SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/18/2005
Date Updated: 03/11/2005
Version 1.6
Section 1 - Product and Company Information
Product Name ALUMINUM CHLORIDE, 99.99%
Product Number 294713
Brand ALDRICH
Company Sigma-Aldrich
Street Address 3050 Spruce Street
City, State, Zip, Country SAINT LOUIS MO 63103 US
Technical Phone: 314 771 5765
Emergency Phone: 414 273 3850 Ext. 5996
Fax: 800 325 5052
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
ALUMINIUM CHLORIDE ANHYDROUS 7446-70-0 No
SUBLIMED
Formula AlCl3
Synonyms Alluminio(cloruro di) (Italian) *
Aluminiumchlorid (German) * Aluminum chloride
(1:3) * Aluminum trichloride * Chlorure
d'aluminium (French) * Pearsall *
Trichloroaluminum
RTECS Number: BD0525000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Corrosive.
Causes burns. Reacts violently with water.
Possible sensitizer. Target organ(s): Lungs.
HMIS RATING
HEALTH: 3
FLAMMABILITY: 0
REACTIVITY: 2
SPECIAL HAZARD(S): Water reactive
NFPA RATING
HEALTH: 3
FLAMMABILITY: 0
REACTIVITY: 2
SPECIAL HAZARD(S): Water reactive
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately. Do not induce vomiting.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
Section 5 - Fire Fighting Measures
CONDITIONS OF FLAMMABILITY
Water hydrolyzes material liberating acidic gas which in contact
with metal surfaces can generate flammable and/or explosive
hydrogen gas.
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Use extinguishing media appropriate to surrounding
fire conditions.
Unsuitable: Do not use water.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Ventilate
area and wash spill site after material pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe dust. Do not get in eyes, on skin,
on clothing. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep tightly closed. Store in a cool dry place.
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Incompatible Materials: Do not allow contact with water
SPECIAL REQUIREMENTS
Store under inert gas. Vent periodically. May develop pressure.
Open carefully.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Government approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated
shoes. Wash thoroughly after handling.
EXPOSURE LIMITS, RTECS
Country Source Type Value
USA ACGIH TWA 2 MG(AL)/M3
New Zealand OEL
Remarks: check ACGIH TLV
Section 9 - Physical/Chemical Properties
Appearance Physical State: Solid
Property Value At Temperature or Pressure
Molecular Weight 133.34 AMU
pH 2.4 20 藲C Concentration: 100
g/l
BP/BP Range 187.7 藲C 752 mmHg
MP/MP Range 190 藲C
Freezing Point N/A
Vapor Pressure 1 mmHg 100 藲C
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density 2.44 g/cm3
Bulk Density 1,200 kg/l
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Soluble.
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N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: Do not allow water to enter container because
of violent reaction.
Materials to Avoid: Strong oxidizing agents, Alcohols Mixtures of
nitrobenzene and aluminum chloride are thermally unstable and may
lead to explosive decomposition due to a multi-step decomposition
reaction occurring above 90 degrees C, which self-accelerates with
high exothermicity producing azo- and azoxypolymers.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Aluminum oxide, Hydrogen
chloride gas.
Hazardous Decomposition Products Formed Upon Contact with Water:
Hydrogen chloride gas
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: Causes burns.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes burns.
Inhalation: Material is extremely destructive to the tissue of
the mucous membranes and upper respiratory tract. May be harmful
if inhaled.
Ingestion: May be harmful if swallowed.
SENSITIZATION
Sensitization: Prolonged or repeated exposure may cause allergic
reactions in certain sensitive individuals.
TARGET ORGAN(S) OR SYSTEM(S)
Damage to the lungs.
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. Prolonged exposure can cause: Damage to the lungs. To
the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
TOXICITY DATA
Oral
Rat
3450 mg/kg
LD50
Remarks: Brain and Coverings:Other degenerative changes.
Gastrointestinal:Other changes. Kidney, Ureter,
Bladder:Hematuria.
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Oral
Mouse
1130 mg/kg
LD50
Skin
Rabbit
> 2000 mg/kg
LD50
CHRONIC EXPOSURE - TERATOGEN
Result: Laboratory experiments have shown teratogenic effects.
Species: Rat
Dose: 500 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (14-18D PREG)
Result: Specific Developmental Abnormalities: Musculoskeletal
system.
CHRONIC EXPOSURE - MUTAGEN
Species: Rat
Dose: 500 UMOL/L
Cell Type: Ascites tumor
Mutation test: DNA damage
Species: Mouse
Route: Intraperitoneal
Dose: 444 MG/KG
Mutation test: Cytogenetic analysis
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Result: Overexposure may cause reproductive disorder(s) based on
tests with laboratory animals.
Species: Rat
Dose: 11512 MG/KG
Route of Application: Oral
Exposure Time: (8-22D PREG)
Result: Effects on Newborn: Weaning or lactation index (e.g., #
alive at weaning per # alive at day 4). Effects on Newborn:
Growth statistics (e.g., reduced weight gain). Effects on
Newborn: Behavioral.
Species: Rat
Dose: 5723 MG/KG
Route of Application: Oral
Exposure Time: (1-21D PREG)
Result: Effects on Newborn: Other neonatal measures or effects.
Effects on Newborn: Behavioral.
Species: Rat
Dose: 900 MG/KG
Route of Application: Oral
Exposure Time: (15D PREG)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain). Effects on Newborn: Behavioral. Effects on
Newborn: Delayed effects.
Species: Rat
Dose: 375 MG/KG
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Route of Application: Intraperitoneal
Exposure Time: (9-13D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Embryo or Fetus: Fetotoxicity (except death, e.g.,
stunted fetus).
Species: Mouse
Dose: 425 MG/KG
Route of Application: Oral
Exposure Time: (MULTIGENERATIONS)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain).
Species: Mouse
Dose: 600 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (6-15D PREG)
Result: Maternal Effects: Other effects. Effects on Embryo or
Fetus: Fetotoxicity (except death, e.g., stunted fetus).
Section 12 - Ecological Information
ACUTE ECOTOXICITY TESTS
Test Type: LC50 Fish
Species: Carassius auratus (Goldfish)
Time: 7 days
Value: 0.15 mg/l
Test Type: EC50 Algae
Species: Selenastrum capricornutum resp.
Time: 96 h
Value: 0.57 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 3.9 mg/l
Test Type: LC50 Fish
Species: Onchorhynchus mykiss (Rainbow trout)
Time: 96 h
Value: 6.9 mg/l
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: Aluminum chloride, anhydrous
UN#: 1726
Class: 8
Packing Group: Packing Group II
Hazard Label: Corrosive
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PIH: Not PIH
IATA
Proper Shipping Name: Aluminium chloride, anhydrous
IATA UN Number: 1726
Hazard Class: 8
Packing Group: II
Section 15 - Regulatory Information
EU DIRECTIVES CLASSIFICATION
Symbol of Danger: C
Indication of Danger: Corrosive.
R: 34
Risk Statements: Causes burns.
S: 7/8 28 45
Safety Statements: Keep container tightly closed and dry. After
contact with skin, wash immediately with plenty of soap-suds. In
case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Corrosive.
Risk Statements: Causes burns. Reacts violently with water.
Safety Statements: Do not breathe dust. In case of contact with
eyes, rinse immediately with plenty of water and seek medical
advice. Wear suitable protective clothing, gloves, and eye/face
protection. In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible).
US Statements: Possible sensitizer. Target organ(s): Lungs.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
TSCA INVENTORY ITEM: Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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