                        CD 2006/2 Page 7 of 9





             Section 9 - PHYSICAL AND CHEMICAL PROPERTIES





APPEARANCE

        White crystalline powder; does not mix well with water

        (1:8000 cold, 1:460 boiling). Soluble in alcohol, glacial acetic acid.



PHYSICAL PROPERTIES

Solid.

Does not mix with water.

Sinks in water.



Molecular Weight: 166.14                                     Boiling Range (°C): Not available

Melting Range (°C): 341-343                                  Specific Gravity (water=1): 1.5 approx.

Solubility in water (g/L): Immiscible                        pH (as supplied): Not applicable

pH (1% solution): Not available                              Vapour Pressure (kPa): 1.5 x 10(-8)mm

Volatile Component (%vol): Negligible                        Evaporation Rate: Not applicable

Relative Vapour Density (air=1): 5.7 (est.)                  Flash Point (°C): >110

Lower Explosive Limit (%): Not available                     Upper Explosive Limit (%): Not available

Autoignition Temp (°C): 647.78                               Decomposition Temp (°C): Not available

State: Divided solid





             Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION





CONDITIONS CONTRIBUTING TO INSTABILITY

         � Presence of incompatible materials.

         � Product is considered stable.

         � Hazardous polymerisation will not occur.





             Section 11 - TOXICOLOGICAL INFORMATION





POTENTIAL HEALTH EFFECTS



ACUTE HEALTH EFFECTS



      SWALLOWED

          The material is moderately discomforting to the gastro-intestinal tract and may

          be harmful if swallowed in large quantity.

          The toxicity of phthalates is not excessive due to slow oral absorption and

          metabolism. Absorption is affected by fat in the diet. Repeated doses can cause

          cumulative toxic effects, and symptoms include an enlarged liver which often

          reverses if exposure is maintained. Carbohydrate metabolism is disrupted, and

          cholesterol and triglyceride levels in the blood falls. There can also be

          withering of the testicles. Some phthalates can increase the effects of

          antibiotics, thiamine (vitamin B1) and sulfonamides.



      EYE

             The dust may produce eye discomfort causing smarting, pain and redness.

             The material may be irritating to the eye, with prolonged contact causing

             inflammation. Repeated or prolonged exposure to irritants may produce

             conjunctivitis.



      SKIN

             The material may be mildly discomforting to the skin.

             Open cuts, abraded or irritated skin should not be exposed to this material.

                                        ISOPHTHALIC ACID

Chemwatch Material Safety Data Sheet (REVIEW)

Issue Date: 12-May-2005                                                                  CHEMWATCH 21970-1

A317TC                                                                                   CD 2006/2 Page 8 of 9

                                                                     Section 11 - TOXICOLOGICAL INFORMATION



     INHALED

         The dust may be discomforting to the upper respiratory tract.

         Persons with impaired respiratory function, airway diseases and conditions such

         as emphysema or chronic bronchitis, may incur further disability if excessive

         concentrations of particulate are inhaled.



     CHRONIC HEALTH EFFECTS

         Principal routes of exposure are by accidental skin and eye contact and

         inhalation of generated dusts. Exposure to phthalates over years leads to pain,

         numbness and spasms in the hands and feet. Many people have developed multiple

         disorders in the nervous system and the balancing system. Levels of sex hormones

         are reduced in women, leading to missed ovulations and miscarriages. They also

         reduce sperm counts and fertility in men. They mimic certain sex hormones and

         can damage the foetus. Phthalates are found in paints, inks and glues.



TOXICITY AND IRRITATION

TOXICITY                                                          IRRITATION

Oral (rat) LD50: 10400 mg/kg                                      Eye (rabbit): 500 mg/24h - Mild

Intraperitoneal (mouse) LD50: 4200 mg/kg





           Section 12 - ECOLOGICAL INFORMATION



           "log Pow (Verschueren 1983):" 1.66



           log Kow: 1.66

           Toxicity Fish:       LC50(96)145-295mg/L

           Toxicity invertebrate:        LC50(48)120mg/L

           Bioaccumulation: not sig

           Effects on algae and plankton: EC50(96)105-122mg/L

           Degradation Biological: some

           processes Abiotic: nohydrl&photl,oxid not sig,RxnOH*





           Section 13 - DISPOSAL CONSIDERATIONS



           � Recycle wherever possible or consult manufacturer for recycling options.

           � Consult State Land Waste Authority for disposal.

           � Bury or incinerate residue at an approved site.

           � Recycle containers if possible, or dispose of in an authorised landfill.





           Section 14 - TRANSPORTATION INFORMATION





HAZCHEM

           None





           NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS:UN,IATA,IMDG





           Section 15 - REGULATORY INFORMATION





POISONS SCHEDULE

         None



REGULATIONS



           isophthalic acid (CAS: 121-91-5) is found on the following regulatory lists;

                                       ISOPHTHALIC ACID

Chemwatch Material Safety Data Sheet (REVIEW)

Issue Date: 12-May-2005                                                                 CHEMWATCH 21970-1

A317TC                                                                                  CD 2006/2 Page 9 of 9

                                                                      Section 15 - REGULATORY INFORMATION



           Australia High Volume Industrial Chemical List (HVICL)

           Australia Inventory of Chemical Substances (AICS)

           International Council of Chemical Associations (ICCA) - High Production Volume

           List

           OECD Representative List of High Production Volume (HPV) Chemicals





           Section 16 - OTHER INFORMATION





Denmark Advisory list for selfclassification of dangerous substances

         Substance                                           CAS              Suggested codes

         isophthalic acid                                    121-91-5         R43



           This document is copyright. Apart from any fair dealing for the purposes of

           private study, research, review or criticism, as permitted under the Copyright

           Act, no part may be reproduced by any process without written permission from

           CHEMWATCH. TEL (+61 3) 9572 4700.



           Issue Date: 12-May-2005

           Print Date: 28-Jun-2006