MATERIAL SAFETY DATA SHEET
BOMACILLIN SA
REVISED: Tuesday, September 03, 2002
STATEMENT OF HAZARDOUS NATURE:
Non Hazadous
Company Name and Address:
Pharm Tech Pty Limited
8 Apollo Ave
WEST PYMBLE NSW 2073
Contact Numbers:
Tel: 0500 886 668
Fax: 0500 886 669
Emergency Telephone Numbers:
Pharm Tech Pty Limited
0500 886 668 Anywhere in Australia
OR
Poisons Information Centre:
131126 (Australia-wide)
Section 1 -Identification
Product Name: Bomacillin SA
Other Names: Procaine Penicillin
Manufacturer's Product Code: BCILP, BCIL25
UN Number: None allocated
Dangerous Goods Class/Subsidiary Risk: None allocated
Hazchem Code: None allocated
Poisons Schedule Number: S4
Pack Size and Container Type: 100mL & 250mL PET Bottle
Use:
Major Recommended Uses: For the systemic treatment & control of infections caused
by penicillin sensitive organisms in horses, cattle, sheep, pigs, dogs, and cats.
Major Recommended Method(s) of Al2l21ication:.Injection
Section 2 -Composition I Information on Ingredients
Ingredient CAS.
Procaine Penicillin Unknown
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Exposure Guidelines: PEL and TLV not established.
Section 3 -Hazards Identification
Appearance: White to cream liquid
Physical State: Liquid
Odor: Odorless
Emergency Overview
Primary Physical and Health Hazards: N/A
Caution Statement: N/A
Routes of Entry: N/A.
Potential Signs and Symptoms of Occupational Exposure: N/A
Medical Conditions Aggravated by Exposure: N/A.
Carcinogenicity: Bomacillin SA -Not listed by IARC, NTP, ACGIH, or OSHA.
Section 4 -First Aid Measures
Eyes: N/A
Skin: N/A
Inhalation: N/A
Ingestion: Do not induce vomiting. Call a physician or Poisons Information Centre. If
available, administer activated charcoal (6-8 heaping teaspoons) with two to three glasses
of water. Do not give anything by mouth to an unconscious person. Immediately transport
to a medical care facility and see a physician.
Section 5 -Fire Fighting Measures
Flash Point: Not applicable.
VEL: No applicable information found.
LEL: No ignition up to 0.605 ozlcu ft.
Extinguishing Media: Use water, carbon dioxide, dry chemical, foam, or Halon.
Unusual Fire and Explosion Hazards: N/A.
Hazardous Combustion Products: May emit toxic fumes when exposed to heat or fire.
Additional Information: Minimum Ignition Temperature of Dust Layer: 160掳C (320掳F)
Section 6 -Accidental Release Measures
Spills: Contain dry material by lightly misting with water, followed by sweeping up or
vacuuming. Vacuuming may disperse dust if appropriate dust collection filter is not part of
the vacuum. Be aware of potential for dust explosion when using electrical equipment.
Wear protective equipment, including eye protection, to avoid exposure (see Section 8 for
specific handling precautions).
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Section 7 -Handling and Storage 1
Storage: Store below 25掳C (Air Conditioning) in a dry place.
Section 8 -Exposure Controls / Personal Protection
See Section 2 for Exposure Guideline information.
Respiratory Protection: Use an approved respirator.
Eye Protection: Chemical goggles and/or face shield.
Ventilation: Laboratory fume hood or local exhaust ventilation.
Other Protective Equipment: Chemical-resistant gloves and body covering to minimize
skin contact. If handled in a ventilated enclosure, as in a laboratory setting, respirator and
goggles or face shield may not be required. Safety glasses are always required.
Other Handling Precautions: In production settings, airline-supplied, hood-type
respirators are preferred. Shower and change clothing if skin contact occurs.
Section 9 -Physical and Chemical Properties
Boiling Point: Not applicable.
Melting Point: No applicable information found.
Specific Gravity: Not applicable.
pH: 4.5- 7.2 (2.5% aqueous).
Evaporation Rate: No applicable information found.
Water Solubility: Soluble.
Vapor Density: No applicable information found.
Vapor Pressure: No applicable information found.
Section 10 -Stability and Reactivity
Stability: Stable at normal temperatures and pressures.
Incompatibility: May react with strong oxidizing agents (e.g., peroxides, permanganates,
nitric acid, etc.).
Hazardous Decomposition: May emit toxic fumes when heated to decomposition.
Hazardous Polymerization: Will not occur.
Section 11 -Toxicological Information
Animal Toxicity Data Single Exposure
Oral: N/A .
Skin: N/A.
Inhalation: N/A.
Skin Contact: N/A.
Eye Contact: N/A.
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Animal Toxicity Data Repeat Exposure
No data are available for Procaine Penicillin.
