METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 8-Jan-2006 CHEMWATCH 1247
NC317TCP CD 2006/4 Page 1 of 16
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
METHYL METHACRYLATE
SYNONYMS
C5-H8-O2, "MMA monomer inhibited", "2-methyl acrylic acid methyl ester", "methyl alpha
methacrylate", "methyl, 2-methyl-2-propenoate", "2-methyl-2-propenoic acid methyl ester"
, "2-propenoic acid, 2-methyl methyl ester"
PROPER SHIPPING NAME
METHYL METHACRYLATE MONOMER, STABILIZED
PRODUCT USE
Large volume industrial use in acrylic (methacrylate) plastics. Component as reactive
monomer of acrylic copolymer resins and latex emulsions used in paints, adhesives, paper
coatings, inks. Must contain stabilising inhibitor for safe transport and storage.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Quantum Industrial Park
Dandenong South VIC 3175
Australia
Telephone: 1300 782 688
Emergency Tel: 1300 131 001
Fax: 1300 782 699
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 8-Jan-2006 CHEMWATCH 1247
NC317TCP CD 2006/4 Page 2 of 16
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. DANGEROUS GOODS. According to the Criteria of NOHSC,
and the ADG Code.
POISONS SCHEDULE
None
RISK SAFETY
Highly flammable. Keep away from sources of ignition. No smoking.
May form explosive peroxides. Do not breathe gas/fumes/vapour/spray.
Irritating to eyes, respiratory system and skin. Wear eye/face protection.
May cause SENSITISATION by skin contact. Use only in well ventilated areas.
Inhalation and/or ingestion may produce health Keep container in a well ventilated place.
damage*.
Cumulative effects may result following Do not empty into drains.
exposure*.
Limited evidence of a carcinogenic effect*. To clean the floor and all objects contaminated
by this material, use water and detergent.
Possible respiratory sensitiser*. Keep container tightly closed.
* (limited evidence). Take off immediately all contaminated clothing.
In case of contact with eyes, rinse with plenty
of water and contact Doctor or Poisons
Information Centre.
If swallowed, IMMEDIATELY contact Doctor or
Poisons Information Centre. (show this container
or label).
This material and its container must be disposed
of as hazardous waste.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
methyl methacrylate 80-62-6 >99.5
inhibitor, stabiliser, as either of
hydroquinone 123-31-9 0.0020 max
or MEHQ, monomethyl ether of hydroquinone, as
4- methoxyphenol (MEHQ) 150-76-5 0.0020 max
Section 4 - FIRST AID MEASURES
SWALLOWED
路 Immediately give a glass of water.
路 First aid is not generally required. If in doubt, contact a Poisons Information Centre
or a doctor.
EYE
If this product comes in contact with the eyes:
METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 8-Jan-2006 CHEMWATCH 1247
NC317TCP CD 2006/4 Page 3 of 16
Section 4 - FIRST AID MEASURES
路 Wash out immediately with fresh running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 If pain persists or recurs seek medical attention.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
SKIN
If skin contact occurs:
路 Immediately remove all contaminated clothing, including footwear
路 Flush skin and hair with running water (and soap if available).
路 Seek medical attention in event of irritation.
INHALED
路 If fumes or combustion products are inhaled remove from contaminated area.
路 Lay patient down. Keep warm and rested.
路 Prostheses such as false teeth, which may block airway, should be removed, where
possible, prior to initiating first aid procedures.
路 Apply artificial respiration if not breathing, preferably with a demand valve
resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary.
路 Transport to hospital, or doctor, without delay.
NOTES TO PHYSICIAN
Treat symptomatically.
Significant effects developing over a work-shift are not detected by
symptomatology, blood pressure, respiratory function testing, haemoglobin
and white cell count, urinalysis and blood chemistry. Effects may occur in
high concentration exposure groups with regard to serum glucose and blood
urea, nitrogen, cholesterol, albumin and total bilirubin values. Possible
alterations occur in skin and nervous system symptomatology, urinalysis
findings and serum triglycerides. Diagnostic signs taken as indicative of
methyl methacrylate-induced local neurotoxicity include sensory nerve
distal conduction velocities. These deficits appear to result from
diffusion of the substance into neurons, lysis of membrane lipids and
demyelination.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 Foam.
路 Dry chemical powder.
路 BCF (where regulations permit).
路 Carbon dioxide.
路 Water spray or fog - Large fires only.
FIRE FIGHTING
路 Alert Fire Brigade and tell them location and nature of hazard.
路 May be violently or explosively reactive.
路 Wear breathing apparatus plus protective gloves.
路 Prevent, by any means available, spillage from entering drains or water course.
路 Consider evacuation (or protect in place).
路 Fight fire from a safe distance, with adequate cover.
