Material Safety Data Sheet
Revision: 08/30/2004
Hazard information is provided for compliance with both the UK Chemicals
(Hazard Information and Packaging) (CHIP) Regulations and the US Hazard
Communication Standard (HCS)
IDENTIFICATION OF THE PRODUCT NAME: PRODUCT CODE: EEC NUMBER:
SUBSTANCE/PREPARATION Vitamin B12 - 0.1% Trituration in Mannitol 23370 200-680-0
AND COMPANY (Cyanocobalamin)
SUPPLIER: Emergency Contact:
USB Corporation, 26111 Miles Road, Cleveland, Ohio 44128 Phone: (216) 765-5000 Chemtrec (800) 424-9300
Please visit our website at www.usbweb.com for contact information on USB Outside USA & Canada 703 527 388
product distributors within your area.
COMPOSITION/
HAZARDOUS COMPONENTS HAZARD CAS NO. %WT TLV CHIP R & S Phrases
Vitamin B12 68-19-9 0.1% 鈥? R:36/37/38 Irritating to eyes,
respiratory system and skin.
S:22 Do not breathe dust.
S:36/37 Wear suitable
protective clothing and gloves.
HAZARDS IDENTIFICATION CHIP
Irritant
HCS
Irritant
FIRST-AID MEASURES EYES: Flush with water for 15 minutes. Seek medical advice if irritation persists.
SKIN: Flush with water, then wash thoroughly with soap and water. Remove contaminated clothing and
wash before reuse. Seek medical attention if irritation persists.
INHALATION: Remove the victim from exposure and move to fresh air. If breathing is difficult, give
oxygen. If not breathing, give artificial respiration. Keep victim quiet and warm. Seek immediate
medical attention.
INGESTION: Drink water and seek immediate medical attention. Avoid alcoholic beverages. Never give
anything by mouth to an unconscious person.
FIRE-FIGHTING INFORMATION Use media suitable to extinguish the supporting or surrounding fire. Wear NIOSH (or equivalent) approved self
contained breathing apparatus. For small fires only: use carbon dioxide, dry powder or foam. Avoid dusting
since all organic dusts can be explosive under certain conditions. Emits toxic fumes under fire conditions.
Flash Point = No data available.
ACCIDENTAL RELEASE MEASURES Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and
NIOSH-approved respirator. Collect in a manner that does not create dust and place in a suitable waste
container. Avoid contact of material with skin or eyes. Use adequate ventilation.
HANDLING AND STORAGE Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and
NIOSH-approved respirator. Avoid contact of material with skin or eyes. Use adequate ventilation. Light
Sensitive. Hygroscopic. Store ambient away from incompatible materials.
PERSONAL PROTECTION Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and
NIOSH-approved respirator. A qualified industrial hygienist should evaluate the need for respiratory protection.
Use respiratory protection approved by NIOSH (or equivalent) and appropriate to the hazard. Avoid contact of
material with skin or eyes. Mechanical ventilation or local exhaust as needed to control exposure to dust,
vapors or mists. Access to a safety shower and eye-wash.
PHYSICAL AND CHEMICAL Appearance: Tan/ slight pink powder Boiling Point: No data available
PROPERTIES Vapor Pressure: No data available Vapor Density: No data available
Solubility (Water): Soluble Specific Gravity: No data available
Percent Volatile: No data available Evaporation Rate: No data available
Chemical formula: C63-H88-Co-N14-O14-P
STABILITY AND REACTIVITY Product is stable. Hygroscopic. May decompose on exposure to light. Protect from light. Hazardous
decomposition products include carbon, nitrogen and phosphorus oxides. Incompatible with strong oxides and
strong acids. Hazardous polymerization will not occur.
MSDS information may be continued on back of page.
TOXICOLOGICAL INFORMATION EFFECTS OF OVEREXPOSURE:
EYES: Contact may cause irritation.
SKIN: Contact may cause irritation. May cause skin sensitization, an allergic reaction, which becomes evident
upon re-exposure to this material.
INHALATION: May cause irritation to mucous membranes and upper respiratory tract.
INGESTION: Chronic ingestion or excessive dosage may cause gastrointestinal irritation with nausea, vomiting
and diarrhea. Ingestion of large amounts may cause convulsions, tremors, muscular contractions or spasticity,
urine discoloration, ataxia, peripheral sensory neuropathy or fever.
ADDITIONAL INFORMATION:
Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals. Animal studies
have reported that fetal effects/abnormalities may occur when maternal toxicity is seen.
Reproductive effects and toxicity data is listed in RTECS under GG3750000.
Oral Mouse LD= >5 gm/kg (1992). Details of toxic effects not reported other than lethal dose value.
Reproductive: Effects on newborn - growth statistics (e.g.%, reduced weight gain), biochemical and
metabolic (1973).
Effects on embryo or fetus - fetotoxicity (except death, e.g., stunted fetus) (1978).
Specific developmental abnormalities - musculoskeletal and urogenital systems (1978).
Definition(s): RTECS = Registry of Toxic Effects of Chemical Substances.
ECOLOGICAL INFORMATION No information available
DISPOSAL CONSIDERATIONS Dispose of material in accordance with applicable local, state, and federal regulations.
TRANSPORTATION INFORMATION US DOT / IATA: No information available.
REGULATORY INFORMATION RCRA - No applicable information.
SARA 302 - This material does not have an RQ or TPQ.
SARA 313 - This material contains Cyanocobalamin (listed as Cobalt compounds), 0.1%, (CAS# 68-19-9)
which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
EPA TSCA Section 8(b) - Chemical Inventory.
Exposure Limits - Not established.
California Proposition 65 - No applicable information.
This data sheet is based upon information believed to be reliable. The Company makes no statement or warranty as to the accuracy or completeness of the
information contained herein which is offered for your consideration, investigation and verification. Any use of the information contained in this data sheet
must be determined by the user to be in accordance with appropriate applicable regulations.
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