Target Organ Effects: Procaine Penicillin -No effects identified in animal studies.
Other Effects: Procaine Penicillin -Salivation, diarrhea, vomiting.
Reproduction: Procaine Penicillin -No effects identified in animal studies.
Sensitization: Procaine Penicillin -Guinea pig, positive contact sensitizer.
Mutagenicity: Procaine Penicillin -Mutagenic in one mammalian test system. Not
mutagenic in bacterial cell tests and other mammalian cell tests. Unlikely to pose a
genotoxic risk to man.
Section 12 -Ecological Information
No data are available for this material. Ecological data for Tylosin base are presented.
Ecotoxicity Data: Procaine Penicillin
Rainbow trout 96-hour median lethal concentration: > 300 mg/L
Bluegill 96-hour median lethal concentration: > 300 mg/L
Daphnia magna 48-hour median effective concentration: > 300 mg/L
Bobwhite 14-day oral median lethal concentration: > 2000 mg/kg
Bobwhite 5-day dietary median lethal concentration: > 5000 ppm
Mallard 5-day dietary median lethal concentration: > 5000 ppm
Earthworm 28-day median lethal concentration: > 102.6 mg/kg
Environmental Fate: Procaine Penicillin
Log Kow: 1.7
Water solubility (g/L): 5
Light absorption in ethanol (nm): 282
Soil degradation half-life (days): 62 for Procaine Penicillin
Soil leaching: none measured
Environmental Summary: Procaine Penicillin -Practically nontoxic to fish, birds,
earthworms, and aquatic invertebrates. No volatility expected. Not expected to
bioconcentrate in aquatic organisms. Low mobility
in soil. Not persistent in the environment due to degradation and possible photolysis.
Section 13 - Disposal Considerations
Waste Disposal: Shake and empty contents into medicated water. Do not dispose of
undiluted chemicals on site. Puncture or shred and bury empty containers in a local
authority landfill. If not available bury the containers below 500 mm in a disposal pit
specifically marked and set up for this purpose clear of waterways, vegetation and roots.
Empty containers and product should not be burnt.
Section 14 - Transport Information
No special transport requirements necessary.
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Section 15 鈥? Other Information
Sections revised: Pharm Tech Telephone Number 0500 886 668
As of the date of issuance, we are providing available information relevant to the handling
of this material in the workplace. All information contained herein is offered with the good
faith belief that it is accurate.
THIS MATERIAL SAFETY DATA SHEET SHALL NOT BE DEEMED TO CREATE ANY
WARRANTY OF ANY KIND (INCLUDING WARRANTY OF MERCHANTABILITY OR
FITNESS FOR A PARTICULAR PURPOSE). In the event of an adverse incident
associated with this material, this safety data sheet is not intended to be a substitute for
consultation with appropriately trained personnel. Nor is this safety data sheet intended to
be a substitute for product literature which may accompany the finished product.
CONTACT POINT:
Pharm Tech Pty Limited 0500 886 668
GLOSSARY
ACGIH = American Conference of Governmental Industrial Hygienists
AlHA = American Industrial Hygiene Association
BEl = Biological Exposure Index
CAS Number = Chemical Abstract Service Registry Number
CERCLA = Comprehensive Environmental Response Compensation and Liability Act (of
1980)
CHEMTREC = Chemical Transportation Emergency Center
DOT = Department of Transportation
EC = European Community
EINECS = European Inventory of Existing Chemical Substances
ELINCS = European List of New Chemical Substances
EP A = Environmental Protection Agency
HEP A = High Efficiency Particulate Air (Filter)
IARC = International Agency for Research on Cancer
ICAO/IATA = International Civil Aviation Organization/International Air Transport
Association
IMO = International Maritime Organization
LEL = Lower Explosive Limit
MSDS = Material Safety Data Sheet
NA = Not Applicable, except in Section 14 where NA = North America
NADA = New Animal Drug Application
NAIF = No Applicable Information Found
NCI = National Cancer Institute
NIOSH = National Institute for Occupational Safety and Health
NOS = Not Otherwise Specified
NTP = National Toxicology Program
OSHA = Occupational Safety and Health Administration
PEL = Permissible Exposure Limit (OSHA)
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RCRA = Resource Conservation and Recovery Act
RQ = Reportable Quantity
RTECS = Registry of Toxic Effects of Chemical Substances
SARA = Superfund Amendments and Reauthorization Act
STEL = Short Term Exposure Limit
TLV = Threshold Limit Value (ACGIH)
TPQ = Threshold Planning Quantity
TSCA = Toxic Substances Control Act
TW A = Time Weighted Average/8 Hours Unless Otherwise Noted
UEL = Upper Explosive Limit
UN = United Nations
WEEL = Workplace Environmental Exposure Level (AIHA)
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