路 If safe, switch off electrical equipment until vapour fire hazard removed.
路 Use water delivered as a fine spray to control the fire and cool adjacent area.
路 Avoid spraying water onto liquid pools.
路 Do not approach containers suspected to be hot.
路 Cool fire exposed containers with water spray from a protected location.
路 If safe to do so, remove containers from path of fire.
METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 8-Jan-2006 CHEMWATCH 1247
NC317TCP CD 2006/4 Page 4 of 16
Section 5 - FIRE FIGHTING MEASURES
FIRE/EXPLOSION HAZARD
路 Liquid and vapour are highly flammable.
路 Severe fire hazard when exposed to heat, flame and/or oxidisers.
路 Vapour may travel a considerable distance to source of ignition.
路 Heating may cause expansion or decomposition leading to violent rupture of containers.
路 On combustion, may emit toxic fumes of carbon monoxide (CO).
Combustion products include: carbon dioxide (CO2), other pyrolysis products typical of
burning organic material.
May emit clouds of acrid smoke, nitrogen oxides (NOx).
FIRE INCOMPATIBILITY
Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine
bleaches, pool chlorine etc. as ignition may result.
HAZCHEM: 3[Y]E
Personal Protective Equipment
Breathing apparatus.
Gas tight chemical resistant suit.
Limit exposure duration to 1 BA set30 mins.
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
路 Remove all ignition sources.
路 Clean up all spills immediately.
路 Avoid breathing vapours and contact with skin and eyes.
路 Control personal contact by using protective equipment.
路 Contain and absorb small quantities with vermiculite or other absorbent material.
路 Wipe up.
路 Collect residues in a flammable waste container.
MAJOR SPILLS
路 Clear area of personnel and move upwind.
路 Alert Fire Brigade and tell them location and nature of hazard.
路 May be violently or explosively reactive.
路 Wear breathing apparatus plus protective gloves.
路 Prevent, by any means available, spillage from entering drains or water course.
路 Consider evacuation (or protect in place).
路 No smoking, naked lights or ignition sources.
路 Increase ventilation.
路 Stop leak if safe to do so.
路 Water spray or fog may be used to disperse /absorb vapour.
路 Contain spill with sand, earth or vermiculite.
路 Use only spark-free shovels and explosion proof equipment.
路 Collect recoverable product into labelled containers for recycling.
路 Absorb remaining product with sand, earth or vermiculite.
路 Collect solid residues and seal in labelled drums for disposal.
路 Wash area and prevent runoff into drains.
路 If contamination of drains or waterways occurs, advise emergency services.
PROTECTIVE ACTIONS FOR SPILL
WARNING
METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 8-Jan-2006 CHEMWATCH 1247
NC317TCP CD 2006/4 Page 5 of 16
Section 6 - ACCIDENTAL RELEASE MEASURES
PROTECTIVE ACTION ZONE
half
evacuation
downwind
direction
distance
down wind distance
wind isolation
distance
direction
half
evacuation downwind
INITIAL direction distance
ISOLATION
ZONE
From IERG (Canada/Australia)
Isolation Distance 50 metres
Downwind Protection Distance 300 metres
IERG Number 18P
FOOTNOTES
1 PROTECTIVE ACTION ZONE is defined as the area in which people are at risk of harmful exposure. This zone
assumes that random changes in wind direction confines the vapour plume to an area within 30 degrees on
either side of the predominant wind direction, resulting in a crosswind protective action distance equal
to the downwind protective action distance.
2 PROTECTIVE ACTIONS should be initiated to the extent possible, beginning with those closest to the spill
and working away from the site in the downwind direction. Within the protective action zone a level of
vapour concentration may exist resulting in nearly all unprotected persons becoming incapacitated and
unable to take protective action and/or incurring serious or irreversible health effects.
3 INITIAL ISOLATION ZONE is determined as an area, including upwind of the incident, within which a high
probability of localised wind reversal may expose nearly all persons without appropriate protection to
life-threatening concentrations of the material.
4 SMALL SPILLS involve a leaking package of 200 litres (55 US gallons) or less, such as a drum (jerrican or
box with inner containers). Larger packages leaking less than 200 litres and compressed gas leaking from
a small cylinder are also considered "small spills".
LARGE SPILLS involve many small leaking packages or a leaking package of greater than 200 litres, such as
a cargo tank, portable tank or a "one-tonne" compressed gas cylinder.
