Material Safety Data Sheet
Revision: 05/16/2001
Hazard information is provided for compliance with both the UK Chemicals
(Hazard Information and Packaging) (CHIP) Regulations and t he US Hazard
Communication Standard (HCS)
IDENTIFICATION OF THE PRODUCT NAME: PRODUCT CODE: EEC NUMBER:
SUBSTANCE/PREPARATION Pyridoxine Hydrochloride, Vitamin B 6 20900 None
AND COMPANY
SUPPLIER: Emergency Contact:
USB Corporation, 26111 Miles Road, Cleveland, Ohio 44128 Phone: (216) 765-5000 Chemtrec (800) 424-9300
Outside USA & Canada 703 527 3887
COMPOSITION/
HAZARDOUS COMPONENTS HAZARD CAS NO. %WT TLV CHIP R & S Phrases
Pyridoxine Hydrochloride 58-56-0 ~100% --- R:36/37/38 Irritating to eyes,
respiratory system and skin
S:22 Do not breathe dust
S:24/25 Avoid contact with
skin and eyes
HAZARDS IDENTIFICATION CHIP
Irritant
HCS
Irritant
FIRST-AID MEASURES EYES: Flush with water for 15 minutes. Seek medical advice if irritation persists.
SKIN: Flush with water, then wash thoroughly with soap and water. Remove conta minated clothing and wash
before reuse. Seek medical attention if irritation persists.
INHALATION: Remove the victim from exposure and move to fresh air. If breathing is difficult, give oxygen. If
not breathing, give artificial respiration. Keep victim quiet and warm. Seek immediate medical attention.
INGESTION: Drink water and seek immediate medical attention. Avoid alcoholic beverages. Never give
anything by mouth to an unconscious person.
FIRE-FIGHTING INFORMATION Use media suitable to extinguish the supporting or surrounding fire. Wear NIOSH (or equivalent) approved self
contained breathing apparatus. For small fires only: use carbon dioxide, dry powder or foam. Emits toxic fumes
of carbon monoxide, carbon dioxide, nitrogen and sulfur oxides under conditions of fire. Use appropriate
precaution for dust explosion hazard. Ground all equipment in contact with the dry material.
Flash Point = No data available. Decomposition Temperature = 205掳C.
ACCIDENTAL RELEASE MEASURES Wear appropriate personal protective equipment and clothing including lab coat , safety goggles, gloves and
NIOSH-approved respirator. Collect in a manner that does not create dust and place in a suitable waste
container. Avoid contact of material with skin or eyes. Use adequat e ventilation.
HANDLING AND STORAGE Wear suitable protective clothing including lab coat, safet y goggles, gloves and NIOSH-approved respirator.
Avoid contact of material with skin or eyes. Do not generate dust or expose t o ignition sources. Ground and
bond all transfer equipment. Use adequate ventilation. Store out of direct sunlight in a cool, well ventilated
area.
PERSONAL PROTECTION Wear appropriate personal protective equipment and clothing including lab coat , safety goggles, gloves and
NIOSH-approved respirator. A qualified industrial hygienist should evaluate the need f or respiratory protection.
Use respiratory protection approved by NIOSH (or equivalent) and appropriate to the haza rd. Avoid contact of
material with skin or eyes. Mechanical ventilation or local exhaust as needed to control exposure to dust,
vapors or mists. Access to a safety shower and eye-wash.
This data sheet is based upon information believed to be reliable. The Company makes no statement or warranty as to the accuracy or completeness of the information
contained herein which is offered for your consideration, investigation and verification. Any use of the information contained in this data sheet must be determined by the user
to be in accordance with appropriate applicable regulations.
For Further Asia Pacific Canada Former Soviet Union Japan Norway Spain USA
Information, +852 2811 8693 1 800 463 5800 +7 (095) 232 0250 81 3 5331 9337 63 89 23 10 935 944 950 USB Corporation
contact your (216) 765-5000
local USB Australia Central and East Europe France Latin America Portugal Sweden If purchased from
authorized +61 2 9894 5188 +43 1 982 3826 0169 18 28 00 +55 11 3667 5700 01 417 70 35 018 164000 Amersham Pharmacia
distributor, Biotech use
Amersham Austria Denmark Germany Middle East and Africa South East Asia Switzerland 1 800 526 3593
Pharmacia 01 576 0616 10 +45 4516 2400 07 61 49 03 0 +30 (1) 96 00 687 60 3 724 2080 01 802 81 50
Biotech
Belgium Finland Italy Netherlands South East Europe UK
0800 73888 358 (9) 512 3940 02 27322 1 0165 580 410 +43 (1) 982 3826 0800 515313
MSDS information may be continued on back of page.
PHYSICAL AND CHEMICAL Appearance: White crystalline solid, odorless Boiling Point: No data available
Vapor Pressure: No data available Vapor Density: 7.1
PROPERTIES
Solubility (Water): Soluble Specific Gravity: 0.36 kg/l (bulk)
Percent Volatile: No data available Evaporation Rate: No data available
Chemical formula: C8-H11-N-O3 @ HCl Melting Point: 202-206掳C
STABILITY AND REACTIVITY Product is stable. Caution: material is light sensitive. Avoid light, neutral aqueous solutions, hea t (may cause
dimerization and irradiation in neutral or alkaline solutions. Incompatible with strong oxidizing agent s, bases,
iron, heavy metals, trace minerals and chloride gas. Hazardous decomposition products include ca rbon and
nitrogen oxides and hydrogen chloride gas. Hazardous polymerization will not occur.
TOXICOLOGICAL INFORMATION EFFECTS OF OVEREXPOSURE: To the best of our knowledge the chemical, physical and toxicological
properties have not been thoroughly investigated.
EYES: May cause irritation.
SKIN: May cause skin irritation.
INHALATION: Excessive dust may cause irritation to mucous me mbranes and upper respiratory tract.
INGESTION: Chronic ingestion or excessive dosage may cause nausea , vomiting, insomnia, urine discoloration,
ataxia and peripheral sensory neuropathy (deterioration of nerves and nerve tissue).
ADDITIONAL INFORMATION:
Reproductive effects, mutation and toxicity data listed in RTECS under UV1350000.
Oral Rat LD50 = 4 gm/kg (1961). Toxic effect s may included convulsions, dyspnea, hypermotility, diarrhea,
ataxia and muscle weakness.
Reproductive: Effects on newborn - biochemical and metabolic (1974 ).
Specific developmental abnormalities - central nervous system (1974).
Maternal effects - postpartum (1983).
Paternal effects - testes, epididymis, sperm duct, prostate, seminal ve sicle, Cowper鈥檚 glandand
spermatogenesis (1992).
Definition(s): RTECS = Registry of Toxic Effects of Chemica l Substances.
ECOLOGICAL INFORMATION No information available
DISPOSAL CONSIDERATIONS Dispose of material in accordance with applicable local, stat e, and federal regulations.
TRANSPORTATION INFORMATION US DOT / IATA: No applicable information.
REGULATORY INFORMATION RCRA - No applicable information.
SARA 302 -This material does not have an RQ or TPQ.
SARA 313 -This material is not reportable under 313.
Exposure Limits - Not established.
EPA TSCA Section 8(b) - Chemical Inventory.
California Proposition 65 - No applicable information.
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