MONO ETHYLENE GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 35231
NC317TCP Version No:2.0
CD 2007/3 Page 1 of 9
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
MONO ETHYLENE GLYCOL
SYNONYMS
C4-H8-O3, CH3COOCH2CH2OH, "acetic acid 2-hydroxyethyl ester", "acetic acid 2-hydroxyethyl
ester", "1, 2-ethanediol monoacetate", "1, 2-ethanediol monoacetate", "ethylene glycol
acetate", "glycol monoacetate", "2-hydroxy ethyl acetate", "2-hydroxy ethyl acetate",
"glycol monoacetin"
PRODUCT USE
Solvent for oils, nitrocellulose, cellulose acetate, camphor.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Dandenong South
Victoria 3175
Telephone: 03 8795 8000
Emergency Tel: 1300 131 001
Fax: 03 8795 8099
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to the Criteria of
NOHSC, and the ADG Code.
MONO ETHYLENE GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 35231
NC317TCP Version No:2.0
CD 2007/3 Page 2 of 9
Section 2 - HAZARDS IDENTIFICATION
POISONS SCHEDULE
None
RISK SAFETY
Irritating to eyes. Do not breathe gas/ fumes/ vapour/ spray.
Ingestion may produce health damage*. Wear eye/ face protection.
Cumulative effects may result following To clean the floor and all objects contaminated
exposure*. by this material use water.
May produce discomfort of the respiratory Take off immediately all contaminated clothing.
system*.
Vapours potentially cause drowsiness and In case of contact with eyes rinse with plenty
dizziness*. of water and contact Doctor or Poisons
Information Centre.
* (limited evidence). If swallowed IMMEDIATELY contact Doctor or
Poisons Information Centre (show this container
or label).
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
mono ethylene glycol 542-59-6 100
Section 4 - FIRST AID MEASURES
SWALLOWED
For advice, contact a Poisons Information Centre or a doctor.
路 If swallowed do NOT induce vomiting.
路 If vomiting occurs, lean patient forward or place on left side (head-down position, if
possible) to maintain open airway and prevent aspiration.
路 Observe the patient carefully.
路 Never give liquid to a person showing signs of being sleepy or with reduced awareness;
i.e. becoming unconscious
路 Give water to rinse out mouth, then provide liquid slowly and as much as casualty can
comfortably drink.
路 Seek medical advice.
EYE
If this product comes in contact with the eyes:
路 Immediately hold eyelids apart and flush the eye continuously with running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 Continue flushing until advised to stop by the Poisons Information Centre or a doctor,
or for at least 15 minutes.
路 Transport to hospital or doctor without delay.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
MONO ETHYLENE GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 35231
NC317TCP Version No:2.0
CD 2007/3 Page 3 of 9
Section 4 - FIRST AID MEASURES
SKIN
If skin contact occurs:
路 Immediately remove all contaminated clothing, including footwear.
路 Flush skin and hair with running water (and soap if available).
路 Seek medical attention in event of irritation.
INHALED
路 If fumes or combustion products are inhaled remove from contaminated area.
路 Lay patient down. Keep warm and rested.
路 Prostheses such as false teeth, which may block airway, should be removed, where
possible, prior to initiating first aid procedures.
路 Apply artificial respiration if not breathing, preferably with a demand valve
resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary.
路 Transport to hospital, or doctor, without delay.
NOTES TO PHYSICIAN
For acute or short term repeated exposures to ethylene glycol:
路 Early treatment of ingestion is important. Ensure emesis is satisfactory.
路 Test and correct for metabolic acidosis and hypocalcaemia.
路 Apply sustained diuresis when possible with hypertonic mannitol.
路 Evaluate renal status and begin haemodialysis if indicated. [I.L.O]
路 Rapid absorption is an indication that emesis or lavage is effective only in the first
few hours. Cathartics and charcoal are generally not effective.