5 Guide 129P is taken from the US DOT emergency response guide book.
6 IERG information is derived from CANUTEC - Transport Canada.
EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)
The maximum airborne concentration below which it is believed that nearly all individuals could be exposed
for up to one hour WITHOUT experiencing or developing
life-threatening health effects is:
methyl methacrylate 1000 ppm
irreversible or other serious effects or symptoms which could impair an individual's ability to take
protective action is:
methyl methacrylate 100 ppm
other than mild, transient adverse effects without perceiving a clearly defined odour is:
methyl methacrylate 100 ppm
The threshold concentration below which most people will experience no appreciable risk of health effects:
methyl methacrylate 100 ppm
American Industrial Hygiene Association (AIHA)
Ingredients considered according to the following cutoffs
Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0%
R50 >= 0.25% Corrosive (C) >= 5.0%
METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 8-Jan-2006 CHEMWATCH 1247
NC317TCP CD 2006/4 Page 6 of 16
Section 6 - ACCIDENTAL RELEASE MEASURES
R51 >= 2.5%
else >= 10%
where percentage is percentage of ingredient found in the mixture
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
___________________________________________
+ X X X X +
___________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
路 Most acrylic monomers have low viscosity therefore pouring, material transfer and
processing of these materials do not necessitate heating.
路 Viscous monomers may require heating to facilitate handling. To facilitate product
transfer from original containers, product must be heated to no more than 60 deg. C. (140
F.), for not more than 24 hours.
路 Do NOT use localised heat sources such as band heaters to heat/ melt product.
路 Do NOT use steam.
路 Hot boxes or hot rooms are recommended for heating/ melting material. The hot box or
hot room should be set a maximum temperature of 60 deg. C. (140 F.).
路 Do NOT overheat - this may compromise product quality and /or result in an uncontrolled
hazardous polymerisation.
路 If product freezes, heat as indicated above and mix gently to redistribute the
inhibitor. Product should be consumed in its entirety after heating/ melting; avoid
multiple "reheats" which may affect product quality or result in product degradation.
路 Product should be packaged with inhibitor(s). Unless inhibited, product may polymerise,
raising temperature and pressure, possibly rupturing container. Check inhibitor level
periodically, adding to bulk material if needed. In addition, the product's inhibitor(s)
require the presence of dissolved oxygen. Maintain, at a minimum, the original headspace
in the product container and do NOT blanket or mix with oxygen-free gas as it renders the
inhibitor ineffective. Ensure air space (oxygen) is present during product heating /
melting.
路 Store product indoors at temperatures greater than the product's freeing point (or
greater than 0 deg. C. (32 F).) if no freezing point available and below 38 deg. C (100
F.).
路 Avoid prolonged storage (longer than shelf-life) storage temperatures above 38 deg. C
(100 F.).
路 Store in tightly closed containers in a properly vented storage area away from heat,
sparks, open flame, strong oxidisers, radiation and other initiators.
路 Prevent contamination by foreign materials.
路 Prevent moisture contact.
路 Use only non-sparking tools and limit storage time. Unless specified elsewhere, shelf
-life is 6 months from receipt.
The substance is a peroxidisable vinyl monomer that may exothermically polymerise as a
result of decomposition of accumulated peroxides; that is, the peroxides initiate very
energetic polymerisation of the bulk monomer
Purchases of peroxidisable chemicals should be restricted to ensure that the chemical is
used completely before it can become peroxidised.
路 A responsible person should maintain an inventory of peroxidisable chemicals or
METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 8-Jan-2006 CHEMWATCH 1247
NC317TCP CD 2006/4 Page 7 of 16
Section 7 - HANDLING AND STORAGE
annotate the general chemical inventory to indicate which chemicals are subject to
peroxidation. An expiration date should be determined. The chemical should either be
treated to remove peroxides or disposed of before this date.
路 The person or laboratory receiving the chemical should record a receipt date on the
bottle. The individual opening the container should add an opening date.
路 Unopened containers received from the supplier should be safe to store for 18 months.
路 Opened containers of uninhibited material should not be stored for more than 24 hours.
路 Opened containers of inhibited material should not be stored for more than 12 months;
they should not be stored under an inert atmosphere.
路 Avoid all personal contact, including inhalation.
路 Wear protective clothing when risk of exposure occurs.
路 Use in a well-ventilated area.
路 Prevent concentration in hollows and sumps.
路 DO NOT enter confined spaces until atmosphere has been checked.
路 Avoid smoking, naked lights, heat or ignition sources.
路 When handling, DO NOT eat, drink or smoke.
路 Vapour may ignite on pumping or pouring due to static electricity.
路 DO NOT use plastic buckets.
路 Earth and secure metal containers when dispensing or pouring product.
路 Use spark-free tools when handling.
路 Avoid contact with incompatible materials.
路 Keep containers securely sealed.
路 Avoid physical damage to containers.
路 Always wash hands with soap and water after handling.
路 Work clothes should be laundered separately.
路 Use good occupational work practice.
路 Observe manufacturer's storing and handling recommendations.
路 Atmosphere should be regularly checked against established exposure standards to
ensure safe working conditions.
