SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/18/2005
Date Updated: 03/06/2004
Version 1.3
Section 1 - Product and Company Information
Product Name A-NAPHTHOL 99+%
Product Number N1000
Brand SIGMA
Company Sigma-Aldrich
Street Address 3050 Spruce Street
City, State, Zip, Country SAINT LOUIS MO 63103 US
Technical Phone: 314 771 5765
Emergency Phone: 414 273 3850 Ext. 5996
Fax: 800 325 5052
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
1-NAPHTHOL 90-15-3 No
Formula C10H8O
Synonyms Basf Ursol ERN * C.I. 76605 * C.I. Oxidation Base
33 * Durafur developer D * Fouramine ERN *
Fourrine 99 * Fourrine ERN * Furro ER *
alpha-Hydroxynaphthalene * 1-Hydroxynaphthalene *
Nako TRB * 1-Naphthalenol * alpha-Naphthol *
Tertral ERN * Ursol ERN * Zoba ERN
RTECS Number: QL2800000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Toxic (USA) Harmful (EU).
Harmful in contact with skin and if swallowed. Irritating to
respiratory system and skin. Risk of serious damage to eyes.
Readily absorbed through skin. Target organ(s): Eyes. Kidneys.
HMIS RATING
HEALTH: 2*
FLAMMABILITY: 0
REACTIVITY: 1
NFPA RATING
HEALTH: 2
FLAMMABILITY: 0
REACTIVITY: 1
*additional chronic hazards present.
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
Section 5 - Fire Fighting Measures
FLASH POINT
257 藲F 125 藲C Method: closed cup
EXPLOSION LIMITS
Lower: 0.8 % Upper: 5 %
AUTOIGNITION TEMP
542 藲C
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe dust. Avoid contact with eyes,
skin, and clothing. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep tightly closed. Store in a cool dry place. Store
under nitrogen.
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SPECIAL REQUIREMENTS
Store under inert gas. Air and light sensitive.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Mechanical exhaust required. Safety shower and eye bath.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Government approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
Section 9 - Physical/Chemical Properties
Appearance Physical State: Solid
Property Value At Temperature or Pressure
Molecular Weight 144.17 AMU
pH N/A
BP/BP Range 278 - 280 藲C 760 mmHg
MP/MP Range 95 藲C
Freezing Point N/A
Vapor Pressure 1.7 mmHg 100 藲C
Vapor Density 4.5 g/l 120 藲C
Saturated Vapor Conc. N/A
SG/Density N/A
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient Log Kow: 2.85
Decomposition Temp. N/A
Flash Point 257 藲F 125 藲C Method: closed cup
Explosion Limits Lower: 0.8 %
Upper: 5 %
Flammability N/A
Autoignition Temp 542 藲C
Refractive Index 1.6224 99 藲C
Optical Rotation N/A
Miscellaneous Data N/A
Solubility Other Solvents: VERYSOLUBLE IN ETHANOL,
ETHER SOLUBLE IN ACETONE FREELY SOLUBLE IN
BENZENE ALKALI
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents, Strong bases.
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HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: Causes severe skin irritation.
Skin Absorption: Harmful if absorbed through skin.
Eye Contact: Causes severe eye irritation.
Inhalation: Material is extremely destructive to the tissue of
the mucous membranes and upper respiratory tract. May be harmful
if inhaled.
Ingestion: Harmful if swallowed.
TARGET ORGAN(S) OR SYSTEM(S)
Eyes. Liver. Kidneys. Blood.
SIGNS AND SYMPTOMS OF EXPOSURE
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. To the best of our knowledge, the chemical, physical,
and toxicological properties have not been thoroughly
investigated.
TOXICITY DATA
Oral
Rat
1870 mg/kg
LD50
Inhalation
Rat
> 420 mg/m3
LC50
Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Eye:Lacrimation. Gastrointestinal:Changes in structure or
function of salivary glands.
Intraperitoneal
Rat
250 MG/KG
LD50
Oral
Mouse
275 mg/kg
LD50
Oral
Cat
134 mg/kg
LD50
Oral
Rabbit
9000 mg/kg
LD50
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Skin
Rabbit
880 mg/kg
LD50
Oral
Guinea pig
2000 mg/kg
LD50
IRRITATION DATA
Skin
Rabbit
500 mg
24H
Remarks: Severe irritation effect
Skin
Rabbit
550 mg
Remarks: Open irritation test
Eyes
Rabbit
1 mg
Remarks: Severe irritation effect
CHRONIC EXPOSURE - MUTAGEN
Mutation test: Histidine reversion (Ames)
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Mouse
Dose: 90 MG/KG
Route of Application: Subcutaneous
Exposure Time: (6-14D PREG)
Result: Effects on Fertility: Litter size (e.g.; # fetuses per
litter; measured before birth). Effects on Embryo or Fetus:
Fetotoxicity (except death, e.g., stunted fetus).
Section 12 - Ecological Information
ACUTE ECOTOXICITY TESTS
Test Type: EC50 Algae
Time: 50 - 72 h
Value: 8 - 65 mg/l
Test Type: LC50 Fish
Species: Pimephales promelas (Fathead minnow)
Time: 96 h
Value: 4.1 - 4.70 mg/l
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
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afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: Toxic solids, organic, n.o.s.
UN#: 2811
Class: 6.1
Packing Group: Packing Group III
Hazard Label: Toxic substances.
PIH: Not PIH
IATA
Proper Shipping Name: Toxic solid, organic, n.o.s.
IATA UN Number: 2811
Hazard Class: 6.1
Packing Group: III
Section 15 - Regulatory Information
EU DIRECTIVES CLASSIFICATION
Symbol of Danger: Xn
Indication of Danger: Harmful.
R: 21/22 37/38 41
Risk Statements: Harmful in contact with skin and if swallowed.
Irritating to respiratory system and skin. Risk of serious
damage to eyes.
S: 22 26 37/39
Safety Statements: Do not breathe dust. In case of contact with
eyes, rinse immediately with plenty of water and seek medical
advice. Wear suitable gloves and eye/face protection.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Toxic (USA) Harmful (EU).
Risk Statements: Harmful in contact with skin and if swallowed.
Irritating to respiratory system and skin. Risk of serious
damage to eyes.
Safety Statements: Do not breathe dust. In case of contact with
eyes, rinse immediately with plenty of water and seek medical
advice. Wear suitable protective clothing, gloves, and eye/face
protection. In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible).
US Statements: Readily absorbed through skin. Target organ(s):
Eyes. Kidneys.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
TSCA INVENTORY ITEM: Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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