路 Correct acidosis, fluid/electrolyte balance and respiratory depression in the usual
manner. Systemic acidosis (below 7.2) can be treated with intravenous sodium bicarbonate
solution.
路 Ethanol therapy prolongs the half-life of ethylene glycol and reduces the formation of
toxic metabolites.
路 Pyridoxine and thiamine are cofactors for ethylene glycol metabolism and should be
given (50 to 100 mg respectively) intramuscularly, four times per day for 2 days.
路 Magnesium is also a cofactor and should be replenished. The status of 4-methylpyrazole,
in the treatment regime, is still uncertain. For clearance of the material and its
metabolites, haemodialysis is much superior to peritoneal dialysis.
[Ellenhorn and Barceloux: Medical Toxicology]
It has been suggested that there is a need for establishing a new biological exposure
limit before a workshift that is clearly below 100 mmol ethoxy-acetic acids per mole
creatinine in morning urine of people occupationally exposed to ethylene glycol ethers.
This arises from the finding that an increase in urinary stones may be associated with
such exposures.
Laitinen J., et al: Occupational & Environmental Medicine 1996; 53, 595-600.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 Water spray or fog.
路 Foam.
路 Dry chemical powder.
路 BCF (where regulations permit).
路 Carbon dioxide.
FIRE FIGHTING
路 Use water delivered as a fine spray to control fire and cool adjacent area.
路 Do not approach containers suspected to be hot.
路 Cool fire exposed containers with water spray from a protected location.
路 If safe to do so, remove containers from path of fire.
路 Equipment should be thoroughly decontaminated after use.
MONO ETHYLENE GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 35231
NC317TCP Version No:2.0
CD 2007/3 Page 4 of 9
Section 5 - FIRE FIGHTING MEASURES
FIRE/EXPLOSION HAZARD
路 Combustible.
路 Slight fire hazard when exposed to heat or flame.
路 Heating may cause expansion or decomposition leading to violent rupture of containers.
路 On combustion, may emit toxic fumes of carbon monoxide (CO).
路 May emit acrid smoke.
路 Mists containing combustible materials may be explosive.
Other combustion products include: carbon dioxide (CO2).
FIRE INCOMPATIBILITY
Avoid contamination with strong oxidising agents as ignition may result.
HAZCHEM: None
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
路 Remove all ignition sources.
路 Clean up all spills immediately.
路 Avoid breathing vapours and contact with skin and eyes.
路 Control personal contact by using protective equipment.
路 Contain and absorb spill with sand, earth, inert material or vermiculite.
路 Wipe up.
路 Place in a suitable labelled container for waste disposal.
MAJOR SPILLS
路 Clear area of personnel and move upwind.
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Wear breathing apparatus plus protective gloves.
路 Prevent, by any means available, spillage from entering drains or water course.
路 Stop leak if safe to do so.
路 Contain spill with sand, earth or vermiculite.
路 Collect recoverable product into labelled containers for recycling.
路 Neutralise/decontaminate residue.
路 Collect solid residues and seal in labelled drums for disposal.
路 Wash area and prevent runoff into drains.
路 After clean up operations, decontaminate and launder all protective clothing and
equipment before storing and re-using.
路 If contamination of drains or waterways occurs, advise emergency services.
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
路 Avoid all personal contact, including inhalation.
路 Wear protective clothing when risk of exposure occurs.
路 Use in a well-ventilated area.
路 Prevent concentration in hollows and sumps.
路 DO NOT enter confined spaces until atmosphere has been checked.
路 Avoid smoking, naked lights or ignition sources.
路 Avoid contact with incompatible materials.
路 When handling, DO NOT eat, drink or smoke.
MONO ETHYLENE GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 35231
NC317TCP Version No:2.0
CD 2007/3 Page 5 of 9
Section 7 - HANDLING AND STORAGE
路 Keep containers securely sealed when not in use.
路 Avoid physical damage to containers.
路 Always wash hands with soap and water after handling.
路 Work clothes should be laundered separately.