DO NOT allow clothing wet with material to stay in contact with skin.
SUITABLE CONTAINER
Packing as supplied by manufacturer. Plastic containers may only be used if approved for
flammable liquid. Check that containers are clearly labelled and free from leaks.
路 For low viscosity materials (i) : Drums and jerry cans must be of the non-removable
head type. (ii) : Where a can is to be used as an inner package, the can must have a
screwed enclosure.
路 For materials with a viscosity of at least 2680 cSt. (23 deg. C)
路 For manufactured product having a viscosity of at least 250 cSt. (23 deg. C)
路 Manufactured product that requires stirring before use and having a viscosity of at
least 20 cSt (25 deg. C)
(i) : Removable head packaging;
(ii) : Cans with friction closures and
(iii) : low pressure tubes and cartridges may be used.
路 Where combination packages are used, and the inner packages are of glass, there must be
sufficient inert cushioning material in contact with inner and outer packages
路 In addition, where inner packagings are glass and contain liquids of packing group I
there must be sufficient inert absorbent to absorb any spillage, unless the outer
packaging is a close fitting moulded plastic box and the substances are not incompatible
with the plastic.
STORAGE INCOMPATIBILITY
Contamination with polymerisation catalysts - peroxides, persulfates, oxidising agents -
also strong acids, strong alkalies, will cause polymerisation with exotherm - generation
of heat.
Polymerisation of large quantities may be violent - even explosive.
Avoid reaction with oxidising agents.
Segregate from, strong acids, strong alkalis, Flammable solid., amines.
STORAGE REQUIREMENTS
路 Stable under controlled storage conditions provided material contains adequate
METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 8-Jan-2006 CHEMWATCH 1247
NC317TCP CD 2006/4 Page 8 of 16
Section 7 - HANDLING AND STORAGE
stabiliser / polymerisation inhibitor.
路 Bulk storages may have special storage requirements.
路 Storage requires stabilising inhibitor content and dissolved oxygen content to be
monitored. Refer to manufacturer's recommended levels.
路 DO NOT overfill containers so as to maintain free head space above product.
路 Blanketing or sparging with nitrogen or oxygen free gas will deactivate stabiliser.
Easily peroxidisable. Products formed as a result of peroxidation are not only safety
hazards but may chemically alter the chemical behavior of the parent compound.
Should have a warning label affixed bearing the date of receipt in the laboratory and the
date on which the container label is first opened, or laboratory synthesised materials
are the responsibility of the individual chemist.
WARNING: This product may form peroxides which themselves are not Quantities of
uninhibited monomers exceeding 500 ml should not be stored for more than 24 hours.
The oxidation of iodide to iodine or the conversion of colourless ferrothiocyanate to red
ferrithiocyanate by peroxides are simple and convenient tests for most peroxides.
Before distilling or evaporating a suitable polymerisation inhibitor should be added.
Leave at least 10% bottoms. Use a shield when evaporating or distilling mixtures which
may contain peroxidisable compounds. Store away from heat and light. Particular attention
should be paid to the adequacy of the closure on storage containers. Peroxides may be
removed by; (1) passing the material over a column of ordinary activated alumina (care
should be taken in disposal of the activated alumina); (2) shaking with a concentrated
solution of ferrous salt (provided the carrier solvent is water-insoluble); (3) agitation
with an approximately equimolar mixture of ferrous sulfate and sodium bisulfate; (4)
commercial quantities may be treated with a 5% solution of aqueous sodium carbonate.
Jackson et al: Control of Peroxizable Compounds; Safety in the Chemical
Laboratory, Journal of Chemical Education; Vol 47, 1970, pp A175-A188
When solvents have been freed from peroxides by percolation through a column of activated
alumina, the adsorbed peroxides must promptly be desorbed by treatment with polar
solvents, methanol or water, which must in turn be discarded safely.***.
路 Store in original containers in approved flame-proof area.
路 No smoking, naked lights, heat or ignition sources.
路 DO NOT store in pits, depressions, basements or areas where vapours may be trapped.
路 Keep containers securely sealed.
路 Store away from incompatible materials in a cool, dry well ventilated area.
路 Protect containers against physical damage and check regularly for leaks.
路 Observe manufacturer's storing and handling recommendations.
WARNING: Gradual decomposition in strong, sealed containers may lead to a
large pressure build-up and subsequent explosion.
