SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/14/2005
Date Updated: 04/10/2004
Version 1.8
Section 1 - Product and Company Information
Product Name 2,4-DINITROPHENYLHYDRAZINE,
REAGENT GRADE, 97%
Product Number D199303
Brand ALDRICH
Company Sigma-Aldrich
Street Address 3050 Spruce Street
City, State, Zip, Country SAINT LOUIS MO 63103 US
Technical Phone: 314 771 5765
Emergency Phone: 414 273 3850 Ext. 5996
Fax: 800 325 5052
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
2,4-DINITROPHENYLHYDRAZINE, 119-26-6 No
MOISTENED
Formula C6H6N4O4
Synonyms 2,4-Dinitrofenylhydrazin (Czech) *
2,4-Dinitrophenylhydrazine * 2,4-Dnph
RTECS Number: MV3325000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Toxic (USA) Harmful (EU). Flammable (USA) Highly Flammable (EU).
Explosive when dry. Highly flammable. Harmful if swallowed.
Target organ(s): Blood.
HMIS RATING
HEALTH: 2*
FLAMMABILITY: 2
REACTIVITY: 3
NFPA RATING
HEALTH: 2
FLAMMABILITY: 2
REACTIVITY: 3
*additional chronic hazards present.
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
Section 5 - Fire Fighting Measures
FLAMMABLE HAZARDS
Flammable Hazards: Yes
EXPLOSION HAZARDS
Dry material is an explosive.
EXPLOSION DATA
Sensitivity to Mechanical Impact: May be shock-sensitive if dry.
Dust Potential: This material, like most materials in powder
form, is capable of creating a dust explosion.
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Flammable solid. Emits toxic fumes under
fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition. Use nonsparking
tools.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Avoid raising dust. Sweep up, place in a bag and hold for waste
disposal. Ventilate area and wash spill site after material
pickup is complete.
Section 7 - Handling and Storage
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HANDLING
User Exposure: Avoid contact with eyes, skin, and clothing.
Avoid breathing dust. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep container closed. Keep away from heat, sparks,
and open flame.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Mechanical
exhaust required.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Government approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
Section 9 - Physical/Chemical Properties
Appearance Physical State: Solid
Color: Red
Form: Powder
Property Value At Temperature or Pressure
Molecular Weight 198.14 AMU
pH N/A
BP/BP Range N/A
MP/MP Range 200 - 202 掳C
Freezing Point N/A
Vapor Pressure N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density N/A
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
Solubility Solvent: 10 mg/ml H2SO4 50% complete and
clear
N/A = not available
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Section 10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: May be shock-sensitive if dry.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. May be harmful if inhaled.
Ingestion: Harmful if swallowed.
TARGET ORGAN(S) OR SYSTEM(S)
Blood.
SIGNS AND SYMPTOMS OF EXPOSURE
Absorption into the body leads to the formation of methemoglobin
which in sufficient concentration causes cyanosis. Onset may be
delayed 2 to 4 hours or longer.
TOXICITY DATA
Oral
Rat
500 mg/kg
LD50
Intraperitoneal
Mouse
450 MG/KG
LD50
IRRITATION DATA
Eyes
Rabbit
500 mg
24H
Remarks: Mild irritation effect
CHRONIC EXPOSURE - MUTAGEN
Species: Rat
Dose: 50 MG/L
Cell Type: liver
Mutation test: Unscheduled DNA synthesis
Species: Mouse
Route: Intraperitoneal
Dose: 1900 UMOL/KG
Mutation test: DNA damage
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Mutation test: Histidine reversion (Ames)
Section 12 - Ecological Information
No data available.
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Burn in a chemical incinerator equipped with an
afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and
local environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: Flammable solids, organic, n.o.s.
UN#: 1325
Class: 4.1
Packing Group: Packing Group II
Hazard Label: Flammable solid
PIH: Not PIH
IATA
Proper Shipping Name: Flammable solid, organic, n.o.s.
IATA UN Number: 1325
Hazard Class: 4.1
Packing Group: II
Section 15 - Regulatory Information
EU ADDITIONAL CLASSIFICATION
Symbol of Danger: Xn F
Indication of Danger: Harmful. Highly Flammable.
R: 1 11 22
Risk Statements: Explosive when dry. Highly flammable. Harmful
if swallowed.
S: 35
Safety Statements: This material and its container must be
disposed of in a safe way.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Toxic (USA) Harmful (EU). Flammable (USA)
Highly Flammable (EU).
Risk Statements: Explosive when dry. Highly flammable. Harmful
if swallowed.
Safety Statements: Keep away from sources of ignition - no
smoking. This material and its container must be disposed of in
a safe way.
US Statements: Target organ(s): Blood.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
TSCA INVENTORY ITEM: Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
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DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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