SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/20/2005
Date Updated: 05/03/2004
Version 1.4
Section 1 - Product and Company Information
Product Name CITRIC ACID, 99.5+%, A.C.S. REAGENT
Product Number 251275
Brand ALDRICH
Company Sigma-Aldrich
Street Address 3050 Spruce Street
City, State, Zip, Country SAINT LOUIS MO 63103 US
Technical Phone: 314 771 5765
Emergency Phone: 414 273 3850 Ext. 5996
Fax: 800 325 5052
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
CITRIC ACID ANHYDROUS 77-92-9 No
Formula C6H8O7
Synonyms Aciletten * Anhydrous citric acid * Citretten *
Citric acid, anhydrous * Citro *
2-Hydroxy-1,2,3-propanetricarboxylic acid *
beta-Hydroxytricarballylic acid * Kyselina
citronova (Czech) * Kyselina
2-hydroxy-1,2,3-propantrikarbonova (Czech) * NSC
30279 * 1,2,3-Propanetricarboxylic acid,
2-hydroxy-
RTECS Number: GE7350000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Irritant.
Risk of serious damage to eyes.
Possible sensitizer.
HMIS RATING
HEALTH: 2
FLAMMABILITY: 0
REACTIVITY: 0
NFPA RATING
HEALTH: 2
FLAMMABILITY: 0
REACTIVITY: 0
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of contact, immediately wash skin with soap and copious
amounts of water.
EYE EXPOSURE
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
Section 5 - Fire Fighting Measures
FLASH POINT
N/A
EXPLOSION LIMITS
Lower: 8 %
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe dust. Avoid contact with eyes,
skin, and clothing. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep tightly closed.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
PERSONAL PROTECTIVE EQUIPMENT
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Respiratory: Government approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
Section 9 - Physical/Chemical Properties
Appearance Physical State: Solid
Property Value At Temperature or Pressure
Molecular Weight 192.12 AMU
pH N/A
BP/BP Range N/A
MP/MP Range 155 - 157 掳C
Freezing Point N/A
Vapor Pressure N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density N/A
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits Lower: 8 %
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
Solubility N/A
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Oxidizing agents, Bases, Reducing agents,
Nitrates.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
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Eye Contact: Causes severe eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
SENSITIZATION
Sensitization: Prolonged or repeated exposure may cause allergic
reactions in certain sensitive individuals.
SIGNS AND SYMPTOMS OF EXPOSURE
Exposure can cause: Vomiting. Diarrhea. Damage to tooth enamel.
Dermatitis. To the best of our knowledge, the chemical,
physical, and toxicological properties have not been thoroughly
investigated.
TOXICITY DATA
Oral
Rat
3000 mg/kg
LD50
Intraperitoneal
Rat
290 MG/KG
LD50
Subcutaneous
Rat
5500 MG/KG
LD50
Remarks: Lungs, Thorax, or Respiration:Other changes. Other
changes
Oral
Mouse
5040 mg/kg
LD50
Remarks: Lungs, Thorax, or Respiration:Other changes. Other
changes
Intraperitoneal
Mouse
903 MG/KG
LD50
Subcutaneous
Mouse
2700 MG/KG
LD50
Remarks: Lungs, Thorax, or Respiration:Other changes. Other
changes
Intravenous
Mouse
42 MG/KG
LD50
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Cyanosis. Gastrointestinal:Changes
in structure or function of salivary glands.
Intravenous
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Rabbit
330 MG/KG
LD50
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Cyanosis. Gastrointestinal:Changes
in structure or function of salivary glands.
IRRITATION DATA
Skin
Rabbit
500 mg
24H
Remarks: Mild irritation effect
Eyes
Rabbit
0.75 mg
24H
Remarks: Severe irritation effect
Section 12 - Ecological Information
No data available.
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: None
Non-Hazardous for Transport: This substance is
considered to be non-hazardous for transport.
IATA
Non-Hazardous for Air Transport: Non-hazardous for air
transport.
Section 15 - Regulatory Information
EU ADDITIONAL CLASSIFICATION
Symbol of Danger: Xi
Indication of Danger: Irritant.
R: 41
Risk Statements: Risk of serious damage to eyes.
S: 26 39
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
eye/face protection.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Irritant.
Risk Statements: Risk of serious damage to eyes.
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
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suitable protective clothing.
US Statements: Possible sensitizer.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
TSCA INVENTORY ITEM: Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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