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA TWA STEL STEL Peak Peak TWA
ppm mg/m鲁 ppm mg/m鲁 ppm mg/m鲁 F/CC
_________________ __________________ ______ ______ ______ ______ ______ ______ _____
Australia Exposure methyl 50 208 100 416
Standards methacrylate
(Methyl
methacrylate)
Australia Exposure hydroquinone 2
Standards (Hydroquinone)
Australia Exposure 4- methoxyphenol 5
Standards (MEHQ) (4-
Methoxyphenol)
METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 8-Jan-2006 CHEMWATCH 1247
NC317TCP CD 2006/4 Page 9 of 16
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EMERGENCY EXPOSURE LIMITS
Material Revised IDLH Value (mg/m3) Revised IDLH Value (ppm)
methyl methacrylate 1, 000
hydroquinone 50
MATERIAL DATA
Odour Threshold Value: 0.049 ppm (detection), 0.34 ppm (recognition)
NOTE: Detector tubes measuring in excess of 50 ppm, are available.
Concentrations as low as 125 ppm have produced irritation of the mucous
membranes of exposed workers. The recommended TLV-TWA is thought to be
sufficiently low to protect against discomfort from irritation and acute
systemic intoxication.
INGREDIENT DATA
HYDROQUINONE:
The recommended TLV-TWA takes into account the toxicology of hydroquinone
and experience of industrial exposures to benzenediols. Exposure at or
below the limit is thought to minimise the risk to workers of eye injury,
dermatitis and central nervous system effects. A short-term duration
exposure value has not been recommended, because no quantitative data as
to the levels of hydroquinone which produce eye irritation or more serious
corneal changes has been identified.
4-METHOXYPHENOL (MEHQ):
MEHQ has caused ocular toxicity in animals and skin depigmentation in
rodents and workers. The recommendation for the TLV-TWA arises from
documented eye and skin toxicities and by analogy with hydroquinone.
PERSONAL PROTECTION
EYE
路 Safety glasses with side shields.
路 Chemical goggles.
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
Wear chemical protective gloves, eg. PVC.
Wear safety footwear or safety gumboots, eg. Rubber.
NOTE: The material may produce skin sensitisation in predisposed individuals. Care must
be taken, when removing gloves and other protective equipment, to avoid all possible skin
contact.
METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 8-Jan-2006 CHEMWATCH 1247
NC317TCP CD 2006/4 Page 10 of 16
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
OTHER
路 Overalls.
路 PVC Apron.
路 PVC protective suit may be required if exposure severe.
路 Eyewash unit.
路 Ensure there is ready access to a safety shower.
GLOVE SELECTION INDEX
Glove selection is based on a modified presentation of the:
" Forsberg Clothing Performance Index" .
The effect(s) of the following substance(s) are taken into account in the
computer- generated selection: methyl methacrylate
Protective Material CPI *.
__________________________________________
PE/EVAL/PE A
PVA A
TEFLON A
BUTYL C
__________________________________________
* CPI - Chemwatch Performance Index
A: Best Selection
B: Satisfactory; may degrade after 4 hours continuous immersion
C: Poor to Dangerous Choice for other than short term immersion
NOTE: As a series of factors will influence the actual performance of the glove,
a final selection must be based on detailed observation. -
* Where the glove is to be used on a short term, casual or infrequent basis,
factors such as "feel" or convenience (e.g. disposability), may dictate a choice
of gloves which might otherwise be unsuitable following long-term or frequent use.
A qualified practitioner should be consulted.
RESPIRATOR
Selection of the Class and Type of respirator will depend upon the level of breathing
zone contaminant and the chemical nature of the contaminant. Protection Factors (defined
as the ratio of contaminant outside and inside the mask) may also be important.
Breathing Zone Level Maximum Protection Half- face Respirator Full- Face Respirator
ppm (volume) Factor
1000 10 A- AUS -
1000 50 - A- AUS
5000 50 Airline * -
5000 100 - A- 2
10000 100 - A- 3
100+ Airline**
* - Continuous Flow ** - Continuous-flow or positive pressure demand.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
For flammable liquids and flammable gases, local exhaust ventilation or a process
enclosure ventilation system may be required. Ventilation equipment should be explosion
-resistant.
Air contaminants generated in the workplace possess varying "escape" velocities which, in
turn, determine the "capture velocities" of fresh circulating air required to effectively
remove the contaminant.
Type of Contaminant: Air Speed:
METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 8-Jan-2006 CHEMWATCH 1247
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Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
solvent, vapours, degreasing etc., evaporating 0.25- 0.5 m/s (50- 100 f/min.)
from tank (in still air).
aerosols, fumes from pouring operations, 0.5- 1 m/s (100- 200 f/min.)
intermittent container filling, low speed
conveyer transfers, welding, spray drift,
plating acid fumes, pickling (released at low
velocity into zone of active generation)
direct spray, spray painting in shallow 1- 2.5 m/s (200- 500 f/min.)
booths, drum filling, conveyer loading,
crusher dusts, gas discharge (active
generation into zone of rapid air motion)
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only.