路 Use good occupational work practice.
路 Observe manufacturer's storing and handling recommendations.
路 Atmosphere should be regularly checked against established exposure standards to
ensure safe working conditions.
SUITABLE CONTAINER
路 Metal can or drum
路 Packaging as recommended by manufacturer.
路 Check all containers are clearly labelled and free from leaks.
STORAGE INCOMPATIBILITY
Avoid reaction with oxidising agents, bases and strong reducing agents.
Avoid strong acids.
STORAGE REQUIREMENTS
路 Keep dry.
路 Store in original containers.
路 Keep containers securely sealed.
路 No smoking, naked lights or ignition sources.
路 Store in a cool, dry, well-ventilated area.
路 Store away from incompatible materials.
路 Protect containers against physical damage.
路 Check regularly for leaks.
路 Observe manufacturer's storing and handling recommendations.
_____________________________________________________
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
+ X + X 0 +
_____________________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
The following materials had no OELs on our records
鈥? ethylene glycol monoacetate: CAS:542- 59- 6
MATERIAL DATA
No exposure limits set by NOHSC or ACGIH.
OEL STEL (Russia): 30 mg/m3
PERSONAL PROTECTION
MONO ETHYLENE GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 35231
NC317TCP Version No:2.0
CD 2007/3 Page 6 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EYE
路 Safety glasses.
路 Safety glasses with side shields.
路 Chemical goggles.
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
路 Barrier cream with polyethylene gloves.
Butyl rubber gloves. or Neoprene gloves or PVC gloves.
Safety footwear.
DO NOT use this product to clean the skin.
OTHER
Overalls.
路 Impervious protective clothing.
路 Eyewash unit.
RESPIRATOR
Selection of the Class and Type of respirator will depend upon the level of breathing
zone contaminant and the chemical nature of the contaminant. Protection Factors (defined
as the ratio of contaminant outside and inside the mask) may also be important.
Breathing Zone Level Maximum Protection Half- face Respirator Full- Face Respirator
ppm (volume) Factor
1000 10 A- AUS -
1000 50 - A- AUS
5000 50 Airline * -
5000 100 - A- 2
10000 100 - A- 3
100+ Airline**
* - Continuous Flow ** - Continuous-flow or positive pressure demand.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
General exhaust is adequate under normal operating conditions. Local exhaust ventilation
may be required in specific circumstances. If risk of overexposure exists, wear approved
MONO ETHYLENE GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 35231
NC317TCP Version No:2.0
CD 2007/3 Page 7 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
respirator. Correct fit is essential to obtain adequate protection. Provide adequate
ventilation in warehouse or closed storage areas. Air contaminants generated in the
workplace possess varying "escape" velocities which, in turn, determine the "capture
velocities" of fresh circulating air required to effectively remove the contaminant.
Type of Contaminant: Air Speed:
solvent, vapours, degreasing etc., evaporating 0.25- 0.5 m/s (50- 100 f/min)
from tank (in still air).
aerosols, fumes from pouring operations, 0.5- 1 m/s (100- 200 f/min.)
intermittent container filling, low speed
conveyer transfers, welding, spray drift,
plating acid fumes, pickling (released at low
velocity into zone of active generation)
direct spray, spray painting in shallow booths, 1- 2.5 m/s (200- 500 f/min.)
drum filling, conveyer loading, crusher dusts,
gas discharge (active generation into zone of
rapid air motion)
grinding, abrasive blasting, tumbling, high 2.5- 10 m/s (500- 2000 f/min.)
speed wheel generated dusts (released at high
initial velocity into zone of very high rapid
air motion).
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only.
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood- local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
source. The air velocity at the extraction fan, for example, should be a minimum of 1-2
m/s (200-400 f/min) for extraction of solvents generated in a tank 2 meters distant from
the extraction point. Other mechanical considerations, producing performance deficits
within the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or used.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Clear, colourless liquid; mixes with water and alcohol.
PHYSICAL PROPERTIES
Liquid.
