SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/18/2005
Date Updated: 04/04/2004
Version 1.5
Section 1 - Product and Company Information
Product Name ALUMINUM CHLORIDE HEXAHYDRATE,
REAGENTPLUS(TM), 99%
Product Number 237078
Brand ALDRICH
Company Sigma-Aldrich
Street Address 3050 Spruce Street
City, State, Zip, Country SAINT LOUIS MO 63103 US
Technical Phone: 314 771 5765
Emergency Phone: 414 273 3850 Ext. 5996
Fax: 800 325 5052
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
ALUMINUM CHLORIDE HEXAHYDRATE 7784-13-6 No
Formula AlCl3 藝 6H2O
Synonyms Aluminum(III) chloride, hexahydrate * Aluminum
trichloride hexahydrate
RTECS Number: BD0530000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Corrosive.
Causes burns.
HMIS RATING
HEALTH: 3
FLAMMABILITY: 0
REACTIVITY: 0
NFPA RATING
HEALTH: 3
FLAMMABILITY: 0
REACTIVITY: 0
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately. Do not induce vomiting.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
Section 5 - Fire Fighting Measures
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Ventilate
area and wash spill site after material pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe dust. Do not get in eyes, on skin,
on clothing. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep tightly closed. Store in a cool dry place.
Incompatible Materials: Caution: the anhydrous form of this
material has been reported to have the following hazards
associated with it. Prolonged storage of anhydrous aluminum
chloride in closed containers has resulted in spontaneous
decomposition and occasional explosion upon opening the
container probably due to the diffusion of moisture into the
container with resulting pressure build-up due to liberated
hydrogen chloride gas. When heated in a sealed tube, high
internal pressure may be generated due to not only its vapor
pressure and pressure of desorbed hydrogen chloride, but also by
the near doubling in volume which occurs when the material melts
to the monomer. Mixtures of nitrobenzene and aluminum chloride
are thermally unstable and may lead to explosive decomposition
due to a multi-step decomposition reaction occurring above 90藲C,
which self-accelerates with high exothermicity producing azo-
and azoxypolymers. Violent exothermic reactions can occur upon
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aluminum chloride contacting: alkenes, a mixture of benzoyl
chloride and naphthalene, a mixture of aniline and
ethyleneimine, ethylene oxide, a mixture of sodium peroxide and
aluminum. Aluminum chloride reacts explosively with: oxygen
difluoride, phenyl azide, perchloryl benzene or sodium
borohydride.
SPECIAL REQUIREMENTS
Moisture sensitive.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Government approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated
shoes. Wash thoroughly after handling.
EXPOSURE LIMITS, RTECS
Country Source Type Value
USA ACGIH TWA 2 MG(AL)/M3
Section 9 - Physical/Chemical Properties
Appearance Physical State: Solid
Color: Colorless
Form: Fine crystals
Property Value At Temperature or Pressure
Molecular Weight 241.43 AMU
pH 2.5 - 3.5 20 藲C
BP/BP Range N/A
MP/MP Range 100 藲C
Freezing Point N/A
Vapor Pressure 1 mmHg 100 藲C
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density 2.398 g/cm3
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
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Miscellaneous Data N/A
Solubility N/A
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Conditions of Instability: May decompose on exposure to moist air
or water.
Materials to Avoid: Strong acids.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Hydrogen chloride gas, Aluminum
oxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: Causes burns.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes burns.
Inhalation: Material is extremely destructive to the tissue of
the mucous membranes and upper respiratory tract. May be harmful
if inhaled.
Ingestion: May be harmful if swallowed.
SIGNS AND SYMPTOMS OF EXPOSURE
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. Material is extremely destructive to tissue of the
mucous membranes and upper respiratory tract, eyes, and skin. To
the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
TOXICITY DATA
Oral
Rat
3311 mg/kg
LD50
Intraperitoneal
Rat
728 MG/KG
LD50
Oral
Mouse
1990 mg/kg
LD50
Intraperitoneal
Mouse
940 MG/KG
LD50
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IRRITATION DATA
Skin
Human
7.5 mg
3D
I
Remarks: Mild irritation effect
CHRONIC EXPOSURE - TERATOGEN
Species: Mouse
Dose: 483 GM/KG
Route of Application: Intravenous
Exposure Time: (8D PREG)
Result: Specific Developmental Abnormalities: Musculoskeletal
system. Specific Developmental Abnormalities: Other
developmental abnormalities.
CHRONIC EXPOSURE - MUTAGEN
Species: Mammal
Dose: 40 UMOL/L
Cell Type: lymphocyte
Mutation test: DNA damage
Section 12 - Ecological Information
ACUTE ECOTOXICITY TESTS
Test Type: LC50 Fish
Species: other fish
Time: 96 h
Value: 27.1 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 27.3 mg/l
ADDITIONAL RESULTS/DATA FROM RELEVENT SCIENTIFIC EXPERIMENTS
May be harmful to aquatic organisms due to the shift
of the pH. Avoid contamination of the environment
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: Corrosive solid, acidic,
inorganic, n.o.s.
UN#: 3260
Class: 8
Packing Group: Packing Group III
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Hazard Label: Corrosive
PIH: Not PIH
IATA
Proper Shipping Name: Corrosive solid, acidic,
inorganic, n.o.s.
IATA UN Number: 3260
Hazard Class: 8
Packing Group: III
Section 15 - Regulatory Information
EU ADDITIONAL CLASSIFICATION
Symbol of Danger: C
Indication of Danger: Corrosive.
R: 34
Risk Statements: Causes burns.
S: 26 36/37/39 45
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
suitable protective clothing, gloves, and eye/face protection.
In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Corrosive.
Risk Statements: Causes burns.
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
suitable protective clothing, gloves, and eye/face protection.
In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: No
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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