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood- local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
source. The air velocity at the extraction fan, for example, should be a minimum of 1-2
m/s (200-400 f/min.) for extraction of solvents generated in a tank 2 meters distant from
the extraction point. Other mechanical considerations, producing performance deficits
within the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or used.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Clear highly flammable liquid; floats on water. Highly reactive monomer. Sweet, sharp
fruity odour.
PHYSICAL PROPERTIES
Liquid.
Molecular Weight: 100.11 Boiling Range (掳C): 100- 101
Melting Range (掳C): - 48 Specific Gravity (water=1): 0.936- 0.94
Solubility in water (g/L): 1.5% pH (as supplied): Not applicable
pH (1% solution): Not applicable Vapour Pressure (kPa): 4.6 @ 20 deg.C
Volatile Component (%vol): 100 Evaporation Rate: > 1.0 BuAc=1
Relative Vapour Density (air=1): 3.45 Flash Point (掳C): 13.8
Lower Explosive Limit (%): 2.1 Upper Explosive Limit (%): 12.5
Autoignition Temp (掳C): 421- 435 Decomposition Temp (掳C): Not Available
State: Liquid Viscosity: Not Available
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
路 Presence of incompatible materials.
路 Product is considered stable.
路 Hazardous polymerisation will not occur.
METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 8-Jan-2006 CHEMWATCH 1247
NC317TCP CD 2006/4 Page 12 of 16
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
The material is not thought to produce adverse health effects following ingestion (as
classified by EC Directives using animal models). Nevertheless, adverse systemic effects
have been produced following exposure of animals by at least one other route and good
hygiene practice requires that exposure be kept to a minimum.
Central nervous system (CNS) depression may include general discomfort, symptoms of
giddiness, headache, dizziness, nausea, anaesthetic effects, slowed reaction time,
slurred speech and may progress to unconsciousness. Serious poisonings may result in
respiratory depression and may be fatal.
EYE
This material can cause eye irritation and damage in some persons.
SKIN
This material can cause inflammation of the skin on
contact in some persons.
The material may accentuate any pre-existing dermatitis condition.
Skin contact is not thought to produce harmful health effects (as classified under EC
Directives using animal models). Systemic harm, however, has been identified following
exposure of animals by at least one other route and the material may still produce health
damage following entry through wounds, lesions or abrasions. Good hygiene practice
requires that exposure be kept to a minimum and that suitable gloves be used in an
occupational setting.
Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may
produce systemic injury with harmful effects. Examine the skin prior to the use of the
material and ensure that any external damage is suitably protected.
INHALED
Inhalation of aerosols (mists, fumes), generated by the material during the course of
normal handling, may be harmful.
There is some evidence to suggest that this material
can cause, if inhaled once, irreversible damage
of organs.
The material can cause respiratory irritation in some persons. The body's response to
such irritation can cause further lung damage.
If exposure to highly concentrated vapour atmosphere is prolonged this may lead to
narcosis, unconsciousness, even coma and unless resuscitated - death.
Acute effects from inhalation of high vapour concentrations may be chest and nasal
irritation with coughing, sneezing, headache and even nausea.
At sufficiently high doses the material may be hepatotoxic
(i.e. poisonous to the liver).
At sufficiently high doses the material may be neurotoxic (i.e. poisonous to the nervous
system).
CHRONIC HEALTH EFFECTS
Substance accumulation, in the human body, may occur and may cause some concern following
repeated or long-term occupational exposure.
Asthma-like symptoms may continue for months or even years after exposure to the material
ceases. This may be due to a non-allergenic condition known as reactive airways
dysfunction syndrome (RADS) which can occur following exposure to high levels of highly
irritating compound. Key criteria for the diagnosis of RADS include the absence of
preceding respiratory disease, in a non-atopic individual, with abrupt onset of
persistent asthma-like symptoms within minutes to hours of a documented exposure to the
irritant. A reversible airflow pattern, on spirometry, with the presence of moderate to
severe bronchial hyperreactivity on methacholine challenge testing and the lack of
METHYL METHACRYLATE
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Section 11 - TOXICOLOGICAL INFORMATION
minimal lymphocytic inflammation, without eosinophilia, have also been included in the
criteria for diagnosis of RADS. RADS (or asthma) following an irritating inhalation is an
infrequent disorder with rates related to the concentration of and duration of exposure
to the irritating substance. Industrial bronchitis, on the other hand, is a disorder that
occurs as result of exposure due to high concentrations of irritating substance (often
particulate in nature) and is completely reversible after exposure ceases. The disorder
is characterised by dyspnea, cough and mucous production.
There has been some concern that this material can cause cancer or mutations but there is
not enough data to make an assessment.
There is some evidence that inhaling this product is more likely to cause a sensitisation
reaction in some persons compared to the general population.