Mixes with water.
Molecular Weight: 104.12 Boiling Range (掳C): 182
Melting Range (掳C): Not available Specific Gravity (water=1): 1.108
Solubility in water (g/L): Miscible pH (as supplied): Not available
MONO ETHYLENE GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 35231
NC317TCP Version No:2.0
CD 2007/3 Page 8 of 9
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
pH (1% solution): Not available Vapour Pressure (kPa): Not available
Volatile Component (%vol): Not available Evaporation Rate: Not available
Relative Vapour Density (air=1): Not available Flash Point (掳C): 88.33
Lower Explosive Limit (%): Not available Upper Explosive Limit (%): Not available
Autoignition Temp (掳C): Not available Decomposition Temp (掳C): Not available
State: Liquid
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
路 Presence of incompatible materials.
路 Product is considered stable.
路 Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
Considered an unlikely route of entry in commercial/industrial environments.
The liquid is discomforting to the gastro-intestinal tract.
Ingestion may result in nausea, pain, vomiting. Vomit entering the lungs by aspiration
may cause potentially lethal chemical pneumonitis.
EYE
The liquid is highly discomforting to the eyes and is capable of causing pain and severe
conjunctivitis. Corneal injury may develop, with possible permanent impairment of vision,
if not promptly and adequately treated.
The vapour is highly discomforting to the eyes.
The material may produce severe irritation to the eye causing pronounced inflammation.
Repeated or prolonged exposure to irritants may produce conjunctivitis.
SKIN
The liquid is mildly discomforting to the skin.
Open cuts, abraded or irritated skin should not be exposed to this material. The material
may accentuate any pre-existing skin condition.
INHALED
The vapour is discomforting to the upper respiratory tract.
Inhalation hazard is increased at higher temperatures.
Inhalation of high concentrations of gas/vapour causes lung irritation with coughing and
nausea, central nervous depression with headache and dizziness, slowing of reflexes,
fatigue and inco-ordination.
CHRONIC HEALTH EFFECTS
Principal routes of exposure are usually by skin contact/absorption and inhalation of
vapour.
The material may accumulate in the human body and progressively cause
tissue damage.
Chronic solvent inhalation exposures may result in nervous system impairment and liver
and blood changes. [PATTYS].
As with any chemical product, contact with unprotected bare skin; inhalation of vapour,
mist or dust in work place atmosphere; or ingestion in any form, should be avoided by
observing good occupational work practice.
MONO ETHYLENE GLYCOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 35231
NC317TCP Version No:2.0
CD 2007/3 Page 9 of 9
Section 11 - TOXICOLOGICAL INFORMATION
TOXICITY AND IRRITATION
TOXICITY IRRITATION
Oral (rat) LD50: 8250 mg/kg Eye (rabbit): 100 mg - SEVERE
Intraperitoneal (mouse) LD50: 1310 mg/kg
Oral (guinea pig) LD50: 3800 mg/kg
Acute pulmonary oedema recorded.
Section 12 - ECOLOGICAL INFORMATION
No data for ethylene glycol monoacetate.
Section 13 - DISPOSAL CONSIDERATIONS
路 Consult manufacturer for recycling options and recycle where possible .
路 Consult State Land Waste Management Authority for disposal.
路 Incinerate residue at an approved site.
路 Recycle containers if possible, or dispose of in an authorised landfill.
Section 14 - TRANSPORTATION INFORMATION
HAZCHEM: None
NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS:UN, IATA,
IMDG
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: None
REGULATIONS
ethylene glycol monoacetate (CAS: 542-59-6) is found on the following regulatory lists;
Australia Inventory of Chemical Substances (AICS)
IMO MARPOL 73/78 (Annex II) - List of Noxious Liquid Substances Carried in Bulk
Section 16 - OTHER INFORMATION
Classification of the preparation and its individual components has drawn on official and
authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 12-May-2005
Print Date: 2-Jan-2008
|