Material Safety Data Sheet
Revision: 12/28/2005
Hazard information is provided for compliance with both the UK Chemicals
(Hazard Information and Packaging) (CHIP) Regulations and the US Hazard
Communication Standard (HCS)
IDENTIFICATION OF THE PRODUCT NAME: PRODUCT CODE: EEC NUMBER:
FideliTaqTM DNA Polymerase
SUBSTANCE/PREPARATION 71180 None
AND COMPANY
SUPPLIER: Emergency Contact:
USB Corporation, 26111 Miles Road, Cleveland, Ohio 44128 Phone: (216) 765-5000 Chemtrec (800) 424-9300
Please visit our website at www.usbweb.com for contact information on USB Outside USA & Canada 703 527 3887
product distributors within your area.
COMPOSITION/
HAZARDOUS COMPONENTS HAZARD CAS NO. %WT TLV CHIP R & S Phrases
For Buffer 71165: For the mixture / preparation:
Tris 77-86-1 ~1.2% 鈥? R:36/37/38 Irritating to eyes,
respiratory system and skin.
Potassium Chloride 7447-40-7 ~3.7% 鈥? S:24/25 Avoid contact with
skin and eyes.
S:36/37 Wear suitable
protective clothing and gloves.
For FideliTaq 71180:
Glycerol 56-81-5 ~50% See R:36/37/38 Irritating to eyes,
鈥淩egulatory respiratory system and skin.
Information鈥? S:36/37 Wear suitable
Section protective clothing and gloves.
HAZARDS IDENTIFICATION CHIP
Irritant
HCS
Irritant
FIRST-AID MEASURES EYES: Flush with water for 15 minutes. Seek medical advice if irritation persists.
SKIN: Flush with water, then wash thoroughly with soap and water. Remove contaminated clothing and wash
before reuse. Seek medical attention if irritation persists.
INHALATION: Remove the victim from exposure and move to fresh air. If breathing is difficult, give oxygen.
If not breathing, give artificial respiration. Keep victim quiet and warm. Seek immediate medical attention.
INGESTION: Drink water and seek immediate medical attention. Avoid alcoholic beverages. Never give
anything by mouth to an unconscious person.
FIRE-FIGHTING INFORMATION Use media suitable to extinguish the supporting or surrounding fire. Wear NIOSH (or equivalent) approved self
contained breathing apparatus. For small fires only: use carbon dioxide, dry powder or foam. May emit toxic fumes
under fire conditions.
Flash Point = No data available.
ACCIDENTAL RELEASE MEASURES Wear appropriate personal protective equipment and clothing including lab coat, safety glasses, gloves and NIOSH-
approved respirator. Contain the spill with an inert absorbent and place in a suitable waste container. Avoid contact
of material with skin or eyes. Use adequate ventilation.
HANDLING AND STORAGE Wear appropriate personal protective equipment and clothing including lab coat, safety glasses, gloves and NIOSH-
approved respirator. Use adequate ventilation. Avoid contact of material with skin or eyes. Store at -20掳C away
from incompatible materials.
PERSONAL PROTECTION Wear appropriate personal protective equipment and clothing including lab coat, safety glasses, gloves and NIOSH-
approved respirator. A qualified industrial hygienist should evaluate the need for respiratory protection. Use
respiratory protection approved by NIOSH (or equivalent) and appropriate to the hazard. Avoid contact of material
with skin or eyes. Mechanical ventilation or local exhaust as needed to control exposure to dust, vapors or mists.
Access to a safety shower and eye-wash.
PHYSICAL AND CHEMICAL Appearance: Vials of solutions Boiling Point: No data available
PROPERTIES Vapor Pressure: No data available Vapor Density: No data available
Solubility (Water): All components are soluble Specific Gravity: No data available
Percent Volatile: No data available Evaporation Rate: No data available
Chemical formula: Not applicable
MSDS information may be continued on back of page.
STABILITY AND REACTIVITY Product is stable under normal conditions. Avoid prolonged excessive heat which may cause decomposition. Store
away from strong bases, strong acids, and strong oxidizing agents. Burning can produce carbon monoxide and/or
carbon dioxide. Hazardous polymerization will not occur.
TOXICOLOGICAL INFORMATION EFFECTS OF OVEREXPOSURE TO 71165:
EYES: Contact may cause irritation and slight corneal injury.
SKIN: Contact may cause irritation and/or allergic reaction.
INHALATION: May cause irritation to the nose, throat and mucous membranes of the respiratory tract.
INGESTION: Chronic ingestion or excessive dosage may cause abdominal discomfort, nausea, vomiting and
diarrhea.
ADDITIONAL INFORMATION:
Tris - Toxicity data for Tris is listed in RTECS under TY2900000.
Potassium Chloride - Irritation, mutation and toxicity data for KCl is listed in RTECS under TS8050000.
EFFECTS OF OVEREXPOSURE TO 71180 (Glycerol):
EYES: Contact may cause irritation and slight corneal injury.
SKIN: Prolonged contact may cause irritation and/or allergic reaction.
INHALATION: No known toxicity, but excessive fumes may cause irritation if inhaled.
INGESTION: May cause irritation to gastrointestinal tract and diarrhea.
ADDITIONAL INFORMATION:
May cause slight or transient irritation to eyes and skin. Has caused moderate irritation in dermal (rabbit)
studies. Irritation, mutation, reproductive effects and toxicity data for Glycerol is listed in RTECS under
MA8050000.
Oral rat LD50 = 12,600 mg/kg.
ACGIH TLV-TWA: 10 mg/m3 (total particulate)
OSHA TWA: 15 mg/m3 (total dust)
Definition(s): RTECS = Registry of Toxic Effects of Chemical Substances.
ACGIH = American Conference of Governmental Industrial Hygienists.
NIOSH = National Institute for Occupational Safety and Health.
ECOLOGICAL INFORMATION No information available.
DISPOSAL CONSIDERATIONS Dispose of material in accordance with applicable local, state, and federal regulations.
TRANSPORTATION INFORMATION US DOT / IATA: No applicable information.
REGULATORY INFORMATION RCRA - No applicable information.
SARA 302 - No applicable information.
SARA 313 - No applicable information.
EPA TSCA Section 8(b) - For Glycerol, Tris and Potassium Chloride: Chemical Inventory.
Exposure Limits - For Glycerol: ACGIH TLV-TWA 10 mg/m3 (total particulate).
OSHA PEL TWA: 15 mg/m3 (total dust).
California Proposition 65 - No applicable information.
This data sheet is based upon information believed to be reliable. The Company makes no statement or warranty as to the accuracy or completeness of the
information contained herein which is offered for your consideration, investigation and verification. Any use of the information contained in this data sheet
must be determined by the user to be in accordance with appropriate applicable regulations.
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