SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/20/2005
Date Updated: 05/14/2004
Version 1.7
Section 1 - Product and Company Information
Product Name ADIPIC ACID, 99%
Product Number A26357
Brand ALDRICH
Company Sigma-Aldrich
Street Address 3050 Spruce Street
City, State, Zip, Country SAINT LOUIS MO 63103 US
Technical Phone: 314 771 5765
Emergency Phone: 414 273 3850 Ext. 5996
Fax: 800 325 5052
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
ADIPIC ACID 124-04-9 No
Formula C6H10O4
Synonyms Acifloctin * Acinetten * Adilactetten * Adipic
acid (ACGIH) * Adipinic acid *
1,4-Butanedicarboxylic acid * Hexanedioic acid *
1,6-Hexanedioic acid * Kyselina adipova (Czech) *
Molten adipic acid
RTECS Number: AU8400000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Irritant.
Irritating to eyes.
HMIS RATING
HEALTH: 2
FLAMMABILITY: 0
REACTIVITY: 0
NFPA RATING
HEALTH: 2
FLAMMABILITY: 0
REACTIVITY: 0
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of contact, immediately wash skin with soap and copious
amounts of water.
EYE EXPOSURE
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
INFORMATION FOR PHYSICIAN
Contamination of the eyes should be treated by immediate and
prolonged irrigation with copious amounts of water.
Section 5 - Fire Fighting Measures
EXPLOSION DATA
Dust Potential: This material, like most materials in powder
form, is capable of creating a dust explosion.
FLASH POINT
385 掳F 196 掳C Method: closed cup
AUTOIGNITION TEMP
420 掳C
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
ENVIRONMENTAL PRECAUTION(S)
Avoid contaminating water supply. Avoid contaminating sewers and
waterways with this material.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe dust. Avoid contact with eyes,
skin, and clothing. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep tightly closed. Keep away from heat, sparks, and
open flame. Store in a cool dry place.
ALDRICH - A26357 www.sigma-aldrich.com Page 2
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required. Ventilate
area - especially low places where heavy vapors might collect.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Government approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
EXPOSURE LIMITS, RTECS
Country Source Type Value
USA USA ACGIH ACGIH TWA TWA 5 MG/M3 5 MG/M3
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 5 mg/m3
Poland NDSCh 10 mg/m3
Poland NDSP
Remarks: {OELS ARE VALID FOR DUSTS} PY拢Y
Section 9 - Physical/Chemical Properties
Appearance Physical State: Solid
Color: White
Form: Fine crystals
Property Value At Temperature or Pressure
Molecular Weight 146.14 AMU
pH 2-3 25 掳C Concentration:
24.9 g/l
BP/BP Range 265 掳C 100 mmHg
MP/MP Range 151 掳C
Freezing Point N/A
Vapor Pressure 1 mmHg 159.5 掳C
Vapor Density 5 g/l
Saturated Vapor Conc. N/A
SG/Density N/A
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient Log Kow: 0.093 25 掳C
Decomposition Temp. N/A
Flash Point 385 掳F 196 掳C Method: closed cup
Explosion Limits N/A
Flammability N/A
Autoignition Temp 420 掳C
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
ALDRICH - A26357 www.sigma-aldrich.com Page 3
Solubility Solvent: 0.1 g/ml MeOH clear, colorless
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
TOXICITY DATA
Oral
Rat
5,050 mg/kg
LD50
Skin
Rabbit
7,940 mg/kg
LD50
Oral
Rat
> 11000 mg/kg
LD50
Intraperitoneal
Rat
275 MG/KG
LD50
Remarks: Behavioral:Somnolence (general depressed activity).
Gastrointestinal:Other changes. Blood: Hemorrhage.
Oral
Mouse
1900 mg/kg
LD50
Remarks: Gastrointestinal:Other changes.
Intravenous
Mouse
680 MG/KG
LD50
ALDRICH - A26357 www.sigma-aldrich.com Page 4
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Blood: Hemorrhage.
Oral
Rabbit
> 11000 mg/kg
LD50
IRRITATION DATA
Eyes
Rabbit
20 mg
24H
Remarks: Moderate irritation effect
Section 12 - Ecological Information
ACUTE ECOTOXICITY TESTS
Test Type: LC50 Fish
Species: Onchorhynchus mykiss (Rainbow trout)
Time: 48 h
Value: 100 mg/l
Test Type: LC50 Fish
Species: Pimephales promelas (Fathead minnow)
Time: 96 h
Value: 97 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 85.7 mg/l
Test Type: EC50 Algae
Species: Scenedesmus subspicatus
Time: 72 h
Value: 31.3 mg/l
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: Environmentally hazardous
substances, solid, n.o.s.
UN#: 3077
Class: 9
Packing Group: Packing Group III
Hazard Label: Class 9
PIH: Not PIH
IATA
Non-Hazardous for Air Transport: Non-hazardous for air
ALDRICH - A26357 www.sigma-aldrich.com Page 5
transport.
Section 15 - Regulatory Information
EU DIRECTIVES CLASSIFICATION
Symbol of Danger: Xi
Indication of Danger: Irritant.
R: 36
Risk Statements: Irritating to eyes.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Irritant.
Risk Statements: Irritating to eyes.
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
suitable protective clothing.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
TSCA INVENTORY ITEM: Yes Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
ALDRICH - A26357 www.sigma-aldrich.com Page 6
|