Skin contact with the material is more likely to cause a sensitisation reaction in some
persons compared to the general population.
Sensitisation may give severe responses to very low levels of exposure, i.e.
hypersensitivity. Sensitised persons should not be allowed to work in situations where
exposure may occur.
Sensitisation may result in allergic dermatitis responses including rash, itching, hives
or swelling of extremities.
TOXICITY AND IRRITATION
TOXICITY IRRITATION
Oral (rat) LD50: 7872 mg/kg Skin (rabbit): 10000 mg/kg (open)
Inhalation (human) TCLo: 125 ppm Eye (rabbit): 150 mg
Dermal (rabbit) LD50: >5000 mg/kg
Inhalation (rat) LC50: 3750 ppm *
Dermal (rabbit) LD50: 35500 mg/kg *
Inhalation (human) TCLo: 60 mg/m鲁(15 ppm) [*
Manuf. Rohm & Haas]
The substance is classified by IARC as Group 3:
NOT classifiable as to its carcinogenicity to humans.
Evidence of carcinogenicity may be inadequate or limited in animal testing.
Based on the available oncogenicity data and without a better understanding of the
carcinogenic mechanism the Health and Environmental Review Division (HERD), Office of
Toxic Substances (OTS), of the US EPA previously concluded that all chemicals that
contain the acrylate or methacrylate moiety (CH2=CHCOO or CH2=C(CH3)COO) should be
considered to be a carcinogenic hazard unless shown otherwise by adequate testing.
This position has now been revised and acrylates and methacrylates are no longer de facto
carcinogens.
HYDROQUINONE:
TOXICITY IRRITATION
Oral (human) LDLo: 29 mg/kg Skin (human): 2% - Mild
Oral (human) TDLo: 170 mg/kg Skin (human): 5% - SEVERE
Oral (rat) LD50: 320 mg/kg
The material may cause severe skin irritation after prolonged or repeated exposure and
may produce on contact skin redness, swelling, the production of vesicles, scaling and
thickening of the skin. Repeated exposures may produce severe ulceration.
Contact allergies quickly manifest themselves as contact eczema, more rarely as urticaria
or Quincke's oedema. The pathogenesis of contact eczema involves a cell-mediated (T
lymphocytes) immune reaction of the delayed type. Other allergic skin reactions, e.g.
contact urticaria, involve antibody-mediated immune reactions. The significance of the
contact allergen is not simply determined by its sensitisation potential: the
distribution of the substance and the opportunities for contact with it are equally
important. A weakly sensitising substance which is widely distributed can be a more
important allergen than one with stronger sensitising potential with which few
individuals come into contact. From a clinical point of view, substances are noteworthy
if they produce an allergic test reaction in more than 1% of the persons tested.
The substance is classified by IARC as Group 3:
METHYL METHACRYLATE
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Section 11 - TOXICOLOGICAL INFORMATION
NOT classifiable as to its carcinogenicity to humans.
Evidence of carcinogenicity may be inadequate or limited in animal testing.
4-METHOXYPHENOL (MEHQ):
TOXICITY IRRITATION
Oral (rat) LD50: 1600 mg/kg Skin (rabbit): 6000 mg/12d- I Mild
MATERIAL CARCINOGEN REPROTOXIN SENSITISER SKIN
________________________ ____________________ ________________ ________________ ___________
methyl methacrylate IARC:3 ILOEl AUOEL
hydroquinone IARC:3
CARCINOGEN
IARC: International Agency for Research on Cancer (IARC) Carcinogens: methyl
methacrylate Category: 3
REPROTOXIN
ILOEl: ILO Chemicals in the electronics industry that have toxic effects on
reproduction: methyl methacrylate
SENSITISER
AUOEL: Australia Exposure Standards - Sensitisers: methyl methacrylate
CARCINOGEN
IARC: International Agency for Research on Cancer (IARC) Carcinogens: hydroquinone
Category: 3
Section 12 - ECOLOGICAL INFORMATION
DO NOT discharge into sewer or waterways.
Koc: 87
Half-life (hr) air: 2.7-3
Half-life (hr) H2O surface water: 6.3-336
Henry's atm m鲁 /mol: 3.24E-04
BOD 5 if unstated: 0.14
Log BCF: 0.55
Toxicity Fish: LC50(96)0.089mg/L
Refer to data for ingredients, which follows:
HYDROQUINONE:
Environmental toxicity is a function of the n-octanol/ water partition coefficient (log
Pow, log Kow). Phenols with log Pow >7.4 are expected to exhibit low toxicity to aquatic
organisms. However the toxicity of phenols with a lower log Pow is variable, ranging from
low toxicity (LC50 values >100 mg/l) to highly toxic (LC50 values <1 mg/l) dependent on
log Pow, molecular weight and substitutions on the aromatic ring. Dinitrophenols are more
toxic than predicted from QSAR estimates. Hazard information for these groups is not
generally available.
