Biopharm Australia Pty Ltd
111 Bronte Road, Bondi Junction, NSW 2022, Australia
ph: +61 (02) 9389 0000 fax: +61 (02) 9387 5473
Material Safety Data Sheet
CARTROPHEN VET Injection
Active Compound: Pentosan Polysulfate Sodium
UN No:
INN.L29D
CAS No:
37319-17-8
Use:
Treatment of osteoarthritis and related conditions
Synonyms:
NaPPS, Sodium Pentosan Polysulfate, ELMIRON
Ingredients:
Pentosan Polysulfate Sodium (10%), Benzyl Alcohol (Preservative, 1%) in a phosphate buffer
Physical Description/Properties
Appearance: Pale yellow, sterile, odourless liquid
Boiling Range: 100潞C
Specific Gravity: 1.07
pH: 6
Flash Point: Non-combustible
Autoignition Temperature: not applicable
Molecular Weight (NaPPS): 4000 - 5000
Formula (NaPPS): 4-O-methyl glucuronoxylan sulfate (sodium salt)
Health Hazard Information
Acute Effects:
Oral LD50 - mice and rats = >35g/kg body weight
I.V. LD50 - mice and rats = >1g/kg body weight
Large overdoses systemically by injection cause a moderate, transient increase in bleeding time
Chronic Effects: Repeated daily overdoses result in anorexia and depression, reversible upon
withdrawal of the drug
First Aid: Not applicable
Precautions for Use
Exposure Standards: Not established
Personal Protection: Not required
Storage and Transport: Store between 2潞 and 8潞C, do not freeze, protect from direct sunlight
Spills and Disposal: Spilt liquid may be flushed down drain. Materials contaminated may be disposed
of in usual waste stream.
Fire/Explosion Hazard: not sensitive to mechanical impact or static charge. Pentosan polysulfate
sodium and its solutions will not burn or support combustion.
Contact Points
Mr Robert L. Hannon - Biopharm Australia Pty Ltd
ph: +61 (02) 9389 0000
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Valid till 01/2004
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