SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/14/2005
Date Updated: 03/10/2005
Version 1.9
Section 1 - Product and Company Information
Product Name BENZYL ALCOHOL, 99+%, A.C.S.
REAGENT
Product Number 402834
Brand ALDRICH
Company Sigma-Aldrich
Street Address 3050 Spruce Street
City, State, Zip, Country SAINT LOUIS MO 63103 US
Technical Phone: 314 771 5765
Emergency Phone: 414 273 3850 Ext. 5996
Fax: 800 325 5052
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
BENZYL ALCOHOL 100-51-6 No
Formula C7H8O
Synonyms Benzal alcohol * Benzenecarbinol *
Benzenemethanol * Benzoyl alcohol *
Hydroxytoluene * alpha-Hydroxytoluene * Methanol,
phenyl- * NCI-C06111 * Phenolcarbinol *
Phenylcarbinol * Phenylmethanol * Phenylmethyl
alcohol * alpha-Toluenol
RTECS Number: DN3150000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Harmful.
Harmful by inhalation and if swallowed. Irritating to skin.
Target organ(s): Central nervous system.
HMIS RATING
HEALTH: 2*
FLAMMABILITY: 1
REACTIVITY: 1
NFPA RATING
HEALTH: 2
FLAMMABILITY: 1
REACTIVITY: 1
*additional chronic hazards present.
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
DERMAL EXPOSURE
In case of contact, immediately wash skin with soap and copious
amounts of water.
EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
Section 5 - Fire Fighting Measures
FLASH POINT
204.8 掳F 96 掳C Method: closed cup
AUTOIGNITION TEMP
436 掳C
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe vapor. Avoid contact with eyes,
skin, and clothing. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep tightly closed. Handle and store under nitrogen.
Store in a cool dry place.
SPECIAL REQUIREMENTS
Handle and store under inert gas. Hygroscopic.
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Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Government approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 240 mg/m3
Poland NDSCh -
Poland NDSP
Section 9 - Physical/Chemical Properties
Appearance Physical State: Clear liquid
Color: Colorless
Property Value At Temperature or Pressure
Molecular Weight 108.14 AMU
pH N/A
BP/BP Range 90 - 93 掳C 10 mmHg
MP/MP Range -16 掳C
Freezing Point N/A
Vapor Pressure 3.75 mmHg 77 掳C
Vapor Density 3.7 g/l
Saturated Vapor Conc. N/A
SG/Density 1.044 g/cm3
Bulk Density N/A
Odor Threshold 5.5 ppm
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity 0.005 Pas 25 掳C
Surface Tension 39 mN/m 20 掳C
Partition Coefficient Log Kow: 1.1
Decomposition Temp. N/A
Flash Point 204.8 掳F 96 掳C Method: closed cup
Explosion Limits N/A
Flammability N/A
Autoignition Temp 436 掳C
Refractive Index 1.54
Optical Rotation N/A
Miscellaneous Data N/A
Solubility Solubility in Water:33 mg/ml H2O, 20掳C
clear, colorless
Other Solvents: SOLUBLE IN ETHANOL, ETHER
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
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Stable: Stable.
Conditions of Instability: Hygroscopic.
Conditions to Avoid: A mixture of benzyl alcohol and 58% sulfuric
acid decomposed violently when heated to 180掳C. Benzyl alcohol
containing 1.4% hydrogen bromide and 1.1% of an iron(II) salt
polymerized exothermally when heated above 100掳C.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: Harmful if inhaled. Material may be irritating to
mucous membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.
TARGET ORGAN(S) OR SYSTEM(S)
Central nervous system.
SIGNS AND SYMPTOMS OF EXPOSURE
Can cause CNS depression.
TOXICITY DATA
Oral
Rat
1230 mg/kg
LD50
Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Excitement. Behavioral:Coma.
Intraperitoneal
Rat
400 MG/KG
LD50
Intravenous
Rat
53 MG/KG
LD50
Remarks: Lungs, Thorax, or Respiration:Dyspnea.
Intraarterial
Rat
441 MG/KG
LD50
Remarks: Lungs, Thorax, or Respiration:Chronic pulmonary edema.
Lungs, Thorax, or Respiration:Dyspnea.
Oral
Mouse
1360 mg/kg
LD50
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Intraperitoneal
Mouse
650 MG/KG
LD50
Remarks: Behavioral:Altered sleep time (including change in
righting reflex). Behavioral:Somnolence (general depressed
activity). Lungs, Thorax, or Respiration:Dyspnea.
Intravenous
Mouse
324 MG/KG
LD50
Oral
Rabbit
1040 mg/kg
LD50
Remarks: Behavioral:Somnolence (general depressed activity).
Skin
Rabbit
2000 mg/kg
LD50
Oral
Guinea pig
2500 mg/kg
LD50
Oral
Bird (wild)
100 mg/kg
LD50
IRRITATION DATA
Skin
Man
16 mg
48H
Remarks: Mild irritation effect
Skin
Rabbit
100 mg
24H
Remarks: Moderate irritation effect
Skin
Pig
100 %
Remarks: Moderate irritation effect
NTP CARCINOGEN LIST
Rating: No evidence.
Species: Mouse/rat
Route: Gavage
CHRONIC EXPOSURE - MUTAGEN
Species: Rat
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Dose: 10 MMOL/L
Cell Type: liver
Mutation test: DNA damage
Species: Mouse
Dose: 250 MG/L (+S9)
Cell Type: lymphocyte
Mutation test: Mutation in microorganisms
Species: Hamster
Dose: 4 UG/L
Cell Type: ovary
Mutation test: Cytogenetic analysis
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Mouse
Dose: 6 GM/KG
Route of Application: Oral
Exposure Time: (6-13D PREG)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain).
Section 12 - Ecological Information
ACUTE ECOTOXICITY TESTS
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 24 h
Value: 55 mg/l
Test Type: LC50 Fish
Species: Lepomis macrochirus (Bluegill)
Time: 96 h
Value: 10 mg/l
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: None
Non-Hazardous for Transport: This substance is
considered to be non-hazardous for transport.
IATA
Proper Shipping Name: Aviation Regulated Liquid, N.O.S.
IATA UN Number: 3334
Hazard Class: 9
Section 15 - Regulatory Information
EU DIRECTIVES CLASSIFICATION
Symbol of Danger: Xn
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Indication of Danger: Harmful.
R: 20/22
Risk Statements: Harmful by inhalation and if swallowed.
S: 26
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Harmful.
Risk Statements: Harmful by inhalation and if swallowed.
Irritating to skin.
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
suitable protective clothing.
US Statements: Target organ(s): Central nervous system.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
TSCA INVENTORY ITEM: Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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