Do NOT allow product to come in contact with surface waters or to intertidal areas below
the mean high water mark. Do not contaminate water when cleaning equipment or disposing
of equipment wash-waters.
Wastes resulting from use of the product must be disposed of on site or at approved waste
sites.
DO NOT discharge into sewer or waterways.
The material is classified as an ecotoxin* because the Fish LC50 (96 hours) is less than
or equal to 0.1 mg/l
* Classification of Substances as Ecotoxic (Dangerous to the Environment)
Appendix 8, Table 1
Compiler's Guide for the Preparation of International Chemical Safety Cards: 1993
Commission of the European Communities.
log Kow: 0.5-0.59
Koc: 9-50
BOD 5: 0.478-1,25-37%
COD: 1.83,90%
METHYL METHACRYLATE
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Section 12 - ECOLOGICAL INFORMATION
ThOD: 1.89
BCF: 40-65
Toxicity Fish: tox(24) 0.86-25mg/L
Toxicity invertebrate: TLm(96) insct 0.316mg/L
l
4-METHOXYPHENOL (MEHQ):
Fish LC50 (96hr.) (mg/l): 200 (48hr)
log Pow (Verschueren 1983): 1.34
nbsp;log#nbsp;Kow#nbsp;#nbsp;:#nbsp;1.34
Degradation Biological: by soil microflora 16 days
Section 13 - DISPOSAL CONSIDERATIONS
路 Recycle wherever possible.
路 Consult manufacturer for recycling options or consult local or regional waste
management authority for disposal if no suitable treatment or disposal facility can be
identified.
路 Dispose of by: Burial in a licenced land-fill or Incineration in a licenced apparatus
(after admixture with suitable combustible material)
路 Decontaminate empty containers. Observe all label safeguards until containers are
cleaned and destroyed.
路 Containers may still present a chemical hazard/ danger when empty.
路 Return to supplier for reuse/ recycling if possible.
Otherwise:
路 If container can not be cleaned sufficiently well to ensure that residuals do not
remain or if the container cannot be used to store the same product, then puncture
containers, to prevent re-use, and bury at an authorised landfill.
路 Where possible retain label warnings and MSDS and observe all notices pertaining to the
product.
Section 14 - TRANSPORTATION INFORMATION
Labels Required: FLAMMABLE LIQUID
HAZCHEM: 3[Y]E
UNDG:
Dangerous Goods 3 Subrisk: None
Class:
UN Number: 1247 Packing Group: II
Shipping Name:METHYL METHACRYLATE MONOMER, STABILIZED
Air Transport IATA:
ICAO/IATA Class: 3 ICAO/IATA Subrisk: None
UN/ID Number: 1247 Packing Group: II
ERG Code: 3L
Shipping Name: Methyl methacrylate monomer, stabilized
Maritime Transport IMDG:
IMDG Class: 3 IMDG Subrisk: None
UN Number: 1247 Packing Group: II
METHYL METHACRYLATE
Chemwatch Material Safety Data Sheet (REVIEW)
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Section 14 - TRANSPORTATION INFORMATION
EMS Number: F- E, S- D
Shipping Name: METHYL METHACRYLATE MONOMER, STABILIZED
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: None
REGULATIONS
methyl methacrylate (CAS: 80-62-6) is found on the following regulatory lists;
Australia Dangerous Goods Code Draft 7th Edition - Goods too Dangerous to be
Transported
Australia Exposure Standards
Australia High Volume Industrial Chemical List (HVICL)
Australia Inventory of Chemical Substances (AICS)
Australia National Pollutant Inventory
IMO MARPOL 73/78 (Annex II) - List of Noxious Liquid Substances Carried in Bulk
International Agency for Research on Cancer (IARC) Carcinogens
International Air Transport Association (IATA) Dangerous Goods Regulations
OECD Representative List of High Production Volume (HPV) Chemicals
Section 16 - OTHER INFORMATION
REPRODUCTIVE HEALTH GUIDELINES
These exposure guidelines have been derived from a screening level of risk assessment and
should not be construed as unequivocally safe limits. ORGS represent an 8-hour time
-weighted average unless specified otherwise.
CR = Cancer Risk/10000; UF = Uncertainty factor:
TLV believed to be adequate to protect reproductive health:
LOD: Limit of detection
Toxic endpoints have also been identified as:
D = Developmental; R = Reproductive; TC = Transplacental carcinogen
Jankovic J., Drake F.: A Screening Method for Occupational Reproductive
American Industrial Hygiene Association Journal 57: 641-649 (1996).
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 8-Jan-2006
Print Date: 4-Jan-2007
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